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Tag Content
UUCD2 ID IUUC-Aml-001901
UUCD1 version UUC-AiM-00551
Ensembl Protein ID ENSAMEP00000009679.1
UniProt Accession G1LRJ4; G1LRJ4_AILME
Genbank Protein ID ENSAMEP00000009679
Protein Name Uncharacterized protein
Genbank Nucleotide ID ACTA01172027
Gene Name PML
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSAMEG00000009174.1 ENSAMET00000010096.1 ENSAMEP00000009679.1
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 activity/RING/RING 79.71 0.00e+00 1242.00 IUUC-Hsa-045861
E3 activity/RING/RING 67.09 0.00e+00 984.00 IUUC-Mmu-063118
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Ailuropoda melanoleuca
Protein Sequence
(Fasta)
QEPAPARSPG PQQDPALPHT PTMPPPESVP EGHQPSPSHS PTEERGQAFE EEFQFLRCQG 60
CQAEAKCPKL LPCLHTLCSG CLKAPDMRCP ICQAPGPLGA DSLALDNVFF ESLQRRLSVY 120
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Protein Fasta Sequence



>IUUC-Aml-001901|E3,RING|Ailuropoda melanoleuca
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Nucleotide Sequence
(Fasta)
CAAGAGCCTG CACCCGCCCG ATCTCCAGGT CCCCAGCAAG ACCCCGCACT TCCCCACACG 60
CCCACCATGC CTCCCCCGGA GTCCGTCCCC GAAGGCCACC AGCCCAGCCC CAGCCACAGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Aml-001901|E3,RING|Ailuropoda melanoleuca
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR021978--DUF3583
IPR012337--RNaseH-like_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF12126--DUF3583
PF00643--zf-B_box

SMART

SM00336--BBOX
SM00184--RING

Gene Ontology

GO:0005829--C:cytosol
GO:0042406--C:extrinsic component of endoplasmic reticulum membrane
GO:0000784--C:nuclear chromosome, telomeric region
GO:0016363--C:nuclear matrix
GO:0031965--C:nuclear membrane
GO:0005730--C:nucleolus
GO:0016605--C:PML body
GO:0008270--F:zinc ion binding
GO:0006919--P:activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0060444--P:branching involved in mammary gland duct morphogenesis
GO:0007050--P:cell cycle arrest
GO:0045165--P:cell fate commitment
GO:0071353--P:cellular response to interleukin-4
GO:0090398--P:cellular senescence
GO:0032922--P:circadian regulation of gene expression
GO:0007182--P:common-partner SMAD protein phosphorylation
GO:0006977--P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0032469--P:endoplasmic reticulum calcium ion homeostasis
GO:0043153--P:entrainment of circadian clock by photoperiod
GO:0097191--P:extrinsic apoptotic signaling pathway
GO:0010761--P:fibroblast migration
GO:0045087--P:innate immune response
GO:0042771--P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0070059--P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0008631--P:intrinsic apoptotic signaling pathway in response to oxidative stress
GO:0051457--P:maintenance of protein location in nucleus
GO:0030099--P:myeloid cell differentiation
GO:0016525--P:negative regulation of angiogenesis
GO:0030308--P:negative regulation of cell growth
GO:0008285--P:negative regulation of cell proliferation
GO:0050713--P:negative regulation of interleukin-1 beta secretion
GO:2000059--P:negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:1902187--P:negative regulation of viral release from host cell
GO:0030578--P:PML body organization
GO:2001238--P:positive regulation of extrinsic apoptotic signaling pathway
GO:0048146--P:positive regulation of fibroblast proliferation
GO:0045345--P:positive regulation of MHC class I biosynthetic process
GO:0032206--P:positive regulation of telomere maintenance
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0006461--P:protein complex assembly
GO:0010522--P:regulation of calcium ion transport into cytosol
GO:0030155--P:regulation of cell adhesion
GO:2000779--P:regulation of double-strand break repair
GO:0001932--P:regulation of protein phosphorylation
GO:0010332--P:response to gamma radiation
GO:0001666--P:response to hypoxia
GO:0009411--P:response to UV
GO:0048384--P:retinoic acid receptor signaling pathway
GO:0007184--P:SMAD protein import into nucleus
GO:0007179--P:transforming growth factor beta receptor signaling pathway

Orthology
iUUCD ID Species Identity E-value Score
IUUC-Bta-012427 Bos taurus 74.80 0.00e+00 1192.00
IUUC-Cja-019029 Callithrix jacchus 78.82 0.00e+00 1230.00
IUUC-Cfa-021127 Canis familiaris 80.32 0.00e+00 1254.00
IUUC-Cpo-022553 Cavia porcellus 66.91 0.00e+00 990.00
IUUC-Csa-023187 Chlorocebus sabaeus 76.05 0.00e+00 822.00
IUUC-Cho-024937 Choloepus hoffmanni 67.11 1.00e-96 347.00
IUUC-Dno-029326 Dasypus novemcinctus 74.06 0.00e+00 1104.00
IUUC-Dor-030808 Dipodomys ordii 60.06 0.00e+00 687.00
IUUC-Ete-032746 Echinops telfairi 53.81 2.00e-178 619.00
IUUC-Eca-033234 Equus caballus 78.42 0.00e+00 1196.00
IUUC-Fca-035648 Felis catus 85.02 0.00e+00 1360.00
IUUC-Ggo-044927 Gorilla gorilla 79.48 0.00e+00 1272.00
IUUC-Hsa-045861 Homo sapiens 79.71 0.00e+00 1276.00
IUUC-Itr-047861 Ictidomys tridecemlineatus 77.64 0.00e+00 1254.00
IUUC-Loc-052276 Lepisosteus oculatus 36.23 6.00e-54 205.00
IUUC-Laf-054059 Loxodonta africana 73.22 0.00e+00 1122.00
IUUC-Meu-056495 Macropus eugenii 54.78 1.00e-103 370.00
IUUC-Mga-059224 Meleagris gallopavo 45.31 5.00e-46 179.00
IUUC-Mmr-061507 Microcebus murinus 73.58 0.00e+00 1134.00
IUUC-Mdo-062196 Monodelphis domestica 46.69 0.00e+00 632.00
IUUC-Mmu-063118 Mus musculus 66.86 0.00e+00 1042.00
IUUC-Mpu-066024 Mustela putorius furo 80.93 0.00e+00 1294.00
IUUC-Mlu-066980 Myotis lucifugus 72.87 0.00e+00 1121.00
IUUC-Nle-069779 Nomascus leucogenys 78.34 0.00e+00 1199.00
IUUC-Ocu-074016 Oryctolagus cuniculus 65.35 0.00e+00 986.00
IUUC-Oga-089085 Otolemur garnettii 65.88 0.00e+00 1028.00
IUUC-Oar-089980 Ovis aries 72.25 0.00e+00 1122.00
IUUC-Ptr-091681 Pan troglodytes 79.41 0.00e+00 1269.00
IUUC-Pan-091965 Papio anubis 76.76 0.00e+00 1176.00
IUUC-Psi-093577 Pelodiscus sinensis 36.47 1.00e-111 397.00
IUUC-Pab-098215 Pongo abelii 74.63 2.00e-177 616.00
IUUC-Pca-100883 Procavia capensis 69.17 0.00e+00 786.00
IUUC-Pva-102465 Pteropus vampyrus 73.67 0.00e+00 813.00
IUUC-Rno-105120 Rattus norvegicus 66.71 0.00e+00 1087.00
IUUC-Sar-113320 Sorex araneus 63.19 2.00e-88 320.00
IUUC-Ssc-116042 Sus scrofa 75.68 0.00e+00 1201.00
IUUC-Tbe-127880 Tupaia belangeri 66.63 0.00e+00 875.00
Created Date 25-Jun-2017

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