iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tru-118262

Ensembl Protein ID

ENSTRUP00000025019.1

UniProt Accession

H2TK15; H2TK15_TAKRU

Protein Name

Inhibitor of growth protein

Gene Name

ing1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000009949.1	ENSTRUT00000025121.1	ENSTRUP00000025018.1
ENSTRUG00000009949.1	ENSTRUT00000025122.1	ENSTRUP00000025019.1
ENSTRUG00000009949.1	ENSTRUT00000025123.1	ENSTRUP00000025020.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	4.60e-08	34.4	240	287

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C++ + +e  ++ C++  C+ ewfH+ C++l     +p+ + w+CpkCr 
   Q: 240  TYC-LCEQVSYGE--MIGCDNdeCSiEWFHFSCVGLH---HKPKGK-WYCPKCRG 287
           69*.*******99..*****99*999***********...999997.******85 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MLNPSNGDPN QVVVNYVEEY LELVESLPCD LQRSVSLMKE IDAKYQDVLK ELDDAYERYR 60
RESDSLQRRK LQMSIQRALI RSQELGDEKI QIAGQMVELV ENRTRQIDWH SQLLLSSQEV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACGTTGTATG CAGAATCATC TTATATTTAA GTAAATGTTT ACATCATAAT TGAATGAACT 60
CGCCATTTGA CTGTCTAGTC AGCGCTGGGG GTTCGTGTTT TTGTCGCAGC GGAATATAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028643--ING1
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0008285--P:negative regulation of cell proliferation
GO:0010941--P:regulation of cell death

KEGG

tru:101077238

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003910	Anas platyrhynchos	57.00	1.00e-82	299.00
IUUC-Ame-011262	Astyanax mexicanus	59.87	2.00e-85	308.00
IUUC-Dno-029834	Dasypus novemcinctus	56.96	5.00e-85	307.00
IUUC-Dor-030315	Dipodomys ordii	56.70	2.00e-69	256.00
IUUC-Dse-031323	Dothistroma septosporum	51.35	4.00e-18	86.70
IUUC-Fal-036838	Ficedula albicollis	57.47	1.00e-83	302.00
IUUC-Gmo-038557	Gadus morhua	81.82	8.00e-53	200.00
IUUC-Gga-040619	Gallus gallus	57.14	8.00e-83	300.00
IUUC-Gac-041996	Gasterosteus aculeatus	80.46	5.00e-126	443.00
IUUC-Lch-050397	Latimeria chalumnae	57.61	3.00e-84	304.00
IUUC-Loc-052038	Lepisosteus oculatus	59.51	5.00e-80	290.00
IUUC-Laf-054126	Loxodonta africana	57.47	8.00e-85	306.00
IUUC-Meu-056248	Macropus eugenii	54.51	1.00e-65	243.00
IUUC-Mga-059217	Meleagris gallopavo	55.34	2.00e-64	238.00
IUUC-Mdo-062452	Monodelphis domestica	57.28	2.00e-84	305.00
IUUC-Mlu-067586	Myotis lucifugus	52.40	2.00e-76	278.00
IUUC-Ont-071606	Oreochromis niloticus	87.99	6.00e-126	443.00
IUUC-Ola-086891	Oryzias latipes	78.57	3.00e-119	421.00
IUUC-Pma-094265	Petromyzon marinus	74.39	9.00e-35	139.00
IUUC-Pfo-097531	Poecilia formosa	84.24	4.00e-133	467.00
IUUC-Sha-107270	Sarcophilus harrisii	57.93	2.00e-85	308.00
IUUC-Tgu-116822	Taeniopygia guttata	57.47	9.00e-84	303.00
IUUC-Tni-119980	Tetraodon nigroviridis	90.26	2.00e-130	458.00
IUUC-Tre-121950	Trichoderma reesei	64.29	2.00e-19	91.70

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence