iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ola-087090

Ensembl Protein ID

ENSORLP00000002066.1

UniProt Accession

H2L896; H2L896_ORYLA

Genbank Protein ID

ENSORLP00000002066

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

BAAF04041657

Gene Name

TLE4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSORLG00000001664.1	ENSORLT00000002067.1	ENSORLP00000002066.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.10e-22	78.5	614	652
UBD/Beta-Prp	2.90e-40	138.6	482	651

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gHtd+ +c++  +d t l++G+ D+t++ WDlr+g++l+
   Q: 614  GHTDGASCIDIsNDgTKLWTGGLDNTVRSWDLREGRQLQ 652
           8***********999*********************998 PP

UBD/Beta-Prp

   S: 50   gheaevtavkfspdgkilvtgseDrtikvwdls...tgkcvhtlk..ghedsvlslsfspsgdklvsGshdrtirvwdletgqclee.t 132
           +h + v av++s+ +   v ++  + +kvwd+s   + ++v+ l   + +++++s+++ p+g +l++G++ +t+ +wdl t +   +  
   Q: 482  SHGEVVCAVTISNPTR-HVYTGGKGCVKVWDIShpgNKTPVSQLDclNRDNYIRSCRLLPDGRTLIVGGEASTLSIWDLATPTPRIKaE 569
           4555788899999985.555555579*******999888888888889*********************************99877658 PP
   S: 133  lsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecv 215
           l+    +   ++++pd+++++s++ D+ + +Wdl +++l+r+++g htd   +++++ +g+ l +g+ld+tv+ wdl++g+ +
   Q: 570  LTSSAPACYALAISPDSKVCFSCCSDGNIAVWDLHNQTLVRQFQG-HTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQL 651
           888888888999********************************9.********************************99754 PP

Organism

Oryzias latipes

Protein Sequence
(Fasta)

MIRDLSKMYP PARHPVPHQP GQPFKFTVTE SCDRIKEEFQ FLQAQYHSLK MECEKLASEK 60
TEMQRHYVMY YEMSYGLNIE MHKQAEIVKR LNAICAQVIP FLSQEHQQQV VQAVERAKQV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGATTCGAG ATCTGAGCAA GATGTACCCC CCGGCCCGGC ATCCGGTAAG TAGATGTCAT 60
CGAGGGTCAA CTTGTCAAAA CGGCGCAGAT TTAACAGCCG CGAGCCTGAT GCGTAATCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR005617--Groucho/TLE_N
IPR009146--Groucho_enhance
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF03920--TLE_N
PF00400--WD40

PRINTS

PR01850--GROUCHOFAMLY

SMART

SM00320--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0006355--P:regulation of transcription, DNA-templated

KEGG

ola:100125464

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-005279	Anolis carolinensis	88.40	0.00e+00	1192.00
IUUC-Bta-012646	Bos taurus	87.13	0.00e+00	1201.00
IUUC-Cel-018361	Caenorhabditis elegans	58.43	9.00e-121	427.00
IUUC-Cja-019079	Callithrix jacchus	87.76	0.00e+00	1237.00
IUUC-Cfa-020987	Canis familiaris	88.05	0.00e+00	1196.00
IUUC-Cpo-021606	Cavia porcellus	86.31	0.00e+00	1169.00
IUUC-Csa-023445	Chlorocebus sabaeus	88.02	0.00e+00	1219.00
IUUC-Cho-024590	Choloepus hoffmanni	75.96	0.00e+00	1058.00
IUUC-Cin-025767	Ciona intestinalis	59.14	2.00e-174	605.00
IUUC-Csv-026174	Ciona savignyi	58.28	3.00e-166	578.00
IUUC-Dno-028979	Dasypus novemcinctus	87.47	0.00e+00	1163.00
IUUC-Dor-030533	Dipodomys ordii	82.87	0.00e+00	1027.00
IUUC-Ete-032887	Echinops telfairi	76.23	0.00e+00	1072.00
IUUC-Eca-034397	Equus caballus	87.65	0.00e+00	1117.00
IUUC-Eeu-035237	Erinaceus europaeus	76.68	0.00e+00	999.00
IUUC-Fca-036030	Felis catus	87.80	0.00e+00	1203.00
IUUC-Fal-037460	Ficedula albicollis	87.91	0.00e+00	1192.00
IUUC-Gga-040416	Gallus gallus	88.14	0.00e+00	1220.00
IUUC-Gac-041739	Gasterosteus aculeatus	82.81	0.00e+00	1137.00
IUUC-Ggo-045633	Gorilla gorilla	84.49	0.00e+00	1190.00
IUUC-Hsa-046461	Homo sapiens	84.53	0.00e+00	1216.00
IUUC-Itr-048974	Ictidomys tridecemlineatus	87.90	0.00e+00	1215.00
IUUC-Lch-049943	Latimeria chalumnae	86.85	0.00e+00	1139.00
IUUC-Loc-052835	Lepisosteus oculatus	89.06	0.00e+00	1187.00
IUUC-Laf-053425	Loxodonta africana	88.17	0.00e+00	1211.00
IUUC-Mcc-055766	Macaca mulatta	84.53	0.00e+00	1216.00
IUUC-Meu-056209	Macropus eugenii	83.50	0.00e+00	1200.00
IUUC-Mmr-061317	Microcebus murinus	84.95	0.00e+00	1218.00
IUUC-Mdo-062956	Monodelphis domestica	87.77	0.00e+00	1206.00
IUUC-Mmu-063576	Mus musculus	87.89	0.00e+00	1212.00
IUUC-Mlu-067456	Myotis lucifugus	84.74	0.00e+00	1138.00
IUUC-Nle-069495	Nomascus leucogenys	88.04	0.00e+00	1190.00
IUUC-Ont-071419	Oreochromis niloticus	96.24	0.00e+00	1262.00
IUUC-Oan-072842	Ornithorhynchus anatinus	85.57	0.00e+00	1200.00
IUUC-Ocu-074453	Oryctolagus cuniculus	87.11	0.00e+00	1201.00
IUUC-Oga-087939	Otolemur garnettii	88.03	0.00e+00	1216.00
IUUC-Ptr-091048	Pan troglodytes	88.02	0.00e+00	1219.00
IUUC-Pan-091973	Papio anubis	83.38	0.00e+00	1164.00
IUUC-Pfo-097518	Poecilia formosa	94.19	0.00e+00	1206.00
IUUC-Pva-103037	Pteropus vampyrus	81.41	0.00e+00	1203.00
IUUC-Rno-105314	Rattus norvegicus	87.45	0.00e+00	1144.00
IUUC-Ssc-116408	Sus scrofa	87.56	0.00e+00	1224.00
IUUC-Tgu-117068	Taeniopygia guttata	87.80	0.00e+00	1185.00
IUUC-Tru-118782	Takifugu rubripes	89.85	0.00e+00	1168.00
IUUC-Tsy-118884	Tarsius syrichta	75.98	0.00e+00	965.00
IUUC-Tni-120404	Tetraodon nigroviridis	88.52	0.00e+00	1207.00
IUUC-Tbe-128013	Tupaia belangeri	80.51	0.00e+00	1112.00
IUUC-Ttr-129285	Tursiops truncatus	83.35	0.00e+00	1199.00
IUUC-Vpa-130577	Vicugna pacos	73.65	6.00e-158	551.00
IUUC-Xtr-132974	Xenopus tropicalis	86.28	0.00e+00	1161.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence