iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Gga-040537

Ensembl Protein ID

ENSGALP00000042469.2

UniProt Accession

R4GJY8; R4GJY8_CHICK

Genbank Protein ID

ENSGALP00000042469

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AADN04000057

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000026380.3	ENSGALT00000043007.2	ENSGALP00000042469.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	2.40e-42	144.3	5	125

Active Site

Position(s)	Description	Evidence
72	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 14   pegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekWspalsvesvl 102
            +gisa p+++ +l++w  +i G ++t Ye+  +kl++efp+ YP+++P+v+flt+++hPnv+++G++Cl+ilk  ekWs+ ++v+++l
   Q: 5    DKGISAFPESD-NLFRWIGTIDGAAGTAYEELRYKLSLEFPSGYPYTAPTVRFLTPCYHPNVDAQGNICLDILK--EKWSALYDVRTIL 90
           57999******.9************************************************************9..************* PP
   S: 103  lsiqsllaepnpesplneeaaellkknreeykkkvr 138
           lsiqsllaepn++spln++aael+k++ + ykk +r
   Q: 91   LSIQSLLAEPNIDSPLNTHAAELWKNQAA-YKKYLR 125
           ************************88876.999876 PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

MMSGDKGISA FPESDNLFRW IGTIDGAAGT AYEELRYKLS LEFPSGYPYT APTVRFLTPC 60
YHPNVDAQGN ICLDILKEKW SALYDVRTIL LSIQSLLAEP NIDSPLNTHA AELWKNQAAY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGGCTACG GCCGCCCGCG GCTCTGTGGG GAAGAGGTGA GGCCGGGCCG GGGGCCGGAG 60
GGGGTTGGGC TGCCCTGCCC TGCCCTGCCC TGCGCTGCCC GTGGTTGCCG GTGCGGACCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005680--C:anaphase-promoting complex
GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0031145--P:anaphase-promoting complex-dependent catabolic process
GO:0010458--P:exit from mitosis
GO:0010994--P:free ubiquitin chain polymerization
GO:0031536--P:positive regulation of exit from mitosis
GO:0070979--P:protein K11-linked ubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0000209--P:protein polyubiquitination
GO:0030071--P:regulation of mitotic metaphase/anaphase transition

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001924	Ailuropoda melanoleuca	84.78	3.00e-68	250.00
IUUC-Atr-002538	Amborella trichopoda	61.31	4.00e-48	183.00
IUUC-Aly-006086	Arabidopsis lyrata	62.50	1.00e-46	179.00
IUUC-Ath-006897	Arabidopsis thaliana	61.72	5.00e-46	176.00
IUUC-Acl-008223	Aspergillus clavatus	60.32	3.00e-34	137.00
IUUC-Afl-008675	Aspergillus flavus	60.32	7.00e-34	136.00
IUUC-Afu-008997	Aspergillus fumigatus	59.52	3.00e-33	134.00
IUUC-Ani-009470	Aspergillus nidulans	59.52	1.00e-33	135.00
IUUC-Ang-009648	Aspergillus niger	60.32	6.00e-34	136.00
IUUC-Aor-009977	Aspergillus oryzae	61.67	2.00e-32	130.00
IUUC-Ate-010318	Aspergillus terreus	59.52	1.00e-33	135.00
IUUC-Ame-011302	Astyanax mexicanus	78.12	3.00e-59	220.00
IUUC-Bta-013101	Bos taurus	86.76	4.00e-70	256.00
IUUC-Bci-013787	Botrytis cinerea	58.27	3.00e-38	150.00
IUUC-Bdi-014144	Brachypodium distachyon	67.19	2.00e-52	198.00
IUUC-Bol-015613	Brassica oleracea	62.50	4.00e-47	180.00
IUUC-Bra-017248	Brassica rapa	62.50	3.00e-47	180.00
IUUC-Cfa-020588	Canis familiaris	86.76	4.00e-70	256.00
IUUC-Cpo-021384	Cavia porcellus	88.24	1.00e-70	258.00
IUUC-Csa-023437	Chlorocebus sabaeus	87.50	7.00e-71	259.00
IUUC-Cho-024330	Choloepus hoffmanni	92.17	5.00e-62	228.00
IUUC-Csv-025933	Ciona savignyi	66.92	1.00e-51	194.00
IUUC-Cgl-026494	Colletotrichum gloeosporioides	57.26	6.00e-36	142.00
IUUC-Cme-027266	Cyanidioschyzon merolae	59.09	3.00e-37	147.00
IUUC-Dre-027375	Danio rerio	76.56	2.00e-58	218.00
IUUC-Dno-029921	Dasypus novemcinctus	86.03	3.00e-69	253.00
IUUC-Dor-030209	Dipodomys ordii	82.35	9.00e-66	242.00
IUUC-Dse-031516	Dothistroma septosporum	50.00	1.00e-32	132.00
IUUC-Dme-031942	Drosophila melanogaster	64.12	7.00e-50	189.00
IUUC-Eca-034073	Equus caballus	87.50	1.00e-70	258.00
IUUC-Eeu-034854	Erinaceus europaeus	86.79	1.00e-52	198.00
IUUC-Fca-035666	Felis catus	87.50	1.00e-70	258.00
IUUC-Fal-037652	Ficedula albicollis	94.39	8.00e-58	214.00
IUUC-Fox-037793	Fusarium oxysporum	59.68	1.00e-37	149.00
IUUC-Fso-038151	Fusarium solani	59.68	8.00e-38	149.00
IUUC-Gmo-038894	Gadus morhua	81.98	7.00e-53	198.00
IUUC-Ggr-039730	Gaeumannomyces graminis	51.82	8.00e-30	122.00
IUUC-Gac-041346	Gasterosteus aculeatus	74.22	2.00e-56	211.00
IUUC-Gma-043989	Glycine max	64.06	7.00e-49	186.00
IUUC-Ggo-045594	Gorilla gorilla	86.96	8.00e-70	255.00
IUUC-Hsa-046216	Homo sapiens	88.24	3.00e-71	260.00
IUUC-Hvu-047797	Hordeum vulgare	65.15	1.00e-50	192.00
IUUC-Itr-048402	Ictidomys tridecemlineatus	87.50	1.00e-70	258.00
IUUC-Kpa-049294	Komagataella pastoris	62.31	5.00e-44	170.00
IUUC-Lch-049761	Latimeria chalumnae	77.04	1.00e-60	225.00
IUUC-Lpe-051089	Leersia perrieri	65.15	3.00e-51	194.00
IUUC-Loc-052297	Lepisosteus oculatus	81.25	1.00e-61	229.00
IUUC-Lma-053214	Leptosphaeria maculans	52.21	7.00e-39	152.00
IUUC-Laf-054468	Loxodonta africana	86.23	1.00e-69	254.00
IUUC-Mcc-055338	Macaca mulatta	87.50	7.00e-71	259.00
IUUC-Meu-056147	Macropus eugenii	83.82	7.00e-68	249.00
IUUC-Mor-057239	Magnaporthe oryzae	57.26	6.00e-36	142.00
IUUC-Mpo-057491	Magnaporthe poae	58.06	8.00e-37	145.00
IUUC-Mtr-057687	Medicago truncatula	64.46	3.00e-45	174.00
IUUC-Mla-058880	Melampsora laricipopulina	60.94	8.00e-45	172.00
IUUC-Mga-059929	Meleagris gallopavo	100.00	7.00e-56	207.00
IUUC-Mvi-060528	Microbotryum violaceum	61.24	2.00e-41	162.00
IUUC-Mmr-060747	Microcebus murinus	91.38	1.00e-62	231.00
IUUC-Mdo-062343	Monodelphis domestica	85.29	9.00e-69	251.00
IUUC-Mmu-063563	Mus musculus	86.03	3.00e-69	253.00
IUUC-Mac-064823	Musa acuminata	62.04	7.00e-50	189.00
IUUC-Mpu-065746	Mustela putorius furo	85.51	1.00e-68	251.00
IUUC-Mlu-067388	Myotis lucifugus	84.78	8.00e-68	249.00
IUUC-Nfi-068577	Neosartorya fischeri	61.11	4.00e-34	137.00
IUUC-Ncr-068803	Neurospora crassa	55.38	2.00e-30	124.00
IUUC-Opr-070902	Ochotona princeps	86.03	4.00e-69	253.00
IUUC-Ont-071672	Oreochromis niloticus	75.38	2.00e-58	217.00
IUUC-Oan-073728	Ornithorhynchus anatinus	80.00	2.00e-37	146.00
IUUC-Ocu-074566	Oryctolagus cuniculus	87.50	2.00e-70	257.00
IUUC-Oba-075538	Oryza barthii	66.67	7.00e-52	195.00
IUUC-Obr-076757	Oryza brachyantha	70.65	7.00e-37	144.00
IUUC-Ogu-078467	Oryza glumaepatula	66.67	4.00e-52	197.00
IUUC-Oin-079533	Oryza indica	65.91	4.00e-51	192.00
IUUC-Olo-080673	Oryza longistaminata	67.42	3.00e-52	196.00
IUUC-Ome-081483	Oryza meridionalis	66.67	7.00e-52	196.00
IUUC-Oni-082321	Oryza nivara	66.67	4.00e-52	197.00
IUUC-Opu-083245	Oryza punctata	66.41	3.00e-50	190.00
IUUC-Oru-084641	Oryza rufipogon	63.57	3.00e-50	191.00
IUUC-Osa-085992	Oryza sativa	66.67	4.00e-52	197.00
IUUC-Ola-086807	Oryzias latipes	73.88	2.00e-59	220.00
IUUC-Olu-087834	Ostreococcus lucimarinus	67.97	7.00e-50	188.00
IUUC-Oga-088699	Otolemur garnettii	85.61	2.00e-69	254.00
IUUC-Oar-089542	Ovis aries	86.23	4.00e-69	253.00
IUUC-Ptr-091069	Pan troglodytes	88.24	3.00e-71	260.00
IUUC-Pan-092533	Papio anubis	86.23	2.00e-69	254.00
IUUC-Psi-093206	Pelodiscus sinensis	86.92	6.00e-54	201.00
IUUC-Pma-094607	Petromyzon marinus	75.00	7.00e-57	212.00
IUUC-Pno-094829	Phaeosphaeria nodorum	58.40	1.00e-39	154.00
IUUC-Ppa-095861	Physcomitrella patens	65.91	4.00e-51	193.00
IUUC-Pfo-096836	Poecilia formosa	76.15	1.00e-59	221.00
IUUC-Pab-098707	Pongo abelii	88.24	3.00e-71	260.00
IUUC-Pop-099870	Populus trichocarpa	64.84	5.00e-49	186.00
IUUC-Pca-100661	Procavia capensis	87.50	1.00e-70	258.00
IUUC-Ppe-101289	Prunus persica	64.06	3.00e-48	183.00
IUUC-Pva-103235	Pteropus vampyrus	81.62	2.00e-62	231.00
IUUC-Pte-104292	Pyrenophora teres	56.80	2.00e-38	150.00
IUUC-Rno-105501	Rattus norvegicus	86.03	2.00e-69	254.00
IUUC-Sce-106133	Saccharomyces cerevisiae	56.80	4.00e-36	143.00
IUUC-Sha-107205	Sarcophilus harrisii	85.19	1.00e-67	248.00
IUUC-Sja-108009	Schizosaccharomyces japonicus	62.12	1.00e-43	168.00
IUUC-Spo-108136	Schizosaccharomyces pombe	60.77	8.00e-43	166.00
IUUC-Ssl-108394	Sclerotinia sclerotiorum	58.27	3.00e-38	150.00
IUUC-Smo-109459	Selaginella moellendorffii	64.52	2.00e-47	181.00
IUUC-Sit-110754	Setaria italica	64.39	8.00e-51	192.00
IUUC-Sly-111137	Solanum lycopersicum	64.84	2.00e-48	184.00
IUUC-Stu-112305	Solanum tuberosum	64.84	1.00e-48	185.00
IUUC-Sbi-114299	Sorghum bicolor	60.45	2.00e-47	181.00
IUUC-Ssc-115625	Sus scrofa	87.50	1.00e-70	258.00
IUUC-Tni-120070	Tetraodon nigroviridis	71.09	4.00e-54	202.00
IUUC-Tca-121158	Theobroma cacao	64.84	5.00e-49	186.00
IUUC-Tre-121973	Trichoderma reesei	60.48	4.00e-38	150.00
IUUC-Tvi-122496	Trichoderma virens	59.68	1.00e-37	148.00
IUUC-Tae-123596	Triticum aestivum	67.97	1.00e-52	198.00
IUUC-Tur-126818	Triticum urartu	65.52	1.00e-43	167.00
IUUC-Tme-127044	Tuber melanosporum	64.00	5.00e-37	146.00
IUUC-Ttr-128548	Tursiops truncatus	85.85	5.00e-52	196.00
IUUC-Vda-129840	Verticillium dahliae	58.06	9.00e-37	145.00
IUUC-Vvi-131685	Vitis vinifera	65.62	4.00e-49	186.00
IUUC-Xtr-132953	Xenopus tropicalis	79.56	1.00e-64	238.00
IUUC-Xma-134093	Xiphophorus maculatus	76.15	1.00e-59	221.00
IUUC-Yli-134548	Yarrowia lipolytica	60.77	2.00e-43	168.00
IUUC-Zma-135182	Zea mays	64.39	9.00e-51	192.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence