iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gac-041557

UUCD1 version

UUC-GaA-01252

Ensembl Protein ID

ENSGACP00000003354.1

UniProt Accession

G3NDF4; G3NDF4_GASAC

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000002557.1	ENSGACT00000003365.1	ENSGACP00000003354.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.60e-83	280.4	316	939
UBD/Alpha-Helix/UIM	1.20e-07	31.3	796	813
UBD/Alpha-Helix/UIM	0.00013	13.0	697	714

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaeefsgy 87
           +G++NlgNtCYmN++LQ+L+++p++ +++l+   +++++++   p ++ll+ +++l+ +      ++k+   r++++a++++ae+fsg+
   Q: 316  QGFSNLGNTCYMNAILQSLFSLPSFSSDMLR---QSIPWKK--LPINALLRRFAHLMVKKDvgCPETKKDLLRKVKSAISSTAERFSGN 399
           69*****************************...9***984..46666666666666555467788889999***************** PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.................aeekkkkknkslisdlFqgqlksqikclec 159
           +q+Da+Efl+++ldql+++++k +++ ++e+  +++s+ + e                  e ++ + +++++  +++++++++i+c+ c
   Q: 400  MQNDAHEFLSQCLDQLKDDVEKMNKSWTNEAAASSTSSVPCEgvpdatstsppakaelgDEADTSRIYTCPVAVNMEFEVQHTITCKGC 488
           ********************774444444444444444444499*************998899999999******************** PP
   S: 160  dnvssreepfldlslpvpgkeetkke.slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksre 247
           ++v +++e+f+dls+++p++++t ++ s+qd+L+ f++ ee+e    y+cekc++k+ a+ ++k++klP+vLilhLkR+sf+ + ++++
   Q: 489  GEVVTKREQFNDLSIDLPRRKKTLPLrSIQDSLDLFFRVEEIE----YSCEKCNGKS-ATVMHKFSKLPRVLILHLKRYSFNAQLSMNS 572
           ******************999887645***************9....********99.9****************************** PP
   S: 248  kinkkvefpleLdlspfcts..................................................................... 267
           k+ ++v +p+ L+l ++ct+                                                                     
   Q: 573  KLGQQVVIPRYLTLLSHCTEstrpplslgwssqtsmsrtlktsqlvnsstaplrrigakvatstsilldsdceeelsrkvnmsrkrrls 661
           ********************999999999999999999999999999999999999999999999999999999999999999999999 PP
   S: 268  ......................................................................................... 267
                                                                                                    
   Q: 662  scppddddrpeefrhgpvcpqrgatidsadfgginddemlaavlemsrqeaglsapplpenepssspdtgfgdtdahdmayhtdllete 750
           99999999999999999999999999999999999999999999888888888888888888888888888888888888888888888 PP
   S: 268  ...............................................peekqke................................... 274
                                                          +     e                                   
   Q: 751  skppsevldsldltmdenkenqtpdsvqqqgeldwvqqysldqereeQ-----Elqqalaqslqeheaqelredddlkratelslqefn 834
           888888888888877777766666666666666666666666555550.....055555555555666666666666666666666677 PP
   S: 275  ........................................kkkYeLiavvvHsG.slssGHYvayvknekgk.WllfdDskVtevkeee 321
                                                    ++++Li+vv+H G s+ssGHY+++v++ k++ Wl+++D  V+ ++e+ 
   Q: 835  nslpelpcsdedsgnedvldmeyseaeaenlkrnaesgdvANSFRLISVVSHIGsSSSSGHYISDVYDMKKQsWLTYNDLDVSRTQEAA 923
           7777777777777777777777777788888888888888****************************88888**************** PP
   S: 322  vleetgstaYvlfYkr 337
           v++++++++Y++fY++
   Q: 924  VQRDRDRSGYIFFYMH 939
           **************98 PP

UBD/Alpha-Helix/UIM

   S: 2    EdeeLqlAlalSlqEeee 19
           E++eLq+Ala+SlqE+e 
   Q: 796  EEQELQQALAQSLQEHEA 813
           9***************95 PP

UBD/Alpha-Helix/UIM

   S: 2    EdeeLqlAlalSlqEeee 19
           +de+L+  l++S+qE++ 
   Q: 697  DDEMLAAVLEMSRQEAGL 714
           9**************976 PP

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

MSTIVPKLSS GGAVKIRLEN SDVGATRWRE GTYEILEKEN KVNLYIRFTC GRASKTFQLN 60
QNLKTVTQNL SRLHLTLKDR NVIIFDKMPP TLLQKTKEYL ERLKLGKPTA VLKSSYGSAN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGTCGTGCG CGGGTCACTG TCAACAACAT ACGTATTGGG GAGCAGGTGA ATGCCGGCAA 60
AACAAACTTT GCGCCCTCGC CGGACCCACG AAGACGTTGC CGTGATTCAA AAGTTTCAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR003903--UIM_dom
IPR032069--USP37-like_PH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50330--UIM
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH
PF16674--UCH_N
PF02809--UIM

SMART

SM00726--UIM

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001400	Ailuropoda melanoleuca	53.50	0.00e+00	894.00
IUUC-Apl-004033	Anas platyrhynchos	55.36	0.00e+00	907.00
IUUC-Aca-005370	Anolis carolinensis	53.89	0.00e+00	882.00
IUUC-Ame-011884	Astyanax mexicanus	71.93	0.00e+00	1246.00
IUUC-Bta-012725	Bos taurus	54.16	0.00e+00	877.00
IUUC-Cja-019939	Callithrix jacchus	53.35	0.00e+00	874.00
IUUC-Cfa-020835	Canis familiaris	54.25	0.00e+00	915.00
IUUC-Cpo-022067	Cavia porcellus	53.05	0.00e+00	797.00
IUUC-Cre-022867	Chlamydomonas reinhardtii	29.32	2.00e-20	94.40
IUUC-Csa-023085	Chlorocebus sabaeus	53.96	0.00e+00	900.00
IUUC-Cho-024390	Choloepus hoffmanni	49.32	1.00e-62	235.00
IUUC-Cin-025496	Ciona intestinalis	32.56	2.00e-42	167.00
IUUC-Csv-025812	Ciona savignyi	30.05	1.00e-37	151.00
IUUC-Dre-028255	Danio rerio	70.32	0.00e+00	1213.00
IUUC-Dno-028986	Dasypus novemcinctus	53.00	0.00e+00	873.00
IUUC-Dor-031062	Dipodomys ordii	42.79	2.00e-124	440.00
IUUC-Ete-032359	Echinops telfairi	53.60	1.00e-103	371.00
IUUC-Eca-033964	Equus caballus	53.75	0.00e+00	897.00
IUUC-Eeu-034492	Erinaceus europaeus	50.70	4.00e-124	439.00
IUUC-Fca-036359	Felis catus	53.75	0.00e+00	897.00
IUUC-Fal-037640	Ficedula albicollis	55.93	0.00e+00	887.00
IUUC-Gmo-039600	Gadus morhua	77.21	0.00e+00	1355.00
IUUC-Gga-040126	Gallus gallus	54.99	0.00e+00	852.00
IUUC-Ggo-045571	Gorilla gorilla	51.26	0.00e+00	776.00
IUUC-Hsa-046043	Homo sapiens	53.31	0.00e+00	885.00
IUUC-Itr-048207	Ictidomys tridecemlineatus	53.97	0.00e+00	876.00
IUUC-Lch-050357	Latimeria chalumnae	52.17	0.00e+00	750.00
IUUC-Loc-052849	Lepisosteus oculatus	69.22	0.00e+00	1156.00
IUUC-Laf-054570	Loxodonta africana	53.29	0.00e+00	853.00
IUUC-Mcc-054989	Macaca mulatta	52.58	0.00e+00	808.00
IUUC-Meu-056273	Macropus eugenii	43.69	5.00e-42	166.00
IUUC-Mga-059814	Meleagris gallopavo	53.88	0.00e+00	846.00
IUUC-Mmr-061726	Microcebus murinus	53.70	0.00e+00	892.00
IUUC-Mdo-062974	Monodelphis domestica	54.84	0.00e+00	907.00
IUUC-Mmu-064069	Mus musculus	53.85	0.00e+00	877.00
IUUC-Mpu-066008	Mustela putorius furo	53.65	0.00e+00	893.00
IUUC-Mlu-068224	Myotis lucifugus	32.51	2.00e-101	363.00
IUUC-Nle-069259	Nomascus leucogenys	53.11	0.00e+00	882.00
IUUC-Opr-070882	Ochotona princeps	69.49	1.00e-83	304.00
IUUC-Ont-072441	Oreochromis niloticus	84.47	0.00e+00	1498.00
IUUC-Oan-073151	Ornithorhynchus anatinus	59.70	5.00e-85	307.00
IUUC-Ocu-074879	Oryctolagus cuniculus	53.76	0.00e+00	882.00
IUUC-Ola-087007	Oryzias latipes	76.47	0.00e+00	1295.00
IUUC-Oga-088385	Otolemur garnettii	52.78	0.00e+00	877.00
IUUC-Oar-090305	Ovis aries	53.75	0.00e+00	894.00
IUUC-Ptr-091299	Pan troglodytes	53.31	0.00e+00	882.00
IUUC-Pan-091996	Papio anubis	54.58	0.00e+00	880.00
IUUC-Psi-093176	Pelodiscus sinensis	55.80	0.00e+00	911.00
IUUC-Pma-094331	Petromyzon marinus	44.36	3.00e-178	619.00
IUUC-Pfo-096503	Poecilia formosa	79.57	0.00e+00	1367.00
IUUC-Pab-098543	Pongo abelii	58.04	3.00e-153	536.00
IUUC-Pca-101099	Procavia capensis	53.00	0.00e+00	710.00
IUUC-Pva-103163	Pteropus vampyrus	51.64	3.00e-170	592.00
IUUC-Rno-105766	Rattus norvegicus	53.55	0.00e+00	871.00
IUUC-Sha-106610	Sarcophilus harrisii	51.80	0.00e+00	818.00
IUUC-Sar-113624	Sorex araneus	43.08	5.00e-55	209.00
IUUC-Ssc-116353	Sus scrofa	54.05	0.00e+00	870.00
IUUC-Tgu-116971	Taeniopygia guttata	56.13	0.00e+00	867.00
IUUC-Tru-117932	Takifugu rubripes	56.33	0.00e+00	627.00
IUUC-Tsy-119185	Tarsius syrichta	52.58	2.00e-174	606.00
IUUC-Tni-119842	Tetraodon nigroviridis	69.05	2.00e-131	462.00
IUUC-Tbe-127281	Tupaia belangeri	39.72	3.00e-65	243.00
IUUC-Ttr-128177	Tursiops truncatus	58.72	0.00e+00	773.00
IUUC-Vpa-130031	Vicugna pacos	53.61	0.00e+00	892.00
IUUC-Xtr-132949	Xenopus tropicalis	54.27	0.00e+00	852.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence