iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-106897

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01206132

Gene Name

UBE2E1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000001416.1	ENSSHAT00000001607.1	ENSSHAP00000001590.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	1.80e-50	170.5	2	137

Active Site

Position(s)	Description	Evidence
82	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkee 89
           R++kel++++ dpp+++sa+p+ + +++ew+ +ilGp++++YeggvF l+i+f+++YPfkPPkv+f t+i+h+n++++G +Cl+ilk  
   Q: 2    RIQKELADITLDPPPNCSAGPKGD-NIYEWRSTILGPPGSVYEGGVFFLDITFTPEYPFKPPKVTFRTRIYHCNINSQGVICLDILK-- 87
           9***********************.9************************************************************9.. PP
   S: 90   ekWspalsvesvllsiqsllaepnpesplneeaaellkknreeykkkvre 139
           ++Wspal++++vllsi+sll+++np++pl  ++a+++ +nr+e+++++r+
   Q: 88   DNWSPALTISKVLLSICSLLTDCNPADPLVGSIATQYMTNRAEHDRMARQ 137
           *********************************************99985 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MRIQKELADI TLDPPPNCSA GPKGDNIYEW RSTILGPPGS VYEGGVFFLD ITFTPEYPFK 60
PPKVTFRTRI YHCNINSQGV ICLDILKDNW SPALTISKVL LSICSLLTDC NPADPLVGSI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAAGGCCTG GAGCGCTTTG TCCAGTTAGG AACCTTAGGC CTAAACCCGG GATTTGGGGT 60
AAACAAGTTG GGGGTTGGGA GCGGGGAGAA AGGCCTGATT GGGCGGTTCA AACCTCACCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005634--C:nucleus
GO:0000151--C:ubiquitin ligase complex
GO:0005524--F:ATP binding
GO:0042296--F:ISG15 transferase activity
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0033523--P:histone H2B ubiquitination
GO:0010390--P:histone monoubiquitination
GO:0032020--P:ISG15-protein conjugation
GO:0070936--P:protein K48-linked ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001532	Ailuropoda melanoleuca	100.00	3.00e-84	303.00
IUUC-Apl-004207	Anas platyrhynchos	100.00	1.00e-83	301.00
IUUC-Aca-005103	Anolis carolinensis	100.00	5.00e-84	303.00
IUUC-Ame-011419	Astyanax mexicanus	95.10	3.00e-80	290.00
IUUC-Bta-012796	Bos taurus	93.71	1.00e-77	281.00
IUUC-Cja-019311	Callithrix jacchus	100.00	4.00e-84	303.00
IUUC-Cfa-020017	Canis familiaris	100.00	4.00e-84	303.00
IUUC-Cpo-022266	Cavia porcellus	100.00	4.00e-84	303.00
IUUC-Cre-022791	Chlamydomonas reinhardtii	80.28	9.00e-67	245.00
IUUC-Csa-023538	Chlorocebus sabaeus	100.00	4.00e-84	303.00
IUUC-Cin-025161	Ciona intestinalis	87.41	5.00e-70	256.00
IUUC-Csv-025982	Ciona savignyi	88.11	9.00e-77	278.00
IUUC-Cme-027286	Cyanidioschyzon merolae	78.17	1.00e-65	241.00
IUUC-Dre-027376	Danio rerio	95.77	8.00e-80	289.00
IUUC-Dno-029441	Dasypus novemcinctus	100.00	5.00e-73	265.00
IUUC-Dor-030450	Dipodomys ordii	100.00	3.00e-62	229.00
IUUC-Dme-032042	Drosophila melanogaster	93.01	4.00e-78	283.00
IUUC-Ete-032397	Echinops telfairi	100.00	2.00e-84	304.00
IUUC-Eca-033613	Equus caballus	100.00	3.00e-83	300.00
IUUC-Eeu-035232	Erinaceus europaeus	95.77	7.00e-80	288.00
IUUC-Fca-035467	Felis catus	100.00	4.00e-84	303.00
IUUC-Fal-036907	Ficedula albicollis	100.00	5.00e-84	303.00
IUUC-Gmo-039645	Gadus morhua	95.10	6.00e-81	293.00
IUUC-Gga-040403	Gallus gallus	100.00	5.00e-84	303.00
IUUC-Gac-041661	Gasterosteus aculeatus	95.10	9.00e-81	292.00
IUUC-Ggo-045507	Gorilla gorilla	100.00	4.00e-84	303.00
IUUC-Hsa-046576	Homo sapiens	100.00	4.00e-84	303.00
IUUC-Itr-048197	Ictidomys tridecemlineatus	100.00	5.00e-73	265.00
IUUC-Lch-050322	Latimeria chalumnae	97.90	4.00e-83	300.00
IUUC-Loc-052673	Lepisosteus oculatus	97.20	3.00e-82	297.00
IUUC-Laf-054313	Loxodonta africana	100.00	4.00e-84	303.00
IUUC-Mcc-055072	Macaca mulatta	97.90	3.00e-82	297.00
IUUC-Meu-056590	Macropus eugenii	100.00	1.00e-82	297.00
IUUC-Mga-059436	Meleagris gallopavo	95.80	1.00e-80	292.00
IUUC-Mmr-060791	Microcebus murinus	100.00	4.00e-84	303.00
IUUC-Mdo-062348	Monodelphis domestica	98.61	7.00e-84	302.00
IUUC-Mmu-063297	Mus musculus	100.00	1.00e-84	305.00
IUUC-Mpu-065698	Mustela putorius furo	100.00	1.00e-84	305.00
IUUC-Mlu-067897	Myotis lucifugus	97.90	3.00e-82	297.00
IUUC-Nle-069622	Nomascus leucogenys	100.00	4.00e-84	303.00
IUUC-Opr-070917	Ochotona princeps	92.66	1.00e-55	207.00
IUUC-Ont-072384	Oreochromis niloticus	95.80	1.00e-81	295.00
IUUC-Oan-073006	Ornithorhynchus anatinus	100.00	5.00e-73	265.00
IUUC-Ocu-074055	Oryctolagus cuniculus	100.00	4.00e-84	303.00
IUUC-Ola-086636	Oryzias latipes	96.50	7.00e-81	292.00
IUUC-Olu-087783	Ostreococcus lucimarinus	76.26	8.00e-63	231.00
IUUC-Oga-088863	Otolemur garnettii	100.00	4.00e-84	303.00
IUUC-Oar-089803	Ovis aries	100.00	1.00e-84	305.00
IUUC-Ptr-090914	Pan troglodytes	100.00	4.00e-84	303.00
IUUC-Pan-092786	Papio anubis	100.00	4.00e-84	303.00
IUUC-Psi-093923	Pelodiscus sinensis	100.00	5.00e-84	303.00
IUUC-Pma-094642	Petromyzon marinus	95.24	1.00e-69	254.00
IUUC-Ppa-095789	Physcomitrella patens	77.46	4.00e-65	239.00
IUUC-Pfo-096966	Poecilia formosa	96.50	8.00e-81	292.00
IUUC-Pab-098614	Pongo abelii	100.00	4.00e-84	303.00
IUUC-Pop-099024	Populus trichocarpa	61.97	3.00e-54	204.00
IUUC-Pca-100467	Procavia capensis	95.80	1.00e-80	292.00
IUUC-Pva-102561	Pteropus vampyrus	97.90	3.00e-82	297.00
IUUC-Rno-105518	Rattus norvegicus	100.00	1.00e-84	304.00
IUUC-Smo-109298	Selaginella moellendorffii	68.31	1.00e-57	214.00
IUUC-Sar-113672	Sorex araneus	95.80	1.00e-80	292.00
IUUC-Ssc-116298	Sus scrofa	100.00	3.00e-83	300.00
IUUC-Tgu-116958	Taeniopygia guttata	100.00	1.00e-83	301.00
IUUC-Tru-118527	Takifugu rubripes	95.07	3.00e-79	286.00
IUUC-Tsy-119046	Tarsius syrichta	95.80	2.00e-80	291.00
IUUC-Tni-120349	Tetraodon nigroviridis	95.80	8.00e-80	289.00
IUUC-Tbe-127690	Tupaia belangeri	95.80	1.00e-80	291.00
IUUC-Ttr-128358	Tursiops truncatus	97.90	3.00e-82	297.00
IUUC-Vpa-130232	Vicugna pacos	96.45	5.00e-78	283.00
IUUC-Xtr-132547	Xenopus tropicalis	100.00	2.00e-83	301.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence