iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bta-013198

Ensembl Protein ID

ENSBTAP00000021597.4

UniProt Accession

F1N1C9; F1N1C9_BOVIN

Genbank Protein ID

ENSBTAP00000021597

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02072255

Gene Name

BRWD3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000016230.4	ENSBTAT00000021597.4	ENSBTAP00000021597.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.90e-30	102.2	35	72
UBD/Beta-Prp	2.20e-52	178.2	138	396

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlrtgvll 36
           gH +sv+c+af  s++++ +GsdD+ +k+W +++g+ll
   Q: 35   GHLSSVYCVAFdrSGRRIFTGSDDCLVKIWATDDGRLL 72
           8**********96669******************9987 PP

UBD/Beta-Prp

   S: 23   sllatgsrdgtikvwdvttgkl......lrslsgheae..........vtavkfspdgkilvtgseDrtikvw..dlstgkcvhtlkgh 93
           ++l+++++dgti  w+++ +++      +        +          +++ +fs+ g ++ tgs+D++i+++    + ++ +  l+ h
   Q: 138  RYLTSTGADGTICFWQWHVKTMkfkdrpV--------KftersrpgvqISCSSFSSGGMFITTGSTDHVIRIYylGSEIPEKIAELESH 218
           79*************99987775566652........2333334445699***********************7777899********* PP
   S: 94   edsvlslsfspsg..dklvsGshdrtirvwdletgqclee................tlsghdgvvncvvvhpdgnllvsGslDrtvrlW 164
           +d+v++++f+ +g   ++vsGs+d t+r+w+ +++++ +                  +++++  v++v+++  +  ++++ ++  +++W
   Q: 219  TDKVVAVQFCNNGdsLRFVSGSRDGTARIWQYQQQEWKSIvldmatkmtgnnlpsgEDKVTKLKVTMVAWDRYDTTVITAVNNFLLKVW 307
           ***********8832468*******************999************999888888899************************* PP
   S: 165  dlktgkllrtltgghtdsvysls...fdsngkelvsgsldgtvklwdlqtgecvrtlnght.....dnvksvrfspnderlvsgssDgs 245
           ++ tg+ll+tl+g h+d v  l+   fd+  + ++s+++dg + +wdl +g+ +r + +         v + +fsp++++++++ s+g 
   Q: 308  NSITGQLLHTLSG-HDDEVFVLEahpFDQ--RIILSAGHDGNIFVWDLDRGTKIRNYFNMIegqghGAVFDCKFSPDGNHFACTDSHGH 393
           ************9.*********555555..99********************98887755455567788899999***9999999988 PP
   S: 246  iri 248
           + +
   Q: 394  LLL 396
           766 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

VNITSARQLT GCSRFSHIFP SAAYQHIKMH KRILGHLSSV YCVAFDRSGR RIFTGSDDCL 60
VKIWATDDGR LLATLRGHSA EISDMAVNYE NTLIAAGSCD KVVRVWCLRT CAPVAVLQGH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGAATATCA CCTCAGCCAG GCAATTAACC GGATGTAGTC GTTTCAGCCA TATTTTCCCT 60
TCAGCTGCTT ACCAGCACAT TAAGATGCAT AAGAGAATTC TGGGTCACTT GTCATCTGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR001487--Bromodomain
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0007010--P:cytoskeleton organization
GO:0008360--P:regulation of cell shape
GO:0006357--P:regulation of transcription from RNA polymerase II promoter

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001881	Ailuropoda melanoleuca	96.50	0.00e+00	2867.00
IUUC-Apl-004016	Anas platyrhynchos	81.78	0.00e+00	2129.00
IUUC-Aca-004722	Anolis carolinensis	77.90	0.00e+00	2222.00
IUUC-Cfa-020963	Canis familiaris	95.65	0.00e+00	2849.00
IUUC-Cpo-022448	Cavia porcellus	86.32	0.00e+00	2527.00
IUUC-Csa-023166	Chlorocebus sabaeus	95.51	0.00e+00	2700.00
IUUC-Cin-025553	Ciona intestinalis	39.31	2.00e-114	407.00
IUUC-Dre-028508	Danio rerio	66.52	0.00e+00	1691.00
IUUC-Dno-030070	Dasypus novemcinctus	92.46	0.00e+00	2726.00
IUUC-Dor-031052	Dipodomys ordii	86.01	0.00e+00	1343.00
IUUC-Ete-032650	Echinops telfairi	89.16	0.00e+00	1689.00
IUUC-Eca-033953	Equus caballus	96.93	0.00e+00	2806.00
IUUC-Eeu-034871	Erinaceus europaeus	79.73	0.00e+00	1091.00
IUUC-Fca-036099	Felis catus	95.95	0.00e+00	2874.00
IUUC-Fal-037246	Ficedula albicollis	80.54	0.00e+00	2284.00
IUUC-Gga-041097	Gallus gallus	82.44	0.00e+00	2343.00
IUUC-Gac-042435	Gasterosteus aculeatus	65.48	0.00e+00	1679.00
IUUC-Hsa-045666	Homo sapiens	95.51	0.00e+00	2700.00
IUUC-Loc-051802	Lepisosteus oculatus	69.60	0.00e+00	1889.00
IUUC-Laf-053942	Loxodonta africana	95.18	0.00e+00	2709.00
IUUC-Mcc-054645	Macaca mulatta	95.64	0.00e+00	2705.00
IUUC-Meu-056321	Macropus eugenii	74.48	0.00e+00	930.00
IUUC-Mga-060063	Meleagris gallopavo	82.48	0.00e+00	2331.00
IUUC-Mmr-061262	Microcebus murinus	95.91	0.00e+00	2711.00
IUUC-Mdo-062320	Monodelphis domestica	74.15	0.00e+00	2051.00
IUUC-Mmu-063163	Mus musculus	93.30	0.00e+00	2753.00
IUUC-Mpu-066628	Mustela putorius furo	96.02	0.00e+00	2854.00
IUUC-Mlu-068082	Myotis lucifugus	95.97	0.00e+00	2685.00
IUUC-Nle-069609	Nomascus leucogenys	95.51	0.00e+00	2719.00
IUUC-Ont-071589	Oreochromis niloticus	66.49	0.00e+00	1667.00
IUUC-Ocu-074122	Oryctolagus cuniculus	93.89	0.00e+00	2133.00
IUUC-Ola-086580	Oryzias latipes	66.46	0.00e+00	1705.00
IUUC-Oga-089053	Otolemur garnettii	95.35	0.00e+00	2836.00
IUUC-Oar-090042	Ovis aries	99.34	0.00e+00	2964.00
IUUC-Ptr-091268	Pan troglodytes	95.71	0.00e+00	2706.00
IUUC-Pan-092376	Papio anubis	95.64	0.00e+00	2706.00
IUUC-Psi-093408	Pelodiscus sinensis	81.08	0.00e+00	2382.00
IUUC-Pfo-096515	Poecilia formosa	66.19	0.00e+00	1613.00
IUUC-Pab-097672	Pongo abelii	95.52	0.00e+00	2734.00
IUUC-Pva-102512	Pteropus vampyrus	97.25	0.00e+00	2085.00
IUUC-Rno-105797	Rattus norvegicus	93.52	0.00e+00	2647.00
IUUC-Sha-107061	Sarcophilus harrisii	76.57	0.00e+00	2178.00
IUUC-Sar-113004	Sorex araneus	84.21	0.00e+00	1665.00
IUUC-Tgu-117254	Taeniopygia guttata	81.45	0.00e+00	2288.00
IUUC-Tru-118186	Takifugu rubripes	66.11	0.00e+00	1694.00
IUUC-Tsy-119003	Tarsius syrichta	90.07	0.00e+00	2501.00
IUUC-Tni-120110	Tetraodon nigroviridis	65.95	0.00e+00	1656.00
IUUC-Tbe-127813	Tupaia belangeri	76.77	0.00e+00	923.00
IUUC-Ttr-129265	Tursiops truncatus	95.38	0.00e+00	2677.00
IUUC-Vpa-130736	Vicugna pacos	90.69	0.00e+00	1510.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence