iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033856

UUCD1 version

UUC-EqC-00237

Ensembl Protein ID

ENSECAP00000020762.1

UniProt Accession

F6TRD6; F6TRD6_HORSE

Protein Name

Uncharacterized protein

Gene Name

KLHL17

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000023217.1	ENSECAT00000024971.1	ENSECAP00000020762.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	4.30e-19	68.8	57	120
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	6.00e-11	41.5	155	185

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkld 66
           +D++l+v+ +e++ahk+vLa++S++F+a+f ++++es+ +  v+++d++p+++ +l++F Yt ++ 
   Q: 57   CDIVLHVAAKEIRAHKVVLASCSPYFHAMF-TQMSESR-QTHVTLHDIDPQALDQLVQFAYTAEIV 120
           8*****************************.67****9.***********************9986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           ++N lgi+ fAd+++c+dL +aa++++l+hF
   Q: 155  PSNWLGIRGFADTHSCSDLLKAAHRYVLQHF 185
           6788*************************** PP

Organism

Equus caballus

Protein Sequence
(Fasta)

SPEAERARPR QARPTAPMEG AVQLLSREGH TVSHNSKRHY HDAFVAMSRM RQRGLLCDIV 60
LHVAAKEIRA HKVVLASCSP YFHAMFTQMS ESRQTHVTLH DIDPQALDQL VQFAYTAEIV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGCCCAGAGG CAGAGCGTGC ACGTCCGCGG CAGGCCCGGC CCACTGCCCC CATGGAGGGT 60
GCAGTGCAGC TGCTGAGCCG CGAGGGCCAC ACTGTGTCCC ACAACTCCAA GCGGCACTAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR011043--Gal_Oxase/kelch_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0032839--C:dendrite cytoplasm
GO:0005615--C:extracellular space
GO:0051015--F:actin filament binding
GO:0030036--P:actin cytoskeleton organization
GO:0007420--P:brain development
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002095	Ailuropoda melanoleuca	98.61	0.00e+00	1117.00
IUUC-Apl-003315	Anas platyrhynchos	78.81	0.00e+00	916.00
IUUC-Aca-005317	Anolis carolinensis	89.34	0.00e+00	1057.00
IUUC-Ame-010707	Astyanax mexicanus	89.22	0.00e+00	1036.00
IUUC-Bta-012531	Bos taurus	97.91	0.00e+00	1109.00
IUUC-Cfa-021138	Canis familiaris	98.61	0.00e+00	1116.00
IUUC-Cpo-021432	Cavia porcellus	97.04	0.00e+00	1145.00
IUUC-Csa-023772	Chlorocebus sabaeus	97.22	0.00e+00	1123.00
IUUC-Dre-028401	Danio rerio	89.22	0.00e+00	1038.00
IUUC-Dno-029729	Dasypus novemcinctus	95.65	0.00e+00	1078.00
IUUC-Dor-030659	Dipodomys ordii	96.70	0.00e+00	1097.00
IUUC-Dme-031996	Drosophila melanogaster	55.99	0.00e+00	630.00
IUUC-Ete-033128	Echinops telfairi	92.24	0.00e+00	846.00
IUUC-Eeu-034646	Erinaceus europaeus	92.37	0.00e+00	1030.00
IUUC-Fca-036183	Felis catus	98.09	0.00e+00	1108.00
IUUC-Fal-037046	Ficedula albicollis	79.96	0.00e+00	842.00
IUUC-Gmo-039526	Gadus morhua	82.73	0.00e+00	943.00
IUUC-Gga-040510	Gallus gallus	90.64	0.00e+00	1054.00
IUUC-Gac-042529	Gasterosteus aculeatus	86.43	0.00e+00	1024.00
IUUC-Ggo-044992	Gorilla gorilla	97.22	0.00e+00	1148.00
IUUC-Hsa-046621	Homo sapiens	97.22	0.00e+00	1148.00
IUUC-Itr-048791	Ictidomys tridecemlineatus	97.91	0.00e+00	1110.00
IUUC-Lch-049449	Latimeria chalumnae	89.39	0.00e+00	1042.00
IUUC-Loc-052690	Lepisosteus oculatus	83.98	0.00e+00	1030.00
IUUC-Laf-053925	Loxodonta africana	96.29	0.00e+00	699.00
IUUC-Mcc-054780	Macaca mulatta	89.39	0.00e+00	1026.00
IUUC-Meu-056812	Macropus eugenii	84.13	0.00e+00	811.00
IUUC-Mpo-057526	Magnaporthe poae	27.50	1.00e-05	43.10
IUUC-Mga-059704	Meleagris gallopavo	90.16	0.00e+00	1053.00
IUUC-Mmr-061724	Microcebus murinus	97.57	0.00e+00	1106.00
IUUC-Mmu-063886	Mus musculus	97.57	0.00e+00	1106.00
IUUC-Mpu-066774	Mustela putorius furo	98.61	0.00e+00	1117.00
IUUC-Nle-070159	Nomascus leucogenys	97.22	0.00e+00	1147.00
IUUC-Opr-070367	Ochotona princeps	89.89	0.00e+00	808.00
IUUC-Ont-071757	Oreochromis niloticus	88.35	0.00e+00	1028.00
IUUC-Ocu-074674	Oryctolagus cuniculus	89.65	0.00e+00	997.00
IUUC-Ola-086760	Oryzias latipes	86.61	0.00e+00	1026.00
IUUC-Oga-088570	Otolemur garnettii	96.87	0.00e+00	1100.00
IUUC-Oar-090344	Ovis aries	88.21	0.00e+00	964.00
IUUC-Ptr-090946	Pan troglodytes	97.04	0.00e+00	1147.00
IUUC-Pan-092661	Papio anubis	97.22	0.00e+00	1123.00
IUUC-Psi-094009	Pelodiscus sinensis	87.37	0.00e+00	1021.00
IUUC-Pfo-097164	Poecilia formosa	83.06	0.00e+00	1020.00
IUUC-Pab-097554	Pongo abelii	77.78	0.00e+00	729.00
IUUC-Pca-100460	Procavia capensis	86.43	0.00e+00	994.00
IUUC-Pva-102180	Pteropus vampyrus	98.09	0.00e+00	1109.00
IUUC-Rno-105907	Rattus norvegicus	97.57	0.00e+00	1106.00
IUUC-Sar-113112	Sorex araneus	83.08	1.00e-179	622.00
IUUC-Ssc-115448	Sus scrofa	90.77	0.00e+00	815.00
IUUC-Tgu-117293	Taeniopygia guttata	90.53	0.00e+00	1058.00
IUUC-Tru-117814	Takifugu rubripes	86.66	0.00e+00	1007.00
IUUC-Tni-120531	Tetraodon nigroviridis	88.35	0.00e+00	1029.00
IUUC-Tca-120913	Theobroma cacao	35.19	1.00e-36	147.00
IUUC-Tae-124075	Triticum aestivum	35.36	8.00e-42	165.00
IUUC-Tbe-127460	Tupaia belangeri	98.00	0.00e+00	1059.00
IUUC-Ttr-129301	Tursiops truncatus	96.79	1.00e-135	476.00
IUUC-Xtr-132356	Xenopus tropicalis	90.61	0.00e+00	1050.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence