iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tni-120118

UUCD1 version

UUC-TeN-00444

Ensembl Protein ID

ENSTNIP00000009222.1

UniProt Accession

H3CLU3; H3CLU3_TETNG

Protein Name

Uncharacterized protein

Gene Name

EML6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTNIG00000006454.1	ENSTNIT00000009393.1	ENSTNIP00000009222.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.40e-51	170.4	1686	1718
UBD/Beta-Prp	5.70e-123	410.1	725	941

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 4    dsvtclaf.sd.tllvsGsdDgtikvWDlrtgv 34
           +++++la  ++ +  vs+sdDgt+++WDl + +
   Q: 1686 GGIWGLAAhPSkDVCVSASDDGTVRIWDLADKK 1718
           458888878777999*************98765 PP

UBD/Beta-Prp

   S: 7    ghhksvitcvkfspdksllatg..srdgtikvwdvttgkllrsl.sgheaevtavkfspdgkilvtgseD..rtikvwdlstgkcvhtl 90
           gh+++v++ ++++p k+++a++  +rd+ i vwdv+t k+l+ l   h+++v++++f  dgk lv+++ D  + i +wd ++g+ + + 
   Q: 725  GHDDDVLS-LTVHPLKDVVASAqvGRDAAIHVWDVQTLKCLSLLkGHHSQGVSSLEFTADGKSLVSVGIDqfHSILIWDWKKGERLAKA 812
           78899998.999*******9974479******************5557899*******************9999*************** PP
   S: 91   kghedsvlslsfsp.sgdklvsGshdrtirvwdletgqclee....tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrt 174
           +gh+d++  ++ +p  +dklv+ +  + i+ w+++ g    +     + g++++ +++++  +++l++sG++++ + +W  +  +l++t
   Q: 813  RGHKDKIFVVRTNPfRTDKLVTVG-IKHIKFWQHSGGGLTFKrgifGNLGKQETMMSACFGRSEDLVFSGATNGDIYIW--RDTTLIKT 898
           **************8889999988.99*****9999888777899888899999********99***************..88****** PP
   S: 175  ltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlng 220
            +  h+++v  +   +  k +v+g++dg v+lwd   ++c++t+  
   Q: 899  IKA-HDGPVFAMCSLD--KGFVTGGKDGVVELWDDMFERCLKTYAI 941
           *98.*****9999888..57*********************99965 PP

Organism

Tetraodon nigroviridis

Protein Sequence
(Fasta)

MSDKTAPRCQ LRLEWIHGYR GHQCRNNLYY TAGKEVVYFV AGVGVVYNTR DHTQKFYLGH 60
NDDIISLAIH PDKVQVATGQ VGKDPFICIW DTYSMQTVSI LRDVHTHGVA CLAFDAEGQR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGCGATA AGACGGCGCC GCGCTGCCAG CTGAGGCTGG AGTGGATCCA CGGCTACCGA 60
GGCCACCAGT GCCGGAACAA CCTGTACTAC ACGGCAGGAA AAGAGGTGGT GTACTTCGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR005108--HELP
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001387	Ailuropoda melanoleuca	76.45	0.00e+00	3090.00
IUUC-Apl-003604	Anas platyrhynchos	76.04	0.00e+00	3061.00
IUUC-Aca-004572	Anolis carolinensis	73.89	0.00e+00	3005.00
IUUC-Ame-010713	Astyanax mexicanus	81.70	0.00e+00	3291.00
IUUC-Bta-012812	Bos taurus	76.35	0.00e+00	3084.00
IUUC-Cja-019191	Callithrix jacchus	75.87	0.00e+00	3052.00
IUUC-Cfa-020041	Canis familiaris	76.42	0.00e+00	2869.00
IUUC-Csa-023689	Chlorocebus sabaeus	75.51	0.00e+00	2977.00
IUUC-Cho-025038	Choloepus hoffmanni	74.68	0.00e+00	1161.00
IUUC-Cin-025205	Ciona intestinalis	59.11	0.00e+00	2410.00
IUUC-Csv-026014	Ciona savignyi	59.40	0.00e+00	2412.00
IUUC-Dno-029982	Dasypus novemcinctus	74.86	0.00e+00	2942.00
IUUC-Eca-034161	Equus caballus	74.53	0.00e+00	2923.00
IUUC-Fca-036307	Felis catus	76.75	0.00e+00	3103.00
IUUC-Fal-037332	Ficedula albicollis	75.77	0.00e+00	3024.00
IUUC-Gmo-039057	Gadus morhua	79.33	0.00e+00	3153.00
IUUC-Gac-042555	Gasterosteus aculeatus	88.10	0.00e+00	3496.00
IUUC-Ggo-045107	Gorilla gorilla	76.55	0.00e+00	3094.00
IUUC-Hsa-046482	Homo sapiens	76.55	0.00e+00	3095.00
IUUC-Itr-049023	Ictidomys tridecemlineatus	74.57	0.00e+00	2978.00
IUUC-Loc-052642	Lepisosteus oculatus	79.79	0.00e+00	3186.00
IUUC-Laf-053649	Loxodonta africana	74.80	0.00e+00	3000.00
IUUC-Meu-056618	Macropus eugenii	64.81	0.00e+00	1510.00
IUUC-Mga-059202	Meleagris gallopavo	75.23	0.00e+00	2955.00
IUUC-Mmr-060729	Microcebus murinus	74.80	0.00e+00	3065.00
IUUC-Mdo-062462	Monodelphis domestica	75.72	0.00e+00	2989.00
IUUC-Mmu-063865	Mus musculus	76.14	0.00e+00	3107.00
IUUC-Mpu-066724	Mustela putorius furo	76.55	0.00e+00	3097.00
IUUC-Mlu-067816	Myotis lucifugus	76.08	0.00e+00	3083.00
IUUC-Opr-070213	Ochotona princeps	74.15	0.00e+00	1623.00
IUUC-Ont-071928	Oreochromis niloticus	75.11	0.00e+00	3043.00
IUUC-Oan-073563	Ornithorhynchus anatinus	76.66	0.00e+00	3093.00
IUUC-Ocu-074531	Oryctolagus cuniculus	76.40	0.00e+00	3095.00
IUUC-Ola-086943	Oryzias latipes	73.86	0.00e+00	2935.00
IUUC-Oga-088665	Otolemur garnettii	75.20	0.00e+00	2949.00
IUUC-Oar-090429	Ovis aries	76.50	0.00e+00	3094.00
IUUC-Psi-093281	Pelodiscus sinensis	75.42	0.00e+00	3039.00
IUUC-Pma-094424	Petromyzon marinus	69.20	8.00e-118	416.00
IUUC-Pfo-096150	Poecilia formosa	86.07	0.00e+00	3326.00
IUUC-Rno-105002	Rattus norvegicus	76.14	0.00e+00	3101.00
IUUC-Sha-107105	Sarcophilus harrisii	73.73	0.00e+00	2887.00
IUUC-Ssc-116282	Sus scrofa	76.14	0.00e+00	2996.00
IUUC-Tgu-116807	Taeniopygia guttata	76.09	0.00e+00	3061.00
IUUC-Tru-118040	Takifugu rubripes	91.12	0.00e+00	3544.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence