iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000009894.1	ENSLOCT00000012132.1	ENSLOCP00000012111.1
ENSLOCG00000009894.1	ENSLOCT00000012144.1	ENSLOCP00000012123.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.60e-22	77.7	620	658
UBD/Beta-Prp	2.80e-40	138.5	488	657

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gHtd+ +c++  +d t l++G+ D+t++ WDlr+g++l+
   Q: 620  GHTDGASCIDIsNDgTKLWTGGLDNTVRSWDLREGRQLQ 658
           8***********999*********************998 PP

UBD/Beta-Prp

   S: 50   gheaevtavkfspdgkilvtgseDrtikvwdls...tgkcvhtlk..ghedsvlslsfspsgdklvsGshdrtirvwdletgqclee.t 132
           +h + v av++s+ +   v ++  + +kvwd+s   + ++v+ l   + +++++s+++ p+g +l++G++ +t+ +wdl   +   +  
   Q: 488  SHGEVVCAVTISNPTR-HVYTGGKGCVKVWDIShpgNKSPVSQLDclNRDNYIRSCRLLPDGRTLIVGGEASTLSIWDLAAPTPRIKaE 575
           4555788899999985.555555579*******999888999988889*******************************9988766658 PP
   S: 133  lsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecv 215
           l+    +   ++++pd+++++s++ D+ + +Wdl +++l+r+++g htd   +++++ +g+ l +g+ld+tv+ wdl++g+ +
   Q: 576  LTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQG-HTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQL 657
           88888888999*********************************9.********************************99754 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MIRDLSKMYP QARHPAPHQP AQPFKFTISE SCDRIKEEFQ FLQAQYHSLK LECEKLASEK 60
TEMQRHYVMY YEMSYGLNIE MHKQAEIVKR LNAICAQVIP FLSQEHQQQV VQAVERAKQV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTCCGCCTC GAAGCCCGTT GCCTCGCCTT GGGACTATTC GCGAAGCCAT AAGGAAAATG 60
TAGTTAAAAG AAAGATGGAC TTGCTTTGAA AATCTCAGGA TGGAACTTGC CCAGAGACTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR005617--Groucho/TLE_N
IPR009146--Groucho_enhance
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF03920--TLE_N
PF00400--WD40

PRINTS

PR01850--GROUCHOFAMLY

SMART

SM00320--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0006355--P:regulation of transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-005279	Anolis carolinensis	96.01	0.00e+00	1302.00
IUUC-Bta-012646	Bos taurus	94.33	0.00e+00	1322.00
IUUC-Cel-018361	Caenorhabditis elegans	58.43	4.00e-121	428.00
IUUC-Cja-019079	Callithrix jacchus	95.62	0.00e+00	1355.00
IUUC-Cfa-020987	Canis familiaris	95.22	0.00e+00	1300.00
IUUC-Cpo-021606	Cavia porcellus	93.36	0.00e+00	1285.00
IUUC-Csa-023445	Chlorocebus sabaeus	95.62	0.00e+00	1328.00
IUUC-Cho-024590	Choloepus hoffmanni	82.53	0.00e+00	1163.00
IUUC-Dno-028979	Dasypus novemcinctus	95.28	0.00e+00	1279.00
IUUC-Dor-030533	Dipodomys ordii	89.23	0.00e+00	1113.00
IUUC-Dme-031576	Drosophila melanogaster	86.59	0.00e+00	666.00
IUUC-Ete-032887	Echinops telfairi	82.93	0.00e+00	1178.00
IUUC-Eca-034397	Equus caballus	94.24	0.00e+00	1219.00
IUUC-Eeu-035237	Erinaceus europaeus	81.42	0.00e+00	1103.00
IUUC-Fca-036030	Felis catus	95.66	0.00e+00	1328.00
IUUC-Fal-037460	Ficedula albicollis	95.66	0.00e+00	1306.00
IUUC-Gga-040416	Gallus gallus	95.88	0.00e+00	1333.00
IUUC-Ggo-045633	Gorilla gorilla	91.80	0.00e+00	1299.00
IUUC-Hsa-046461	Homo sapiens	91.71	0.00e+00	1326.00
IUUC-Itr-048974	Ictidomys tridecemlineatus	95.75	0.00e+00	1335.00
IUUC-Lch-049943	Latimeria chalumnae	94.66	0.00e+00	1223.00
IUUC-Laf-053425	Loxodonta africana	95.80	0.00e+00	1325.00
IUUC-Mcc-055766	Macaca mulatta	91.83	0.00e+00	1328.00
IUUC-Meu-056209	Macropus eugenii	91.07	0.00e+00	1321.00
IUUC-Mmr-061317	Microcebus murinus	92.29	0.00e+00	1329.00
IUUC-Mdo-062956	Monodelphis domestica	96.01	0.00e+00	1338.00
IUUC-Mmu-063576	Mus musculus	95.49	0.00e+00	1322.00
IUUC-Mpu-066410	Mustela putorius furo	95.38	0.00e+00	1224.00
IUUC-Mlu-067456	Myotis lucifugus	93.84	0.00e+00	1255.00
IUUC-Nle-069495	Nomascus leucogenys	95.66	0.00e+00	1298.00
IUUC-Ont-071419	Oreochromis niloticus	87.39	0.00e+00	1208.00
IUUC-Oan-072842	Ornithorhynchus anatinus	93.10	0.00e+00	1316.00
IUUC-Ocu-074453	Oryctolagus cuniculus	94.20	0.00e+00	1305.00
IUUC-Ola-087090	Oryzias latipes	86.74	0.00e+00	1204.00
IUUC-Oga-087939	Otolemur garnettii	95.88	0.00e+00	1336.00
IUUC-Oar-090347	Ovis aries	94.26	0.00e+00	1206.00
IUUC-Ptr-091048	Pan troglodytes	95.62	0.00e+00	1328.00
IUUC-Pan-091973	Papio anubis	90.98	0.00e+00	1274.00
IUUC-Pfo-097518	Poecilia formosa	85.75	0.00e+00	1152.00
IUUC-Pva-103037	Pteropus vampyrus	89.84	0.00e+00	1320.00
IUUC-Rno-105314	Rattus norvegicus	95.28	0.00e+00	1254.00
IUUC-Ssc-116408	Sus scrofa	95.25	0.00e+00	1350.00
IUUC-Tgu-117068	Taeniopygia guttata	95.35	0.00e+00	1311.00
IUUC-Tru-118782	Takifugu rubripes	83.50	0.00e+00	1138.00
IUUC-Tsy-118884	Tarsius syrichta	81.82	0.00e+00	1049.00
IUUC-Tni-120404	Tetraodon nigroviridis	85.02	0.00e+00	1195.00
IUUC-Tbe-128013	Tupaia belangeri	87.72	0.00e+00	1221.00
IUUC-Ttr-129285	Tursiops truncatus	90.67	0.00e+00	1315.00
IUUC-Vpa-130577	Vicugna pacos	85.48	0.00e+00	669.00
IUUC-Xtr-132974	Xenopus tropicalis	93.21	0.00e+00	1261.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence