iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-045594

UUCD1 version

UUC-GoG-01015

Ensembl Protein ID

ENSGGOP00000023693.1

UniProt Accession

G3S6I6; G3S6I6_GORGO

Protein Name

Uncharacterized protein

Gene Name

UBE2C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000026061.1	ENSGGOT00000032050.1	ENSGGOP00000023693.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	2.00e-44	151.1	34	168

Active Site

Position(s)	Description	Evidence
114	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkee 89
           Rl++el++l+ +  +gisa p+++ +l++w  +i G ++t+Ye+  +kl++efp+ YP+++P+vkflt+++hPnv+++G++Cl+ilk  
   Q: 34   RLQQELMTLMMSGDKGISAFPESD-NLFKWVGTIHGAAGTVYEDLRYKLSLEFPSGYPYNAPTVKFLTPCYHPNVDTQGNICLDILK-- 119
           9***********************.9************************************************************9.. PP
   S: 90   ekWspalsvesvllsiqsll..aepnpesplneeaaellkknreeykkkv 137
           ekWs+ ++v+++llsiqsll  +epn++spln++aael+k+   ++kk +
   Q: 120  EKWSALYDVRTILLSIQSLLgaTEPNIDSPLNTHAAELWKNPT-AFKKYL 168
           ********************9999*************997655.488765 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MASQNRDPAA TSVAAARKGA EPSGGAARGP VGKRLQQELM TLMMSGDKGI SAFPESDNLF 60
KWVGTIHGAA GTVYEDLRYK LSLEFPSGYP YNAPTVKFLT PCYHPNVDTQ GNICLDILKE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAACGCGGGC GGGCGGGCCC GCAGTCCTGC AGTTGCAGTC GTGTTCTCCG AGTTCCTGTC 60
TCTCTGCCAA CGCCGCCCGG ATGGCTTCCC AAAACCGCGA CCCTGCCGCC ACTAGCGTCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005680--C:anaphase-promoting complex
GO:0005829--C:cytosol
GO:0005886--C:plasma membrane
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0031145--P:anaphase-promoting complex-dependent catabolic process
GO:0010458--P:exit from mitosis
GO:0010994--P:free ubiquitin chain polymerization
GO:0031536--P:positive regulation of exit from mitosis
GO:0070979--P:protein K11-linked ubiquitination
GO:0070936--P:protein K48-linked ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001924	Ailuropoda melanoleuca	96.13	1.00e-96	345.00
IUUC-Atr-002885	Amborella trichopoda	60.13	9.00e-52	196.00
IUUC-Aly-006086	Arabidopsis lyrata	58.08	1.00e-51	195.00
IUUC-Ath-006897	Arabidopsis thaliana	57.59	3.00e-50	191.00
IUUC-Acl-008223	Aspergillus clavatus	65.12	1.00e-37	148.00
IUUC-Afl-008675	Aspergillus flavus	53.57	8.00e-37	146.00
IUUC-Afu-008997	Aspergillus fumigatus	64.34	2.00e-36	144.00
IUUC-Ani-009470	Aspergillus nidulans	54.76	2.00e-37	148.00
IUUC-Ang-009648	Aspergillus niger	58.00	6.00e-37	146.00
IUUC-Aor-009977	Aspergillus oryzae	56.39	8.00e-30	122.00
IUUC-Ate-010318	Aspergillus terreus	50.56	1.00e-36	145.00
IUUC-Ame-011302	Astyanax mexicanus	75.58	1.00e-73	268.00
IUUC-Bta-013101	Bos taurus	96.13	2.00e-98	350.00
IUUC-Bci-013787	Botrytis cinerea	56.02	3.00e-43	167.00
IUUC-Bdi-014144	Brachypodium distachyon	67.61	2.00e-55	207.00
IUUC-Bol-015613	Brassica oleracea	56.73	1.00e-51	195.00
IUUC-Bra-017249	Brassica rapa	57.31	1.00e-51	195.00
IUUC-Cfa-020588	Canis familiaris	96.69	2.00e-95	340.00
IUUC-Cpo-021384	Cavia porcellus	96.13	1.00e-98	351.00
IUUC-Csa-024047	Chlorocebus sabaeus	98.90	6.00e-106	375.00
IUUC-Cho-024330	Choloepus hoffmanni	96.64	3.00e-66	243.00
IUUC-Cin-025365	Ciona intestinalis	56.88	1.00e-32	131.00
IUUC-Csv-025933	Ciona savignyi	61.36	4.00e-58	216.00
IUUC-Cgl-026494	Colletotrichum gloeosporioides	56.47	6.00e-43	166.00
IUUC-Cme-027266	Cyanidioschyzon merolae	50.96	3.00e-36	144.00
IUUC-Dre-027375	Danio rerio	75.58	4.00e-73	266.00
IUUC-Dno-029921	Dasypus novemcinctus	94.48	2.00e-93	334.00
IUUC-Dor-030209	Dipodomys ordii	92.82	9.00e-94	335.00
IUUC-Dse-031516	Dothistroma septosporum	53.95	1.00e-36	145.00
IUUC-Dme-031942	Drosophila melanogaster	65.52	6.00e-54	202.00
IUUC-Ete-032827	Echinops telfairi	84.69	3.00e-41	159.00
IUUC-Eca-034073	Equus caballus	97.24	7.00e-96	342.00
IUUC-Eeu-034854	Erinaceus europaeus	74.03	1.00e-66	245.00
IUUC-Fca-035666	Felis catus	97.24	7.00e-96	342.00
IUUC-Fal-037652	Ficedula albicollis	86.92	8.00e-53	197.00
IUUC-Fox-037793	Fusarium oxysporum	54.82	4.00e-42	163.00
IUUC-Fso-038151	Fusarium solani	56.71	2.00e-43	167.00
IUUC-Gmo-038894	Gadus morhua	76.25	2.00e-59	221.00
IUUC-Ggr-039730	Gaeumannomyces graminis	59.42	2.00e-33	134.00
IUUC-Gga-040537	Gallus gallus	86.96	5.00e-70	255.00
IUUC-Gac-041346	Gasterosteus aculeatus	70.79	1.00e-60	224.00
IUUC-Gma-043989	Glycine max	57.40	5.00e-53	199.00
IUUC-Hsa-046216	Homo sapiens	98.90	3.00e-104	369.00
IUUC-Hvu-047797	Hordeum vulgare	68.38	1.00e-52	198.00
IUUC-Itr-048402	Ictidomys tridecemlineatus	97.24	7.00e-96	342.00
IUUC-Kpa-049294	Komagataella pastoris	57.93	2.00e-47	181.00
IUUC-Lch-049761	Latimeria chalumnae	70.17	2.00e-71	260.00
IUUC-Lpe-051089	Leersia perrieri	62.03	1.00e-53	202.00
IUUC-Loc-052297	Lepisosteus oculatus	76.74	2.00e-72	265.00
IUUC-Lma-053214	Leptosphaeria maculans	49.68	2.00e-41	160.00
IUUC-Laf-054468	Loxodonta africana	96.69	9.00e-104	368.00
IUUC-Mcc-055338	Macaca mulatta	97.79	3.00e-103	367.00
IUUC-Meu-056147	Macropus eugenii	91.16	3.00e-92	330.00
IUUC-Mor-057239	Magnaporthe oryzae	52.98	5.00e-40	156.00
IUUC-Mpo-057491	Magnaporthe poae	60.87	5.00e-42	163.00
IUUC-Mtr-057687	Medicago truncatula	58.93	9.00e-47	179.00
IUUC-Mla-058880	Melampsora laricipopulina	64.08	2.00e-49	187.00
IUUC-Mga-059929	Meleagris gallopavo	87.00	2.00e-48	182.00
IUUC-Mvi-060528	Microbotryum violaceum	56.36	8.00e-45	173.00
IUUC-Mmr-060747	Microcebus murinus	96.93	1.00e-84	304.00
IUUC-Mdo-062343	Monodelphis domestica	92.86	3.00e-93	333.00
IUUC-Mmu-063563	Mus musculus	94.48	3.00e-96	343.00
IUUC-Mac-064823	Musa acuminata	63.64	3.00e-52	197.00
IUUC-Mpu-065746	Mustela putorius furo	97.79	5.00e-98	349.00
IUUC-Mlu-067388	Myotis lucifugus	96.69	8.00e-97	345.00
IUUC-Nfi-068577	Neosartorya fischeri	61.43	5.00e-37	146.00
IUUC-Ncr-068803	Neurospora crassa	56.25	6.00e-37	146.00
IUUC-Opr-070902	Ochotona princeps	92.31	7.00e-93	332.00
IUUC-Ont-071672	Oreochromis niloticus	68.93	4.00e-63	233.00
IUUC-Oan-073728	Ornithorhynchus anatinus	80.00	8.00e-37	144.00
IUUC-Ocu-074566	Oryctolagus cuniculus	91.76	8.00e-90	322.00
IUUC-Oba-075538	Oryza barthii	66.17	3.00e-50	189.00
IUUC-Obr-076757	Oryza brachyantha	68.09	1.00e-34	137.00
IUUC-Ogu-078467	Oryza glumaepatula	64.86	2.00e-54	204.00
IUUC-Oin-079533	Oryza indica	65.41	1.00e-49	187.00
IUUC-Olo-080673	Oryza longistaminata	66.92	1.00e-50	191.00
IUUC-Ome-081483	Oryza meridionalis	66.20	1.00e-53	202.00
IUUC-Oni-082321	Oryza nivara	64.86	2.00e-54	204.00
IUUC-Opu-083245	Oryza punctata	64.79	2.00e-52	197.00
IUUC-Oru-084641	Oryza rufipogon	62.18	1.00e-52	198.00
IUUC-Osa-085992	Oryza sativa	64.86	2.00e-54	204.00
IUUC-Ola-086807	Oryzias latipes	71.67	1.00e-70	258.00
IUUC-Olu-087834	Ostreococcus lucimarinus	69.78	2.00e-54	204.00
IUUC-Oga-088699	Otolemur garnettii	96.70	3.00e-103	367.00
IUUC-Oar-089542	Ovis aries	97.24	2.00e-97	347.00
IUUC-Ptr-091069	Pan troglodytes	98.90	3.00e-104	369.00
IUUC-Pan-092533	Papio anubis	98.90	6.00e-106	375.00
IUUC-Psi-093581	Pelodiscus sinensis	66.67	5.00e-57	213.00
IUUC-Pma-094607	Petromyzon marinus	71.51	1.00e-69	254.00
IUUC-Pno-094829	Phaeosphaeria nodorum	53.33	3.00e-41	160.00
IUUC-Ppa-095861	Physcomitrella patens	65.49	3.00e-54	204.00
IUUC-Pfo-096836	Poecilia formosa	69.32	1.00e-65	241.00
IUUC-Pab-098707	Pongo abelii	98.90	3.00e-104	369.00
IUUC-Pop-099021	Populus trichocarpa	65.49	1.00e-52	198.00
IUUC-Pca-100661	Procavia capensis	96.13	8.00e-98	348.00
IUUC-Ppe-101289	Prunus persica	56.50	6.00e-53	199.00
IUUC-Pva-103235	Pteropus vampyrus	92.27	2.00e-87	313.00
IUUC-Pte-104292	Pyrenophora teres	57.78	1.00e-41	161.00
IUUC-Rno-105501	Rattus norvegicus	95.03	3.00e-97	346.00
IUUC-Sce-106133	Saccharomyces cerevisiae	61.83	4.00e-36	143.00
IUUC-Sha-107205	Sarcophilus harrisii	92.31	7.00e-76	276.00
IUUC-Sja-108009	Schizosaccharomyces japonicus	56.32	1.00e-48	185.00
IUUC-Spo-108136	Schizosaccharomyces pombe	54.34	5.00e-49	186.00
IUUC-Ssl-108394	Sclerotinia sclerotiorum	56.02	4.00e-43	167.00
IUUC-Smo-109014	Selaginella moellendorffii	63.77	1.00e-50	192.00
IUUC-Sit-110754	Setaria italica	65.49	9.00e-54	202.00
IUUC-Sly-111137	Solanum lycopersicum	64.58	5.00e-52	196.00
IUUC-Stu-112305	Solanum tuberosum	64.38	2.00e-52	197.00
IUUC-Sbi-114299	Sorghum bicolor	62.50	3.00e-50	190.00
IUUC-Ssc-115625	Sus scrofa	96.69	7.00e-96	342.00
IUUC-Tru-118289	Takifugu rubripes	73.86	3.00e-35	139.00
IUUC-Tni-120070	Tetraodon nigroviridis	72.18	1.00e-55	207.00
IUUC-Tca-121158	Theobroma cacao	58.58	5.00e-53	199.00
IUUC-Tre-121973	Trichoderma reesei	56.55	4.00e-43	167.00
IUUC-Tvi-122496	Trichoderma virens	56.21	4.00e-43	167.00
IUUC-Tae-123596	Triticum aestivum	64.86	9.00e-55	206.00
IUUC-Tur-126818	Triticum urartu	63.56	7.00e-41	158.00
IUUC-Tme-127044	Tuber melanosporum	64.75	1.00e-40	158.00
IUUC-Ttr-128548	Tursiops truncatus	75.69	9.00e-67	245.00
IUUC-Vda-129840	Verticillium dahliae	54.44	5.00e-42	163.00
IUUC-Vvi-131685	Vitis vinifera	60.12	3.00e-54	204.00
IUUC-Xtr-132953	Xenopus tropicalis	79.44	7.00e-83	299.00
IUUC-Xma-134093	Xiphophorus maculatus	69.32	1.00e-65	241.00
IUUC-Yli-134548	Yarrowia lipolytica	56.57	1.00e-49	189.00
IUUC-Zma-135182	Zea mays	64.79	5.00e-53	199.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence