iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000014093.2	ENSCJAT00000027456.2	ENSCJAP00000025981.2
ENSCJAG00000014093.2	ENSCJAT00000027415.1	ENSCJAP00000025942.1
ENSCJAG00000014093.2	ENSCJAT00000027448.2	ENSCJAP00000025973.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	6.80e-15	55.7	115	169

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +v++ ++++ +n+deL++ kGdv++v     +++gW++g  +l+g+ G fP+n+v++++
   Q: 115  VVRAKFNFQQNNEDELSFSKGDVIHVT--RVEEGGWWEG--TLNGRTGWFPSNYVREVK 169
           78999*********************7..999*******..8**************996 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

LWIALLFPRK LTGQHLHPTK TLLILLFNFS FQTFDANDLY QGQNFNKVLS SLVTLNKVTA 60
DIGLGSDSVC ARPSSHRIKS FDSLGSQSLH TRTSKLFQGQ YRSLDMTDNS NNQLVVRAKF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGTGGATTG CTCTCCTGTT TCCTAGAAAG CTTACAGGGC AGCAGGAAGA AACGGGTTAG 60
CTATGTCTTT ACTGGTAGAG CTGAGCTTCG GGTGCCATCT CTGCCATGTG TTCGGCATCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-1185--Reference proteome

Interpro

IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF00169--PH
PF00621--RhoGEF
PF07653--SH3_2

PRINTS

PR00452--SH3DOMAIN

SMART

SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0005925--C:focal adhesion
GO:0030027--C:lamellipodium
GO:0043005--C:neuron projection
GO:0043025--C:neuronal cell body
GO:0005886--C:plasma membrane
GO:0043234--C:protein complex
GO:0000322--C:storage vacuole
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0048041--P:focal adhesion assembly
GO:0007030--P:Golgi organization
GO:0002244--P:hematopoietic progenitor cell differentiation
GO:0035556--P:intracellular signal transduction
GO:0030032--P:lamellipodium assembly
GO:0043065--P:positive regulation of apoptotic process
GO:0010763--P:positive regulation of fibroblast migration
GO:0060124--P:positive regulation of growth hormone secretion
GO:2000394--P:positive regulation of lamellipodium morphogenesis
GO:0032092--P:positive regulation of protein binding
GO:1900026--P:positive regulation of substrate adhesion-dependent cell spreading
GO:1904424--P:regulation of GTP binding
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001259	Ailuropoda melanoleuca	94.89	0.00e+00	1216.00
IUUC-Aca-004591	Anolis carolinensis	91.44	0.00e+00	1098.00
IUUC-Ago-008003	Ashbya gossypii	25.00	8.00e-15	75.90
IUUC-Ame-010759	Astyanax mexicanus	76.22	0.00e+00	1013.00
IUUC-Bta-013328	Bos taurus	94.19	0.00e+00	1199.00
IUUC-Bci-013864	Botrytis cinerea	41.54	5.00e-12	67.00
IUUC-Cfa-020756	Canis familiaris	94.30	0.00e+00	1140.00
IUUC-Cpo-021284	Cavia porcellus	92.15	0.00e+00	1140.00
IUUC-Csa-023162	Chlorocebus sabaeus	98.70	0.00e+00	1248.00
IUUC-Cho-024736	Choloepus hoffmanni	73.14	9.00e-172	597.00
IUUC-Cin-025535	Ciona intestinalis	39.92	5.00e-94	338.00
IUUC-Cgl-026676	Colletotrichum gloeosporioides	41.43	1.00e-11	66.20
IUUC-Cne-026866	Cryptococcus neoformans	49.21	7.00e-13	70.10
IUUC-Dre-028646	Danio rerio	76.37	0.00e+00	1010.00
IUUC-Dno-029461	Dasypus novemcinctus	94.80	0.00e+00	1192.00
IUUC-Dor-030623	Dipodomys ordii	84.38	0.00e+00	1031.00
IUUC-Dme-032219	Drosophila melanogaster	45.99	4.00e-102	366.00
IUUC-Ete-032236	Echinops telfairi	80.24	0.00e+00	803.00
IUUC-Eca-034137	Equus caballus	96.08	0.00e+00	1190.00
IUUC-Fca-035742	Felis catus	95.23	0.00e+00	1116.00
IUUC-Fal-037205	Ficedula albicollis	93.81	0.00e+00	1024.00
IUUC-Fox-037757	Fusarium oxysporum	38.89	1.00e-11	66.20
IUUC-Fso-038433	Fusarium solani	38.89	9.00e-12	66.20
IUUC-Gmo-039475	Gadus morhua	75.83	0.00e+00	871.00
IUUC-Gga-040539	Gallus gallus	93.15	0.00e+00	972.00
IUUC-Gac-042615	Gasterosteus aculeatus	71.63	0.00e+00	818.00
IUUC-Ggo-044470	Gorilla gorilla	98.15	0.00e+00	1256.00
IUUC-Hsa-046398	Homo sapiens	96.71	0.00e+00	1271.00
IUUC-Loc-052146	Lepisosteus oculatus	85.43	0.00e+00	1091.00
IUUC-Laf-053891	Loxodonta africana	92.49	0.00e+00	1224.00
IUUC-Mcc-055483	Macaca mulatta	96.44	0.00e+00	1271.00
IUUC-Mla-059044	Melampsora laricipopulina	26.16	3.00e-18	87.80
IUUC-Mga-059410	Meleagris gallopavo	93.34	0.00e+00	1165.00
IUUC-Mmr-060758	Microcebus murinus	96.29	0.00e+00	1179.00
IUUC-Mdo-061900	Monodelphis domestica	92.42	0.00e+00	1119.00
IUUC-Mmu-063849	Mus musculus	93.17	0.00e+00	1155.00
IUUC-Mpu-065876	Mustela putorius furo	93.96	0.00e+00	1125.00
IUUC-Mlu-067970	Myotis lucifugus	95.49	0.00e+00	1185.00
IUUC-Nle-069685	Nomascus leucogenys	95.50	0.00e+00	1066.00
IUUC-Opr-071132	Ochotona princeps	64.33	0.00e+00	728.00
IUUC-Ont-071815	Oreochromis niloticus	75.60	0.00e+00	1003.00
IUUC-Oan-073057	Ornithorhynchus anatinus	92.35	0.00e+00	1033.00
IUUC-Ola-086663	Oryzias latipes	74.37	0.00e+00	931.00
IUUC-Oga-088103	Otolemur garnettii	95.09	0.00e+00	1150.00
IUUC-Ptr-091162	Pan troglodytes	98.73	0.00e+00	1278.00
IUUC-Pan-092093	Papio anubis	86.16	0.00e+00	1090.00
IUUC-Pma-094261	Petromyzon marinus	66.88	2.00e-126	444.00
IUUC-Pfo-096736	Poecilia formosa	70.83	0.00e+00	900.00
IUUC-Pab-097641	Pongo abelii	98.42	0.00e+00	1184.00
IUUC-Pva-102819	Pteropus vampyrus	91.71	0.00e+00	1141.00
IUUC-Pgr-103400	Puccinia graminis	26.58	2.00e-19	92.00
IUUC-Pte-104123	Pyrenophora teres	42.86	1.00e-10	62.40
IUUC-Pyt-104567	Pyrenophora triticirepentis	42.86	1.00e-10	62.40
IUUC-Rno-106099	Rattus norvegicus	92.92	0.00e+00	1127.00
IUUC-Sha-106845	Sarcophilus harrisii	92.41	0.00e+00	1118.00
IUUC-Ssl-108538	Sclerotinia sclerotiorum	42.37	4.00e-11	64.30
IUUC-Sly-111123	Solanum lycopersicum	46.15	7.00e-10	57.80
IUUC-Stu-112434	Solanum tuberosum	46.15	8.00e-10	57.80
IUUC-Ssc-116036	Sus scrofa	93.99	0.00e+00	1119.00
IUUC-Tgu-117498	Taeniopygia guttata	93.21	0.00e+00	1165.00
IUUC-Tru-118278	Takifugu rubripes	73.66	0.00e+00	942.00
IUUC-Tsy-118990	Tarsius syrichta	94.70	0.00e+00	970.00
IUUC-Tni-120852	Tetraodon nigroviridis	73.73	0.00e+00	893.00
IUUC-Ttr-128922	Tursiops truncatus	90.83	0.00e+00	1113.00
IUUC-Xtr-132012	Xenopus tropicalis	84.68	0.00e+00	957.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence