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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Rno-105314
Ensembl Protein ID ENSRNOP00000074268.1
UniProt Accession A0A0G2K7M5; A0A0G2K7M5_RAT
Genbank Protein ID ENSRNOP00000074268
Protein Name Transducin-like enhancer protein 4
Genbank Nucleotide ID AABR07006367
Gene Name Tle4
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSRNOG00000013239.8 ENSRNOT00000087140.1 ENSRNOP00000074268.1
ENSRNOG00000013239.8 ENSRNOT00000018452.6 ENSRNOP00000018452.6
ENSRNOG00000013239.8 ENSRNOT00000018272.8 ENSRNOP00000018272.7
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
DNA & RNA Element
microRNATRANSFACRAID2
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.80e-19 69.4 617 655
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gHtd+ +c++  +d t l++G+ D+t++ WDlr+g++l+
   Q: 617  GHTDGASCIDIsNDgTKLWTGGLDNTVRSWDLREGRQLQ 655
           8***********999*********************998 PP
   
Organism Rattus norvegicus
Protein Sequence
(Fasta)
MIRDLSKMYP QTRHPAPHQP AQPFKFTISE SCDRIKEEFQ FLQAQYHSLK LECEKLASEK 60
TEMQRHYVMY YEMSYGLNIE MHKQAEIVKR LNAICAQVIP FLSQEHQQQV VQAVERAKQV 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Rno-105314|E3,WD_repeat|Rattus norvegicus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CGCCGCCCTC AGTGACGCCC GCGGGGAATG CGGAGCCGGC CGCCCGCGCT CAGCCGCCGC 60
GCCTGCCTGC CGCCCGCGTC ACGCGAGACC CGCAGGCCCG GGACGCCGCC GCGGGGCCCT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Rno-105314|E3,WD_repeat|Rattus norvegicus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat
Interpro

IPR005617--Groucho/TLE_N
IPR009146--Groucho_enhance
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF03920--TLE_N
PF00400--WD40
PRINTS

PR01850--GROUCHOFAMLY
SMART

SM00320--WD40
Gene Ontology

GO:0005634--C:nucleus
GO:0003682--F:chromatin binding
GO:0003714--F:transcription corepressor activity
GO:0003705--F:transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0016055--P:Wnt signaling pathway
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Apl-003434 Anas platyrhynchos 87.61 0.00e+00 1068.00
IUUC-Aca-005279 Anolis carolinensis 98.92 0.00e+00 1267.00
IUUC-Bta-012646 Bos taurus 98.65 0.00e+00 1295.00
IUUC-Cja-019079 Callithrix jacchus 99.32 0.00e+00 1339.00
IUUC-Cfa-020987 Canis familiaris 99.02 0.00e+00 1285.00
IUUC-Cpo-021606 Cavia porcellus 97.13 0.00e+00 1252.00
IUUC-Csa-023445 Chlorocebus sabaeus 99.73 0.00e+00 1312.00
IUUC-Cho-024590 Choloepus hoffmanni 84.79 0.00e+00 1143.00
IUUC-Dno-028979 Dasypus novemcinctus 98.92 0.00e+00 1335.00
IUUC-Dor-030533 Dipodomys ordii 94.61 0.00e+00 1093.00
IUUC-Ete-032887 Echinops telfairi 85.92 0.00e+00 1164.00
IUUC-Eca-034397 Equus caballus 99.13 0.00e+00 1204.00
IUUC-Eeu-035237 Erinaceus europaeus 88.92 0.00e+00 1118.00
IUUC-Fca-036030 Felis catus 99.17 0.00e+00 1300.00
IUUC-Fal-037460 Ficedula albicollis 99.03 0.00e+00 1276.00
IUUC-Gga-040416 Gallus gallus 99.32 0.00e+00 1306.00
IUUC-Ggo-045633 Gorilla gorilla 95.36 0.00e+00 1278.00
IUUC-Hsa-046461 Homo sapiens 95.45 0.00e+00 1310.00
IUUC-Itr-048974 Ictidomys tridecemlineatus 99.59 0.00e+00 1308.00
IUUC-Lch-049943 Latimeria chalumnae 95.66 0.00e+00 1170.00
IUUC-Loc-052835 Lepisosteus oculatus 95.28 0.00e+00 1206.00
IUUC-Laf-053425 Loxodonta africana 99.59 0.00e+00 1308.00
IUUC-Mcc-055766 Macaca mulatta 95.58 0.00e+00 1313.00
IUUC-Mmr-061317 Microcebus murinus 96.08 0.00e+00 1313.00
IUUC-Mdo-062956 Monodelphis domestica 98.65 0.00e+00 1295.00
IUUC-Mmu-063576 Mus musculus 100.00 0.00e+00 1303.00
IUUC-Mpu-066410 Mustela putorius furo 99.41 0.00e+00 1208.00
IUUC-Mlu-067456 Myotis lucifugus 97.17 0.00e+00 1227.00
IUUC-Nle-069495 Nomascus leucogenys 99.72 0.00e+00 1280.00
IUUC-Ont-071419 Oreochromis niloticus 85.31 0.00e+00 1118.00
IUUC-Oan-072842 Ornithorhynchus anatinus 95.52 0.00e+00 1285.00
IUUC-Ocu-074453 Oryctolagus cuniculus 98.24 0.00e+00 1290.00
IUUC-Ola-087090 Oryzias latipes 84.89 0.00e+00 1127.00
IUUC-Oga-087939 Otolemur garnettii 99.46 0.00e+00 1305.00
IUUC-Oar-090347 Ovis aries 98.82 0.00e+00 1178.00
IUUC-Ptr-091048 Pan troglodytes 99.73 0.00e+00 1312.00
IUUC-Pan-091973 Papio anubis 94.85 0.00e+00 1258.00
IUUC-Pab-097539 Pongo abelii 95.20 0.00e+00 1182.00
IUUC-Pca-101137 Procavia capensis 87.61 0.00e+00 1072.00
IUUC-Pva-103037 Pteropus vampyrus 92.85 0.00e+00 1298.00
IUUC-Sar-113267 Sorex araneus 88.05 0.00e+00 729.00
IUUC-Ssc-116408 Sus scrofa 98.79 0.00e+00 1324.00
IUUC-Tgu-117068 Taeniopygia guttata 98.18 0.00e+00 1271.00
IUUC-Tru-118782 Takifugu rubripes 82.19 0.00e+00 1080.00
IUUC-Tsy-118884 Tarsius syrichta 85.26 0.00e+00 1016.00
IUUC-Tni-120404 Tetraodon nigroviridis 83.74 0.00e+00 1118.00
IUUC-Tbe-128013 Tupaia belangeri 91.09 0.00e+00 1205.00
IUUC-Vpa-130577 Vicugna pacos 90.40 0.00e+00 714.00
IUUC-Xtr-132974 Xenopus tropicalis 96.10 0.00e+00 1217.00
Created Date 25-Jun-2017

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