iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-044620

UUCD1 version

UUC-GoG-00964

Ensembl Protein ID

ENSGGOP00000027797.1

UniProt Accession

G3SI57; G3SI57_GORGO

Protein Name

Uncharacterized protein

Gene Name

KLHL2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000001786.2	ENSGGOT00000001798.2	ENSGGOP00000001760.2
ENSGGOG00000001786.2	ENSGGOT00000034516.1	ENSGGOP00000027797.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	2.70e-12	47.3	56	102
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	9.70e-11	40.8	156	185

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveik.d 47
           +Dv++v ++ e++ah++vLaa+S++F+a+f+ +   ++ k+ v+i+ d
   Q: 56   CDVTIVAEDMEISAHRVVLAACSPYFHAMFTVKIMPKN-KKVVVIRvD 102
           8**********************************887.999999953 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkhF 31
            Nclgi++fAd++ c+dL  +a++++++hF
   Q: 156  VNCLGIRAFADMHACTDLLNKANTYAEQHF 185
           6****************************9 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

FDGTLTPGRC TKQGHQKPLD SKDDNTEKHC PVTVNPWHMK KAFKVMNELR SQNLLCDVTI 60
VAEDMEISAH RVVLAACSPY FHAMFTVKIM PKNKKVVVIR VDDKWNLQIQ VDRSYIARIS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTATGGT TGGAAGCACG GCCCCAGATT CTCTTTGTGT AGGTGTCTGT TTATTAATTC 60
ATTCAATGTG CAAATATTTG AATGCCTATC TCTGCCTGGC ACTGTGCGTG GTGCTTTTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015916--Gal_Oxidase_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002378	Ailuropoda melanoleuca	94.04	0.00e+00	1102.00
IUUC-Apl-003260	Anas platyrhynchos	88.18	0.00e+00	1038.00
IUUC-Aca-005143	Anolis carolinensis	84.21	0.00e+00	1038.00
IUUC-Cja-018942	Callithrix jacchus	94.69	0.00e+00	1107.00
IUUC-Cfa-020886	Canis familiaris	94.70	0.00e+00	1110.00
IUUC-Cpo-022543	Cavia porcellus	94.55	0.00e+00	1112.00
IUUC-Csa-023088	Chlorocebus sabaeus	94.21	0.00e+00	1107.00
IUUC-Dre-028082	Danio rerio	77.57	0.00e+00	920.00
IUUC-Dno-029873	Dasypus novemcinctus	92.19	0.00e+00	1083.00
IUUC-Dor-030460	Dipodomys ordii	73.97	0.00e+00	793.00
IUUC-Eca-033798	Equus caballus	94.01	0.00e+00	1102.00
IUUC-Eeu-034824	Erinaceus europaeus	91.53	0.00e+00	971.00
IUUC-Fca-036455	Felis catus	94.70	0.00e+00	1110.00
IUUC-Fal-037293	Ficedula albicollis	87.57	0.00e+00	980.00
IUUC-Gmo-038811	Gadus morhua	74.48	0.00e+00	821.00
IUUC-Gga-040805	Gallus gallus	88.03	0.00e+00	1040.00
IUUC-Gac-041979	Gasterosteus aculeatus	77.45	0.00e+00	828.00
IUUC-Hsa-046265	Homo sapiens	94.55	0.00e+00	1110.00
IUUC-Lch-049939	Latimeria chalumnae	79.45	0.00e+00	916.00
IUUC-Loc-052780	Lepisosteus oculatus	82.36	0.00e+00	973.00
IUUC-Laf-053800	Loxodonta africana	94.18	0.00e+00	1103.00
IUUC-Mcc-055732	Macaca mulatta	93.49	0.00e+00	1094.00
IUUC-Meu-056011	Macropus eugenii	90.59	0.00e+00	988.00
IUUC-Mmr-061067	Microcebus murinus	92.82	0.00e+00	1087.00
IUUC-Mdo-062977	Monodelphis domestica	89.98	0.00e+00	1071.00
IUUC-Mmu-064035	Mus musculus	93.61	0.00e+00	1086.00
IUUC-Mpu-066726	Mustela putorius furo	94.53	0.00e+00	1108.00
IUUC-Mlu-067020	Myotis lucifugus	93.76	0.00e+00	1115.00
IUUC-Nle-069456	Nomascus leucogenys	94.70	0.00e+00	1110.00
IUUC-Opr-071130	Ochotona princeps	84.25	0.00e+00	959.00
IUUC-Ont-072219	Oreochromis niloticus	77.68	0.00e+00	878.00
IUUC-Oan-073699	Ornithorhynchus anatinus	90.60	0.00e+00	903.00
IUUC-Ocu-074045	Oryctolagus cuniculus	93.87	0.00e+00	1104.00
IUUC-Oga-088494	Otolemur garnettii	94.02	0.00e+00	1104.00
IUUC-Oar-089645	Ovis aries	94.01	0.00e+00	1100.00
IUUC-Ptr-091063	Pan troglodytes	94.55	0.00e+00	1110.00
IUUC-Pan-092273	Papio anubis	92.98	0.00e+00	893.00
IUUC-Psi-093946	Pelodiscus sinensis	87.05	0.00e+00	1046.00
IUUC-Pfo-096817	Poecilia formosa	77.09	0.00e+00	890.00
IUUC-Pab-097768	Pongo abelii	94.38	0.00e+00	1108.00
IUUC-Pca-100607	Procavia capensis	76.98	0.00e+00	773.00
IUUC-Pva-102218	Pteropus vampyrus	88.25	0.00e+00	1022.00
IUUC-Rno-105250	Rattus norvegicus	93.53	0.00e+00	1099.00
IUUC-Sar-113249	Sorex araneus	93.57	0.00e+00	1080.00
IUUC-Ssc-115423	Sus scrofa	94.19	0.00e+00	1104.00
IUUC-Tgu-117050	Taeniopygia guttata	86.67	0.00e+00	1023.00
IUUC-Tru-118239	Takifugu rubripes	76.65	0.00e+00	920.00
IUUC-Tsy-119377	Tarsius syrichta	80.14	0.00e+00	942.00
IUUC-Tni-120122	Tetraodon nigroviridis	76.67	0.00e+00	823.00
IUUC-Ttr-128574	Tursiops truncatus	82.11	0.00e+00	946.00
IUUC-Vpa-130707	Vicugna pacos	95.28	0.00e+00	878.00
IUUC-Xtr-132035	Xenopus tropicalis	82.45	0.00e+00	995.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence