iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-054465

Ensembl Protein ID

ENSLAFP00000005302.2

UniProt Accession

G3SXY5; G3SXY5_LOXAF

Protein Name

Uncharacterized protein

Gene Name

PACSIN1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000006319.2	ENSLAFT00000006317.2	ENSLAFP00000005302.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	8.60e-14	51.6	390	444

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
           +v++lydy++q++deL++k+Gd ++ +  ee ++gW+ g + ++g+ Gl P+n+ve +
   Q: 390  RVRALYDYDGQEQDELSFKAGDELTKL-GEEDEQGWC-G-RLDSGQLGLYPANYVEAI 444
           699************************.*********.7.59*************975 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MSGSYDEASL AAEEITDSFW EVGNYKRTVK RIDDGHRLCN DLMSCVQERA KIEKAYAQQL 60
TDWAKRWRQL IEKGAPQYGS LERAWGAMMT EADKVSELHQ EVKNNLLNED LEKVKNWQKD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCCGGCT CCTACGATGA GGCATCGTTG GCTGCAGAGG AGATCACTGA CAGCTTCTGG 60
GAGGTGAGCC TTTGATGCAG AGGCTCCGGC TCCCACCCAC AGCTCACTAA CCCCAGGATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR031160--F_BAR
IPR001060--FCH_dom
IPR028518--PACSIN1
IPR001452--SH3_domain

PROSITE

PS51741--F_BAR
PS50002--SH3

Pfam

PF00611--FCH
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00055--FCH
SM00326--SH3

Gene Ontology

GO:0030137--C:COPI-coated vesicle
GO:0043209--C:myelin sheath
GO:0032587--C:ruffle membrane
GO:0045202--C:synapse
GO:0005543--F:phospholipid binding
GO:0007015--P:actin filament organization
GO:0045806--P:negative regulation of endocytosis
GO:0048666--P:neuron development
GO:0097320--P:plasma membrane tubulation
GO:0072657--P:protein localization to membrane
GO:0048488--P:synaptic vesicle endocytosis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001861	Ailuropoda melanoleuca	86.71	0.00e+00	757.00
IUUC-Apl-003667	Anas platyrhynchos	83.61	0.00e+00	674.00
IUUC-Aca-005229	Anolis carolinensis	82.33	0.00e+00	717.00
IUUC-Ame-011410	Astyanax mexicanus	73.38	2.00e-174	605.00
IUUC-Bta-013509	Bos taurus	93.48	0.00e+00	736.00
IUUC-Cja-019659	Callithrix jacchus	95.28	0.00e+00	804.00
IUUC-Cfa-020396	Canis familiaris	95.96	0.00e+00	782.00
IUUC-Cpo-022376	Cavia porcellus	94.83	0.00e+00	773.00
IUUC-Csa-023701	Chlorocebus sabaeus	94.83	0.00e+00	772.00
IUUC-Dre-027456	Danio rerio	74.11	0.00e+00	658.00
IUUC-Eca-033679	Equus caballus	89.06	0.00e+00	709.00
IUUC-Fca-036314	Felis catus	95.73	0.00e+00	781.00
IUUC-Fal-037300	Ficedula albicollis	83.67	0.00e+00	717.00
IUUC-Gmo-038571	Gadus morhua	67.77	1.00e-159	556.00
IUUC-Gga-040626	Gallus gallus	84.34	0.00e+00	673.00
IUUC-Gac-041445	Gasterosteus aculeatus	69.49	7.00e-165	573.00
IUUC-Ggo-045557	Gorilla gorilla	94.61	0.00e+00	771.00
IUUC-Hsa-045778	Homo sapiens	94.61	0.00e+00	771.00
IUUC-Itr-048856	Ictidomys tridecemlineatus	95.51	0.00e+00	779.00
IUUC-Lch-050070	Latimeria chalumnae	71.34	0.00e+00	657.00
IUUC-Loc-051764	Lepisosteus oculatus	78.97	0.00e+00	689.00
IUUC-Mcc-055324	Macaca mulatta	94.61	0.00e+00	773.00
IUUC-Meu-056348	Macropus eugenii	89.21	0.00e+00	728.00
IUUC-Mga-059285	Meleagris gallopavo	84.31	0.00e+00	658.00
IUUC-Mmr-061367	Microcebus murinus	96.40	0.00e+00	744.00
IUUC-Mdo-062432	Monodelphis domestica	57.37	1.00e-135	476.00
IUUC-Mmu-064347	Mus musculus	95.51	0.00e+00	820.00
IUUC-Mpu-066864	Mustela putorius furo	95.51	0.00e+00	778.00
IUUC-Nle-070027	Nomascus leucogenys	94.82	0.00e+00	732.00
IUUC-Ont-072188	Oreochromis niloticus	71.88	0.00e+00	626.00
IUUC-Ocu-074297	Oryctolagus cuniculus	94.83	0.00e+00	746.00
IUUC-Ola-087188	Oryzias latipes	71.88	3.00e-158	551.00
IUUC-Oga-088856	Otolemur garnettii	95.28	0.00e+00	752.00
IUUC-Oar-090278	Ovis aries	85.84	0.00e+00	631.00
IUUC-Pan-092056	Papio anubis	94.83	0.00e+00	772.00
IUUC-Pfo-097528	Poecilia formosa	69.64	1.00e-154	538.00
IUUC-Pab-098202	Pongo abelii	94.83	0.00e+00	773.00
IUUC-Pca-100881	Procavia capensis	95.28	0.00e+00	776.00
IUUC-Pva-102181	Pteropus vampyrus	94.16	0.00e+00	771.00
IUUC-Rno-105295	Rattus norvegicus	92.36	0.00e+00	763.00
IUUC-Sha-107163	Sarcophilus harrisii	75.57	0.00e+00	640.00
IUUC-Ssc-115685	Sus scrofa	94.38	0.00e+00	769.00
IUUC-Tgu-116524	Taeniopygia guttata	77.18	0.00e+00	633.00
IUUC-Tru-118248	Takifugu rubripes	69.42	7.00e-154	536.00
IUUC-Tni-120717	Tetraodon nigroviridis	70.31	1.00e-155	542.00
IUUC-Ttr-129069	Tursiops truncatus	95.05	0.00e+00	735.00
IUUC-Xtr-132759	Xenopus tropicalis	70.98	0.00e+00	637.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence