iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062833

UUCD1 version

UUC-MoD-01136

Ensembl Protein ID

ENSMODP00000000384.3

UniProt Accession

F6VUC6; F6VUC6_MONDO

Protein Name

Uncharacterized protein

Gene Name

USP38

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000000319.4	ENSMODT00000000391.4	ENSMODP00000000384.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.80e-82	276.0	445	952

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           tGl NlgNtCYmNSv+Q+L++ +++r+ +l+ + + +n         +l+k+lq+lf+ l +++++a++pr +++a +   + f+  +q
   Q: 445  TGLINLGNTCYMNSVIQALFMATDFRRHVLSLNLNGCN---------SLMKKLQHLFAFLAHTQREAYAPRIFFEASR--PPWFTPRSQ 522
           7******************************5555554.........7***************************998..777****** PP
   S: 90   qDaqEflaflldqleeelkk...eknkpkeeeeeedkselsde........aeekkkkknkslisdlFqgqlksqikclecdnvssree 167
           qD++E+l+flld+l+ee       ++ + +e++++++ +l++         +   +++++k+li+++F+g+l+++i cl+c+++s++ee
   Q: 523  QDCSEYLRFLLDRLHEEERTlkaLSSLKPSESMGSNEASLQEVtnkaapftEIPYTNESEKTLIEKMFGGKLQTNIHCLNCRSISQKEE 611
           *****************94455522223333333333333333677777766677888889**************************** PP
   S: 168  pfldlslpvpgkeetkke....................................................................... 185
            f+dlsl++  ++ ++++                                                                       
   Q: 612  AFTDLSLAFCPSSPMENLsfqgppcspkvqddfvvqasvvtadspeesalchpvptgfdsetvmdeaaldnlpselhctentlvsnepc 700
           **********999776669********************************************************************** PP
   S: 186  ..................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefp 256
                             s++d+L+ f ++e l+g+n+yyce+c ++q+aek++++ + Pe+Lil L Rfs++++ + r+ki ++v++p
   Q: 701  kiqinrgvsqkpggettpSVTDLLNYFLAPEILNGDNRYYCENCASLQNAEKTMQIMEEPEYLILTLLRFSYDQKCHIRRKILDNVSLP 789
           ***************************************************************************************** PP
   S: 257  leLdlspfcts.....peekqke................................kkkYeLiavvvHsG.slssGHYvayvkn...... 301
           l L+l    t+           +                                 + Y L++vvvHsG s++sGHY++y++n      
   Q: 790  LVLELPVKRTNssltsL-----SeswsvdvdftdtgenlakklkssetdeaccpkLVPYLLSSVVVHSGiSSESGHYYSYARNitgsds 873
           99999865555234440.....34566666666666666666667777778888899******************************** PP
   S: 302  ......................................ekgkWllfdDskVtevkeeevleetg....staYvlfYkrr 338
                                                  +++W+lf+Ds+Vt ++ ++v++ t+    +taYvl+Yk++
   Q: 874  sfqlchqsetlalaspqghllggeiptavieqdlenneMSKEWFLFNDSRVTFTSFQSVQKITSrfpkDTAYVLLYKKQ 952
           **************9999999999999999988866544555*******************999************986 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MDKILEGLVS STHSLTVKRV IVRKVVESAE NWVDKAQCEA MFGLTTRLIL EGQDPFQRQV 60
GHQVLEAYAR YHRSEFESFF NKSFVLGLLQ RGYRTLDRKD VAILDYIHNG LKLIMSCPSV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACAAGA TCCTGGAGGG CCTGGTGAGC TCGACACACT CGCTGACAGT CAAGAGAGTG 60
ATCGTGCGGA AAGTGGTGGA GTCGGCCGAG AACTGGGTGG ACAAGGCGCA GTGCGAGGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR033840--USP38
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

mdo:100019234

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002174	Ailuropoda melanoleuca	84.46	0.00e+00	1658.00
IUUC-Apl-003435	Anas platyrhynchos	77.80	0.00e+00	1311.00
IUUC-Aca-004556	Anolis carolinensis	72.12	0.00e+00	1327.00
IUUC-Ame-010616	Astyanax mexicanus	62.25	0.00e+00	1239.00
IUUC-Bta-013544	Bos taurus	85.93	0.00e+00	1681.00
IUUC-Cja-018745	Callithrix jacchus	83.51	0.00e+00	1670.00
IUUC-Cfa-020434	Canis familiaris	82.39	0.00e+00	1631.00
IUUC-Cpo-021666	Cavia porcellus	84.89	0.00e+00	1627.00
IUUC-Csa-023965	Chlorocebus sabaeus	86.12	0.00e+00	1772.00
IUUC-Cho-024809	Choloepus hoffmanni	78.44	0.00e+00	1191.00
IUUC-Cin-025604	Ciona intestinalis	37.83	1.00e-41	164.00
IUUC-Csv-026333	Ciona savignyi	43.68	3.00e-33	135.00
IUUC-Dre-028338	Danio rerio	62.02	0.00e+00	1227.00
IUUC-Dno-029372	Dasypus novemcinctus	87.56	0.00e+00	1735.00
IUUC-Dor-030752	Dipodomys ordii	81.24	0.00e+00	1127.00
IUUC-Dme-031871	Drosophila melanogaster	29.68	4.00e-45	176.00
IUUC-Ete-032588	Echinops telfairi	74.77	0.00e+00	1076.00
IUUC-Eca-034416	Equus caballus	86.22	0.00e+00	1758.00
IUUC-Eeu-035132	Erinaceus europaeus	67.65	0.00e+00	1295.00
IUUC-Fca-036137	Felis catus	86.22	0.00e+00	1749.00
IUUC-Fal-037297	Ficedula albicollis	77.41	0.00e+00	1491.00
IUUC-Gmo-038727	Gadus morhua	65.91	0.00e+00	1021.00
IUUC-Gga-041091	Gallus gallus	75.10	0.00e+00	1411.00
IUUC-Gac-042082	Gasterosteus aculeatus	64.53	0.00e+00	1159.00
IUUC-Ggo-045376	Gorilla gorilla	81.32	0.00e+00	1600.00
IUUC-Hsa-046444	Homo sapiens	86.03	0.00e+00	1737.00
IUUC-Itr-047976	Ictidomys tridecemlineatus	85.36	0.00e+00	1721.00
IUUC-Lch-050500	Latimeria chalumnae	72.12	0.00e+00	1442.00
IUUC-Loc-052625	Lepisosteus oculatus	65.60	0.00e+00	1309.00
IUUC-Laf-053689	Loxodonta africana	86.85	0.00e+00	1743.00
IUUC-Mcc-055286	Macaca mulatta	85.74	0.00e+00	1721.00
IUUC-Mga-059905	Meleagris gallopavo	75.90	0.00e+00	1271.00
IUUC-Mmr-061397	Microcebus murinus	86.12	0.00e+00	1714.00
IUUC-Mmu-063157	Mus musculus	83.64	0.00e+00	1666.00
IUUC-Mpu-066434	Mustela putorius furo	85.55	0.00e+00	1722.00
IUUC-Mlu-068178	Myotis lucifugus	84.38	0.00e+00	1640.00
IUUC-Nle-070153	Nomascus leucogenys	85.17	0.00e+00	1657.00
IUUC-Ont-072330	Oreochromis niloticus	63.75	0.00e+00	1257.00
IUUC-Oan-072709	Ornithorhynchus anatinus	86.57	0.00e+00	1414.00
IUUC-Ocu-074832	Oryctolagus cuniculus	86.03	0.00e+00	1709.00
IUUC-Ola-087003	Oryzias latipes	54.19	8.00e-49	186.00
IUUC-Oga-088517	Otolemur garnettii	81.71	0.00e+00	1613.00
IUUC-Oar-089472	Ovis aries	82.20	0.00e+00	1602.00
IUUC-Ptr-090996	Pan troglodytes	85.74	0.00e+00	1732.00
IUUC-Pan-091837	Papio anubis	83.84	0.00e+00	1701.00
IUUC-Psi-093236	Pelodiscus sinensis	80.37	0.00e+00	1245.00
IUUC-Pma-094349	Petromyzon marinus	52.47	0.00e+00	959.00
IUUC-Pfo-097193	Poecilia formosa	62.27	0.00e+00	1143.00
IUUC-Pab-098710	Pongo abelii	85.36	0.00e+00	1733.00
IUUC-Pca-100794	Procavia capensis	76.39	0.00e+00	1496.00
IUUC-Pva-102722	Pteropus vampyrus	84.51	0.00e+00	1700.00
IUUC-Rno-105743	Rattus norvegicus	83.35	0.00e+00	1647.00
IUUC-Sha-106563	Sarcophilus harrisii	96.77	0.00e+00	1679.00
IUUC-Sar-113533	Sorex araneus	73.01	0.00e+00	1432.00
IUUC-Ssc-116259	Sus scrofa	77.06	0.00e+00	1431.00
IUUC-Tgu-117475	Taeniopygia guttata	77.26	0.00e+00	1367.00
IUUC-Tru-118623	Takifugu rubripes	63.36	0.00e+00	1151.00
IUUC-Tsy-119250	Tarsius syrichta	83.97	0.00e+00	1351.00
IUUC-Tni-120441	Tetraodon nigroviridis	59.60	0.00e+00	1064.00
IUUC-Tbe-127936	Tupaia belangeri	74.26	0.00e+00	1389.00
IUUC-Ttr-128483	Tursiops truncatus	73.11	0.00e+00	1275.00
IUUC-Vpa-130303	Vicugna pacos	93.63	0.00e+00	1035.00
IUUC-Xtr-132773	Xenopus tropicalis	72.49	0.00e+00	1413.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence