iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-045605

UUCD1 version

UUC-GoG-00433

Ensembl Protein ID

ENSGGOP00000010435.2

UniProt Accession

G3R566; G3R566_GORGO

Protein Name

Uncharacterized protein

Gene Name

GEMIN5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000010687.2	ENSGGOT00000010742.2	ENSGGOP00000010435.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.10e-32	109.6	511	542
UBD/Beta-Prp	1.30e-48	166.1	57	314

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtllvsGsdDgtikvWD 29
           gHt+++t++a+   +d++lvs+s+Dgt +vWD
   Q: 511  GHTAKITSVAWsphHDGRLVSASYDGTAQVWD 542
           8***********8766**************** PP

UBD/Beta-Prp

   S: 45   lrslsgheaevtavkfspdgk...ilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp.sgdklvsGshdrtirvwdletgqcl 129
           + +l gh++ v+  +fs++     + +t+s+D+t+k+wd++t + v     h++++ +l++sp  +d +vsG++  ++ ++  + +   
   Q: 57   IGELVGHTERVSGFTFSHHPGqynLCATSSDDGTVKIWDVETKTVVTEHALHQHTISTLHWSPrVKDLIVSGDEKGVVFCYWFNRNDSQ 145
           7899**************965677***************************************666**************644444433 PP
   S: 130  ee.....................tlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdl.............ktgkllrtl........ 175
           +                      ++++ +  + +++ + ++ ++l++Gs+D+t+r+W+              +       +        
   Q: 146  HLfieprtifcltcsphhedlvaIEAEITNGNAVAQAPVTKgCYLATGSKDQTIRIWSCsrgrgellqwdltQ------SWrrkytlfs 228
           33799***************9998888888888888888888****************989888776665442......2222224454 PP
   S: 176  ...tgghtdsvysls........fdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfs.pnderlvsgssDgsiriWdlr 252
              +g    + +s +         +++++ l+s s+d++vk wd+ t ec  tl     + +s++fs  +   l+ g  Dg ir+W++ 
   Q: 229  assEG----QNHSRIvfnlcplqTEDDKQLLLSTSMDRDVKCWDVATLECCWTLPSLGGFAYSLAFSsVDIGSLAIGVGDGMIRVWNTL 313
           44422....2222223334576677777***************************************533344455557*******754 PP
   S: 253  s 253
           s
   Q: 314  S 314
           4 PP

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MGQEPRTLPP SPNWYCARCS DAVPGGLFGF AARTSVFLVR VGPGAGESPG TPPFRVIGEL 60
VGHTERVSGF TFSHHPGQYN LCATSSDDGT VKIWDVETKT VVTEHALHQH TISTLHWSPR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGGCAGG AGCCGCGGAC TCTGCCGCCC TCTCCCAACT GGTACTGCGC CCGCTGCAGC 60
GATGCCGTGC CCGGGGGCCT CTTTGGCTTC GCCGCGCGGA CCTCCGTCTT CCTTGTCCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0022625--C:cytosolic large ribosomal subunit
GO:0016020--C:membrane
GO:0016604--C:nuclear body
GO:0032797--C:SMN complex
GO:0034718--C:SMN-Gemin2 complex
GO:0034719--C:SMN-Sm protein complex
GO:0003730--F:mRNA 3'-UTR binding
GO:0043022--F:ribosome binding
GO:0000340--F:RNA 7-methylguanosine cap binding
GO:0030619--F:U1 snRNA binding
GO:0030621--F:U4 snRNA binding
GO:0030622--F:U4atac snRNA binding
GO:0006417--P:regulation of translation
GO:0000387--P:spliceosomal snRNP assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001199	Ailuropoda melanoleuca	81.05	0.00e+00	1842.00
IUUC-Apl-003586	Anas platyrhynchos	61.86	0.00e+00	1167.00
IUUC-Aca-004956	Anolis carolinensis	57.17	0.00e+00	1277.00
IUUC-Ame-010753	Astyanax mexicanus	48.96	0.00e+00	1103.00
IUUC-Bta-012315	Bos taurus	80.15	0.00e+00	1837.00
IUUC-Cja-019334	Callithrix jacchus	84.32	0.00e+00	2029.00
IUUC-Cfa-021254	Canis familiaris	81.00	0.00e+00	1889.00
IUUC-Cpo-021984	Cavia porcellus	75.25	0.00e+00	1670.00
IUUC-Csa-023650	Chlorocebus sabaeus	85.63	0.00e+00	2009.00
IUUC-Cho-024860	Choloepus hoffmanni	78.83	0.00e+00	1770.00
IUUC-Cin-025778	Ciona intestinalis	32.66	2.00e-147	516.00
IUUC-Csv-026313	Ciona savignyi	33.96	2.00e-113	403.00
IUUC-Dre-028096	Danio rerio	51.60	0.00e+00	750.00
IUUC-Dno-029799	Dasypus novemcinctus	78.30	0.00e+00	1835.00
IUUC-Dor-030885	Dipodomys ordii	64.29	8.00e-137	482.00
IUUC-Ete-032918	Echinops telfairi	73.34	0.00e+00	1714.00
IUUC-Eca-034144	Equus caballus	80.62	0.00e+00	1814.00
IUUC-Eeu-034843	Erinaceus europaeus	81.12	0.00e+00	1392.00
IUUC-Fca-035948	Felis catus	79.93	0.00e+00	1815.00
IUUC-Fal-037303	Ficedula albicollis	54.95	0.00e+00	1202.00
IUUC-Gmo-039591	Gadus morhua	45.69	0.00e+00	637.00
IUUC-Gga-040570	Gallus gallus	59.80	0.00e+00	1149.00
IUUC-Gac-042646	Gasterosteus aculeatus	46.95	0.00e+00	1051.00
IUUC-Hsa-046122	Homo sapiens	87.36	0.00e+00	2034.00
IUUC-Itr-048094	Ictidomys tridecemlineatus	80.49	0.00e+00	1825.00
IUUC-Lch-050489	Latimeria chalumnae	44.80	1.00e-174	607.00
IUUC-Loc-052259	Lepisosteus oculatus	48.37	0.00e+00	1064.00
IUUC-Laf-053338	Loxodonta africana	79.05	0.00e+00	1848.00
IUUC-Mcc-055442	Macaca mulatta	85.71	0.00e+00	2007.00
IUUC-Meu-056245	Macropus eugenii	59.96	9.00e-160	558.00
IUUC-Mga-060202	Meleagris gallopavo	57.50	0.00e+00	1187.00
IUUC-Mmr-061730	Microcebus murinus	82.08	0.00e+00	1880.00
IUUC-Mdo-062880	Monodelphis domestica	69.78	0.00e+00	1579.00
IUUC-Mmu-063930	Mus musculus	76.60	0.00e+00	1639.00
IUUC-Mpu-066605	Mustela putorius furo	80.95	0.00e+00	1895.00
IUUC-Mlu-067765	Myotis lucifugus	79.82	0.00e+00	1838.00
IUUC-Nle-069183	Nomascus leucogenys	85.98	0.00e+00	1974.00
IUUC-Opr-070659	Ochotona princeps	80.86	0.00e+00	800.00
IUUC-Ont-072356	Oreochromis niloticus	50.42	0.00e+00	758.00
IUUC-Oan-073056	Ornithorhynchus anatinus	67.54	0.00e+00	1440.00
IUUC-Ocu-073881	Oryctolagus cuniculus	81.42	0.00e+00	1890.00
IUUC-Ola-087120	Oryzias latipes	54.27	3.00e-46	177.00
IUUC-Olu-087648	Ostreococcus lucimarinus	23.06	6.00e-17	83.20
IUUC-Oga-088343	Otolemur garnettii	82.25	0.00e+00	1899.00
IUUC-Oar-089257	Ovis aries	80.78	0.00e+00	1865.00
IUUC-Ptr-090497	Pan troglodytes	87.12	0.00e+00	1998.00
IUUC-Pan-092638	Papio anubis	85.33	0.00e+00	1991.00
IUUC-Psi-093096	Pelodiscus sinensis	61.49	0.00e+00	1140.00
IUUC-Pma-094571	Petromyzon marinus	44.11	2.00e-87	315.00
IUUC-Pfo-096742	Poecilia formosa	46.81	0.00e+00	1045.00
IUUC-Pab-098153	Pongo abelii	86.47	0.00e+00	2049.00
IUUC-Pca-100957	Procavia capensis	73.95	0.00e+00	1740.00
IUUC-Pva-102439	Pteropus vampyrus	82.08	0.00e+00	1910.00
IUUC-Rno-105891	Rattus norvegicus	76.44	0.00e+00	1649.00
IUUC-Sha-107181	Sarcophilus harrisii	66.92	0.00e+00	1425.00
IUUC-Ssc-115413	Sus scrofa	80.23	0.00e+00	1860.00
IUUC-Tgu-117082	Taeniopygia guttata	59.37	0.00e+00	1331.00
IUUC-Tru-118491	Takifugu rubripes	53.04	4.00e-157	549.00
IUUC-Tsy-119629	Tarsius syrichta	84.52	3.00e-155	543.00
IUUC-Tni-120240	Tetraodon nigroviridis	48.35	0.00e+00	711.00
IUUC-Tbe-127673	Tupaia belangeri	76.13	0.00e+00	1654.00
IUUC-Ttr-128562	Tursiops truncatus	77.00	0.00e+00	1766.00
IUUC-Vpa-130596	Vicugna pacos	74.44	0.00e+00	1558.00
IUUC-Xtr-132469	Xenopus tropicalis	53.47	0.00e+00	1176.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence