iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mcc-055361

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

JSUE03010906

Gene Name

EML6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000021296.3	ENSMMUT00000029973.3	ENSMMUP00000028052.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.30e-49	162.7	1446	1478
UBD/Beta-Prp	1.30e-113	380.3	483	701

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 4    dsvtclaf.sd.tllvsGsdDgtikvWDlrtgv 34
           +++++la  ++ +l++s+s+Dgt ++WDl + +
   Q: 1446 GEIWGLAThPSkDLFISASNDGTARIWDLADKK 1478
           4688888887779***************98765 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatg..srdgtikvwdvttgkllrsl.sgheaevtavkfspdgkilvtgseD..rtikvwdlstgkcvhtl 90
           gh+++ ++ ++++p k+++atg  +rd+ i vwd++t k+l+ l  +h+ +v a++fs dgk lv+++ D  + i  wd ++g+ + t 
   Q: 483  GHDDDILS-LTIHPVKDYVATGqvGRDAAIHVWDTQTLKCLSLLkGQHQRGVCALDFSADGKCLVSVGLDdfHSIVFWDWKKGEKIATT 570
           45555555.99999999999995569999999999999999999777999999999999999999999997777888999999999999 PP
   S: 91   kghedsvlslsfspsg.dklvsGshdrtirvwdletgqclee....tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrt 174
           +gh+d++  ++ +p   dklv+ +  + i+ w+   g   ++       g+ ++ +cv++   ++l++sG++ + + +W  k   ll+t
   Q: 571  RGHKDKIFVVKCNPHHvDKLVTVG-IKHIKFWQQAGGGFTSKrgtfGSIGKLETMMCVSYGRMEDLVFSGAATGDIFIW--KDILLLKT 656
           999999999999997768888887.999999988888777778876666888899999999999999999999999999..78999999 PP
   S: 175  ltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnght 222
            +  h+++v  +   +  k +v+g++dg v+lwd   ++c++t+   +
   Q: 657  VKA-HDGPVFAMYALD--KGFVTGGKDGIVELWDDMFERCLKTYAIKR 701
           997.999999999888..579999999999999999999999997655 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MYACEEGFAT GGRDGCIRLW DTDFKPITKI DLRETEQGYK GLSIRSVCWK ADRLLAGTQD 60
SEIFEVIVRE RDKPMLILQG HCEGELWALA LHPKKPLAVT GSDDRSVRLW SLADHALIAR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTATGCTT GTGAAGAAGG CTTTGCCACT GGTGGGCGAG ATGGGTGTAT ACGACTATGG 60
GACACTGATT TCAAACCAAT AACCAAAATT GATCTCAGGG AGACAGAACA AGGATATAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR005108--HELP
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001387	Ailuropoda melanoleuca	98.02	0.00e+00	3389.00
IUUC-Apl-003604	Anas platyrhynchos	93.68	0.00e+00	3231.00
IUUC-Aca-004572	Anolis carolinensis	89.19	0.00e+00	3125.00
IUUC-Bta-012812	Bos taurus	97.84	0.00e+00	3382.00
IUUC-Cja-019191	Callithrix jacchus	98.89	0.00e+00	3411.00
IUUC-Cfa-020041	Canis familiaris	97.92	0.00e+00	3112.00
IUUC-Csa-023689	Chlorocebus sabaeus	98.90	0.00e+00	3411.00
IUUC-Cho-025038	Choloepus hoffmanni	96.87	0.00e+00	1491.00
IUUC-Dno-029982	Dasypus novemcinctus	95.37	0.00e+00	3296.00
IUUC-Eca-034161	Equus caballus	97.50	0.00e+00	3379.00
IUUC-Fca-036307	Felis catus	97.90	0.00e+00	3383.00
IUUC-Fal-037332	Ficedula albicollis	91.37	0.00e+00	3183.00
IUUC-Ggo-045107	Gorilla gorilla	99.30	0.00e+00	3417.00
IUUC-Hsa-046482	Homo sapiens	99.18	0.00e+00	3414.00
IUUC-Itr-049023	Ictidomys tridecemlineatus	95.83	0.00e+00	3362.00
IUUC-Lch-050345	Latimeria chalumnae	88.02	0.00e+00	2608.00
IUUC-Loc-052642	Lepisosteus oculatus	88.15	0.00e+00	3043.00
IUUC-Laf-053649	Loxodonta africana	96.79	0.00e+00	3301.00
IUUC-Mga-059202	Meleagris gallopavo	92.90	0.00e+00	3226.00
IUUC-Mmr-060729	Microcebus murinus	97.97	0.00e+00	3381.00
IUUC-Mdo-062462	Monodelphis domestica	95.34	0.00e+00	3312.00
IUUC-Mmu-063865	Mus musculus	96.79	0.00e+00	3370.00
IUUC-Mpu-066724	Mustela putorius furo	98.14	0.00e+00	3390.00
IUUC-Mlu-067816	Myotis lucifugus	97.45	0.00e+00	3379.00
IUUC-Opr-070213	Ochotona princeps	94.12	0.00e+00	1641.00
IUUC-Oan-073563	Ornithorhynchus anatinus	95.12	0.00e+00	3296.00
IUUC-Ocu-074531	Oryctolagus cuniculus	98.02	0.00e+00	3388.00
IUUC-Olu-087860	Ostreococcus lucimarinus	39.01	2.00e-117	416.00
IUUC-Oga-088665	Otolemur garnettii	97.33	0.00e+00	3357.00
IUUC-Oar-090429	Ovis aries	98.02	0.00e+00	3390.00
IUUC-Ptr-091168	Pan troglodytes	88.38	0.00e+00	2980.00
IUUC-Pan-092788	Papio anubis	99.94	0.00e+00	3114.00
IUUC-Psi-093281	Pelodiscus sinensis	92.00	0.00e+00	3162.00
IUUC-Pma-094424	Petromyzon marinus	72.83	7.00e-125	439.00
IUUC-Pab-098561	Pongo abelii	97.81	0.00e+00	2892.00
IUUC-Pca-100177	Procavia capensis	85.86	0.00e+00	1535.00
IUUC-Rno-105002	Rattus norvegicus	95.92	0.00e+00	3358.00
IUUC-Sha-107105	Sarcophilus harrisii	92.44	0.00e+00	3192.00
IUUC-Ssc-116282	Sus scrofa	98.14	0.00e+00	3389.00
IUUC-Tgu-116807	Taeniopygia guttata	93.65	0.00e+00	3229.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence