iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003693

Ensembl Protein ID

ENSAPLP00000006744.1

UniProt Accession

U3IHM2; U3IHM2_ANAPL

Genbank Protein ID

ENSAPLP00000006744

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Genbank Nucleotide ID

ADON01044951

Gene Name

UCHL1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000007078.1	ENSAPLT00000007393.1	ENSAPLP00000006744.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/Other	69.64	6.00e-90	327.00	IUUC-Hsa-045820
DUB/UCH	69.64	6.00e-90	327.00	IUUC-Hsa-045820
UBD/Other/Other	69.64	6.00e-90	327.00	IUUC-Hsa-045820

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

MQLKPLVVLQ MLNKVLARLG VSPGWRFVDV LGFEEEALGA VPSPAWPEMF EMITCLQHEN 60
FRKQQTEKIK DQEISSKVYF LKQTVSNSCG TIGLIHAVAN NKDKVKLDEG SALKKFLDET 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCAGCTGA AGGTAGGGAC TTGGAATGTC TCAGGGCTTA GCTTCTGGCA GAGGAATAGG 60
AAAATGATCT TCTAAAGCAG TTTATGACCT CAGTTCCCAC ATCAGGGGCT CTGCATTGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0732--Signal
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH
IPR030297--UCHL1

PROSITE

PS00140--UCH_1

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:1904115--C:axon cytoplasm
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0043209--C:myelin sheath
GO:0044306--C:neuron projection terminus
GO:0043025--C:neuronal cell body
GO:0005654--C:nucleoplasm
GO:0005886--C:plasma membrane
GO:0004197--F:cysteine-type endopeptidase activity
GO:0016874--F:ligase activity
GO:0008242--F:omega peptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0007628--P:adult walking behavior
GO:0007412--P:axon target recognition
GO:0019896--P:axonal transport of mitochondrion
GO:0008283--P:cell proliferation
GO:0042755--P:eating behavior
GO:0048747--P:muscle fiber development
GO:0043407--P:negative regulation of MAP kinase activity
GO:0050905--P:neuromuscular process
GO:0016579--P:protein deubiquitination
GO:0002931--P:response to ischemia
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001376	Ailuropoda melanoleuca	62.26	6.00e-85	306.00
IUUC-Aca-004716	Anolis carolinensis	71.75	1.00e-95	341.00
IUUC-Ame-011806	Astyanax mexicanus	56.95	6.00e-71	259.00
IUUC-Bta-013521	Bos taurus	61.66	4.00e-86	310.00
IUUC-Cel-018302	Caenorhabditis elegans	34.76	9.00e-28	116.00
IUUC-Cja-018752	Callithrix jacchus	69.78	5.00e-88	316.00
IUUC-Cfa-020442	Canis familiaris	69.78	1.00e-87	315.00
IUUC-Cpo-021723	Cavia porcellus	70.74	4.00e-74	270.00
IUUC-Csa-023626	Chlorocebus sabaeus	68.75	1.00e-87	315.00
IUUC-Cho-024548	Choloepus hoffmanni	61.32	6.00e-30	123.00
IUUC-Dre-027854	Danio rerio	58.04	1.00e-71	261.00
IUUC-Dno-029325	Dasypus novemcinctus	70.09	4.00e-89	320.00
IUUC-Dor-030114	Dipodomys ordii	68.30	3.00e-89	320.00
IUUC-Ete-033092	Echinops telfairi	72.29	3.00e-71	260.00
IUUC-Eca-033854	Equus caballus	76.22	7.00e-64	235.00
IUUC-Eeu-034493	Erinaceus europaeus	66.07	2.00e-83	301.00
IUUC-Fal-036693	Ficedula albicollis	89.52	2.00e-109	387.00
IUUC-Gmo-038848	Gadus morhua	53.77	1.00e-62	232.00
IUUC-Gga-041078	Gallus gallus	89.24	1.00e-114	404.00
IUUC-Gac-042064	Gasterosteus aculeatus	56.95	9.00e-71	259.00
IUUC-Ggo-044827	Gorilla gorilla	69.64	7.00e-89	319.00
IUUC-Hsa-045820	Homo sapiens	69.64	7.00e-89	319.00
IUUC-Itr-048496	Ictidomys tridecemlineatus	69.20	4.00e-88	317.00
IUUC-Lch-050121	Latimeria chalumnae	60.63	3.00e-80	290.00
IUUC-Loc-052342	Lepisosteus oculatus	60.18	1.00e-77	281.00
IUUC-Laf-053916	Loxodonta africana	68.58	1.00e-86	311.00
IUUC-Mcc-054838	Macaca mulatta	68.75	1.00e-87	315.00
IUUC-Meu-056478	Macropus eugenii	69.64	1.00e-90	325.00
IUUC-Mga-059878	Meleagris gallopavo	91.08	3.00e-112	397.00
IUUC-Mdo-062544	Monodelphis domestica	68.75	1.00e-86	311.00
IUUC-Mmu-063300	Mus musculus	70.09	2.00e-91	327.00
IUUC-Mpu-066128	Mustela putorius furo	68.16	3.00e-75	274.00
IUUC-Mlu-067778	Myotis lucifugus	68.75	3.00e-90	323.00
IUUC-Nle-069686	Nomascus leucogenys	69.64	9.00e-89	318.00
IUUC-Opr-070535	Ochotona princeps	59.82	4.00e-73	266.00
IUUC-Ont-071510	Oreochromis niloticus	55.16	3.00e-70	257.00
IUUC-Ocu-074590	Oryctolagus cuniculus	67.86	4.00e-87	313.00
IUUC-Ola-087552	Oryzias latipes	54.19	2.00e-66	244.00
IUUC-Oga-089013	Otolemur garnettii	61.18	1.00e-84	305.00
IUUC-Oar-089861	Ovis aries	61.66	4.00e-86	310.00
IUUC-Ptr-091536	Pan troglodytes	67.86	2.00e-86	310.00
IUUC-Pan-092909	Papio anubis	68.75	1.00e-87	315.00
IUUC-Psi-093818	Pelodiscus sinensis	75.45	2.00e-98	351.00
IUUC-Pfo-097335	Poecilia formosa	57.14	2.00e-71	261.00
IUUC-Pab-098048	Pongo abelii	69.64	7.00e-89	319.00
IUUC-Pca-100818	Procavia capensis	54.08	4.00e-49	186.00
IUUC-Pva-102954	Pteropus vampyrus	70.09	7.00e-87	312.00
IUUC-Rno-105966	Rattus norvegicus	70.09	2.00e-91	327.00
IUUC-Sha-107111	Sarcophilus harrisii	74.10	5.00e-73	265.00
IUUC-Sar-113190	Sorex araneus	57.39	4.00e-27	112.00
IUUC-Ssc-115908	Sus scrofa	58.41	2.00e-69	254.00
IUUC-Tgu-117465	Taeniopygia guttata	84.83	2.00e-102	364.00
IUUC-Tru-118565	Takifugu rubripes	58.33	8.00e-67	246.00
IUUC-Tsy-119561	Tarsius syrichta	72.29	7.00e-71	259.00
IUUC-Tbe-128048	Tupaia belangeri	74.10	3.00e-73	266.00
IUUC-Ttr-128494	Tursiops truncatus	67.26	5.00e-84	303.00
IUUC-Xtr-132286	Xenopus tropicalis	60.99	1.00e-77	282.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence