iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000018027.8	ENSRNOT00000024491.7	ENSRNOP00000024491.4
ENSRNOG00000018027.8	ENSRNOT00000058652.4	ENSRNOP00000055446.3

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.20e-41	137.9	508	543
UBD/Beta-Prp	1.30e-67	228.4	271	570

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgv 34
           gHtds+t+laf +d +l++s+s D++++vWD+r+  
   Q: 508  GHTDSITSLAFsPDsGLIASASMDNSVRVWDIRSTC 543
           8***********999****************98765 PP

UBD/Beta-Prp

   S: 13   itcvkfspdksllatgsrdgtikvwdvttgkl................................lrslsgheaevtavkfspdgkilvt 69
           ++   +s d++lla+g+++++ik+w+++++kl                                ++ l gh ++v++++f  d++ l++
   Q: 271  LNTAEISSDSKLLAAGFDNSCIKLWSLRSKKLksephcvdtsrvrlacdtleeeesedddvgteMKILRGHCGPVYSTRFLADSSGLLS 359
           55567889********************************************************9************************ PP
   S: 70   gseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslD 158
           +seD+ i+ wdl +++ ++ ++gh + v+++++sp++ +++sGshdrt+r+w  +  + l+ + +gh + v cv++hp++n+l++Gs+D
   Q: 360  CSEDMSIRYWDLGSFTNTVLYQGHAYPVWDVDISPYSLYFASGSHDRTARLWSFDRTYPLR-IYAGHLADVDCVKFHPNSNYLATGSTD 447
           *************************************************************.*************************** PP
   S: 159  rtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsir 247
           +tvrlW+ ++g+ +r +tg h ++v slsf++ngk+l+s+++d+++klwdl +g+  ++l+ghtd ++s++fsp++ +++s+s+D+s+r
   Q: 448  KTVRLWSAQQGNSVRLFTG-HRGPVLSLSFSPNGKYLASAGEDQRLKLWDLASGTLFKELRGHTDSITSLAFSPDSGLIASASMDNSVR 535
           ******************9.********************************************************************* PP
   S: 248  iWdlrsgdllktlqlhn...........ssvisva 271
           +Wd+rs  +++   ++            s+v sv+
   Q: 536  VWDIRSTCCNTPADGSSgelvgvytgqmSNVLSVQ 570
           **999988888777777333333333334444444 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MKRVRTEQVQ VAVSCYLKRR QYVDSEGPLK QGLRLSQTPE EMAANLTVQS ESGCANAVSA 60
APCQAEPQQY EVQFGRLRNF LTDSDSQYSH EVMPLLYPLF VYLHLNLVQS GPKSTVESFY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCAAAACCAA GAAGCCATGG GAGGAAGAGA TAGCCAGACT GAGATTTGTC CACACCAGGT 60
GAGCATTTGT GAGGGTGCCT CCAAAGGAGA GGGATTGGCC AAAGCCTACG TAAAAGGTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR023302--Pept_S9A_N
IPR007582--TFIID_NTD2
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04494--TFIID_NTD2
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002016	Ailuropoda melanoleuca	93.38	0.00e+00	1064.00
IUUC-Apl-003636	Anas platyrhynchos	89.85	0.00e+00	1079.00
IUUC-Aca-004229	Anolis carolinensis	88.96	0.00e+00	1045.00
IUUC-Ame-010599	Astyanax mexicanus	66.23	0.00e+00	806.00
IUUC-Bta-013404	Bos taurus	89.64	0.00e+00	1014.00
IUUC-Cja-019643	Callithrix jacchus	93.38	0.00e+00	1067.00
IUUC-Cfa-020913	Canis familiaris	93.55	0.00e+00	1065.00
IUUC-Cpo-021777	Cavia porcellus	93.89	0.00e+00	1073.00
IUUC-Csa-024184	Chlorocebus sabaeus	93.38	0.00e+00	1069.00
IUUC-Cho-024638	Choloepus hoffmanni	93.55	0.00e+00	1057.00
IUUC-Cin-025618	Ciona intestinalis	35.13	1.00e-90	327.00
IUUC-Csv-025874	Ciona savignyi	42.58	6.00e-78	285.00
IUUC-Dre-028817	Danio rerio	66.11	0.00e+00	792.00
IUUC-Dno-029969	Dasypus novemcinctus	86.25	0.00e+00	1010.00
IUUC-Dor-031117	Dipodomys ordii	94.74	0.00e+00	1104.00
IUUC-Ete-032712	Echinops telfairi	85.57	0.00e+00	951.00
IUUC-Eca-033742	Equus caballus	93.21	0.00e+00	1061.00
IUUC-Eeu-035096	Erinaceus europaeus	90.51	0.00e+00	1068.00
IUUC-Fca-035769	Felis catus	92.55	0.00e+00	1079.00
IUUC-Fal-036645	Ficedula albicollis	89.21	0.00e+00	1015.00
IUUC-Fso-038302	Fusarium solani	32.95	3.00e-40	160.00
IUUC-Gmo-038636	Gadus morhua	66.28	0.00e+00	769.00
IUUC-Gga-040144	Gallus gallus	89.64	0.00e+00	1049.00
IUUC-Gac-041716	Gasterosteus aculeatus	67.22	0.00e+00	800.00
IUUC-Ggo-044568	Gorilla gorilla	93.55	0.00e+00	1069.00
IUUC-Hsa-046178	Homo sapiens	93.55	0.00e+00	1069.00
IUUC-Itr-048967	Ictidomys tridecemlineatus	89.47	0.00e+00	1076.00
IUUC-Lch-050501	Latimeria chalumnae	75.71	0.00e+00	837.00
IUUC-Loc-052895	Lepisosteus oculatus	81.47	0.00e+00	629.00
IUUC-Laf-053950	Loxodonta africana	89.64	0.00e+00	1031.00
IUUC-Mcc-055450	Macaca mulatta	93.38	0.00e+00	1065.00
IUUC-Meu-056182	Macropus eugenii	86.25	0.00e+00	990.00
IUUC-Mga-059619	Meleagris gallopavo	89.81	0.00e+00	1053.00
IUUC-Mmr-061074	Microcebus murinus	91.88	0.00e+00	1075.00
IUUC-Mdo-062307	Monodelphis domestica	91.67	0.00e+00	876.00
IUUC-Mmu-063226	Mus musculus	97.62	0.00e+00	1098.00
IUUC-Mpu-066016	Mustela putorius furo	93.38	0.00e+00	1059.00
IUUC-Mlu-067257	Myotis lucifugus	86.14	0.00e+00	1055.00
IUUC-Nle-070139	Nomascus leucogenys	93.72	0.00e+00	1071.00
IUUC-Opr-070243	Ochotona princeps	88.79	0.00e+00	1040.00
IUUC-Ont-072686	Oreochromis niloticus	68.00	0.00e+00	824.00
IUUC-Oan-073670	Ornithorhynchus anatinus	82.49	0.00e+00	818.00
IUUC-Ocu-074525	Oryctolagus cuniculus	93.21	0.00e+00	1088.00
IUUC-Ola-086524	Oryzias latipes	67.67	0.00e+00	838.00
IUUC-Oga-088540	Otolemur garnettii	92.70	0.00e+00	1058.00
IUUC-Oar-089793	Ovis aries	86.76	0.00e+00	951.00
IUUC-Ptr-091154	Pan troglodytes	93.55	0.00e+00	1069.00
IUUC-Pan-092759	Papio anubis	93.38	0.00e+00	1065.00
IUUC-Psi-094008	Pelodiscus sinensis	86.76	0.00e+00	1040.00
IUUC-Pma-094593	Petromyzon marinus	45.84	9.00e-134	470.00
IUUC-Pfo-097409	Poecilia formosa	65.89	0.00e+00	796.00
IUUC-Pab-097946	Pongo abelii	82.00	0.00e+00	915.00
IUUC-Pca-100727	Procavia capensis	86.08	0.00e+00	961.00
IUUC-Pva-103211	Pteropus vampyrus	83.36	0.00e+00	1003.00
IUUC-Ptt-103995	Puccinia triticina	43.07	3.00e-71	263.00
IUUC-Sha-106833	Sarcophilus harrisii	91.22	0.00e+00	1064.00
IUUC-Sar-113381	Sorex araneus	92.70	0.00e+00	1087.00
IUUC-Ssc-116421	Sus scrofa	91.85	0.00e+00	1097.00
IUUC-Tgu-117143	Taeniopygia guttata	89.81	0.00e+00	1080.00
IUUC-Tru-118680	Takifugu rubripes	66.67	0.00e+00	820.00
IUUC-Tsy-119622	Tarsius syrichta	77.59	0.00e+00	810.00
IUUC-Tni-120131	Tetraodon nigroviridis	66.50	0.00e+00	822.00
IUUC-Ttr-129171	Tursiops truncatus	90.66	0.00e+00	1031.00
IUUC-Xtr-132241	Xenopus tropicalis	78.98	0.00e+00	923.00
IUUC-Xma-133554	Xiphophorus maculatus	66.29	0.00e+00	731.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence