iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tgu-117076

Ensembl Protein ID

ENSTGUP00000003574.1

UniProt Accession

H0YZ41; H0YZ41_TAEGU

Genbank Protein ID

ENSTGUP00000003574

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABQF01034401

Gene Name

KIF21A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTGUG00000003457.1	ENSTGUT00000003611.1	ENSTGUP00000003574.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.20e-30	101.8	1293	1327
UBD/Beta-Prp	1.60e-43	148.8	1348	1603

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsdtllvsGsdDgtikvWDlrtgvl 35
           gHt  v c++ +d+ll +Gs D t+kvW+l tg  
   Q: 1293 GHTKAVLCVDATDDLLFTGSKDRTCKVWNLVTGQE 1327
           8********9878*****************99976 PP

UBD/Beta-Prp

   S: 23   sllatgsrdgtikvwdvttgkl.lrsl.sgheae.....................vtavkfspdgkilvtgseDrtikvwdlstgkc 86
           sl++t s ++ ikvwd+++  + +r+l s+ +a                      ++++ ++p+g +++ ++  + ++ wdl+ ++ 
   Q: 1348 SLVFTVS-TSYIKVWDIRDSAKcIRTLtSSGQAMpadvcsgstnrtvaipagenqINQIALNPTG-TFLYAAAGNSVRMWDLKRFQS 1432
           5677777.99*******98754499995555555999***************************9.9******************** PP
   S: 87   vhtlkghedsvlslsfsp..sg.dklvsGshdrtirvwdletgqclee.....tlsghdgvvncvvvhpdgnllvsGslDrtvrlWd 165
           + +l+gh+  v++l++++  +g d +++Gs+d +i+++d+ +g   +      ++ +h + +  +++++  + l+sGs D+ ++ Wd
   Q: 1433 TGKLTGHQGPVMCLTVDQisNGqDLIITGSKDHYIKMFDVTEGALGSVspthnFEPPHYDGIEALAIMG--DNLFSGSRDNGIKKWD 1517
           *******************9888*******************987766777889999************..6799************ PP
   S: 166  lktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriW... 249
           l++++ll++   +h+d v  l + +  + l+sg + gt+klw++ t   + +++gh+++++ + +   +  + ++++D+++riW   
   Q: 1518 LSQKDLLQQVPNAHKDWVCALGLVPGVPVLLSGCRGGTLKLWNVDTFAPIGEMKGHDSPINAICTN--SSQIFTAADDRTVRIWkar 1602
           **********999************************************************87777..****************555 PP
   S: 250  d 250
           +
   Q: 1603 N 1603
           4 PP

Organism

Taeniopygia guttata

Protein Sequence
(Fasta)

MSAGLDESSV RVAVRIRPQL AKEKIEGCHI CTSVTPGEPQ VFLGKDKAFT FDYVFNIDSQ 60
QEEIYVQCIE KLIEGCFEGY NATVFAYGQT GAGKTYTMGT GFDVNITEEE QGIISRAVKH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCGGCCG GCCTGGACGA GAGCTCGGTG CGGGTCGCGG TCAGGTAAGC GGCGGCTGCT 60
GCGGGCCGGT GCGGGCGGCG GGGCCGCGGC GTGTTCCCAG CGCCCACCCG GCCGGGACGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0505--Motor protein
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR019821--Kinesin_motor_CS
IPR001752--Kinesin_motor_dom
IPR027417--P-loop_NTPase
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00411--KINESIN_MOTOR_1
PS50067--KINESIN_MOTOR_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00225--Kinesin
PF00400--WD40

PRINTS

PR00380--KINESINHEAVY

SMART

SM00129--KISc
SM00320--WD40

Gene Ontology

GO:0005524--F:ATP binding
GO:0003777--F:microtubule motor activity
GO:0007018--P:microtubule-based movement

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001391	Ailuropoda melanoleuca	82.89	0.00e+00	2605.00
IUUC-Apl-003353	Anas platyrhynchos	88.70	0.00e+00	2718.00
IUUC-Aca-004467	Anolis carolinensis	85.79	0.00e+00	2667.00
IUUC-Ame-011430	Astyanax mexicanus	64.20	0.00e+00	1216.00
IUUC-Bta-013485	Bos taurus	81.94	0.00e+00	2523.00
IUUC-Cel-018402	Caenorhabditis elegans	54.37	9.00e-146	511.00
IUUC-Cja-019385	Callithrix jacchus	81.09	0.00e+00	2514.00
IUUC-Cfa-020986	Canis familiaris	82.46	0.00e+00	2548.00
IUUC-Cpo-022297	Cavia porcellus	79.13	0.00e+00	1523.00
IUUC-Csa-023685	Chlorocebus sabaeus	82.08	0.00e+00	2570.00
IUUC-Cho-024531	Choloepus hoffmanni	81.74	0.00e+00	909.00
IUUC-Cin-025160	Ciona intestinalis	38.14	1.00e-85	310.00
IUUC-Dre-028532	Danio rerio	63.19	0.00e+00	1221.00
IUUC-Dno-029972	Dasypus novemcinctus	79.41	0.00e+00	2424.00
IUUC-Ete-032872	Echinops telfairi	68.97	0.00e+00	904.00
IUUC-Eca-033518	Equus caballus	82.11	0.00e+00	2565.00
IUUC-Fca-036197	Felis catus	82.33	0.00e+00	2558.00
IUUC-Fal-037534	Ficedula albicollis	95.96	0.00e+00	2873.00
IUUC-Gga-040687	Gallus gallus	89.90	0.00e+00	2700.00
IUUC-Gac-041626	Gasterosteus aculeatus	66.25	0.00e+00	2039.00
IUUC-Ggo-044457	Gorilla gorilla	82.55	0.00e+00	2551.00
IUUC-Hsa-046372	Homo sapiens	82.72	0.00e+00	2569.00
IUUC-Itr-049068	Ictidomys tridecemlineatus	51.58	0.00e+00	850.00
IUUC-Lch-049786	Latimeria chalumnae	53.91	0.00e+00	1006.00
IUUC-Loc-052689	Lepisosteus oculatus	72.61	0.00e+00	2239.00
IUUC-Laf-054018	Loxodonta africana	78.95	0.00e+00	2387.00
IUUC-Mcc-055558	Macaca mulatta	82.90	0.00e+00	2582.00
IUUC-Meu-056080	Macropus eugenii	83.55	0.00e+00	888.00
IUUC-Mga-059283	Meleagris gallopavo	89.22	0.00e+00	2641.00
IUUC-Mmr-060773	Microcebus murinus	81.41	0.00e+00	2481.00
IUUC-Mdo-062688	Monodelphis domestica	81.02	0.00e+00	2299.00
IUUC-Mmu-063997	Mus musculus	80.10	0.00e+00	1541.00
IUUC-Mpu-066354	Mustela putorius furo	83.61	0.00e+00	2570.00
IUUC-Mlu-067599	Myotis lucifugus	81.82	0.00e+00	2524.00
IUUC-Nle-069477	Nomascus leucogenys	82.84	0.00e+00	2575.00
IUUC-Opr-070188	Ochotona princeps	79.90	0.00e+00	1229.00
IUUC-Ont-071938	Oreochromis niloticus	67.42	0.00e+00	2045.00
IUUC-Oan-073055	Ornithorhynchus anatinus	80.75	0.00e+00	2375.00
IUUC-Ocu-074302	Oryctolagus cuniculus	80.11	0.00e+00	2523.00
IUUC-Ola-086604	Oryzias latipes	65.24	0.00e+00	1968.00
IUUC-Oga-088799	Otolemur garnettii	80.96	0.00e+00	2257.00
IUUC-Oar-089629	Ovis aries	82.65	0.00e+00	2516.00
IUUC-Ptr-090535	Pan troglodytes	54.24	0.00e+00	972.00
IUUC-Pan-092214	Papio anubis	83.91	0.00e+00	2578.00
IUUC-Psi-093757	Pelodiscus sinensis	84.20	0.00e+00	2468.00
IUUC-Pfo-097448	Poecilia formosa	63.12	0.00e+00	1826.00
IUUC-Pab-097984	Pongo abelii	82.78	0.00e+00	2561.00
IUUC-Pca-101061	Procavia capensis	70.45	0.00e+00	1184.00
IUUC-Pva-102306	Pteropus vampyrus	82.75	0.00e+00	2484.00
IUUC-Rno-105354	Rattus norvegicus	80.48	0.00e+00	1534.00
IUUC-Sha-106938	Sarcophilus harrisii	80.17	0.00e+00	1590.00
IUUC-Ssc-115810	Sus scrofa	81.62	0.00e+00	2514.00
IUUC-Tru-118091	Takifugu rubripes	62.01	0.00e+00	1176.00
IUUC-Tsy-119020	Tarsius syrichta	82.97	0.00e+00	2541.00
IUUC-Tni-120813	Tetraodon nigroviridis	61.83	0.00e+00	1158.00
IUUC-Tbe-127494	Tupaia belangeri	70.48	0.00e+00	837.00
IUUC-Ttr-128393	Tursiops truncatus	77.86	0.00e+00	2322.00
IUUC-Vpa-130675	Vicugna pacos	92.13	0.00e+00	664.00
IUUC-Xtr-132829	Xenopus tropicalis	76.38	0.00e+00	2404.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence