iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003360

Ensembl Protein ID

ENSAPLP00000008604.1

UniProt Accession

U3IMY1; U3IMY1_ANAPL

Genbank Protein ID

ENSAPLP00000008604

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01130482

Gene Name

EML5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000008892.1	ENSAPLT00000009286.1	ENSAPLP00000008604.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.40e-58	191.9	706	744
UBD/Beta-Prp	6.20e-124	412.7	661	875

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGs..dDgtikvWDlrtgvll 36
           H+ +v++++f  d ++l+s +  d++ti +WD+++g +l
   Q: 706  HQYGVCAVDFsADgKRLASVGidDNHTIVLWDWKKGEKL 744
           8899*******666*******866699******999875 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatg..srdgtikvwdvttgkllrsl.sgheaevtavkfspdgkilvtgseD..rtikvwdlstgkcvhtlkg 92
           h++ i c++++p k+++atg  +rd++i +wd++t k l+ l   h+ +v av+fs dgk l++++ D  +ti +wd ++g+ +++++g
   Q: 661  HDDDILCLAIHPLKDYVATGqvGRDSSIHIWDTETIKPLSVLkGYHQYGVCAVDFSADGKRLASVGIDdnHTIVLWDWKKGEKLSAVRG 749
           4555566************96669******************5559******************9999999****************** PP
   S: 93   hedsvlslsfspsgdklvsGshdrtirvwdletgqclee....tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltg 177
            +d++  ++++p+   ++++   + ++ w    g  +         g++++ +c+v+  ++ + +sG+  + v +W  +  +l++t + 
   Q: 750  SKDKIFVVKINPYMPEKLITVGIKHLKFWRRAGGGLIGRkgciGAMGRTDTMMCAVYGWTEEMAFSGTSTGDVCIW--RDVFLIKTVKA 836
           ************9987788888*******87777777668887899******************************..889******98 PP
   S: 178  ghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtln 219
            h+++v s+   +  k +v+g++dg v lwd   ++c++t+ 
   Q: 837  -HDGPVFSMHALE--KGFVTGGKDGVVALWDDTFERCLKTYA 875
           .********9888..67**********************996 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

SLALHPERVL VATGQVGKEP YICVWDSYTV QTVSVLKDVH THGIACLAFD LDGQRLVSVG 60
LDSKNTVCVW DWRKGKLLSM APGHTDRIFD ISWDLYQPNK LVSCGVKHIK FWSLCGNSLT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGCCTTGCTT TGCATCCTGA ACGTGTGCTG GTGGCAACAG GTCAAGTCGG AAAAGAACCG 60
TATATCTGTG TGTGGGACTC GTACACTGTG CAAACTGTAT CCGTTCTGAA AGATGTTCAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR005108--HELP
IPR011044--Quino_amine_DH_bsu
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0070062--C:extracellular exosome

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002225	Ailuropoda melanoleuca	90.91	0.00e+00	3583.00
IUUC-Ame-011681	Astyanax mexicanus	87.68	0.00e+00	3470.00
IUUC-Bta-012838	Bos taurus	90.61	0.00e+00	3570.00
IUUC-Cja-019068	Callithrix jacchus	90.91	0.00e+00	3561.00
IUUC-Cfa-020531	Canis familiaris	91.40	0.00e+00	3621.00
IUUC-Cpo-022304	Cavia porcellus	88.61	0.00e+00	3484.00
IUUC-Csa-023621	Chlorocebus sabaeus	90.99	0.00e+00	3382.00
IUUC-Cho-024944	Choloepus hoffmanni	72.37	0.00e+00	1427.00
IUUC-Dre-028772	Danio rerio	87.28	0.00e+00	3467.00
IUUC-Dno-030063	Dasypus novemcinctus	90.26	0.00e+00	3532.00
IUUC-Dor-030980	Dipodomys ordii	82.13	0.00e+00	1524.00
IUUC-Ete-032554	Echinops telfairi	90.70	0.00e+00	1030.00
IUUC-Eca-033909	Equus caballus	91.08	0.00e+00	3418.00
IUUC-Eeu-035180	Erinaceus europaeus	75.16	0.00e+00	1405.00
IUUC-Fal-037219	Ficedula albicollis	99.21	0.00e+00	3788.00
IUUC-Gmo-039146	Gadus morhua	82.92	0.00e+00	3278.00
IUUC-Gga-041095	Gallus gallus	99.49	0.00e+00	2689.00
IUUC-Gac-041341	Gasterosteus aculeatus	85.55	0.00e+00	3357.00
IUUC-Hsa-045997	Homo sapiens	91.17	0.00e+00	3570.00
IUUC-Lch-050306	Latimeria chalumnae	87.20	0.00e+00	3267.00
IUUC-Loc-052215	Lepisosteus oculatus	87.97	0.00e+00	3521.00
IUUC-Laf-054044	Loxodonta africana	89.57	0.00e+00	3534.00
IUUC-Mcc-054733	Macaca mulatta	91.17	0.00e+00	3564.00
IUUC-Meu-055977	Macropus eugenii	89.05	0.00e+00	926.00
IUUC-Mga-059666	Meleagris gallopavo	97.39	0.00e+00	3716.00
IUUC-Mmr-060995	Microcebus murinus	91.32	0.00e+00	3565.00
IUUC-Mdo-062482	Monodelphis domestica	92.42	0.00e+00	3629.00
IUUC-Mmu-063533	Mus musculus	90.03	0.00e+00	3511.00
IUUC-Mpu-066704	Mustela putorius furo	90.70	0.00e+00	3577.00
IUUC-Mlu-067592	Myotis lucifugus	90.34	0.00e+00	3542.00
IUUC-Nle-069911	Nomascus leucogenys	91.22	0.00e+00	3569.00
IUUC-Ont-071966	Oreochromis niloticus	87.13	0.00e+00	3472.00
IUUC-Ola-086738	Oryzias latipes	86.25	0.00e+00	3414.00
IUUC-Oga-088436	Otolemur garnettii	89.30	0.00e+00	3498.00
IUUC-Oar-090153	Ovis aries	91.25	0.00e+00	3586.00
IUUC-Ptr-091008	Pan troglodytes	90.87	0.00e+00	3546.00
IUUC-Pan-092404	Papio anubis	91.56	0.00e+00	3571.00
IUUC-Psi-093417	Pelodiscus sinensis	95.62	0.00e+00	3679.00
IUUC-Pfo-096073	Poecilia formosa	87.21	0.00e+00	3473.00
IUUC-Pab-097900	Pongo abelii	90.60	0.00e+00	3545.00
IUUC-Pca-100107	Procavia capensis	76.01	0.00e+00	2413.00
IUUC-Pva-102880	Pteropus vampyrus	87.74	0.00e+00	3376.00
IUUC-Rno-106084	Rattus norvegicus	90.13	0.00e+00	3568.00
IUUC-Sha-106974	Sarcophilus harrisii	92.71	0.00e+00	3631.00
IUUC-Sar-113401	Sorex araneus	80.24	0.00e+00	1751.00
IUUC-Ssc-116057	Sus scrofa	90.37	0.00e+00	3606.00
IUUC-Tru-118444	Takifugu rubripes	86.31	0.00e+00	3392.00
IUUC-Tsy-118941	Tarsius syrichta	80.44	0.00e+00	2728.00
IUUC-Tni-120683	Tetraodon nigroviridis	85.85	0.00e+00	3367.00
IUUC-Tbe-127467	Tupaia belangeri	83.73	0.00e+00	1771.00
IUUC-Ttr-129138	Tursiops truncatus	87.26	0.00e+00	3392.00
IUUC-Vpa-130083	Vicugna pacos	85.74	0.00e+00	3304.00
IUUC-Xtr-131835	Xenopus tropicalis	90.20	0.00e+00	3581.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence