iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ata-000791

Ensembl Protein ID

EMT08232

UniProt Accession

M8AUU9; M8AUU9_AEGTA

Genbank Protein ID

EMT08232.1

Protein Name

Ubiquitin carboxyl-terminal hydrolase 12

Genbank Nucleotide ID

KD569133

Gene Name

F775_06994

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
F775_06994	EMT08232	EMT08232

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.70e-70	238.0	200	523

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqqDaqEflaflld 101
           +GlkN+g+tCYmNS+LQ+L++ip +r+++ +     ++ ++++ p+g++  +lq+lf +l ++++++v+++el+k++++    +++++q+D+qE+ ++l +
   Q: 200  VGLKNQGATCYMNSLLQTLYHIPYFRKAVYH-----MPTTENDMPSGSIPLALQSLFYKL-QYSDNSVATKELTKSFGWDT--YDSFMQHDVQELNRVLCE 292
           6******************************.....555556789***************.88899************877..67**************** PP
   S: 102  qleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkkeslqdcLesftkeeeleg 202
           +le+++                          k +  + +i++lF+g+  + i c + d +s+r+e+f+dl+l+v+g +     ++  +++++++ e+leg
   Q: 293  KLEDKM--------------------------KGTVVEGTIEQLFEGHHINYIECINVDYKSNRKESFYDLQLDVKGCR-----DVYASFDKYVEVERLEG 362
           ******..........................7899*******************************************.....9**************** PP
   S: 203  enkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdls....pfctspeekqkekkkYeLiavvvHsGslssGHYvayv 299
           +nky+ e+  ++q+a+k + +  +P+vL l+LkRf+++  ++   kin+++efpl+Ldl+    +++t + +  + ++ Y L++v+vHsG++++GHY+a++
   Q: 363  DNKYQAEQH-GLQDARKGVLFLDFPPVLQLQLKRFEYDYMRDTMVKINDRYEFPLQLDLDkddgKYLTPDAD-RSIRNLYTLHSVLVHSGGVHGGHYYAFI 461
           ******996.79***********************************************9888778887555.556************************* PP
   S: 300  kn.ekgkWllfdDskVtevkeeevleetg.......................staYvlfYkr 337
           +   +++W++fdD++Vt+ + ++ lee+                        s+aY+l+Y r
   Q: 462  RPtLSDQWYKFDDERVTKEDTKKALEEQYggeeelpqvnpgfnntpfkftkySNAYMLVYIR 523
           *945677*************9999997779******************************87 PP

Organism

Aegilops tauschii

Protein Sequence
(Fasta)

MTMMTPSPLE QQEDEEMLVP HQELSTADAA QPMEVVAQTE PTNTAESQAP EDPQTSRFTW 60
TIENFTRVSG KKHYSDVFVV GGFKWRVLIF PKGNNVDHLS MYLDVADSGN LPYGWSRYAQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACTATGA TGACCCCTTC CCCTCTCGAG GTACGTGCCC TATCTCCTCA CTCGCCTGAT 60
CTCCCCGGCT CCTCTCGCCC CACTGCCCCT TTCCGATCGG GGGTCTCCTC TTTCTCCATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0378--Hydrolase

Interpro

IPR002083--MATH/TRAF_dom
IPR001394--Peptidase_C19_UCH
IPR008974--TRAF-like
IPR024729--USP7_ICP0-binding_dom
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50144--MATH
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00917--MATH
PF00443--UCH
PF12436--USP7_ICP0_bdg

SMART

SM00061--MATH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

ats:F775_06994

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ago-007849	Ashbya gossypii	36.21	7.00e-129	454.00
IUUC-Ani-009257	Aspergillus nidulans	29.83	1.00e-31	132.00
IUUC-Cel-018219	Caenorhabditis elegans	36.64	1.00e-84	307.00
IUUC-Cre-022708	Chlamydomonas reinhardtii	54.69	2.00e-141	494.00
IUUC-Cho-025006	Choloepus hoffmanni	37.50	3.00e-55	209.00
IUUC-Cme-027103	Cyanidioschyzon merolae	38.05	2.00e-123	436.00
IUUC-Dor-030611	Dipodomys ordii	49.85	2.00e-82	300.00
IUUC-Eeu-035292	Erinaceus europaeus	38.98	5.00e-63	235.00
IUUC-Kpa-049121	Komagataella pastoris	36.03	8.00e-118	417.00
IUUC-Loc-052234	Lepisosteus oculatus	38.66	2.00e-126	446.00
IUUC-Opr-071001	Ochotona princeps	38.29	1.00e-121	430.00
IUUC-Pma-094648	Petromyzon marinus	39.54	6.00e-138	484.00
IUUC-Pca-100543	Procavia capensis	37.33	2.00e-91	330.00
IUUC-Ptt-103720	Puccinia triticina	43.50	2.00e-145	509.00
IUUC-Sce-106230	Saccharomyces cerevisiae	36.17	2.00e-121	429.00
IUUC-Sja-107690	Schizosaccharomyces japonicus	38.96	1.00e-125	444.00
IUUC-Tsy-119277	Tarsius syrichta	43.27	1.00e-72	267.00
IUUC-Tbe-127696	Tupaia belangeri	44.13	5.00e-69	255.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence