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Tag Content
UUCD2 ID IUUC-Cpo-022182
UUCD1 version UUC-CaP-00198
Ensembl Protein ID ENSCPOP00000003899.2
UniProt Accession H0V2W5; H0V2W5_CAVPO
Genbank Protein ID ENSCPOP00000003899
Protein Name Uncharacterized protein
Genbank Nucleotide ID AAKN02014519
Gene Name MDM2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSCPOG00000004323.3 ENSCPOT00000004369.2 ENSCPOP00000003899.2
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 activity/RING/RING 89.63 0.00e+00 750.00 IUUC-Hsa-046376
E3 activity/RING/RING 78.63 0.00e+00 630.00 IUUC-Mmu-063207
E3 activity/RING/RING 79.59 0.00e+00 658.00 IUUC-Rno-105641
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Cavia porcellus
Protein Sequence
(Fasta)
RPMCNTNMSV STDGAVSTSQ IPASEQETLV RPKPLLLKLL KSVGAQKDTY TMKEVIFYLG 60
QYIMTKRLYD EKQQHIVYCS NDLLGDLFGV PSFSVKEHRK IYTMIYRNLI VVNQQEPLDS 120
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Protein Fasta Sequence



>IUUC-Cpo-022182|E3,RING|Cavia porcellus
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Nucleotide Sequence
(Fasta)
AGGCCAATGT GCAATACCAA CATGTCTGTG TCTACTGATG GTGCTGTAAG CACCTCACAG 60
ATTCCTGCTT CGGAACAAGA GACCCTGGTT GGTATTTTTG TCTCAAGTGT AATGTTAGAA 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Cpo-022182|E3,RING|Cavia porcellus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome

Interpro

IPR028340--Mdm2
IPR015459--MDM2_E3_ligase
IPR016495--p53_neg-reg_MDM_2/4
IPR003121--SWIB_MDM2_domain
IPR001876--Znf_RanBP2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2
PS50089--ZF_RING_2

Pfam

PF02201--SWIB
PF00641--zf-RanBP

Gene Ontology

GO:0005737--C:cytoplasm
GO:0016604--C:nuclear body
GO:0005730--C:nucleolus
GO:0043234--C:protein complex
GO:0016874--F:ligase activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0003283--P:atrial septum development
GO:0003181--P:atrioventricular valve morphogenesis
GO:0001568--P:blood vessel development
GO:0001974--P:blood vessel remodeling
GO:0060411--P:cardiac septum morphogenesis
GO:0071456--P:cellular response to hypoxia
GO:0006977--P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0003203--P:endocardial cushion morphogenesis
GO:0045184--P:establishment of protein localization
GO:0043066--P:negative regulation of apoptotic process
GO:0071157--P:negative regulation of cell cycle arrest
GO:0043518--P:negative regulation of DNA damage response, signal transduction by p53 class mediator
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0018205--P:peptidyl-lysine modification
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0051865--P:protein autoubiquitination
GO:0006461--P:protein complex assembly
GO:0031648--P:protein destabilization
GO:0034504--P:protein localization to nucleus
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0002027--P:regulation of heart rate
GO:0046677--P:response to antibiotic
GO:0007089--P:traversing start control point of mitotic cell cycle
GO:0003281--P:ventricular septum development

Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002039 Ailuropoda melanoleuca 88.62 0.00e+00 766.00
IUUC-Apl-003193 Anas platyrhynchos 63.41 2.00e-150 525.00
IUUC-Aca-004305 Anolis carolinensis 57.58 3.00e-112 399.00
IUUC-Ame-010675 Astyanax mexicanus 46.02 4.00e-87 315.00
IUUC-Bta-013270 Bos taurus 88.59 0.00e+00 731.00
IUUC-Cja-019744 Callithrix jacchus 87.80 0.00e+00 740.00
IUUC-Cfa-020807 Canis familiaris 86.97 0.00e+00 707.00
IUUC-Cre-022828 Chlamydomonas reinhardtii 35.42 7.00e-06 41.60
IUUC-Csa-023541 Chlorocebus sabaeus 89.80 0.00e+00 763.00
IUUC-Cho-024831 Choloepus hoffmanni 70.59 2.00e-82 298.00
IUUC-Cin-025448 Ciona intestinalis 28.77 1.00e-21 95.90
IUUC-Csv-026151 Ciona savignyi 30.14 1.00e-10 60.50
IUUC-Dre-028419 Danio rerio 43.28 5.00e-52 198.00
IUUC-Dno-028950 Dasypus novemcinctus 87.96 0.00e+00 769.00
IUUC-Dor-031048 Dipodomys ordii 72.47 1.00e-173 602.00
IUUC-Ete-032264 Echinops telfairi 66.94 9.00e-168 583.00
IUUC-Eca-033301 Equus caballus 79.27 0.00e+00 677.00
IUUC-Eeu-035005 Erinaceus europaeus 77.76 5.00e-175 607.00
IUUC-Fca-035454 Felis catus 89.18 0.00e+00 760.00
IUUC-Fal-036720 Ficedula albicollis 60.13 6.00e-70 257.00
IUUC-Gmo-039296 Gadus morhua 43.12 2.00e-46 179.00
IUUC-Gga-040251 Gallus gallus 64.77 2.00e-145 508.00
IUUC-Gac-041528 Gasterosteus aculeatus 42.05 1.00e-35 144.00
IUUC-Ggo-044948 Gorilla gorilla 82.24 0.00e+00 697.00
IUUC-Hsa-046376 Homo sapiens 89.63 0.00e+00 767.00
IUUC-Itr-048328 Ictidomys tridecemlineatus 89.27 0.00e+00 733.00
IUUC-Lch-050037 Latimeria chalumnae 55.80 2.00e-114 405.00
IUUC-Loc-051837 Lepisosteus oculatus 49.80 5.00e-110 391.00
IUUC-Laf-053483 Loxodonta africana 82.11 0.00e+00 715.00
IUUC-Mcc-055294 Macaca mulatta 89.84 0.00e+00 769.00
IUUC-Mga-060007 Meleagris gallopavo 63.64 2.00e-139 488.00
IUUC-Mmr-060673 Microcebus murinus 87.96 0.00e+00 758.00
IUUC-Mdo-063057 Monodelphis domestica 71.54 3.00e-180 624.00
IUUC-Mmu-063207 Mus musculus 80.44 0.00e+00 627.00
IUUC-Mpu-065836 Mustela putorius furo 86.94 0.00e+00 757.00
IUUC-Mlu-068193 Myotis lucifugus 84.04 0.00e+00 740.00
IUUC-Nle-069927 Nomascus leucogenys 89.63 0.00e+00 767.00
IUUC-Opr-070590 Ochotona princeps 82.04 0.00e+00 674.00
IUUC-Ont-071984 Oreochromis niloticus 42.58 2.00e-52 199.00
IUUC-Oan-072744 Ornithorhynchus anatinus 69.46 2.00e-156 545.00
IUUC-Ocu-074071 Oryctolagus cuniculus 89.47 0.00e+00 755.00
IUUC-Ola-087329 Oryzias latipes 41.38 4.00e-74 271.00
IUUC-Oga-088135 Otolemur garnettii 80.16 0.00e+00 697.00
IUUC-Oar-090078 Ovis aries 88.16 0.00e+00 762.00
IUUC-Ptr-091399 Pan troglodytes 89.63 0.00e+00 768.00
IUUC-Pan-092720 Papio anubis 89.84 0.00e+00 769.00
IUUC-Psi-093591 Pelodiscus sinensis 65.21 4.00e-125 441.00
IUUC-Pma-094500 Petromyzon marinus 62.50 4.00e-19 87.80
IUUC-Pfo-096316 Poecilia formosa 41.41 2.00e-73 269.00
IUUC-Pab-097696 Pongo abelii 89.23 0.00e+00 758.00
IUUC-Pca-100974 Procavia capensis 80.16 0.00e+00 725.00
IUUC-Pva-102488 Pteropus vampyrus 82.89 0.00e+00 677.00
IUUC-Rno-105641 Rattus norvegicus 81.43 0.00e+00 649.00
IUUC-Sha-107314 Sarcophilus harrisii 70.02 0.00e+00 634.00
IUUC-Sar-112938 Sorex araneus 81.63 0.00e+00 701.00
IUUC-Ssc-115495 Sus scrofa 87.96 0.00e+00 738.00
IUUC-Tgu-116623 Taeniopygia guttata 63.56 3.00e-145 508.00
IUUC-Tru-117820 Takifugu rubripes 39.09 5.00e-71 261.00
IUUC-Tsy-119162 Tarsius syrichta 62.13 5.00e-77 281.00
IUUC-Tni-119793 Tetraodon nigroviridis 43.14 1.00e-46 180.00
IUUC-Tbe-127816 Tupaia belangeri 69.25 2.00e-112 399.00
IUUC-Ttr-129194 Tursiops truncatus 77.75 2.00e-175 608.00
IUUC-Vpa-130326 Vicugna pacos 82.32 0.00e+00 670.00
IUUC-Xtr-132216 Xenopus tropicalis 54.46 3.00e-110 392.00
Created Date 25-Jun-2017

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