iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Itr-048292

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01094586

Gene Name

WDR77

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000025877.1	ENSSTOT00000025212.1	ENSSTOP00000019062.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.70e-18	64.9	166	202

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf...sdtllvsGsdDgtikvWDlrtgvl 35
           H++ vtc+a     d +++s+s D+ i +WD+r+ ++
   Q: 166  HAGQVTCVAAsphKDSMFLSCSEDNRILLWDTRSPKP 202
           99******988765599**************998765 PP

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MRKETPPPLV APAAREWNLP PNAPACMERQ LEAARYRSDG ALLLGASSLS GRCWAGSLWL 60
FKDPCAAPNE GFCSAGVQTE AGVADLTWVG ERGILVASDS GAVELWELDE NETLIVSKFC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCTTCCAGA GGGGCGGAGG CCCGGAGGTG CACCACGTGT GGGTTACTGC TCGAGCTGAA 60
TCGCGGAGAC TTAACAGTTT GGGTTTAGGT TGGATTTGGA ACCGTGGAGA TGCGAAAGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005794--C:Golgi apparatus
GO:0034709--C:methylosome
GO:0005654--C:nucleoplasm
GO:0030374--F:ligand-dependent nuclear receptor transcription coactivator activity
GO:0008327--F:methyl-CpG binding
GO:0060770--P:negative regulation of epithelial cell proliferation involved in prostate gland development
GO:0008284--P:positive regulation of cell proliferation
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0060528--P:secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002192	Ailuropoda melanoleuca	91.84	3.00e-175	607.00
IUUC-Apl-003921	Anas platyrhynchos	62.63	2.00e-66	244.00
IUUC-Aca-004870	Anolis carolinensis	71.33	1.00e-117	415.00
IUUC-Ame-011872	Astyanax mexicanus	47.22	3.00e-39	154.00
IUUC-Bta-013325	Bos taurus	92.40	3.00e-177	613.00
IUUC-Cja-019059	Callithrix jacchus	94.74	6.00e-180	622.00
IUUC-Cfa-021036	Canis familiaris	91.75	1.00e-153	535.00
IUUC-Cpo-022369	Cavia porcellus	92.40	2.00e-176	610.00
IUUC-Csa-023585	Chlorocebus sabaeus	95.32	0.00e+00	630.00
IUUC-Cho-024470	Choloepus hoffmanni	84.65	4.00e-113	399.00
IUUC-Dno-029867	Dasypus novemcinctus	89.18	7.00e-174	602.00
IUUC-Dor-030834	Dipodomys ordii	67.35	8.00e-118	416.00
IUUC-Ete-032245	Echinops telfairi	83.85	1.00e-137	482.00
IUUC-Eca-033360	Equus caballus	92.40	4.00e-175	606.00
IUUC-Eeu-035353	Erinaceus europaeus	89.47	2.00e-172	597.00
IUUC-Fca-036277	Felis catus	92.98	1.00e-177	615.00
IUUC-Fal-037383	Ficedula albicollis	66.80	2.00e-98	351.00
IUUC-Gmo-038575	Gadus morhua	55.56	7.00e-100	356.00
IUUC-Gga-040658	Gallus gallus	69.63	1.00e-126	446.00
IUUC-Gac-041463	Gasterosteus aculeatus	51.41	5.00e-83	300.00
IUUC-Ggo-045120	Gorilla gorilla	93.86	7.00e-180	622.00
IUUC-Hsa-046247	Homo sapiens	94.15	2.00e-180	624.00
IUUC-Lch-049741	Latimeria chalumnae	66.03	8.00e-111	392.00
IUUC-Loc-052695	Lepisosteus oculatus	58.77	1.00e-104	372.00
IUUC-Laf-054535	Loxodonta africana	89.94	8.00e-173	598.00
IUUC-Mcc-054699	Macaca mulatta	95.32	0.00e+00	630.00
IUUC-Meu-056053	Macropus eugenii	77.98	2.00e-134	471.00
IUUC-Mga-059672	Meleagris gallopavo	64.43	1.00e-71	261.00
IUUC-Mmr-060963	Microcebus murinus	94.44	0.00e+00	627.00
IUUC-Mdo-062694	Monodelphis domestica	75.00	3.00e-132	464.00
IUUC-Mmu-064031	Mus musculus	90.35	2.00e-173	600.00
IUUC-Mpu-066408	Mustela putorius furo	92.98	2.00e-178	617.00
IUUC-Mlu-068184	Myotis lucifugus	89.50	4.00e-171	593.00
IUUC-Nle-069251	Nomascus leucogenys	95.03	0.00e+00	628.00
IUUC-Opr-071156	Ochotona princeps	84.80	3.00e-160	557.00
IUUC-Ont-072683	Oreochromis niloticus	57.10	9.00e-97	346.00
IUUC-Oan-073042	Ornithorhynchus anatinus	75.35	9.00e-124	436.00
IUUC-Ocu-074843	Oryctolagus cuniculus	93.88	2.00e-174	604.00
IUUC-Ola-086929	Oryzias latipes	52.50	3.00e-87	314.00
IUUC-Oga-088237	Otolemur garnettii	92.69	3.00e-177	613.00
IUUC-Oar-089312	Ovis aries	92.41	3.00e-162	563.00
IUUC-Ptr-091625	Pan troglodytes	94.15	4.00e-180	623.00
IUUC-Pan-091902	Papio anubis	90.99	5.00e-172	596.00
IUUC-Psi-094035	Pelodiscus sinensis	70.85	3.00e-123	434.00
IUUC-Pma-094565	Petromyzon marinus	61.24	2.00e-54	204.00
IUUC-Pfo-097070	Poecilia formosa	54.17	2.00e-90	325.00
IUUC-Pab-098007	Pongo abelii	94.74	0.00e+00	626.00
IUUC-Pca-100513	Procavia capensis	73.31	1.00e-102	365.00
IUUC-Pva-102821	Pteropus vampyrus	86.84	4.00e-161	560.00
IUUC-Rno-105836	Rattus norvegicus	89.94	4.00e-175	606.00
IUUC-Sha-106847	Sarcophilus harrisii	71.60	8.00e-86	309.00
IUUC-Sar-113451	Sorex araneus	84.55	2.00e-163	567.00
IUUC-Ssc-115978	Sus scrofa	92.40	3.00e-175	607.00
IUUC-Tgu-116745	Taeniopygia guttata	69.30	5.00e-92	330.00
IUUC-Tru-117945	Takifugu rubripes	52.17	2.00e-78	285.00
IUUC-Tsy-119059	Tarsius syrichta	90.40	9.00e-92	328.00
IUUC-Tni-120414	Tetraodon nigroviridis	54.23	1.00e-91	329.00
IUUC-Tbe-127559	Tupaia belangeri	95.91	0.00e+00	634.00
IUUC-Ttr-128505	Tursiops truncatus	90.06	1.00e-170	591.00
IUUC-Vpa-130350	Vicugna pacos	93.96	7.00e-97	345.00
IUUC-Xtr-132939	Xenopus tropicalis	62.46	2.00e-111	395.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence