iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSONIG00000001037.1	ENSONIT00000001312.1	ENSONIP00000001313.1
ENSONIG00000001037.1	ENSONIT00000001313.1	ENSONIP00000001314.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.40e-32	109.1	181	218
UBD/Beta-Prp	1.60e-49	169.1	280	511

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gH +sv+c+ f  + +++ +GsdD+ +k+W +++g+ll
   Q: 181  GHLSSVYCVTFdRTgRRIFTGSDDCLVKIWGTDDGRLL 218
           8**********955599*****************9987 PP

UBD/Beta-Prp

   S: 19   spdksllatgsrdgtikvwdvttgkl......lrslsgheae...vtavkfspdgkilvtgseDrtikvw..dlstgkcvhtlkgheds 96
           s +k++l ++++dgti  w+++  +l       + +s+++ +     + +fs  g +l+tgs+D++i+v+     +++ ++ l+ h+d+
   Q: 280  SGSKRYLSSTGADGTICFWQWDARTLkfgkpnSANMSKCSRPgvqMICSSFSAGGMFLATGSTDHIIRVYyfGSGQPEKISELESHTDK 368
           67899******************999999999777766654444456777899999**************665669999********** PP
   S: 97   vlslsfsp.sgdklvsGshdrtirvwdletgqclee.................tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlk 167
           v s++fs  s+ ++vsGs+d t+r+w+l+ + + +                   +++++  v++v+++  ++ +++++++ t+++W++ 
   Q: 369  VDSIQFSHcSDRWFVSGSRDGTARIWQLHPQGWKSIlldmqtklpgkynppplEDKVTKLKVTMVAWDRHDSTVITAANNLTLKVWNSI 457
           ********899******************99999889***************889999999**************************** PP
   S: 168  tgkllrtltgghtdsvysls...fdsngkelvsgsldgtvklwdlqtgecvrtlngh 221
           tg+l++ l g h+d v  l+   fd+  + l s+++dg  ++wdl +g  +r++ + 
   Q: 458  TGNLVHVLMG-HEDEVFVLEphpFDP--RILFSAGHDGNCIVWDLARGVKIRSYFNM 511
           *********9.*********999999..99****************99998877653 PP

Organism

Oreochromis niloticus

Protein Sequence
(Fasta)

MASDSTHIAQ LTSELYFLIA RFLEAGPCQK AAETLIREVE EKELLPRRLD WTGQEHPGTY 60
ENLVKLYRHI TPDHLLQVCT RVCPLLEREV PASVPGLTSL LGAGRQNLLR TAKSCKHVVW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGGGGGAGG GGGATTAAAA CAAACATGCC TCCACGGAAA ACCGGTCGTA AGTGAAATTC 60
GCCCCAGCCG GCGCTCAGTA CAGCCACAAT TTAGCTATTC GGTCTTTGTT AAAGGAAGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0103--Bromodomain
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR002469--Peptidase_S9B_N
IPR028738--PHIP
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00439--Bromodomain
PF00400--WD40

PRINTS

PR00503--BROMODOMAIN

SMART

SM00297--BROMO
SM00320--WD40

Gene Ontology

GO:0008286--P:insulin receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001113	Aegilops tauschii	32.41	2.00e-60	228.00
IUUC-Aml-002299	Ailuropoda melanoleuca	76.32	0.00e+00	1248.00
IUUC-Atr-002600	Amborella trichopoda	32.76	6.00e-72	266.00
IUUC-Apl-003700	Anas platyrhynchos	73.41	0.00e+00	1986.00
IUUC-Aly-006517	Arabidopsis lyrata	28.85	6.00e-74	273.00
IUUC-Ath-006801	Arabidopsis thaliana	32.63	2.00e-69	258.00
IUUC-Bta-013125	Bos taurus	76.32	0.00e+00	1221.00
IUUC-Bdi-014797	Brachypodium distachyon	31.63	2.00e-58	221.00
IUUC-Bol-015737	Brassica oleracea	31.94	5.00e-73	270.00
IUUC-Bra-017961	Brassica rapa	31.99	3.00e-72	268.00
IUUC-Cja-018868	Callithrix jacchus	72.17	0.00e+00	2084.00
IUUC-Cfa-021179	Canis familiaris	74.06	0.00e+00	1263.00
IUUC-Cpo-022077	Cavia porcellus	70.22	0.00e+00	1899.00
IUUC-Cre-023003	Chlamydomonas reinhardtii	33.94	5.00e-34	140.00
IUUC-Csa-023618	Chlorocebus sabaeus	76.22	0.00e+00	1330.00
IUUC-Cho-024794	Choloepus hoffmanni	73.62	0.00e+00	697.00
IUUC-Dre-028029	Danio rerio	81.33	0.00e+00	1392.00
IUUC-Dno-030048	Dasypus novemcinctus	73.64	0.00e+00	1264.00
IUUC-Dme-031752	Drosophila melanogaster	52.17	0.00e+00	651.00
IUUC-Eca-034274	Equus caballus	76.20	0.00e+00	1208.00
IUUC-Eeu-034688	Erinaceus europaeus	78.62	0.00e+00	1083.00
IUUC-Fca-035451	Felis catus	76.38	0.00e+00	1234.00
IUUC-Fal-037465	Ficedula albicollis	72.51	0.00e+00	2004.00
IUUC-Gmo-039451	Gadus morhua	78.75	0.00e+00	814.00
IUUC-Gga-040798	Gallus gallus	73.35	0.00e+00	2067.00
IUUC-Gma-043340	Glycine max	32.13	3.00e-70	261.00
IUUC-Ggo-045347	Gorilla gorilla	76.20	0.00e+00	1256.00
IUUC-Hsa-046757	Homo sapiens	75.40	0.00e+00	1313.00
IUUC-Hvu-047706	Hordeum vulgare	32.30	3.00e-38	152.00
IUUC-Loc-052672	Lepisosteus oculatus	72.08	0.00e+00	2264.00
IUUC-Laf-054140	Loxodonta africana	76.23	0.00e+00	1234.00
IUUC-Mcc-055061	Macaca mulatta	75.54	0.00e+00	1316.00
IUUC-Mtr-058094	Medicago truncatula	32.51	8.00e-70	259.00
IUUC-Mmr-060837	Microcebus murinus	74.37	0.00e+00	1258.00
IUUC-Mdo-061903	Monodelphis domestica	75.40	0.00e+00	1330.00
IUUC-Mmu-063772	Mus musculus	75.43	0.00e+00	1311.00
IUUC-Mac-065343	Musa acuminata	31.73	9.00e-74	273.00
IUUC-Mlu-067928	Myotis lucifugus	75.65	0.00e+00	1243.00
IUUC-Nle-070094	Nomascus leucogenys	76.24	0.00e+00	1271.00
IUUC-Opr-070971	Ochotona princeps	57.14	0.00e+00	674.00
IUUC-Ocu-074033	Oryctolagus cuniculus	76.07	0.00e+00	1216.00
IUUC-Oin-079669	Oryza indica	32.98	8.00e-53	202.00
IUUC-Olo-080755	Oryza longistaminata	32.77	2.00e-53	204.00
IUUC-Ola-086648	Oryzias latipes	91.18	0.00e+00	1576.00
IUUC-Olu-087745	Ostreococcus lucimarinus	26.36	2.00e-53	204.00
IUUC-Oga-088578	Otolemur garnettii	76.07	0.00e+00	1217.00
IUUC-Oar-090247	Ovis aries	76.32	0.00e+00	1219.00
IUUC-Ptr-091266	Pan troglodytes	76.05	0.00e+00	1237.00
IUUC-Pan-092734	Papio anubis	76.22	0.00e+00	1330.00
IUUC-Pma-094427	Petromyzon marinus	61.45	4.00e-119	421.00
IUUC-Ppa-095793	Physcomitrella patens	30.50	1.00e-71	266.00
IUUC-Pfo-096191	Poecilia formosa	86.01	0.00e+00	2801.00
IUUC-Pab-098402	Pongo abelii	75.74	0.00e+00	1312.00
IUUC-Pop-099803	Populus trichocarpa	34.09	2.00e-76	281.00
IUUC-Pca-101128	Procavia capensis	79.92	0.00e+00	1191.00
IUUC-Ppe-101849	Prunus persica	31.48	9.00e-73	269.00
IUUC-Pva-103058	Pteropus vampyrus	78.35	0.00e+00	1142.00
IUUC-Rno-106013	Rattus norvegicus	74.39	0.00e+00	1196.00
IUUC-Sha-107496	Sarcophilus harrisii	75.60	0.00e+00	1271.00
IUUC-Sit-110017	Setaria italica	32.67	4.00e-55	211.00
IUUC-Sly-111348	Solanum lycopersicum	32.18	8.00e-73	269.00
IUUC-Sbi-114195	Sorghum bicolor	30.82	1.00e-56	214.00
IUUC-Ssc-115461	Sus scrofa	69.02	0.00e+00	1158.00
IUUC-Tru-117625	Takifugu rubripes	84.26	0.00e+00	2781.00
IUUC-Tsy-119132	Tarsius syrichta	70.03	0.00e+00	1006.00
IUUC-Tni-120716	Tetraodon nigroviridis	83.33	0.00e+00	2791.00
IUUC-Tca-121615	Theobroma cacao	31.84	7.00e-70	259.00
IUUC-Tae-125478	Triticum aestivum	31.70	2.00e-71	265.00
IUUC-Tur-126809	Triticum urartu	31.67	4.00e-69	258.00
IUUC-Tbe-127479	Tupaia belangeri	66.93	0.00e+00	979.00
IUUC-Ttr-128427	Tursiops truncatus	67.80	0.00e+00	1154.00
IUUC-Vvi-131332	Vitis vinifera	33.38	1.00e-78	288.00
IUUC-Xtr-132717	Xenopus tropicalis	71.48	0.00e+00	2058.00
IUUC-Xma-134120	Xiphophorus maculatus	92.98	0.00e+00	1549.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence