iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
RAID2
Protein-protein Interaction
IID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	86.03	0.00e+00	962.00	IUUC-Hsa-046580

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MSENRKPLPG FVNKLQDASA SGSSGKTHCP SCLRLFKVPR LLPCLHTVCT SCLERLDPFS 60
VVDIRGGDSD TSSEGSIFQE PKSCSLKPQI GILCPVCDAQ VDLPLGGVKA LTVDHLAMND 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTGCACTCT CACACTCTGG GAGAGCCTAA GGACACCTCA TCGCCTGGAG GGGAGGGTGC 60
GCTTGTGGCG TGGTGGGGGC GGGACCAGTG GGGCGGGAGG GAGGGTGGCC TTGGAGGAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003649--Bbox_C
IPR017868--Filamin/ABP280_repeat-like
IPR001298--Filamin/ABP280_rpt
IPR013783--Ig-like_fold
IPR014756--Ig_E-set
IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50194--FILAMIN_REPEAT
PS50119--ZF_BBOX
PS00518--ZF_RING_1

Pfam

PF00630--Filamin
PF00643--zf-B_box
PF13445--zf-RING_UBOX

SMART

SM00502--BBC
SM00336--BBOX
SM00557--IG_FLMN
SM00184--RING

Gene Ontology

GO:0005829--C:cytosol
GO:0045171--C:intercellular bridge
GO:0005654--C:nucleoplasm
GO:0008270--F:zinc ion binding
GO:0060348--P:bone development

KEGG

rno:295323

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002020	Ailuropoda melanoleuca	87.07	0.00e+00	970.00
IUUC-Ame-010865	Astyanax mexicanus	46.43	2.00e-122	432.00
IUUC-Bta-012744	Bos taurus	84.66	0.00e+00	951.00
IUUC-Cel-018225	Caenorhabditis elegans	24.74	4.00e-20	93.60
IUUC-Cja-019162	Callithrix jacchus	83.97	0.00e+00	937.00
IUUC-Cfa-020163	Canis familiaris	87.07	0.00e+00	969.00
IUUC-Csa-023746	Chlorocebus sabaeus	86.21	0.00e+00	963.00
IUUC-Cho-024414	Choloepus hoffmanni	73.98	0.00e+00	712.00
IUUC-Dre-028598	Danio rerio	48.83	3.00e-116	412.00
IUUC-Dno-029616	Dasypus novemcinctus	84.85	0.00e+00	947.00
IUUC-Dor-030216	Dipodomys ordii	79.64	5.00e-65	241.00
IUUC-Dme-031817	Drosophila melanogaster	30.43	8.00e-63	235.00
IUUC-Ete-032434	Echinops telfairi	83.27	0.00e+00	868.00
IUUC-Eca-034410	Equus caballus	85.34	0.00e+00	963.00
IUUC-Eeu-034954	Erinaceus europaeus	83.65	0.00e+00	942.00
IUUC-Fca-035410	Felis catus	85.86	0.00e+00	954.00
IUUC-Gmo-039232	Gadus morhua	47.16	3.00e-125	442.00
IUUC-Gac-042350	Gasterosteus aculeatus	45.18	1.00e-102	367.00
IUUC-Ggo-045080	Gorilla gorilla	86.55	0.00e+00	964.00
IUUC-Hsa-046580	Homo sapiens	86.03	0.00e+00	957.00
IUUC-Itr-048145	Ictidomys tridecemlineatus	84.14	0.00e+00	933.00
IUUC-Lch-049464	Latimeria chalumnae	57.60	0.00e+00	631.00
IUUC-Lpe-050809	Leersia perrieri	39.74	8.00e-07	49.30
IUUC-Loc-052772	Lepisosteus oculatus	52.48	3.00e-68	253.00
IUUC-Mcc-055349	Macaca mulatta	84.48	0.00e+00	934.00
IUUC-Meu-056674	Macropus eugenii	64.20	0.00e+00	722.00
IUUC-Mmr-061225	Microcebus murinus	85.84	0.00e+00	949.00
IUUC-Mdo-062597	Monodelphis domestica	61.47	0.00e+00	664.00
IUUC-Mmu-063099	Mus musculus	92.93	0.00e+00	1040.00
IUUC-Mlu-067034	Myotis lucifugus	84.14	0.00e+00	939.00
IUUC-Nle-069855	Nomascus leucogenys	86.55	0.00e+00	994.00
IUUC-Opr-070954	Ochotona princeps	85.31	0.00e+00	941.00
IUUC-Ont-071292	Oreochromis niloticus	48.59	1.00e-126	446.00
IUUC-Ogl-077726	Oryza glaberrima	39.74	6.00e-07	50.10
IUUC-Ogu-078410	Oryza glumaepatula	39.74	5.00e-07	50.10
IUUC-Oni-083081	Oryza nivara	39.74	6.00e-07	50.10
IUUC-Oru-084365	Oryza rufipogon	39.74	3.00e-07	51.20
IUUC-Osa-085953	Oryza sativa	39.74	6.00e-07	50.10
IUUC-Oga-087909	Otolemur garnettii	83.28	0.00e+00	936.00
IUUC-Oar-089619	Ovis aries	84.66	0.00e+00	949.00
IUUC-Ptr-090712	Pan troglodytes	85.69	0.00e+00	953.00
IUUC-Pan-092806	Papio anubis	86.03	0.00e+00	962.00
IUUC-Psi-093414	Pelodiscus sinensis	63.20	0.00e+00	692.00
IUUC-Pfo-096848	Poecilia formosa	47.50	1.00e-126	446.00
IUUC-Pab-098353	Pongo abelii	84.66	0.00e+00	958.00
IUUC-Pca-100183	Procavia capensis	83.62	0.00e+00	944.00
IUUC-Pva-102140	Pteropus vampyrus	83.10	0.00e+00	941.00
IUUC-Sha-107458	Sarcophilus harrisii	63.83	0.00e+00	679.00
IUUC-Sly-111723	Solanum lycopersicum	33.72	2.00e-05	44.70
IUUC-Sar-112944	Sorex araneus	65.00	0.00e+00	653.00
IUUC-Sbi-114481	Sorghum bicolor	38.96	1.00e-06	48.90
IUUC-Ssc-116231	Sus scrofa	85.17	0.00e+00	951.00
IUUC-Tgu-116859	Taeniopygia guttata	54.79	2.00e-150	525.00
IUUC-Tru-118209	Takifugu rubripes	47.86	3.00e-127	448.00
IUUC-Tni-120290	Tetraodon nigroviridis	48.57	3.00e-114	405.00
IUUC-Tvi-122468	Trichoderma virens	31.00	3.00e-03	38.10
IUUC-Tbe-128111	Tupaia belangeri	86.91	0.00e+00	844.00
IUUC-Ttr-128584	Tursiops truncatus	82.24	0.00e+00	883.00
IUUC-Vvi-131620	Vitis vinifera	33.00	3.00e-06	44.70
IUUC-Xtr-132137	Xenopus tropicalis	43.65	2.00e-105	376.00
IUUC-Xma-134298	Xiphophorus maculatus	46.97	2.00e-128	452.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence