iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-034208

UUCD1 version

UUC-EqC-01042

Ensembl Protein ID

ENSECAP00000011479.1

UniProt Accession

F7BBB6; F7BBB6_HORSE

Protein Name

Uncharacterized protein

Gene Name

USP40

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000013493.1	ENSECAT00000014364.1	ENSECAP00000011479.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.60e-79	267.0	42	481

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkg....ellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           G++N+g tCY+NS+LQ+L+++pe+re+l++  +e+l   ++k++       +  +lq+lf++l+  +++a s+ +l+++++++++e  +
   Q: 42   GIRNQGGTCYLNSLLQTLHFTPEFREALFSLGPEELGSLEDKDKPDakvrIIPLELQRLFAQLLLLDQEAASTADLTDSFGWTSNE--E 128
           9*****************************777777665543332234458899******************************98..* PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslp 175
           ++q+D+qE+ ++l+++le++l                            +++++li++l++g++ +qi+c+ec+nvs+++e+fldl+++
   Q: 129  MRQHDVQELNRILFSALETSL--------------------------VGTSGHDLINRLYHGTIVNQIVCKECKNVSEKQEDFLDLTVA 191
           *********************..........................789*************************************** PP
   S: 176  vpgkeetkkeslqdcL.esftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlsp 263
           v++ +      l+d+L +++++ee ++++n y+c +c+++++a k+ kl+klP++L++ L Rf+f+  ++ r k +++++fpl+++l+p
   Q: 192  VKNVS-----GLEDALwNMYVEEEIFDSDNLYHCGTCDRLVKAAKSAKLRKLPPFLTVSLLRFNFDFVKCERYKETSCYTFPLRINLKP 275
           *****.....9*****9************************************************************************ PP
   S: 264  fctspeekqkekkkYeLiavvvHsGslssGHYvayvkn................................................... 301
           fc+++e ++  ++ Y+L++v++H+G++ +GHY++y+k+                                                   
   Q: 276  FCEQSELDDL-EYVYDLFSVIIHKGGCYGGHYHVYIKDvdhlgnwqfqeenskpdvnlkdlqneeeiddplmilktillqesnllpvdq 363
           ****999987.9***************************************************************************** PP
   S: 302  .............................................................................ekgk.....Wll 308
                                                                                           +     W+ 
   Q: 364  lgqkllkkigiswnkkyrkqygplrkflqlhsqtfllssdestvrllknstlqaepdfqrndqqifktlpsespgfnG--RtscphWFD 450
           *******************************************************99999999999999988887551..245678*** PP
   S: 309  fdDskVtevkeeevleetg..staYvlfYkr 337
           ++DskV+++ke++++++ +  ++aY+lfY++
   Q: 451  INDSKVQPIKEKDIQQQFQgkESAYMLFYRK 481
           ****************9889*********98 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MFGDLFEEDD SSVSHNQYGK GKKLKTKAVE PPPPREFTNL SGIRNQGGTC YLNSLLQTLH 60
FTPEFREALF SLGPEELGSL EDKDKPDAKV RIIPLELQRL FAQLLLLDQE AASTADLTDS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCTTTTT CTTTAAGGGT AGTATTTAGT TTCACAATGT TTGGGGACCT ATTTGAAGAG 60
GATGATTCCA GTGTGTCACA TAATCAGTAT GGAAAAGGGA AGAAATTAAA GACCAAAGCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001216	Ailuropoda melanoleuca	85.27	0.00e+00	1991.00
IUUC-Apl-004105	Anas platyrhynchos	64.61	0.00e+00	1568.00
IUUC-Aca-004715	Anolis carolinensis	63.18	0.00e+00	1512.00
IUUC-Ame-011073	Astyanax mexicanus	47.62	0.00e+00	1034.00
IUUC-Bta-012487	Bos taurus	86.41	0.00e+00	2094.00
IUUC-Cja-018937	Callithrix jacchus	85.29	0.00e+00	2097.00
IUUC-Cfa-020645	Canis familiaris	81.88	0.00e+00	1308.00
IUUC-Cpo-022160	Cavia porcellus	79.08	0.00e+00	1949.00
IUUC-Csa-023078	Chlorocebus sabaeus	84.79	0.00e+00	2126.00
IUUC-Cho-025013	Choloepus hoffmanni	67.51	0.00e+00	841.00
IUUC-Csv-026193	Ciona savignyi	56.47	5.00e-60	223.00
IUUC-Dre-027416	Danio rerio	49.45	0.00e+00	1147.00
IUUC-Dno-029639	Dasypus novemcinctus	81.59	0.00e+00	1721.00
IUUC-Dor-030624	Dipodomys ordii	90.67	8.00e-156	544.00
IUUC-Ete-032626	Echinops telfairi	66.27	0.00e+00	792.00
IUUC-Eeu-035340	Erinaceus europaeus	48.18	4.00e-95	342.00
IUUC-Fca-035886	Felis catus	78.53	0.00e+00	837.00
IUUC-Fal-036925	Ficedula albicollis	64.65	0.00e+00	1467.00
IUUC-Gmo-038597	Gadus morhua	45.43	0.00e+00	889.00
IUUC-Gga-041171	Gallus gallus	64.29	0.00e+00	1550.00
IUUC-Gac-041362	Gasterosteus aculeatus	46.51	0.00e+00	969.00
IUUC-Ggo-045069	Gorilla gorilla	84.36	0.00e+00	1941.00
IUUC-Hsa-046715	Homo sapiens	86.40	0.00e+00	2144.00
IUUC-Itr-049006	Ictidomys tridecemlineatus	81.05	0.00e+00	1954.00
IUUC-Lch-050182	Latimeria chalumnae	52.77	0.00e+00	1180.00
IUUC-Loc-052705	Lepisosteus oculatus	54.27	0.00e+00	1279.00
IUUC-Laf-054132	Loxodonta africana	83.10	0.00e+00	2072.00
IUUC-Mcc-055734	Macaca mulatta	85.26	0.00e+00	2135.00
IUUC-Meu-056135	Macropus eugenii	85.41	1.00e-114	407.00
IUUC-Mga-060092	Meleagris gallopavo	63.94	0.00e+00	1526.00
IUUC-Mmr-061546	Microcebus murinus	82.32	0.00e+00	2006.00
IUUC-Mdo-061935	Monodelphis domestica	62.85	0.00e+00	1541.00
IUUC-Mmu-063630	Mus musculus	79.47	0.00e+00	1967.00
IUUC-Mpu-066579	Mustela putorius furo	83.27	0.00e+00	2071.00
IUUC-Mlu-068034	Myotis lucifugus	86.50	0.00e+00	2068.00
IUUC-Nle-069082	Nomascus leucogenys	83.53	0.00e+00	1755.00
IUUC-Opr-070953	Ochotona princeps	70.90	0.00e+00	991.00
IUUC-Ont-072435	Oreochromis niloticus	47.81	0.00e+00	1103.00
IUUC-Oan-073339	Ornithorhynchus anatinus	66.83	0.00e+00	1578.00
IUUC-Ocu-073760	Oryctolagus cuniculus	81.47	0.00e+00	2017.00
IUUC-Ola-087015	Oryzias latipes	47.45	0.00e+00	946.00
IUUC-Oga-088960	Otolemur garnettii	83.83	0.00e+00	2066.00
IUUC-Oar-089853	Ovis aries	87.24	0.00e+00	2133.00
IUUC-Ptr-091093	Pan troglodytes	85.99	0.00e+00	2136.00
IUUC-Pan-091962	Papio anubis	83.83	0.00e+00	2099.00
IUUC-Psi-093691	Pelodiscus sinensis	67.09	0.00e+00	1635.00
IUUC-Pma-094428	Petromyzon marinus	64.75	2.00e-92	331.00
IUUC-Pfo-096983	Poecilia formosa	47.83	0.00e+00	1032.00
IUUC-Pab-097860	Pongo abelii	85.08	0.00e+00	1972.00
IUUC-Pca-100514	Procavia capensis	78.38	0.00e+00	652.00
IUUC-Pva-102771	Pteropus vampyrus	86.14	0.00e+00	1999.00
IUUC-Rno-105405	Rattus norvegicus	78.50	0.00e+00	1918.00
IUUC-Sha-107376	Sarcophilus harrisii	64.66	0.00e+00	1488.00
IUUC-Ssc-115819	Sus scrofa	81.92	0.00e+00	1457.00
IUUC-Tgu-117262	Taeniopygia guttata	63.58	0.00e+00	1536.00
IUUC-Tru-117601	Takifugu rubripes	47.47	0.00e+00	1094.00
IUUC-Tsy-118996	Tarsius syrichta	74.46	0.00e+00	1654.00
IUUC-Tni-120682	Tetraodon nigroviridis	43.56	0.00e+00	882.00
IUUC-Tbe-127616	Tupaia belangeri	63.00	0.00e+00	1245.00
IUUC-Ttr-129075	Tursiops truncatus	84.66	0.00e+00	1991.00
IUUC-Vpa-130108	Vicugna pacos	87.44	0.00e+00	1919.00
IUUC-Xtr-132623	Xenopus tropicalis	52.36	0.00e+00	1208.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence