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Tag Content
UUCD2 ID IUUC-Oga-089010
UUCD1 version UUC-OtG-00656
Ensembl Protein ID ENSOGAP00000015001.2
UniProt Accession H0XG24; H0XG24_OTOGA
Genbank Protein ID ENSOGAP00000015001
Protein Name Uncharacterized protein
Genbank Nucleotide ID AAQR03180368
Gene Name PRPF19
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSOGAG00000016756.2 ENSOGAT00000016762.2 ENSOGAP00000015001.2
ENSOGAG00000016756.2 ENSOGAT00000027673.1 ENSOGAP00000017714.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 2.90e-32 109.3 392 425
E3 activity/RING/U-box 7.30e-13 48.4 7 65
UBD/Beta-Prp 5.10e-54 183.4 233 463
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlrt 32
           gH++++t++af  ++ +l++++dD ++k+WDlr+
   Q: 392  GHSGPITSIAFseNGYYLATAADDSSVKLWDLRK 425
           8**********976699**************986 PP
   

   E3 activity/RING/U-box
   S: 9    pIslelMrdPvvlp.sGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqa 67
           ++s+e++++P+v+p s+++y+r+ Iek++a++g+ +P+++qpl+ee+l++ ++ + +  +
   Q: 7    TVSNEVPEHPCVSPvSNHVYERRLIEKYIAENGT-DPINNQPLSEEQLIDIKVAHPIRPK 65
           689******************************9.***************9998877665 PP
   

   UBD/Beta-Prp
   S: 19   spdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgd 107
             d++ ++tg++d+ + v+d ++++ l++l+gh+++vt+v f+p++++  ++s D+ti++w++ + +cv+++++he+ v+ ls++++gd
   Q: 233  PSDTNKILTGGADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPSQDLVFSASPDATIRIWSVPNASCVQVVRAHESAVTGLSLHATGD 321
           568899*********************************************************************************** PP
   S: 108  klvsGshdrtirvwdletgqclee.tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkel 195
           +l+s s+d++    d++tg +l + t++    + +c+++hpdg ++ +G+ D+++++Wdlk  + +  + g h ++++s++f++ng +l
   Q: 322  YLLSSSDDQYWAFSDIQTGRVLTKvTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPG-HSGPITSIAFSENGYYL 409
           **********************997777777789************************************9.***************** PP
   S: 196  vsgsldgtvklwdlqtgecvrtlnghtd.nvksvrfspnderlvsgssDgsiri 248
           +++++d++vklwdl++ +  +tl+  ++  vks+ f++ +++l+ g+ D +i+i
   Q: 410  ATAADDSSVKLWDLRKLKNFKTLQLENNfEVKSLIFDQSGTYLALGGTDVQIYI 463
           ***************999999999877626*******************99987 PP
   
Organism Otolemur garnettii
Protein Sequence
(Fasta)
MACLFSTVSN EVPEHPCVSP VSNHVYERRL IEKYIAENGT DPINNQPLSE EQLIDIKVAH 60
PIRPKPPSAT SIPAILKALQ DEWDAVMLHS FTLRQQLQTT RQELSHALYQ HDAACRVIAR 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Oga-089010|E3,WD_repeat;E3,U-box;UBD,Beta-Prp|Otolemur garnettii
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CCCACGTGAA GCGCTACGCT ATCTTCGTTC GGCGGGGCTG CTGCCAGCTC GCCGCGGAGA 60
GTCGCGGCAG CAGCCAGGGA CCGGAAGTGG CTCGCGGAGA TTCAGAAGCT GGTCCCGGAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Oga-089010|E3,WD_repeat;E3,U-box;UBD,Beta-Prp|Otolemur garnettii
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat
Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR013915--Pre-mRNA_splic_Prp19
IPR000772--Ricin_B_lectin
IPR003613--Ubox_domain
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS50231--RICIN_B_LECTIN
PS51698--U_BOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF08606--Prp19
PF04564--U-box
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00504--Ubox
SM00320--WD40
Gene Ontology

GO:0071013--C:catalytic step 2 spliceosome
GO:0005737--C:cytoplasm
GO:0005662--C:DNA replication factor A complex
GO:0005811--C:lipid particle
GO:0016020--C:membrane
GO:0016607--C:nuclear speck
GO:0000974--C:Prp19 complex
GO:0035861--C:site of double-strand break
GO:0034450--F:ubiquitin-ubiquitin ligase activity
GO:0034613--P:cellular protein localization
GO:0006303--P:double-strand break repair via nonhomologous end joining
GO:0001833--P:inner cell mass cell proliferation
GO:0008610--P:lipid biosynthetic process
GO:0045665--P:negative regulation of neuron differentiation
GO:0048711--P:positive regulation of astrocyte differentiation
GO:0048026--P:positive regulation of mRNA splicing, via spliceosome
GO:0010498--P:proteasomal protein catabolic process
GO:0070534--P:protein K63-linked ubiquitination
GO:0072422--P:signal transduction involved in DNA damage checkpoint
GO:0000245--P:spliceosomal complex assembly
GO:0000244--P:spliceosomal tri-snRNP complex assembly
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000488 Aegilops tauschii 38.34 7.00e-92 332.00
IUUC-Aml-001230 Ailuropoda melanoleuca 95.57 0.00e+00 953.00
IUUC-Atr-002594 Amborella trichopoda 43.15 9.00e-114 403.00
IUUC-Apl-003686 Anas platyrhynchos 83.37 0.00e+00 689.00
IUUC-Aca-005272 Anolis carolinensis 93.10 0.00e+00 950.00
IUUC-Aly-005586 Arabidopsis lyrata 42.83 2.00e-113 402.00
IUUC-Ath-007696 Arabidopsis thaliana 42.48 6.00e-110 391.00
IUUC-Acl-008335 Aspergillus clavatus 35.99 1.00e-65 243.00
IUUC-Afl-008527 Aspergillus flavus 37.53 4.00e-68 251.00
IUUC-Afu-008957 Aspergillus fumigatus 36.60 4.00e-75 275.00
IUUC-Ani-009280 Aspergillus nidulans 36.69 2.00e-63 236.00
IUUC-Ang-009746 Aspergillus niger 36.27 2.00e-63 236.00
IUUC-Aor-009905 Aspergillus oryzae 37.32 1.00e-71 263.00
IUUC-Ate-010412 Aspergillus terreus 37.32 4.00e-62 232.00
IUUC-Ame-011561 Astyanax mexicanus 79.17 2.00e-98 352.00
IUUC-Bgr-012283 Blumeria graminis 33.20 1.00e-55 210.00
IUUC-Bta-013242 Bos taurus 95.07 0.00e+00 962.00
IUUC-Bci-013901 Botrytis cinerea 32.75 2.00e-60 226.00
IUUC-Bdi-014277 Brachypodium distachyon 42.21 3.00e-116 411.00
IUUC-Bol-016207 Brassica oleracea 43.81 7.00e-113 400.00
IUUC-Bra-017650 Brassica rapa 42.91 2.00e-110 392.00
IUUC-Cel-018271 Caenorhabditis elegans 49.90 6.00e-142 497.00
IUUC-Cja-019879 Callithrix jacchus 94.88 0.00e+00 957.00
IUUC-Cfa-020175 Canis familiaris 94.67 0.00e+00 960.00
IUUC-Cpo-022379 Cavia porcellus 94.67 0.00e+00 960.00
IUUC-Cre-022993 Chlamydomonas reinhardtii 39.88 2.00e-97 349.00
IUUC-Csa-023500 Chlorocebus sabaeus 95.27 0.00e+00 964.00
IUUC-Cho-025065 Choloepus hoffmanni 81.21 4.00e-134 470.00
IUUC-Cin-025699 Ciona intestinalis 67.81 1.00e-170 592.00
IUUC-Csv-026128 Ciona savignyi 64.93 0.00e+00 662.00
IUUC-Cgl-026507 Colletotrichum gloeosporioides 29.55 9.00e-47 181.00
IUUC-Cne-026860 Cryptococcus neoformans 37.19 2.00e-90 326.00
IUUC-Dre-028187 Danio rerio 82.18 0.00e+00 818.00
IUUC-Dno-029453 Dasypus novemcinctus 95.07 0.00e+00 962.00
IUUC-Dor-030150 Dipodomys ordii 91.36 3.00e-116 412.00
IUUC-Dse-031220 Dothistroma septosporum 32.01 6.00e-56 211.00
IUUC-Dme-031906 Drosophila melanogaster 64.48 0.00e+00 634.00
IUUC-Ete-033035 Echinops telfairi 98.25 6.00e-136 477.00
IUUC-Eca-033478 Equus caballus 94.87 0.00e+00 960.00
IUUC-Eeu-034974 Erinaceus europaeus 93.71 0.00e+00 639.00
IUUC-Fca-036194 Felis catus 95.46 0.00e+00 966.00
IUUC-Fal-037417 Ficedula albicollis 92.70 0.00e+00 946.00
IUUC-Fox-037922 Fusarium oxysporum 32.61 8.00e-60 224.00
IUUC-Fso-038256 Fusarium solani 34.61 7.00e-62 231.00
IUUC-Gmo-038713 Gadus morhua 83.37 0.00e+00 834.00
IUUC-Ggr-039854 Gaeumannomyces graminis 32.12 1.00e-51 197.00
IUUC-Gga-041143 Gallus gallus 93.10 0.00e+00 949.00
IUUC-Gac-042129 Gasterosteus aculeatus 82.18 0.00e+00 849.00
IUUC-Gma-044273 Glycine max 44.11 9.00e-115 407.00
IUUC-Ggo-045262 Gorilla gorilla 95.27 0.00e+00 964.00
IUUC-Hsa-046036 Homo sapiens 95.27 0.00e+00 964.00
IUUC-Hvu-047442 Hordeum vulgare 40.00 7.00e-61 227.00
IUUC-Itr-048169 Ictidomys tridecemlineatus 94.67 0.00e+00 919.00
IUUC-Lch-050105 Latimeria chalumnae 86.39 0.00e+00 892.00
IUUC-Lpe-050976 Leersia perrieri 43.24 2.00e-113 402.00
IUUC-Loc-052042 Lepisosteus oculatus 73.04 0.00e+00 662.00
IUUC-Lma-053143 Leptosphaeria maculans 33.47 6.00e-60 226.00
IUUC-Laf-053451 Loxodonta africana 91.79 0.00e+00 952.00
IUUC-Mcc-055786 Macaca mulatta 95.27 0.00e+00 964.00
IUUC-Meu-056161 Macropus eugenii 91.46 6.00e-129 454.00
IUUC-Mor-057215 Magnaporthe oryzae 32.02 4.00e-51 195.00
IUUC-Mpo-057419 Magnaporthe poae 31.15 2.00e-48 186.00
IUUC-Mtr-057756 Medicago truncatula 43.00 9.00e-111 394.00
IUUC-Mla-059085 Melampsora laricipopulina 38.21 8.00e-84 304.00
IUUC-Mga-060158 Meleagris gallopavo 86.90 0.00e+00 844.00
IUUC-Mvi-060441 Microbotryum violaceum 37.43 3.00e-76 279.00
IUUC-Mmr-061085 Microcebus murinus 95.27 0.00e+00 964.00
IUUC-Mdo-061804 Monodelphis domestica 94.87 0.00e+00 961.00
IUUC-Mmu-063608 Mus musculus 91.25 0.00e+00 946.00
IUUC-Mac-064972 Musa acuminata 42.86 4.00e-110 391.00
IUUC-Mpu-065700 Mustela putorius furo 94.67 0.00e+00 959.00
IUUC-Mlu-068223 Myotis lucifugus 90.61 0.00e+00 938.00
IUUC-Nfi-068504 Neosartorya fischeri 36.60 4.00e-75 275.00
IUUC-Ncr-068729 Neurospora crassa 36.10 6.00e-60 224.00
IUUC-Nle-069754 Nomascus leucogenys 95.27 0.00e+00 964.00
IUUC-Opr-070621 Ochotona princeps 91.83 0.00e+00 910.00
IUUC-Ont-071377 Oreochromis niloticus 82.38 0.00e+00 829.00
IUUC-Oan-073498 Ornithorhynchus anatinus 68.37 2.00e-111 394.00
IUUC-Ocu-074182 Oryctolagus cuniculus 91.48 0.00e+00 951.00
IUUC-Oba-075509 Oryza barthii 42.40 5.00e-115 408.00
IUUC-Obr-076480 Oryza brachyantha 43.49 4.00e-116 411.00
IUUC-Ogl-077052 Oryza glaberrima 42.40 5.00e-115 407.00
IUUC-Ogu-078919 Oryza glumaepatula 42.40 5.00e-115 408.00
IUUC-Oin-079357 Oryza indica 41.68 6.00e-108 384.00
IUUC-Olo-080376 Oryza longistaminata 42.62 2.00e-104 372.00
IUUC-Ome-081973 Oryza meridionalis 42.19 6.00e-105 374.00
IUUC-Oni-082849 Oryza nivara 42.59 1.00e-115 410.00
IUUC-Opu-083243 Oryza punctata 42.21 2.00e-114 405.00
IUUC-Oru-084613 Oryza rufipogon 42.67 6.00e-115 407.00
IUUC-Osa-085407 Oryza sativa 42.37 2.00e-114 405.00
IUUC-Ola-086566 Oryzias latipes 81.18 0.00e+00 817.00
IUUC-Olu-087757 Ostreococcus lucimarinus 38.84 3.00e-92 332.00
IUUC-Oar-089638 Ovis aries 95.07 0.00e+00 962.00
IUUC-Ptr-091141 Pan troglodytes 95.27 0.00e+00 964.00
IUUC-Pan-092662 Papio anubis 95.27 0.00e+00 964.00
IUUC-Psi-093777 Pelodiscus sinensis 92.69 0.00e+00 781.00
IUUC-Pno-095115 Phaeosphaeria nodorum 33.47 2.00e-59 223.00
IUUC-Ppa-095841 Physcomitrella patens 42.83 1.00e-113 403.00
IUUC-Pfo-096390 Poecilia formosa 81.19 0.00e+00 826.00
IUUC-Pab-098250 Pongo abelii 93.44 0.00e+00 896.00
IUUC-Pop-099854 Populus trichocarpa 43.26 6.00e-115 407.00
IUUC-Pca-100553 Procavia capensis 94.67 0.00e+00 955.00
IUUC-Ppe-101383 Prunus persica 42.86 4.00e-109 388.00
IUUC-Pva-102189 Pteropus vampyrus 94.87 0.00e+00 961.00
IUUC-Pgr-103304 Puccinia graminis 36.47 2.00e-80 293.00
IUUC-Ptt-103984 Puccinia triticina 36.89 9.00e-86 310.00
IUUC-Pte-104385 Pyrenophora teres 32.91 1.00e-64 240.00
IUUC-Pyt-104697 Pyrenophora triticirepentis 33.26 4.00e-66 245.00
IUUC-Rno-105581 Rattus norvegicus 94.67 0.00e+00 959.00
IUUC-Sha-107071 Sarcophilus harrisii 90.93 0.00e+00 947.00
IUUC-Sja-107697 Schizosaccharomyces japonicus 30.21 2.00e-34 140.00
IUUC-Spo-108315 Schizosaccharomyces pombe 32.02 9.00e-44 171.00
IUUC-Ssl-108628 Sclerotinia sclerotiorum 34.65 2.00e-59 223.00
IUUC-Smo-109648 Selaginella moellendorffii 43.33 6.00e-116 410.00
IUUC-Sit-109873 Setaria italica 42.31 7.00e-113 401.00
IUUC-Sly-111673 Solanum lycopersicum 44.19 3.00e-108 385.00
IUUC-Stu-112125 Solanum tuberosum 43.81 5.00e-107 381.00
IUUC-Sbi-114696 Sorghum bicolor 41.94 2.00e-107 382.00
IUUC-Sre-115134 Sporisorium reilianum 31.12 4.00e-69 255.00
IUUC-Ssc-116260 Sus scrofa 94.87 0.00e+00 961.00
IUUC-Tgu-116533 Taeniopygia guttata 93.10 0.00e+00 949.00
IUUC-Tru-117800 Takifugu rubripes 81.58 0.00e+00 852.00
IUUC-Tsy-118980 Tarsius syrichta 90.10 0.00e+00 880.00
IUUC-Tni-120334 Tetraodon nigroviridis 76.81 2.00e-163 568.00
IUUC-Tca-121807 Theobroma cacao 42.26 5.00e-114 404.00
IUUC-Tre-121920 Trichoderma reesei 33.20 4.00e-60 225.00
IUUC-Tvi-122294 Trichoderma virens 32.56 6.00e-51 195.00
IUUC-Tae-125794 Triticum aestivum 43.10 5.00e-117 414.00
IUUC-Tur-126664 Triticum urartu 39.19 1.00e-111 396.00
IUUC-Tme-127026 Tuber melanosporum 33.80 9.00e-66 244.00
IUUC-Tbe-127582 Tupaia belangeri 94.01 0.00e+00 639.00
IUUC-Ttr-128313 Tursiops truncatus 94.67 0.00e+00 952.00
IUUC-Uma-129626 Ustilago maydis 33.71 5.00e-73 268.00
IUUC-Vda-129699 Verticillium dahliae 35.20 1.00e-63 236.00
IUUC-Vpa-130593 Vicugna pacos 94.77 0.00e+00 860.00
IUUC-Vvi-131668 Vitis vinifera 42.91 2.00e-114 405.00
IUUC-Xtr-132186 Xenopus tropicalis 81.45 0.00e+00 725.00
IUUC-Xma-133212 Xiphophorus maculatus 80.99 0.00e+00 820.00
IUUC-Yli-134607 Yarrowia lipolytica 54.55 5.00e-39 152.00
IUUC-Zma-135662 Zea mays 43.43 1.00e-114 406.00
Created Date 25-Jun-2017

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