iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMUSG00000021147.16	ENSMUST00000021572.10	ENSMUSP00000021572.4
ENSMUSG00000021147.16	ENSMUST00000177537.7	ENSMUSP00000135577.1
ENSMUSG00000021147.16	ENSMUST00000176098.7	ENSMUSP00000135094.1
ENSMUSG00000021147.16	ENSMUST00000176429.7	ENSMUSP00000134916.1
ENSMUSG00000021147.16	ENSMUST00000176329.7	ENSMUSP00000135101.1
ENSMUSG00000021147.16	ENSMUST00000176715.1	ENSMUSP00000134987.1
ENSMUSG00000021147.16	ENSMUST00000176922.7	ENSMUSP00000135742.1
ENSMUSG00000021147.16	ENSMUST00000176587.1	ENSMUSP00000135271.1

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
AREsite	miRTarBase	microRNA	TRANSFAC
RepTar	RAID2
Protein-protein Interaction
IID	iRefIndex	HINT	Mentha
Post-translational Modifications (PTMs)
CPLM	dbPAF	PhosphositePlus	dbPTM
PHOSIDA	mUbiSiDa
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.10e-23	83.4	367	398
UBD/Beta-Prp	3.00e-45	155.8	280	488

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sdtllvsGsdDgtikvWDlr 31
           gHtd vt+  f  ++ +vsGsdD t+kvWDl+
   Q: 367  GHTDTVTSAVFtVGDNVVSGSDDRTVKVWDLK 398
           8*******99*733669*************96 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkc..vhtlkgh 93
           ++h++v+ + ++  ++++++t+s+d+t  ++dv+t  l++sl gh++e t ++ +p++ + vt+s+D t ++wd++++++  v +++gh
   Q: 280  KSHQGVVIAADWLVGGKQVVTASWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIhsVNVFQGH 368
           456667777999999*************************************************************665422889**** PP
   S: 94   edsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl...ktgkllrtltggh 179
           +d+v+s  f   gd +vsGs+drt++vwdl++     +t +  + ++n ++v   +++++  +++r+vrl+d+   + ++l r  ++gh
   Q: 369  TDTVTSAVFTV-GDNVVSGSDDRTVKVWDLKNMRSPIATIRTDS-AINRINVCVGQKIIALPHDNRQVRLFDMsgvRLARLPRSSRQGH 455
           ******99999.********************988874555555.55555555559*****************555555555555777* PP
   S: 180  tdsvyslsfdsng..kelvsgsldgtvklwdlq 210
            ++v + +++++     l +++ d++ + w++ 
   Q: 456  RRMVCCSAWSEDHpiCNLFTCGFDRQAIGWNIN 488
           ************9777899***********986 PP

Organism

Mus musculus

Protein Sequence
(Fasta)

MPTESGSCST ARQAKQKRKS HSLSIRRTNS SEQERTGLPR EMLEGQDSKL PSSVRSTLLE 60
LFGQIEREFE NLYIENLELR REIDTLNERL AGEGQAIDGA ELSKGQLKTK ASHSTSQLSQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTCTGCTAT GTAGGTCTTC CCAACCCTGA TTAACGGGGA AAAGCGGCTC AAGTCCCACC 60
TTTTGCAGTG AACAGCTGAT TCTATTTTCC CCTCTTAGCC AATGGTGATC AGATATTTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0070545--C:PeBoW complex
GO:0030687--C:preribosome, large subunit precursor
GO:0000460--P:maturation of 5.8S rRNA
GO:0000470--P:maturation of LSU-rRNA

KEGG

mmu:207615

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001249	Ailuropoda melanoleuca	95.36	0.00e+00	961.00
IUUC-Apl-003647	Anas platyrhynchos	93.75	0.00e+00	938.00
IUUC-Aca-004759	Anolis carolinensis	93.55	0.00e+00	951.00
IUUC-Ame-011103	Astyanax mexicanus	56.63	6.00e-145	507.00
IUUC-Bta-012718	Bos taurus	94.35	0.00e+00	952.00
IUUC-Cel-018499	Caenorhabditis elegans	42.27	1.00e-96	346.00
IUUC-Cja-019492	Callithrix jacchus	96.77	0.00e+00	996.00
IUUC-Cfa-020199	Canis familiaris	94.96	0.00e+00	991.00
IUUC-Cpo-022500	Cavia porcellus	91.73	0.00e+00	949.00
IUUC-Csa-023567	Chlorocebus sabaeus	97.38	0.00e+00	1002.00
IUUC-Cho-025071	Choloepus hoffmanni	69.15	0.00e+00	650.00
IUUC-Cin-025460	Ciona intestinalis	45.18	9.00e-105	374.00
IUUC-Csv-026042	Ciona savignyi	46.43	5.00e-109	387.00
IUUC-Dre-028214	Danio rerio	83.06	0.00e+00	869.00
IUUC-Dno-029826	Dasypus novemcinctus	96.14	0.00e+00	830.00
IUUC-Dor-030967	Dipodomys ordii	96.91	0.00e+00	899.00
IUUC-Dme-031936	Drosophila melanogaster	49.58	4.00e-119	421.00
IUUC-Ete-032452	Echinops telfairi	92.94	0.00e+00	952.00
IUUC-Eca-033278	Equus caballus	95.97	0.00e+00	996.00
IUUC-Eeu-034592	Erinaceus europaeus	83.67	0.00e+00	832.00
IUUC-Fca-036431	Felis catus	95.98	0.00e+00	995.00
IUUC-Fal-037149	Ficedula albicollis	93.15	0.00e+00	936.00
IUUC-Gmo-038476	Gadus morhua	80.08	0.00e+00	778.00
IUUC-Gga-041099	Gallus gallus	93.75	0.00e+00	939.00
IUUC-Gac-042374	Gasterosteus aculeatus	84.40	0.00e+00	825.00
IUUC-Ggo-044683	Gorilla gorilla	89.11	0.00e+00	906.00
IUUC-Hsa-046658	Homo sapiens	96.57	0.00e+00	995.00
IUUC-Itr-048870	Ictidomys tridecemlineatus	98.24	0.00e+00	932.00
IUUC-Lch-050571	Latimeria chalumnae	85.01	0.00e+00	884.00
IUUC-Loc-052652	Lepisosteus oculatus	82.06	0.00e+00	867.00
IUUC-Laf-053712	Loxodonta africana	94.99	0.00e+00	981.00
IUUC-Mcc-055521	Macaca mulatta	97.38	0.00e+00	1002.00
IUUC-Meu-056324	Macropus eugenii	90.32	0.00e+00	895.00
IUUC-Mga-060114	Meleagris gallopavo	93.95	0.00e+00	946.00
IUUC-Mmr-061176	Microcebus murinus	95.97	0.00e+00	990.00
IUUC-Mdo-061888	Monodelphis domestica	95.16	0.00e+00	934.00
IUUC-Mpu-066220	Mustela putorius furo	82.89	0.00e+00	631.00
IUUC-Mlu-068155	Myotis lucifugus	96.57	0.00e+00	1000.00
IUUC-Nle-069964	Nomascus leucogenys	96.77	0.00e+00	998.00
IUUC-Opr-070925	Ochotona princeps	95.29	1.00e-151	529.00
IUUC-Ont-071317	Oreochromis niloticus	86.09	0.00e+00	849.00
IUUC-Oan-072952	Ornithorhynchus anatinus	95.16	0.00e+00	959.00
IUUC-Ocu-073913	Oryctolagus cuniculus	97.98	0.00e+00	1011.00
IUUC-Ola-087024	Oryzias latipes	84.71	0.00e+00	885.00
IUUC-Oga-087945	Otolemur garnettii	96.57	0.00e+00	1004.00
IUUC-Oar-089854	Ovis aries	94.76	0.00e+00	944.00
IUUC-Ptr-091486	Pan troglodytes	96.77	0.00e+00	997.00
IUUC-Pan-091738	Papio anubis	97.38	0.00e+00	1002.00
IUUC-Psi-093953	Pelodiscus sinensis	93.75	0.00e+00	942.00
IUUC-Pma-094560	Petromyzon marinus	76.13	0.00e+00	776.00
IUUC-Pfo-097222	Poecilia formosa	83.47	0.00e+00	837.00
IUUC-Pab-098778	Pongo abelii	91.73	0.00e+00	934.00
IUUC-Pca-100852	Procavia capensis	91.73	0.00e+00	930.00
IUUC-Pva-103130	Pteropus vampyrus	94.63	4.00e-134	471.00
IUUC-Rno-105848	Rattus norvegicus	89.92	0.00e+00	898.00
IUUC-Sha-106750	Sarcophilus harrisii	95.36	0.00e+00	965.00
IUUC-Sar-113749	Sorex araneus	87.10	0.00e+00	882.00
IUUC-Ssc-115691	Sus scrofa	92.94	0.00e+00	931.00
IUUC-Tgu-117365	Taeniopygia guttata	92.54	0.00e+00	891.00
IUUC-Tru-117595	Takifugu rubripes	84.48	0.00e+00	838.00
IUUC-Tsy-118973	Tarsius syrichta	75.55	1.00e-153	536.00
IUUC-Tni-120545	Tetraodon nigroviridis	83.73	0.00e+00	868.00
IUUC-Tbe-127976	Tupaia belangeri	72.78	0.00e+00	700.00
IUUC-Ttr-128472	Tursiops truncatus	92.34	0.00e+00	944.00
IUUC-Xtr-132621	Xenopus tropicalis	91.94	0.00e+00	907.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence