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Tag Content
iUUCD ID IUUC-Cne-027054
Ensembl Protein ID AAW45320
UniProt Accession P0CS50; Q55MW6; Q5KB95; SEC13_CRYNJ
Genbank Protein ID AAW45320.1
Protein Name Protein transport protein SEC13
Genbank Nucleotide ID AE017349
Gene Name SEC13; CNI03320
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
CNI03320 AAW45320 AAW45320
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 2.60e-28 95.3 66 98
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sd..tllvsGsdDgtikvWD 29
    gHt+ v+ +++ ++ +l+s+s+Dg + +W
   Q: 66 GHTAAVWQVSWahPSfgSILASCSYDGRVFIWK 98
    8************6665789************6 PP
   

Organism Cryptococcus neoformans
Functional Description
(View)

Functional Description



     Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. It also functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. SEC13 is required for efficient mRNA export from the nucleus to the cytoplasm and for correct nuclear pore biogenesis and distribution (By similarity).
Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. It also functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. SEC13 is required for efficient mRNA export from the nucleus to the cytoplasm and for correct nuclear pore biogenesis and distribution (By similarity).
Protein Sequence
(Fasta)
MCLWPLIQSA QASKPVPVET QHEDMIHDAQ LDYYGKRLAT CSSDRTIRIF NVIKGEAKGE 60
PVILKGHTAA VWQVSWAHPS FGSILASCSY DGRVFIWKEV GQGQGKGSGG ELQDGWERIK 120
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Protein Fasta Sequence



>IUUC-Cne-027054|E3,WD_repeat|Cryptococcus neoformans
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Nucleotide Sequence
(Fasta)
ATGTGCTTAT GGCCCCTCAT ACAGTCCGCT CAAGCATCAA AACCCGTTCC TGTGGAGACT 60
CAGCATGAGG ACATGATCGT TAGTCTAGCC TGTGCCATGC CTTATATCCT GTTTCTGACC 120
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Nucleotide Fasta Sequence



>IUUC-Cne-027054|E3,WD_repeat|Cryptococcus neoformans
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0968--Cytoplasmic vesicle
KW-0256--Endoplasmic reticulum
KW-0931--ER-Golgi transport
KW-0472--Membrane
KW-0509--mRNA transport
KW-0906--Nuclear pore complex
KW-0539--Nucleus
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0811--Translocation
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005789--C:endoplasmic reticulum membrane
GO:0012507--C:ER to Golgi transport vesicle membrane
GO:0005643--C:nuclear pore
GO:0051028--P:mRNA transport
GO:0015031--P:protein transport
GO:0016192--P:vesicle-mediated transport

KEGG cne:CNI03320
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000671 Aegilops tauschii 44.72 5.00e-70 255.00
IUUC-Aml-001832 Ailuropoda melanoleuca 50.46 3.00e-82 296.00
IUUC-Atr-002914 Amborella trichopoda 43.43 4.00e-67 246.00
IUUC-Apl-003992 Anas platyrhynchos 50.32 1.00e-77 281.00
IUUC-Aca-005283 Anolis carolinensis 51.08 4.00e-82 296.00
IUUC-Aly-005654 Arabidopsis lyrata 44.83 6.00e-68 248.00
IUUC-Ath-006816 Arabidopsis thaliana 44.51 2.00e-67 246.00
IUUC-Ago-007827 Ashbya gossypii 45.82 2.00e-78 283.00
IUUC-Acl-008205 Aspergillus clavatus 53.04 1.00e-80 290.00
IUUC-Afl-008748 Aspergillus flavus 51.84 1.00e-83 300.00
IUUC-Afu-008791 Aspergillus fumigatus 52.72 7.00e-80 288.00
IUUC-Ani-009152 Aspergillus nidulans 51.23 8.00e-82 294.00
IUUC-Ang-009765 Aspergillus niger 52.53 4.00e-82 295.00
IUUC-Aor-009927 Aspergillus oryzae 52.56 1.00e-80 290.00
IUUC-Ate-010248 Aspergillus terreus 52.45 9.00e-84 301.00
IUUC-Ame-011478 Astyanax mexicanus 48.62 1.00e-81 293.00
IUUC-Bgr-012276 Blumeria graminis 51.61 3.00e-78 283.00
IUUC-Bta-012700 Bos taurus 49.85 5.00e-81 292.00
IUUC-Bci-013722 Botrytis cinerea 50.79 1.00e-81 294.00
IUUC-Bdi-014818 Brachypodium distachyon 45.03 2.00e-70 256.00
IUUC-Bol-015779 Brassica oleracea 45.45 1.00e-68 250.00
IUUC-Bra-016973 Brassica rapa 45.77 4.00e-68 250.00
IUUC-Cel-018479 Caenorhabditis elegans 35.13 7.00e-51 192.00
IUUC-Cja-019956 Callithrix jacchus 49.51 1.00e-74 271.00
IUUC-Cfa-020752 Canis familiaris 50.46 4.00e-82 295.00
IUUC-Cpo-021871 Cavia porcellus 50.15 6.00e-82 295.00
IUUC-Cre-022797 Chlamydomonas reinhardtii 48.12 3.00e-77 279.00
IUUC-Csa-023393 Chlorocebus sabaeus 50.15 3.00e-81 293.00
IUUC-Cho-024786 Choloepus hoffmanni 37.96 2.00e-51 194.00
IUUC-Cin-025332 Ciona intestinalis 48.92 8.00e-79 285.00
IUUC-Csv-025926 Ciona savignyi 48.92 5.00e-78 282.00
IUUC-Cgl-026413 Colletotrichum gloeosporioides 51.77 2.00e-78 283.00
IUUC-Cme-027165 Cyanidioschyzon merolae 37.50 7.00e-48 183.00
IUUC-Dre-027782 Danio rerio 49.23 2.00e-82 296.00
IUUC-Dno-029628 Dasypus novemcinctus 51.08 5.00e-83 298.00
IUUC-Dor-030650 Dipodomys ordii 51.81 5.00e-64 236.00
IUUC-Dse-031206 Dothistroma septosporum 50.63 1.00e-80 290.00
IUUC-Dme-031854 Drosophila melanogaster 46.37 4.00e-71 259.00
IUUC-Ete-032618 Echinops telfairi 38.57 5.00e-30 122.00
IUUC-Eca-033268 Equus caballus 50.15 7.00e-82 295.00
IUUC-Fca-035918 Felis catus 50.77 3.00e-82 296.00
IUUC-Fal-037551 Ficedula albicollis 50.47 2.00e-71 260.00
IUUC-Fox-037763 Fusarium oxysporum 52.63 2.00e-86 310.00
IUUC-Fso-038341 Fusarium solani 52.68 3.00e-82 296.00
IUUC-Gmo-038638 Gadus morhua 48.95 8.00e-82 295.00
IUUC-Ggr-039865 Gaeumannomyces graminis 51.23 7.00e-78 281.00
IUUC-Gga-040193 Gallus gallus 51.38 2.00e-82 297.00
IUUC-Gac-041337 Gasterosteus aculeatus 30.00 2.00e-35 141.00
IUUC-Gma-044311 Glycine max 44.51 6.00e-68 249.00
IUUC-Ggo-045252 Gorilla gorilla 50.46 1.00e-81 295.00
IUUC-Hsa-046565 Homo sapiens 50.46 1.00e-81 294.00
IUUC-Hvu-047835 Hordeum vulgare 45.34 4.00e-71 259.00
IUUC-Itr-048587 Ictidomys tridecemlineatus 50.15 1.00e-81 294.00
IUUC-Kpa-049148 Komagataella pastoris 49.84 3.00e-85 306.00
IUUC-Lch-050421 Latimeria chalumnae 50.31 1.00e-82 298.00
IUUC-Lpe-051187 Leersia perrieri 43.65 3.00e-67 249.00
IUUC-Loc-052167 Lepisosteus oculatus 49.23 3.00e-83 300.00
IUUC-Lma-053250 Leptosphaeria maculans 50.78 1.00e-78 284.00
IUUC-Laf-054304 Loxodonta africana 51.08 8.00e-83 298.00
IUUC-Mcc-055519 Macaca mulatta 50.15 5.00e-81 292.00
IUUC-Meu-056439 Macropus eugenii 49.54 8.00e-81 291.00
IUUC-Mor-057241 Magnaporthe oryzae 51.42 2.00e-77 280.00
IUUC-Mpo-057373 Magnaporthe poae 42.15 1.00e-54 203.00
IUUC-Mtr-058412 Medicago truncatula 44.83 1.00e-68 250.00
IUUC-Mla-058966 Melampsora laricipopulina 52.63 1.00e-98 350.00
IUUC-Mga-060066 Meleagris gallopavo 50.32 1.00e-77 281.00
IUUC-Mvi-060290 Microbotryum violaceum 51.78 7.00e-90 324.00
IUUC-Mmr-060717 Microcebus murinus 50.15 1.00e-81 294.00
IUUC-Mdo-062496 Monodelphis domestica 49.85 3.00e-81 292.00
IUUC-Mmu-063490 Mus musculus 50.15 8.00e-82 295.00
IUUC-Mac-065307 Musa acuminata 44.72 7.00e-68 249.00
IUUC-Mpu-066601 Mustela putorius furo 50.46 4.00e-82 295.00
IUUC-Mlu-067501 Myotis lucifugus 50.46 6.00e-82 295.00
IUUC-Nfi-068360 Neosartorya fischeri 51.09 1.00e-65 240.00
IUUC-Ncr-068928 Neurospora crassa 51.38 2.00e-81 293.00
IUUC-Nle-069028 Nomascus leucogenys 50.15 1.00e-81 294.00
IUUC-Opr-070446 Ochotona princeps 49.37 3.00e-77 279.00
IUUC-Ont-071587 Oreochromis niloticus 49.10 1.00e-82 297.00
IUUC-Oan-073211 Ornithorhynchus anatinus 49.54 2.00e-80 290.00
IUUC-Ocu-074306 Oryctolagus cuniculus 50.46 4.00e-81 292.00
IUUC-Oba-075069 Oryza barthii 44.10 1.00e-69 254.00
IUUC-Obr-076667 Oryza brachyantha 44.10 3.00e-70 256.00
IUUC-Ogl-077208 Oryza glaberrima 44.10 1.00e-69 254.00
IUUC-Ogu-078513 Oryza glumaepatula 44.10 1.00e-69 254.00
IUUC-Oin-079094 Oryza indica 44.10 1.00e-69 254.00
IUUC-Olo-080473 Oryza longistaminata 44.10 1.00e-69 254.00
IUUC-Ome-081643 Oryza meridionalis 44.10 1.00e-69 254.00
IUUC-Oni-082589 Oryza nivara 44.10 1.00e-69 254.00
IUUC-Opu-083677 Oryza punctata 44.10 1.00e-69 254.00
IUUC-Oru-084537 Oryza rufipogon 44.10 1.00e-69 254.00
IUUC-Osa-085449 Oryza sativa 44.10 1.00e-69 254.00
IUUC-Ola-087226 Oryzias latipes 49.07 9.00e-82 294.00
IUUC-Olu-087893 Ostreococcus lucimarinus 43.45 8.00e-64 234.00
IUUC-Oga-088837 Otolemur garnettii 50.15 2.00e-81 294.00
IUUC-Oar-089594 Ovis aries 50.46 1.00e-81 294.00
IUUC-Ptr-091132 Pan troglodytes 50.46 8.00e-82 295.00
IUUC-Pan-092013 Papio anubis 27.76 5.00e-27 112.00
IUUC-Psi-093568 Pelodiscus sinensis 50.16 1.00e-78 283.00
IUUC-Pma-094756 Petromyzon marinus 49.60 3.00e-30 121.00
IUUC-Pno-094955 Phaeosphaeria nodorum 48.43 4.00e-75 272.00
IUUC-Ppa-095835 Physcomitrella patens 44.06 3.00e-66 243.00
IUUC-Pfo-096063 Poecilia formosa 49.69 1.00e-82 297.00
IUUC-Pab-098674 Pongo abelii 50.46 3.00e-81 293.00
IUUC-Pop-099868 Populus trichocarpa 44.51 2.00e-66 243.00
IUUC-Pca-100824 Procavia capensis 38.15 2.00e-52 197.00
IUUC-Ppe-101278 Prunus persica 43.89 6.00e-66 241.00
IUUC-Pva-103161 Pteropus vampyrus 48.00 5.00e-76 275.00
IUUC-Pgr-103573 Puccinia graminis 54.41 5.00e-96 342.00
IUUC-Ptt-103700 Puccinia triticina 52.81 3.00e-89 319.00
IUUC-Pte-104267 Pyrenophora teres 48.59 3.00e-75 273.00
IUUC-Pyt-104535 Pyrenophora triticirepentis 48.58 9.00e-74 268.00
IUUC-Rno-104833 Rattus norvegicus 50.15 9.00e-82 294.00
IUUC-Sce-106437 Saccharomyces cerevisiae 46.86 2.00e-74 270.00
IUUC-Sha-106611 Sarcophilus harrisii 49.54 8.00e-81 291.00
IUUC-Sja-107654 Schizosaccharomyces japonicus 49.54 1.00e-88 317.00
IUUC-Spo-108362 Schizosaccharomyces pombe 50.31 2.00e-86 310.00
IUUC-Smo-108797 Selaginella moellendorffii 45.82 4.00e-69 252.00
IUUC-Sit-110132 Setaria italica 44.72 1.00e-69 254.00
IUUC-Sly-111852 Solanum lycopersicum 43.57 3.00e-67 246.00
IUUC-Stu-112195 Solanum tuberosum 43.26 6.00e-67 245.00
IUUC-Sar-113279 Sorex araneus 27.92 3.00e-25 107.00
IUUC-Sbi-114229 Sorghum bicolor 44.41 1.00e-69 254.00
IUUC-Sre-114898 Sporisorium reilianum 53.22 1.00e-103 367.00
IUUC-Ssc-115995 Sus scrofa 55.06 2.00e-43 166.00
IUUC-Tgu-116793 Taeniopygia guttata 50.15 9.00e-75 271.00
IUUC-Tru-117797 Takifugu rubripes 49.10 1.00e-82 297.00
IUUC-Tsy-118913 Tarsius syrichta 27.76 8.00e-23 99.00
IUUC-Tni-120366 Tetraodon nigroviridis 49.25 7.00e-83 298.00
IUUC-Tca-121242 Theobroma cacao 43.89 2.00e-66 243.00
IUUC-Tre-121899 Trichoderma reesei 53.18 3.00e-84 303.00
IUUC-Tvi-122380 Trichoderma virens 53.02 5.00e-83 298.00
IUUC-Tae-124286 Triticum aestivum 45.65 2.00e-71 260.00
IUUC-Tur-126202 Triticum urartu 45.34 2.00e-71 259.00
IUUC-Tme-127181 Tuber melanosporum 48.15 6.00e-80 289.00
IUUC-Ttr-128448 Tursiops truncatus 47.81 2.00e-62 230.00
IUUC-Uma-129661 Ustilago maydis 52.41 7.00e-104 368.00
IUUC-Vda-129666 Verticillium dahliae 49.52 7.00e-78 281.00
IUUC-Vpa-130318 Vicugna pacos 50.46 1.00e-81 294.00
IUUC-Vvi-130868 Vitis vinifera 45.14 1.00e-68 251.00
IUUC-Xtr-131859 Xenopus tropicalis 50.77 5.00e-83 298.00
IUUC-Xma-133898 Xiphophorus maculatus 49.54 3.00e-82 296.00
IUUC-Yli-134559 Yarrowia lipolytica 51.10 1.00e-81 293.00
Created Date 25-Jun-2017

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