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Tag Content
UUCD2 ID IUUC-Nle-069232
UUCD1 version UUC-NoL-00241
Ensembl Protein ID ENSNLEP00000005663.2
UniProt Accession G1QXJ2; G1QXJ2_NOMLE
Genbank Protein ID ENSNLEP00000005663
Protein Name Histone-lysine N-methyltransferase
Genbank Nucleotide ID ADFV01062650
Gene Name KMT2C
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSNLEG00000004634.2 ENSNLET00000005956.2 ENSNLEP00000005663.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/PHD 1.20e-29 102.3 1018 1069
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/PHD
   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsek..wiCpkCr 52
           +C+vC +++++e+ +++C++C++w+H+ C +l+ eee++n  +  + C+ Cr
   Q: 1018 SCPVCYRNYREEDLILQCRQCDRWMHAVCQNLNTEEEVENVADigFDCSMCR 1069
           6********************************999999998899******8 PP
   
Organism Nomascus leucogenys
Protein Sequence
(Fasta)
MDGLETTETE TIVETEIKEQ SAEEDAEAEV DNSKQLIPTL QRSVSEESAN SLVSVGVEAK 60
ISEQLCAFCY CGEKSSLGQG DLKQFRVTPG FILPWRNHPS NKKDIDDNSN GTYEKMQNSA 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Nle-069232|E3,PHD|Nomascus leucogenys
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AGTTTAAGCC TTAAAATTTA ACATTTAACT CTATGTGCTT TTTTTTTTTT TTTTTTTTTT 60
TTTTTCTGTA GACCTCGAAG TAGGGGGAAA ACTGCAGTGG AAGATGAGGA CAGCATGGAT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Nle-069232|E3,PHD|Nomascus leucogenys
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR034732--EPHD
IPR003889--FYrich_C
IPR003888--FYrich_N
IPR009071--HMG_box_dom
IPR003616--Post-SET_dom
IPR001214--SET_dom
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS51805--EPHD
PS51543--FYRC
PS51542--FYRN
PS50868--POST_SET
PS50280--SET
PS50016--ZF_PHD_2
PS50089--ZF_RING_2
Pfam

PF05965--FYRC
PF05964--FYRN
PF00628--PHD
PF00856--SET
SMART

SM00542--FYRC
SM00541--FYRN
SM00398--HMG
SM00249--PHD
SM00508--PostSET
SM00317--SET
Gene Ontology

GO:0044666--C:MLL3/4 complex
GO:0042800--F:histone methyltransferase activity (H3-K4 specific)
GO:0003723--F:RNA binding
GO:0008270--F:zinc ion binding
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002314 Ailuropoda melanoleuca 85.96 0.00e+00 5458.00
IUUC-Apl-003311 Anas platyrhynchos 69.04 0.00e+00 4064.00
IUUC-Aca-004705 Anolis carolinensis 63.02 0.00e+00 3757.00
IUUC-Ame-010612 Astyanax mexicanus 70.55 0.00e+00 882.00
IUUC-Bta-012322 Bos taurus 80.66 0.00e+00 4983.00
IUUC-Cel-018354 Caenorhabditis elegans 35.38 4.00e-64 241.00
IUUC-Cja-019983 Callithrix jacchus 94.51 0.00e+00 6180.00
IUUC-Cfa-020903 Canis familiaris 85.13 0.00e+00 5539.00
IUUC-Cpo-021732 Cavia porcellus 80.18 0.00e+00 5123.00
IUUC-Csa-023083 Chlorocebus sabaeus 97.07 0.00e+00 8359.00
IUUC-Cho-024469 Choloepus hoffmanni 82.02 0.00e+00 2285.00
IUUC-Dre-028110 Danio rerio 56.65 0.00e+00 1447.00
IUUC-Dor-030569 Dipodomys ordii 79.30 0.00e+00 2966.00
IUUC-Dme-031590 Drosophila melanogaster 32.75 2.00e-64 241.00
IUUC-Eca-033945 Equus caballus 87.12 0.00e+00 5185.00
IUUC-Fca-035922 Felis catus 82.83 0.00e+00 5121.00
IUUC-Gmo-038719 Gadus morhua 73.14 0.00e+00 818.00
IUUC-Gac-041896 Gasterosteus aculeatus 43.90 0.00e+00 1791.00
IUUC-Ggo-044812 Gorilla gorilla 93.41 0.00e+00 6128.00
IUUC-Hsa-046595 Homo sapiens 96.79 0.00e+00 6371.00
IUUC-Itr-048303 Ictidomys tridecemlineatus 84.49 0.00e+00 5240.00
IUUC-Lch-050086 Latimeria chalumnae 57.36 0.00e+00 2695.00
IUUC-Loc-052891 Lepisosteus oculatus 55.06 0.00e+00 2416.00
IUUC-Laf-054348 Loxodonta africana 82.78 0.00e+00 3078.00
IUUC-Mcc-054868 Macaca mulatta 96.25 0.00e+00 6273.00
IUUC-Meu-056322 Macropus eugenii 68.03 0.00e+00 1199.00
IUUC-Mga-059541 Meleagris gallopavo 69.03 0.00e+00 4158.00
IUUC-Mmr-061092 Microcebus murinus 90.40 0.00e+00 7765.00
IUUC-Mdo-062610 Monodelphis domestica 74.85 0.00e+00 1997.00
IUUC-Mmu-063666 Mus musculus 82.04 0.00e+00 5135.00
IUUC-Mpu-066366 Mustela putorius furo 82.14 0.00e+00 4894.00
IUUC-Mlu-068201 Myotis lucifugus 81.87 0.00e+00 4141.00
IUUC-Opr-070625 Ochotona princeps 77.16 0.00e+00 1326.00
IUUC-Ont-072401 Oreochromis niloticus 53.25 0.00e+00 1194.00
IUUC-Oan-072945 Ornithorhynchus anatinus 76.54 0.00e+00 6076.00
IUUC-Ocu-074920 Oryctolagus cuniculus 87.02 0.00e+00 7426.00
IUUC-Ola-086436 Oryzias latipes 44.11 0.00e+00 1765.00
IUUC-Oga-088637 Otolemur garnettii 86.04 0.00e+00 4541.00
IUUC-Oar-089363 Ovis aries 79.36 0.00e+00 4885.00
IUUC-Ptr-091527 Pan troglodytes 96.89 0.00e+00 6417.00
IUUC-Pan-092102 Papio anubis 93.29 0.00e+00 5991.00
IUUC-Pma-094252 Petromyzon marinus 44.53 3.00e-160 560.00
IUUC-Pfo-096288 Poecilia formosa 57.30 0.00e+00 1300.00
IUUC-Pab-098241 Pongo abelii 97.59 0.00e+00 3555.00
IUUC-Pca-100103 Procavia capensis 81.58 0.00e+00 1600.00
IUUC-Pva-102238 Pteropus vampyrus 77.12 0.00e+00 2576.00
IUUC-Rno-105395 Rattus norvegicus 75.98 0.00e+00 1120.00
IUUC-Sha-106550 Sarcophilus harrisii 76.10 0.00e+00 6269.00
IUUC-Sar-113183 Sorex araneus 61.98 9.00e-178 619.00
IUUC-Tgu-116677 Taeniopygia guttata 67.60 0.00e+00 3729.00
IUUC-Tru-118037 Takifugu rubripes 60.78 0.00e+00 1175.00
IUUC-Tsy-118932 Tarsius syrichta 88.58 0.00e+00 3623.00
IUUC-Tni-119970 Tetraodon nigroviridis 50.86 0.00e+00 1301.00
IUUC-Ttr-129051 Tursiops truncatus 83.64 0.00e+00 5136.00
IUUC-Vpa-130236 Vicugna pacos 83.17 0.00e+00 1977.00
IUUC-Xtr-132455 Xenopus tropicalis 52.47 0.00e+00 941.00
Created Date 25-Jun-2017

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