iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-073073

UUCD1 version

UUC-OrA-00051

Ensembl Protein ID

ENSOANP00000001433.1

UniProt Accession

F6QG34; F6QG34_ORNAN

Protein Name

Uncharacterized protein

Gene Name

KLHL20

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000000918.2	ENSOANT00000001433.1	ENSOANP00000001432.1
ENSOANG00000000918.2	ENSOANT00000001434.1	ENSOANP00000001433.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	3.90e-22	78.6	68	135
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.50e-11	43.3	167	198

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           +Dv+lvvg +++ ah+++L+a+S++F+a+f++el es+ + +v+i+d++  +++ l++F Yt++++ +e
   Q: 68   CDVVLVVGAKKIYAHRVILSACSPYFRAMFTGELAESR-QTEVVIRDIDERAMELLIDFAYTSQITVEE 135
           9*************************************.*************************98765 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           ++Nclgi++fAd+++c++L   a++f++++F+
   Q: 167  PSNCLGIRAFADTHSCRELLRIADKFTQHNFQ 198
           89*****************************6 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

CRKKPRSRCT GTRPGETGMD VTSRCTLGDP NKLPEGVPQP ARMPYVSDKH PRQTLEVINL 60
LRKHRELCDV VLVVGAKKIY AHRVILSACS PYFRAMFTGE LAESRQTEVV IRDIDERAME 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGAGGAC AACCTTTTCA AGGCCACCAG CCAGGCAAGT GTTTAGAAGA GGGAAGCTGC 60
AGTTATTAAG AGCAGAGGCC AATGGTAATG CCATGCGAGG CTGGAAATTT AAAGAGTGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR011043--Gal_Oxase/kelch_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0016605--C:PML body
GO:0005802--C:trans-Golgi network
GO:0019964--F:interferon-gamma binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0006895--P:Golgi to endosome transport
GO:0043066--P:negative regulation of apoptotic process
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:1990390--P:protein K33-linked ubiquitination
GO:0035455--P:response to interferon-alpha

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001974	Ailuropoda melanoleuca	99.17	0.00e+00	1243.00
IUUC-Apl-003481	Anas platyrhynchos	99.34	0.00e+00	1250.00
IUUC-Aca-004877	Anolis carolinensis	98.84	0.00e+00	1244.00
IUUC-Aly-005957	Arabidopsis lyrata	36.30	3.00e-40	159.00
IUUC-Ath-007066	Arabidopsis thaliana	35.93	1.00e-39	157.00
IUUC-Aor-010180	Aspergillus oryzae	24.65	7.00e-10	57.40
IUUC-Ate-010500	Aspergillus terreus	27.95	1.00e-18	87.40
IUUC-Ame-011440	Astyanax mexicanus	99.15	0.00e+00	1222.00
IUUC-Bta-012603	Bos taurus	99.01	0.00e+00	1246.00
IUUC-Bra-016881	Brassica rapa	27.27	3.00e-17	83.20
IUUC-Cel-018464	Caenorhabditis elegans	59.51	0.00e+00	716.00
IUUC-Cja-019119	Callithrix jacchus	99.01	0.00e+00	1246.00
IUUC-Cfa-020169	Canis familiaris	99.01	0.00e+00	1246.00
IUUC-Cpo-021519	Cavia porcellus	99.01	0.00e+00	1245.00
IUUC-Csa-024173	Chlorocebus sabaeus	99.01	0.00e+00	1246.00
IUUC-Cho-024820	Choloepus hoffmanni	95.29	0.00e+00	784.00
IUUC-Cin-025270	Ciona intestinalis	75.68	0.00e+00	891.00
IUUC-Csv-026308	Ciona savignyi	75.77	0.00e+00	899.00
IUUC-Dre-027423	Danio rerio	98.98	0.00e+00	1222.00
IUUC-Dno-029350	Dasypus novemcinctus	98.84	0.00e+00	1244.00
IUUC-Dor-031011	Dipodomys ordii	98.21	1.00e-163	569.00
IUUC-Dme-032170	Drosophila melanogaster	80.77	0.00e+00	958.00
IUUC-Ete-033187	Echinops telfairi	98.36	0.00e+00	869.00
IUUC-Eca-033751	Equus caballus	99.01	0.00e+00	1245.00
IUUC-Eeu-034901	Erinaceus europaeus	98.68	0.00e+00	1243.00
IUUC-Fca-035752	Felis catus	98.17	0.00e+00	1112.00
IUUC-Fal-037630	Ficedula albicollis	99.17	0.00e+00	1244.00
IUUC-Gmo-039481	Gadus morhua	97.36	0.00e+00	1231.00
IUUC-Gga-040971	Gallus gallus	99.34	0.00e+00	1250.00
IUUC-Gac-042602	Gasterosteus aculeatus	97.69	0.00e+00	1233.00
IUUC-Ggo-044588	Gorilla gorilla	99.01	0.00e+00	1245.00
IUUC-Hsa-046641	Homo sapiens	99.01	0.00e+00	1246.00
IUUC-Itr-048394	Ictidomys tridecemlineatus	99.34	0.00e+00	1242.00
IUUC-Lch-049968	Latimeria chalumnae	99.17	0.00e+00	1246.00
IUUC-Loc-052720	Lepisosteus oculatus	98.02	0.00e+00	1238.00
IUUC-Lma-053201	Leptosphaeria maculans	27.21	2.00e-09	56.20
IUUC-Laf-054156	Loxodonta africana	99.01	0.00e+00	1244.00
IUUC-Mcc-054629	Macaca mulatta	99.01	0.00e+00	1246.00
IUUC-Meu-056605	Macropus eugenii	99.36	0.00e+00	645.00
IUUC-Mga-060014	Meleagris gallopavo	98.68	0.00e+00	1231.00
IUUC-Mmr-060814	Microcebus murinus	98.68	0.00e+00	1244.00
IUUC-Mdo-062242	Monodelphis domestica	99.34	0.00e+00	1249.00
IUUC-Mmu-064309	Mus musculus	99.34	0.00e+00	1242.00
IUUC-Mpu-066587	Mustela putorius furo	99.01	0.00e+00	1246.00
IUUC-Mlu-066958	Myotis lucifugus	96.83	0.00e+00	1199.00
IUUC-Nle-069059	Nomascus leucogenys	97.52	0.00e+00	1222.00
IUUC-Ont-072129	Oreochromis niloticus	97.69	0.00e+00	1234.00
IUUC-Ocu-073909	Oryctolagus cuniculus	98.02	0.00e+00	1232.00
IUUC-Ola-086392	Oryzias latipes	97.04	0.00e+00	1225.00
IUUC-Olu-087696	Ostreococcus lucimarinus	36.44	4.00e-32	130.00
IUUC-Oga-088693	Otolemur garnettii	99.00	0.00e+00	1242.00
IUUC-Oar-089905	Ovis aries	98.84	0.00e+00	1244.00
IUUC-Ptr-091059	Pan troglodytes	99.01	0.00e+00	1246.00
IUUC-Pan-091833	Papio anubis	94.62	0.00e+00	788.00
IUUC-Psi-093499	Pelodiscus sinensis	99.34	0.00e+00	1242.00
IUUC-Pma-094404	Petromyzon marinus	80.17	0.00e+00	943.00
IUUC-Ppa-095249	Physcomitrella patens	31.13	7.00e-15	74.30
IUUC-Pfo-096891	Poecilia formosa	97.36	0.00e+00	1233.00
IUUC-Pab-097715	Pongo abelii	94.55	0.00e+00	1177.00
IUUC-Pva-102944	Pteropus vampyrus	82.84	0.00e+00	1013.00
IUUC-Rno-104878	Rattus norvegicus	99.01	0.00e+00	1246.00
IUUC-Sha-107444	Sarcophilus harrisii	99.34	0.00e+00	1250.00
IUUC-Ssc-115565	Sus scrofa	99.34	0.00e+00	1243.00
IUUC-Tgu-116902	Taeniopygia guttata	99.17	0.00e+00	1248.00
IUUC-Tru-118692	Takifugu rubripes	97.52	0.00e+00	1234.00
IUUC-Tsy-119031	Tarsius syrichta	91.42	0.00e+00	1127.00
IUUC-Tni-120531	Tetraodon nigroviridis	51.34	7.00e-154	536.00
IUUC-Tca-121074	Theobroma cacao	30.12	1.00e-35	144.00
IUUC-Tbe-127517	Tupaia belangeri	93.34	0.00e+00	1152.00
IUUC-Ttr-128366	Tursiops truncatus	99.01	0.00e+00	1246.00
IUUC-Vpa-130465	Vicugna pacos	98.68	0.00e+00	1242.00
IUUC-Vvi-131673	Vitis vinifera	34.33	1.00e-42	167.00
IUUC-Xtr-132243	Xenopus tropicalis	98.69	0.00e+00	1243.00
IUUC-Xma-133192	Xiphophorus maculatus	97.19	0.00e+00	1231.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence