iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066434

Ensembl Protein ID

ENSMPUP00000000823.1

UniProt Accession

M3XP23; M3XP23_MUSPF

Genbank Protein ID

ENSMPUP00000000823

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01085647

Gene Name

USP38

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000000827.1	ENSMPUT00000000839.1	ENSMPUP00000000823.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.20e-82	277.9	445	949

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           tGl NlgNtCYmNSv+Q+L++ +++r+++l+ + + +n         +l+k+lq+lf+ l +++++a++pr +++a +   + f++ +q
   Q: 445  TGLINLGNTCYMNSVIQALFMATDFRRQVLSLNLNGCN---------SLMKKLQHLFAFLAHTQREAYAPRVFFEASR--PPWFTSRSQ 522
           7******************************5555554.........7***************************998..777****** PP
   S: 90   qDaqEflaflldqleeelkk...eknkpkeeeeeedkselsde........aeekkkkknkslisdlFqgqlksqikclecdnvssree 167
           qD++E+l+flld+l+ee k    +++++ +e+ + ++++l++         ++  +   +k+li+++F+g+l+++i cl+c+++s++ e
   Q: 523  QDCSEYLRFLLDRLHEEEKIlkvQSSHKPSESLGCNETSLQEVaskaavlaESPCTSDGEKTLIEKMFGGKLRTHICCLNCRSTSQKVE 611
           *****************95577788888888888888888888888888877777777888**************************** PP
   S: 168  pfldlslpvpgkeetkke....................................................................... 185
            f+dlsl++  +++ +++                                                                       
   Q: 612  AFTDLSLAFCPSSSVENLsfqdpassastqdgglmqasvpgpseepgvynpataafvcdsamnermlgspsdefcctentcvpsessti 700
           *********9999766669********************************************************************** PP
   S: 186  ................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple 258
                           s++d+L+ f ++e l+g+n+yyce+c ++q+aek++++++ Pe+Lil L Rfs++++ ++r+ki ++v++pl 
   Q: 701  lvnkdvpqkpgggstpSVTDLLNYFLAPEILTGDNQYYCENCASLQNAEKTMQITEEPEYLILTLLRFSYDQKYHVRRKILDNVSLPLV 789
           ***************************************************************************************** PP
   S: 259  Ldlspfcts...............................peekqke.....kkkYeLiavvvHsG.slssGHYvayvkn......... 301
           L+l    t+                               +     e      + Y L++vvvHsG s++sGHY++y++n         
   Q: 790  LELPVKRTTsfsslseswsidvdftdvsenlakklkpsgtE-----EtccsrLVPYLLSSVVVHSGiSSESGHYYSYARNitgtessyq 873
           99996555535556666666666666655555555544443.....0555559************************************ PP
   S: 302  ...................................ekgkWllfdDskVtevkeeevleetg....staYvlfYkrr 338
                                               +++W+lf+Ds+Vt ++ ++v++ t+    +taYvl+Yk++
   Q: 874  mchqsetlalassqshflernspsavieqdlenkeMSKEWFLFNDSRVTFTSFQSVQKITSrfpkDTAYVLLYKKQ 949
           ***********9999999999999999988865544555*******************999************986 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MDKILEGLVS SSHPLPLKRV IVRKVVESAE HWLDEAQCEA MFDLTTRLIL EGQDPFQRQV 60
GHQVLEAYAR YHRPEFESFF NKTFVLGLLQ QGYHSLDRKD VAILDYIHNG LKLIMSCPSV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACAAGA TCCTGGAGGG CCTGGTGAGT TCTTCGCACC CACTGCCCCT AAAGCGGGTG 60
ATTGTGCGGA AGGTGGTGGA ATCGGCGGAG CATTGGCTGG ACGAGGCGCA GTGTGAAGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR033840--USP38
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002174	Ailuropoda melanoleuca	96.75	0.00e+00	1928.00
IUUC-Apl-003435	Anas platyrhynchos	76.76	0.00e+00	1270.00
IUUC-Aca-004556	Anolis carolinensis	71.13	0.00e+00	1308.00
IUUC-Ame-010616	Astyanax mexicanus	62.55	0.00e+00	1238.00
IUUC-Bta-013544	Bos taurus	93.67	0.00e+00	1850.00
IUUC-Cja-018745	Callithrix jacchus	91.78	0.00e+00	1871.00
IUUC-Cfa-020434	Canis familiaris	92.23	0.00e+00	1842.00
IUUC-Cpo-021666	Cavia porcellus	91.94	0.00e+00	1793.00
IUUC-Csa-023965	Chlorocebus sabaeus	94.15	0.00e+00	1958.00
IUUC-Cho-024809	Choloepus hoffmanni	84.47	0.00e+00	1280.00
IUUC-Cin-025604	Ciona intestinalis	37.83	2.00e-41	162.00
IUUC-Csv-026333	Ciona savignyi	45.14	5.00e-32	130.00
IUUC-Dre-028338	Danio rerio	62.85	0.00e+00	1249.00
IUUC-Dno-029372	Dasypus novemcinctus	92.51	0.00e+00	1862.00
IUUC-Dor-030752	Dipodomys ordii	89.86	0.00e+00	1252.00
IUUC-Ete-032588	Echinops telfairi	80.65	0.00e+00	1149.00
IUUC-Eca-034416	Equus caballus	95.87	0.00e+00	1980.00
IUUC-Eeu-035132	Erinaceus europaeus	74.93	0.00e+00	1415.00
IUUC-Fca-036137	Felis catus	96.07	0.00e+00	1949.00
IUUC-Fal-037297	Ficedula albicollis	75.98	0.00e+00	1456.00
IUUC-Gmo-038727	Gadus morhua	65.91	0.00e+00	1018.00
IUUC-Gga-041091	Gallus gallus	74.50	0.00e+00	1408.00
IUUC-Gac-042082	Gasterosteus aculeatus	63.57	0.00e+00	1139.00
IUUC-Ggo-045376	Gorilla gorilla	89.20	0.00e+00	1776.00
IUUC-Hsa-046444	Homo sapiens	94.15	0.00e+00	1920.00
IUUC-Itr-047976	Ictidomys tridecemlineatus	93.67	0.00e+00	1917.00
IUUC-Lch-050500	Latimeria chalumnae	72.78	0.00e+00	1439.00
IUUC-Loc-052625	Lepisosteus oculatus	64.81	0.00e+00	1303.00
IUUC-Laf-053689	Loxodonta africana	93.46	0.00e+00	1887.00
IUUC-Mcc-055286	Macaca mulatta	94.24	0.00e+00	1921.00
IUUC-Mga-059905	Meleagris gallopavo	75.00	0.00e+00	1244.00
IUUC-Mmr-061397	Microcebus murinus	94.34	0.00e+00	1906.00
IUUC-Mdo-062833	Monodelphis domestica	86.12	0.00e+00	1791.00
IUUC-Mmu-063157	Mus musculus	90.31	0.00e+00	1815.00
IUUC-Mlu-068178	Myotis lucifugus	93.51	0.00e+00	1848.00
IUUC-Nle-070153	Nomascus leucogenys	93.47	0.00e+00	1851.00
IUUC-Ont-072330	Oreochromis niloticus	63.64	0.00e+00	1252.00
IUUC-Oan-072709	Ornithorhynchus anatinus	81.52	0.00e+00	1300.00
IUUC-Ocu-074832	Oryctolagus cuniculus	93.86	0.00e+00	1886.00
IUUC-Ola-087003	Oryzias latipes	56.67	3.00e-50	191.00
IUUC-Oga-088517	Otolemur garnettii	89.11	0.00e+00	1797.00
IUUC-Oar-089472	Ovis aries	90.02	0.00e+00	1779.00
IUUC-Ptr-090996	Pan troglodytes	93.76	0.00e+00	1913.00
IUUC-Pan-091837	Papio anubis	92.37	0.00e+00	1908.00
IUUC-Psi-093236	Pelodiscus sinensis	76.35	0.00e+00	1179.00
IUUC-Pma-094349	Petromyzon marinus	53.15	0.00e+00	990.00
IUUC-Pfo-097193	Poecilia formosa	62.79	0.00e+00	1168.00
IUUC-Pab-098710	Pongo abelii	93.95	0.00e+00	1938.00
IUUC-Pca-100794	Procavia capensis	82.74	0.00e+00	1650.00
IUUC-Pva-102722	Pteropus vampyrus	94.06	0.00e+00	1912.00
IUUC-Rno-105743	Rattus norvegicus	89.06	0.00e+00	1782.00
IUUC-Sha-106563	Sarcophilus harrisii	84.79	0.00e+00	1446.00
IUUC-Sar-113533	Sorex araneus	78.69	0.00e+00	1576.00
IUUC-Ssc-116259	Sus scrofa	84.21	0.00e+00	1596.00
IUUC-Tgu-117475	Taeniopygia guttata	75.68	0.00e+00	1322.00
IUUC-Tru-118623	Takifugu rubripes	63.19	0.00e+00	1160.00
IUUC-Tsy-119250	Tarsius syrichta	92.74	0.00e+00	1489.00
IUUC-Tni-120441	Tetraodon nigroviridis	59.49	0.00e+00	1073.00
IUUC-Tbe-127936	Tupaia belangeri	80.81	0.00e+00	1553.00
IUUC-Ttr-128483	Tursiops truncatus	81.45	0.00e+00	1435.00
IUUC-Vpa-130303	Vicugna pacos	97.94	0.00e+00	1077.00
IUUC-Xtr-132773	Xenopus tropicalis	72.81	0.00e+00	1412.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence