iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004729

UUCD1 version

UUC-AnC-00034

Ensembl Protein ID

ENSACAP00000014425.2

UniProt Accession

H9GLD1; H9GLD1_ANOCA

Protein Name

Uncharacterized protein

Gene Name

KLHL25

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000014718.2	ENSACAT00000014720.2	ENSACAP00000014425.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	2.20e-19	69.5	46	114
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	2.80e-09	36.2	146	177

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikd.vqpevfrallkFlYtgkldene 69
           +Dv+l  g++ f++h++vLaasS++F+a+f+++l+es  +++v+++d + pev++ ll++ Y++k+ +ne
   Q: 46   TDVTLWAGNKSFPCHRAVLAASSRYFEAMFSNGLRESL-GDEVNFHDsLHPEVLELLLDYAYSSKIIINE 114
           7************************************9.*******99*****************99987 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           ++Nclg++ ++d+++c +L++   +++l +F+
   Q: 146  PSNCLGMMVLSDAHQCKRLYELSWRMCLVNFE 177
           89****************************95 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MSVSVHENRK SRTSTGSMNI LLFHKASHPD CVLSHLNTMR KHCTFTDVTL WAGNKSFPCH 60
RAVLAASSRY FEAMFSNGLR ESLGDEVNFH DSLHPEVLEL LLDYAYSSKI IINEENAESL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCAGTCA GCGTCCACGA GAACCGTAAA TCCCGGACCA GTACTGGTTC TATGAACATC 60
CTGCTGTTCC ATAAAGCTTC CCACCCAGAT TGTGTCCTCT CACATCTCAA CACCATGAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015916--Gal_Oxidase_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030565--KLHL25
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0006446--P:regulation of translational initiation

KEGG

acs:100560014

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002373	Ailuropoda melanoleuca	87.61	0.00e+00	1110.00
IUUC-Apl-003543	Anas platyrhynchos	91.69	0.00e+00	1116.00
IUUC-Ame-011020	Astyanax mexicanus	84.04	0.00e+00	1031.00
IUUC-Bta-012955	Bos taurus	85.91	0.00e+00	1092.00
IUUC-Cja-018839	Callithrix jacchus	86.76	0.00e+00	1097.00
IUUC-Cfa-020224	Canis familiaris	87.61	0.00e+00	1108.00
IUUC-Cpo-021593	Cavia porcellus	84.38	0.00e+00	1029.00
IUUC-Csa-023276	Chlorocebus sabaeus	87.44	0.00e+00	1105.00
IUUC-Dre-028053	Danio rerio	84.04	0.00e+00	1006.00
IUUC-Dno-029287	Dasypus novemcinctus	85.57	0.00e+00	1085.00
IUUC-Dor-030908	Dipodomys ordii	79.29	0.00e+00	982.00
IUUC-Dse-031490	Dothistroma septosporum	26.71	7.00e-05	40.80
IUUC-Fca-035897	Felis catus	87.44	0.00e+00	1107.00
IUUC-Fal-037036	Ficedula albicollis	92.19	0.00e+00	1127.00
IUUC-Gmo-039345	Gadus morhua	82.85	0.00e+00	986.00
IUUC-Gga-040404	Gallus gallus	91.68	0.00e+00	1120.00
IUUC-Gac-042447	Gasterosteus aculeatus	83.02	0.00e+00	1004.00
IUUC-Ggo-045060	Gorilla gorilla	87.44	0.00e+00	1105.00
IUUC-Hsa-046494	Homo sapiens	87.61	0.00e+00	1107.00
IUUC-Itr-047993	Ictidomys tridecemlineatus	87.95	0.00e+00	1107.00
IUUC-Lch-050211	Latimeria chalumnae	85.71	0.00e+00	1051.00
IUUC-Loc-052578	Lepisosteus oculatus	83.87	0.00e+00	1036.00
IUUC-Laf-053498	Loxodonta africana	87.44	0.00e+00	1057.00
IUUC-Mcc-055033	Macaca mulatta	87.27	0.00e+00	1104.00
IUUC-Meu-056893	Macropus eugenii	89.98	0.00e+00	1125.00
IUUC-Mga-060025	Meleagris gallopavo	92.02	0.00e+00	1124.00
IUUC-Mmr-060658	Microcebus murinus	86.76	0.00e+00	1102.00
IUUC-Mdo-062667	Monodelphis domestica	89.81	0.00e+00	1122.00
IUUC-Mmu-063125	Mus musculus	86.25	0.00e+00	1054.00
IUUC-Mpu-066209	Mustela putorius furo	87.27	0.00e+00	1106.00
IUUC-Mlu-068237	Myotis lucifugus	85.57	0.00e+00	1058.00
IUUC-Nle-069454	Nomascus leucogenys	87.31	0.00e+00	1091.00
IUUC-Ont-072138	Oreochromis niloticus	83.87	0.00e+00	995.00
IUUC-Oan-073320	Ornithorhynchus anatinus	81.83	0.00e+00	1037.00
IUUC-Ocu-073765	Oryctolagus cuniculus	82.51	0.00e+00	1031.00
IUUC-Oga-088002	Otolemur garnettii	86.76	0.00e+00	1093.00
IUUC-Oar-089481	Ovis aries	85.40	0.00e+00	1088.00
IUUC-Ptr-091200	Pan troglodytes	87.61	0.00e+00	1104.00
IUUC-Psi-093884	Pelodiscus sinensis	92.02	0.00e+00	1117.00
IUUC-Pva-102321	Pteropus vampyrus	86.42	0.00e+00	1092.00
IUUC-Rno-104835	Rattus norvegicus	86.25	0.00e+00	1054.00
IUUC-Sha-107528	Sarcophilus harrisii	89.98	0.00e+00	1126.00
IUUC-Ssc-116161	Sus scrofa	87.27	0.00e+00	1103.00
IUUC-Tgu-116569	Taeniopygia guttata	92.02	0.00e+00	1123.00
IUUC-Tni-120525	Tetraodon nigroviridis	74.32	0.00e+00	870.00
IUUC-Ttr-129297	Tursiops truncatus	86.93	0.00e+00	1101.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence