iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-050151

Ensembl Protein ID

ENSLACP00000017807.1

UniProt Accession

H3B7D6; H3B7D6_LATCH

Genbank Protein ID

ENSLACP00000017807

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01038193

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000015685.1	ENSLACT00000017937.1	ENSLACP00000017807.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.80e-37	125.3	416	450
UBD/Beta-Prp	2.90e-57	194.3	184	481

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 4    dsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           +++tc+af s+ ++l++G+++gtikvW+l  g+ l
   Q: 416  EEITCMAFdSSlRRLITGARNGTIKVWNLQNGHNL 450
           67******98899***************9988766 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrd..gtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvw.dlstgkcvht 89
           ++ + +k+ it++ + p++++l+t+s++  +++ + d++++k++ + +  + +vt+ +f+++ ++lvtg+ D+t+++w  + t+ ++  
   Q: 184  VVPEVQKEAITKIMYEPEGDFLITSSANpmRSVVIMDIHRKKKVYTWKIRK-GVTCFDFNKSLNLLVTGGVDHTVRLWnQYVTSRPTAL 271
           556778999*****************98556899******99988887666.9*************************8899******* PP
   S: 90   lkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee............................................... 131
           l+gh  +vl++++++    + s s+d++++vwd+ ++ cl++                                               
   Q: 272  LHGHCLTVLDVAINEPLGQIFSYSKDSVLKVWDILSYNCLRTlvlkfpciqpgrilehgefpfllvqqhphvllvscadyiamlkleha 360
           ***************************************************************************************** PP
   S: 132  .....tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltggh.tdsvyslsfdsngkelvsgsldgtvklwdlqtgec 214
                +l  h++  +++ ++p+   +v+G++D+ v +Wd++tg+   +lt  h t+ +++++fds+ ++l++g+++gt+k+w+lq+g+ 
   Q: 361  dhegeILLTHSAQLCSAIYNPFFHQVVTGCDDSSVAVWDVETGTKCLQLTNVHgTEEITCMAFDSSLRRLITGARNGTIKVWNLQNGHN 449
           *******************************************98888866553789******************************** PP
   S: 215  vrtlng.htdnvksvrfspnderlvsgssDgs 245
           +++l+   ++ v+ v  ++++++lv+g s++ 
   Q: 450  LHRLEVvMEAEVTGVLPFQDQKFLVVGWSHKI 481
           ****9856789**************9987764 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

ILCFFTAAAA HQEATARILA VPSPPPLRFM SVSRGGVLTV WDNDLRMQKS YKISTEANDL 60
HAGKRRFKSW TTDAVYMPNV HKVAIATTSR DIHFFDVSTA SCFEELHLYA LNNVPNCLCY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATACTTTGTT TCTTTACTGC TTTAAAGAGA CATTTTTATC TTTTTTTTTG ACAGTGTCCA 60
AATTCCTTTT TCTTTTCATT TTTTTTTTTT TAAACTTTAA TCCCCTTCTT AAAGACGCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR020472--G-protein_beta_WD-40_rep
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cin-025187	Ciona intestinalis	43.81	3.00e-173	601.00
IUUC-Dre-027920	Danio rerio	48.64	0.00e+00	632.00
IUUC-Gmo-039225	Gadus morhua	45.57	2.00e-118	418.00
IUUC-Loc-052558	Lepisosteus oculatus	64.34	0.00e+00	921.00
IUUC-Mdo-062601	Monodelphis domestica	54.34	0.00e+00	736.00
IUUC-Ont-072106	Oreochromis niloticus	45.88	0.00e+00	635.00
IUUC-Ppa-095538	Physcomitrella patens	35.54	1.00e-20	94.70
IUUC-Tru-117878	Takifugu rubripes	44.88	4.00e-115	407.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence