iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-004112

Ensembl Protein ID

ENSAPLP00000005640.1

UniProt Accession

R0LT51; R0LT51_ANAPL

Genbank Protein ID

EOB04925.1

Protein Name

E3 ubiquitin-protein ligase RNF144B

Genbank Nucleotide ID

ADON01038815

Gene Name

RNF144B; Anapl_13868

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000006037.1	ENSAPLT00000006271.1	ENSAPLP00000005640.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RBR	2.20e-50	171.9	30	222

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RBR

   S: 1    CkvCllelsveeltvlleCehtfCkeClkqylelkikegqvteiscpaaecpek..leeseikellveeelykryekllleevveadaal 88
           Ck+Cl+e+s +++t+l+eC+++fC++Clkqy++l+i+eg+ + i+cp++ c ++  l+e+ei++ lv  ++++ y++l++e++v+ d+++
   Q: 30   CKLCLCEYSLDKMTTLQECSCIFCTSCLKQYMQLAIQEGCGSPITCPDMVCLNHgtLQEAEIAC-LVPVDQFQLYKRLKFEREVHLDPER 118
           ***************************************************9988899******.6999********************* PP
   S: 89   kwcpapdCslvvllekea..eklevecekcgkefCveCkeewHeglsCkelkeklakteeekeeaeskelleanskkCpkCkvyiekneg 176
           +wcpa+dC++v+ + +++    + vec++c+  fC++Cke+wH+++ C e + +l  te   + +   + +ea +k+Cp C++yie+neg
   Q: 119  TWCPAADCQTVCYIGPSEpgVPVPVECPACHLMFCSSCKETWHPQRLCPENQTTLVPTE---QGSLIGTETEAPIKQCPVCRIYIERNEG 205
           *************9998844566677************************999999999...88999999******************** PP
   S: 177  CnhmtCakCkaefCwlC 193
           C++m+C++Ck++fCw+C
   Q: 206  CAQMMCKNCKHTFCWYC 222
           ***************** PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

MGSAGKACPL TMTADKSGAG DLALEPLLTC KLCLCEYSLD KMTTLQECSC IFCTSCLKQY 60
MQLAIQEGCG SPITCPDMVC LNHGTLQEAE IACLVPVDQF QLYKRLKFER EVHLDPERTW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGCTCTG CTGGGAAGGC TTGCCCCCTC ACCATGACAG CTGACAAGTC AGGAGCTGGA 60
GACTTGGCTC TGGAGCCGCT GCTCACTTGC AAGCTATGTC TCTGTGAATA TTCCCTGGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF01485--IBR

SMART

SM00647--IBR
SM00184--RING

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0031966--C:mitochondrial membrane
GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

apla:101793521

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001257	Ailuropoda melanoleuca	81.49	5.00e-137	479.00
IUUC-Aca-004533	Anolis carolinensis	80.07	3.00e-133	467.00
IUUC-Bta-012641	Bos taurus	82.27	2.00e-136	477.00
IUUC-Cja-019626	Callithrix jacchus	72.34	1.00e-114	405.00
IUUC-Cfa-020702	Canis familiaris	80.07	2.00e-134	471.00
IUUC-Cpo-022147	Cavia porcellus	82.21	1.00e-135	474.00
IUUC-Csa-023473	Chlorocebus sabaeus	81.85	4.00e-137	480.00
IUUC-Cho-024298	Choloepus hoffmanni	79.77	7.00e-124	435.00
IUUC-Dre-028099	Danio rerio	62.99	5.00e-85	306.00
IUUC-Dno-029122	Dasypus novemcinctus	77.30	4.00e-126	443.00
IUUC-Dor-030669	Dipodomys ordii	84.83	3.00e-107	380.00
IUUC-Ete-033141	Echinops telfairi	69.04	3.00e-100	357.00
IUUC-Eca-034360	Equus caballus	83.63	7.00e-140	489.00
IUUC-Eeu-034538	Erinaceus europaeus	64.92	1.00e-67	248.00
IUUC-Fca-036055	Felis catus	80.07	7.00e-134	469.00
IUUC-Fal-037339	Ficedula albicollis	90.32	7.00e-150	522.00
IUUC-Gmo-038780	Gadus morhua	58.00	7.00e-81	293.00
IUUC-Gga-040256	Gallus gallus	93.95	2.00e-155	541.00
IUUC-Gac-042127	Gasterosteus aculeatus	60.53	2.00e-84	305.00
IUUC-Ggo-044867	Gorilla gorilla	82.21	4.00e-137	479.00
IUUC-Hsa-046928	Homo sapiens	81.85	1.00e-136	478.00
IUUC-Hvu-047484	Hordeum vulgare	31.55	7.00e-19	88.20
IUUC-Itr-048250	Ictidomys tridecemlineatus	81.87	7.00e-84	302.00
IUUC-Lch-050168	Latimeria chalumnae	74.91	2.00e-125	441.00
IUUC-Lpe-051649	Leersia perrieri	29.13	1.00e-18	88.20
IUUC-Loc-052150	Lepisosteus oculatus	61.45	2.00e-87	315.00
IUUC-Laf-053967	Loxodonta africana	81.49	2.00e-138	484.00
IUUC-Mcc-055898	Macaca mulatta	81.85	4.00e-137	480.00
IUUC-Meu-056628	Macropus eugenii	92.31	2.00e-42	165.00
IUUC-Mtr-058227	Medicago truncatula	27.16	8.00e-19	87.00
IUUC-Mga-059820	Meleagris gallopavo	93.24	1.00e-153	535.00
IUUC-Mmr-060680	Microcebus murinus	81.91	1.00e-135	475.00
IUUC-Mdo-062839	Monodelphis domestica	79.08	3.00e-133	467.00
IUUC-Mmu-063339	Mus musculus	79.41	7.00e-120	422.00
IUUC-Mac-065414	Musa acuminata	29.11	1.00e-19	89.70
IUUC-Mpu-065973	Mustela putorius furo	79.00	1.00e-133	469.00
IUUC-Mlu-067112	Myotis lucifugus	80.43	2.00e-135	474.00
IUUC-Nle-069795	Nomascus leucogenys	81.85	8.00e-137	479.00
IUUC-Opr-070390	Ochotona princeps	79.38	6.00e-122	429.00
IUUC-Ont-072329	Oreochromis niloticus	63.64	1.00e-87	315.00
IUUC-Oan-072980	Ornithorhynchus anatinus	74.13	8.00e-123	432.00
IUUC-Ocu-073845	Oryctolagus cuniculus	81.49	6.00e-136	476.00
IUUC-Ola-086872	Oryzias latipes	58.61	1.00e-81	295.00
IUUC-Oga-088954	Otolemur garnettii	81.14	4.00e-136	476.00
IUUC-Oar-089879	Ovis aries	82.27	3.00e-136	477.00
IUUC-Ptr-090685	Pan troglodytes	81.85	1.00e-136	478.00
IUUC-Pan-092086	Papio anubis	82.21	3.00e-137	480.00
IUUC-Psi-093481	Pelodiscus sinensis	84.34	5.00e-132	463.00
IUUC-Pfo-096065	Poecilia formosa	63.49	1.00e-84	305.00
IUUC-Pab-098031	Pongo abelii	82.21	2.00e-137	481.00
IUUC-Pop-099816	Populus trichocarpa	27.78	5.00e-18	85.10
IUUC-Pca-100936	Procavia capensis	81.85	6.00e-138	482.00
IUUC-Pva-102864	Pteropus vampyrus	69.40	1.00e-111	395.00
IUUC-Rno-105503	Rattus norvegicus	79.78	1.00e-120	425.00
IUUC-Sha-107425	Sarcophilus harrisii	80.85	1.00e-135	474.00
IUUC-Stu-112736	Solanum tuberosum	28.77	2.00e-20	92.00
IUUC-Ssc-115458	Sus scrofa	81.75	2.00e-136	478.00
IUUC-Tgu-117226	Taeniopygia guttata	91.04	5.00e-151	526.00
IUUC-Tru-118362	Takifugu rubripes	59.71	1.00e-85	308.00
IUUC-Tsy-119255	Tarsius syrichta	82.21	3.00e-137	480.00
IUUC-Tni-120140	Tetraodon nigroviridis	60.47	5.00e-81	293.00
IUUC-Tae-124420	Triticum aestivum	32.34	1.00e-19	91.30
IUUC-Tbe-127306	Tupaia belangeri	82.21	6.00e-137	479.00
IUUC-Ttr-128923	Tursiops truncatus	81.91	3.00e-135	474.00
IUUC-Vpa-130148	Vicugna pacos	82.92	1.00e-137	482.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence