iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gac-041342

UUCD1 version

UUC-GaA-00395

Ensembl Protein ID

ENSGACP00000010945.1

UniProt Accession

G3P022; G3P022_GASAC

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000008263.1	ENSGACT00000010958.1	ENSGACP00000010935.1
ENSGACG00000008263.1	ENSGACT00000010968.1	ENSGACP00000010945.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	2.20e-68	231.5	705	1024

Active Site

Position(s)	Description	Evidence
991	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 5    lkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlp 91
           +k++l v f+++  l +   +r+f+  ++++l  p+  + +y+e+++  ++p + +     e+  +F ++G+l+g+al++++++ +p
   Q: 705  FKRELLVLFADDRKLMN-VNKRDFFLHVFEDLTAPESDMIMYNESNTLAWFPPKPKV----EEKTYF-LFGVLCGLALYNHNIIHMP 785
           56677777777776666.6789*****************************999997....456666.66***************** PP
   S: 92   lsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvv 178
           ++ +++k+ll++k sl+d++e++p +++s   ++++  +++e+++l +++          +++eL p      Vt +Nk+e+v++ +
   Q: 786  FPLVLFKKLLKVKPSLDDMKEFEPVMAESWRCMLDYTPDEVEAMELPFAMP------WGGEDVELDPTEPGKLVTGTNKREFVDACI 866
           ************************************877777765555554......4666777*********************** PP
   S: 179  eyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafL 265
           +y ++++++  +eaf++Gf +v+++++++ F++eel+ ++ G+e++d+e lk++t y+g+y++ +p+i +Fwev+e++++ee+k+fL
   Q: 867  NYAFNKSVEGVFEAFKKGFFKVCDIDVVEFFQPEELQSVTVGQENYDWEVLKQNTVYEGEYHDLHPTIVTFWEVFEDLTAEEKKKFL 953
           *************************************************************************************** PP
   S: 266  qFvTgssrlPlgGfaelkprlfvirkdasddrlPssnTCfnyLkLPeYssk...eilkekLlyAieetkgFe 334
            FvTg++r+P+ G++++k r+ v+++ +s+ +lP+s TC  +L LP Y+ +    ++k +Ll Ai++++gF 
   Q: 954  LFVTGCDRVPFLGMESIKMRVAVLPN-SSEIHLPESLTCHCLLLLPMYQRYpveRTMKTRLLRAINHNRGFW 1024
           ******************88777777.999****************9887533389**************95 PP

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

LLCWGDSASG QFGPRDALSP ASWTVPGVIT QICCGDQCTL FLTGNGGVLS CGHNSRGQLG 60
RKTANKKVKN IKTIETSCVY DVSACGQDHC LAVCASGQVF SWGAGDGGKR GVSPNLLCNK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGACATGTCG CGGCTGCTCT GCTGGGGAGA CAGCGCCAGC GGACAGTTCG GTCCCCGGGA 60
CGCCCTGAGT CCGGCTTCGT GGACGGTGCC CGGGGTCATT ACCCAGATCT GCTGCGGGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR009091--RCC1/BLIP-II
IPR000408--Reg_chr_condens

PROSITE

PS50237--HECT
PS00626--RCC1_2
PS50012--RCC1_3

Pfam

PF00632--HECT
PF00415--RCC1

PRINTS

PR00633--RCCNDNSATION

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ame-011023	Astyanax mexicanus	44.61	0.00e+00	850.00
IUUC-Gmo-038792	Gadus morhua	53.69	0.00e+00	969.00
IUUC-Loc-052736	Lepisosteus oculatus	46.56	0.00e+00	864.00
IUUC-Ont-071328	Oreochromis niloticus	69.28	0.00e+00	1440.00
IUUC-Pfo-096202	Poecilia formosa	67.64	0.00e+00	1330.00
IUUC-Tru-117816	Takifugu rubripes	57.64	0.00e+00	1139.00
IUUC-Tni-120770	Tetraodon nigroviridis	52.15	0.00e+00	937.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence