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Tag Content
iUUCD ID IUUC-Oga-088468
Ensembl Protein ID ENSOGAP00000004281.2
UniProt Accession H0WQP0; H0WQP0_OTOGA
Genbank Protein ID ENSOGAP00000004281
Protein Name Autophagy protein 5
Genbank Nucleotide ID AAQR03003229
Gene Name ATG5
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSOGAG00000004787.2 ENSOGAT00000004789.2 ENSOGAP00000004281.2
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 adaptor/Cullin RING/Other 24.16 7.00e-11 62.40 IUUC-Sce-106216
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Otolemur garnettii
Functional Description
(View)

Functional Description



     Involved in autophagic vesicle formation.
Involved in autophagic vesicle formation.
Protein Sequence
(Fasta)
MTDDKDVLRD VWFGRIPTCF TLYQDEITER EAEPYYLLLP RVSYLTLVTD KVKKHFQKVM 60
RQEDVSEIWF EYEGTPLKWH YPIGLLFDLL ASSSPLPWNI TVHFKSFPEK DLLHCPSKDV 120
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Protein Fasta Sequence



>IUUC-Oga-088468|E3,Cullin RING/Other|Otolemur garnettii
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GTTTGGCTTT GGTTGAAAAG AATTTGGCCT GCATGTACTG TCTTAACCAC TGGAAGAATG 60
ACAGATGACA AAGATGTGCT TCGAGATGTG TGGTTTGGAC GAATTCCAAC TTGCTTCACT 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Oga-088468|E3,Cullin RING/Other|Otolemur garnettii
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0072--Autophagy
KW-0181--Complete proteome
KW-1017--Isopeptide bond
KW-0472--Membrane
KW-1185--Reference proteome
KW-0832--Ubl conjugation

Interpro

IPR007239--Atg5

Pfam

PF04106--APG5

Gene Ontology

GO:0005776--C:autophagosome
GO:0005930--C:axoneme
GO:0044233--C:ER-mitochondrion membrane contact site
GO:0034045--C:pre-autophagosomal structure membrane
GO:0035973--P:aggrephagy
GO:0019883--P:antigen processing and presentation of endogenous antigen
GO:0001974--P:blood vessel remodeling
GO:0019725--P:cellular homeostasis
GO:0071500--P:cellular response to nitrosative stress
GO:0009267--P:cellular response to starvation
GO:0060047--P:heart contraction
GO:0000422--P:mitophagy
GO:0043066--P:negative regulation of apoptotic process
GO:2000619--P:negative regulation of histone H4-K16 acetylation
GO:0050765--P:negative regulation of phagocytosis
GO:0031397--P:negative regulation of protein ubiquitination
GO:2000378--P:negative regulation of reactive oxygen species metabolic process
GO:0039689--P:negative stranded viral RNA replication
GO:0045060--P:negative thymic T cell selection
GO:0048840--P:otolith development
GO:0070257--P:positive regulation of mucus secretion
GO:0061739--P:protein lipidation involved in autophagosome assembly
GO:1902017--P:regulation of cilium assembly
GO:0002739--P:regulation of cytokine secretion involved in immune response
GO:0051279--P:regulation of release of sequestered calcium ion into cytosol
GO:0042493--P:response to drug
GO:0009620--P:response to fungus
GO:0042311--P:vasodilation
GO:0055015--P:ventricular cardiac muscle cell development

Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000583 Aegilops tauschii 32.94 1.00e-24 108.00
IUUC-Aml-002403 Ailuropoda melanoleuca 97.83 2.00e-159 554.00
IUUC-Atr-002645 Amborella trichopoda 26.41 4.00e-23 102.00
IUUC-Apl-003611 Anas platyrhynchos 88.81 5.00e-151 526.00
IUUC-Aca-004411 Anolis carolinensis 89.21 3.00e-151 527.00
IUUC-Aly-005636 Arabidopsis lyrata 26.97 5.00e-27 115.00
IUUC-Ath-006959 Arabidopsis thaliana 27.27 4.00e-27 115.00
IUUC-Ago-007978 Ashbya gossypii 25.20 3.00e-08 52.40
IUUC-Acl-008328 Aspergillus clavatus 25.59 3.00e-19 88.60
IUUC-Afl-008638 Aspergillus flavus 30.66 6.00e-25 107.00
IUUC-Afu-009042 Aspergillus fumigatus 26.20 1.00e-25 110.00
IUUC-Ani-009364 Aspergillus nidulans 30.05 4.00e-24 105.00
IUUC-Aor-009889 Aspergillus oryzae 30.66 6.00e-25 107.00
IUUC-Ate-010511 Aspergillus terreus 32.26 7.00e-11 58.90
IUUC-Ame-011644 Astyanax mexicanus 87.34 7.00e-38 147.00
IUUC-Bgr-012153 Blumeria graminis 29.04 9.00e-19 87.00
IUUC-Bta-012360 Bos taurus 98.11 3.00e-87 313.00
IUUC-Bci-013723 Botrytis cinerea 27.84 3.00e-15 75.50
IUUC-Bdi-014520 Brachypodium distachyon 22.59 4.00e-21 95.50
IUUC-Bol-016053 Brassica oleracea 26.57 5.00e-29 121.00
IUUC-Bra-017072 Brassica rapa 26.95 3.00e-29 122.00
IUUC-Cel-018529 Caenorhabditis elegans 35.53 4.00e-38 151.00
IUUC-Cja-019569 Callithrix jacchus 97.83 1.00e-157 548.00
IUUC-Cfa-020473 Canis familiaris 97.11 7.00e-157 545.00
IUUC-Cpo-021421 Cavia porcellus 96.03 4.00e-155 540.00
IUUC-Cre-022862 Chlamydomonas reinhardtii 29.31 5.00e-18 84.30
IUUC-Csa-024197 Chlorocebus sabaeus 97.47 6.00e-157 546.00
IUUC-Cho-024521 Choloepus hoffmanni 94.61 2.00e-130 457.00
IUUC-Cin-025119 Ciona intestinalis 44.91 7.00e-64 236.00
IUUC-Csv-026192 Ciona savignyi 45.56 1.00e-64 239.00
IUUC-Cgl-026686 Colletotrichum gloeosporioides 24.77 8.00e-09 53.90
IUUC-Dre-028466 Danio rerio 80.14 5.00e-134 469.00
IUUC-Dse-031228 Dothistroma septosporum 27.27 1.00e-29 123.00
IUUC-Dme-031703 Drosophila melanogaster 48.35 5.00e-73 267.00
IUUC-Ete-032482 Echinops telfairi 96.27 2.00e-132 464.00
IUUC-Eca-034036 Equus caballus 97.11 6.00e-157 546.00
IUUC-Eeu-035235 Erinaceus europaeus 96.23 6.00e-86 310.00
IUUC-Fca-036263 Felis catus 97.11 1.00e-156 545.00
IUUC-Fal-037064 Ficedula albicollis 89.53 1.00e-151 528.00
IUUC-Fox-037813 Fusarium oxysporum 25.96 6.00e-15 74.30
IUUC-Fso-038139 Fusarium solani 26.48 2.00e-16 79.30
IUUC-Gmo-039509 Gadus morhua 79.65 1.00e-111 395.00
IUUC-Ggr-040111 Gaeumannomyces graminis 26.36 1.00e-13 70.10
IUUC-Gga-040517 Gallus gallus 88.81 6.00e-150 522.00
IUUC-Gac-042270 Gasterosteus aculeatus 77.60 2.00e-116 411.00
IUUC-Gma-044400 Glycine max 36.14 1.00e-23 103.00
IUUC-Ggo-045048 Gorilla gorilla 96.39 4.00e-155 540.00
IUUC-Hsa-046744 Homo sapiens 97.11 1.00e-156 545.00
IUUC-Kpa-049174 Komagataella pastoris 25.50 3.00e-14 72.40
IUUC-Lch-049475 Latimeria chalumnae 87.73 3.00e-146 510.00
IUUC-Lpe-051283 Leersia perrieri 34.75 3.00e-23 103.00
IUUC-Loc-052446 Lepisosteus oculatus 82.67 4.00e-140 489.00
IUUC-Lma-053278 Leptosphaeria maculans 27.36 1.00e-28 119.00
IUUC-Laf-054020 Loxodonta africana 97.83 8.00e-160 555.00
IUUC-Mcc-055176 Macaca mulatta 97.11 1.00e-156 545.00
IUUC-Mor-057164 Magnaporthe oryzae 27.17 9.00e-17 80.90
IUUC-Mpo-057428 Magnaporthe poae 28.31 1.00e-13 70.10
IUUC-Mtr-058424 Medicago truncatula 35.98 2.00e-23 102.00
IUUC-Mla-058872 Melampsora laricipopulina 29.41 2.00e-29 122.00
IUUC-Mga-059859 Meleagris gallopavo 88.81 6.00e-150 522.00
IUUC-Mmr-061482 Microcebus murinus 97.83 6.00e-158 549.00
IUUC-Mdo-062371 Monodelphis domestica 93.50 4.00e-157 546.00
IUUC-Mmu-063139 Mus musculus 96.75 4.00e-156 543.00
IUUC-Mac-065332 Musa acuminata 35.43 4.00e-26 112.00
IUUC-Mpu-066783 Mustela putorius furo 96.75 5.00e-156 543.00
IUUC-Mlu-068165 Myotis lucifugus 95.67 2.00e-156 544.00
IUUC-Nfi-068578 Neosartorya fischeri 26.98 1.00e-26 113.00
IUUC-Ncr-068636 Neurospora crassa 25.19 3.00e-11 62.80
IUUC-Nle-069740 Nomascus leucogenys 97.47 7.00e-157 545.00
IUUC-Opr-070802 Ochotona princeps 97.48 7.00e-86 310.00
IUUC-Ont-072222 Oreochromis niloticus 79.06 2.00e-134 471.00
IUUC-Oan-072760 Ornithorhynchus anatinus 93.40 1.00e-111 395.00
IUUC-Ocu-074844 Oryctolagus cuniculus 94.25 4.00e-96 343.00
IUUC-Oba-075834 Oryza barthii 32.77 2.00e-24 106.00
IUUC-Obr-076230 Oryza brachyantha 32.69 2.00e-14 73.20
IUUC-Ogl-077554 Oryza glaberrima 32.77 2.00e-24 106.00
IUUC-Ogu-078687 Oryza glumaepatula 32.77 1.00e-24 107.00
IUUC-Oin-079677 Oryza indica 25.51 7.00e-26 111.00
IUUC-Olo-081078 Oryza longistaminata 35.42 1.00e-24 107.00
IUUC-Ome-081548 Oryza meridionalis 33.33 2.00e-27 117.00
IUUC-Oni-082050 Oryza nivara 33.33 4.00e-25 108.00
IUUC-Opu-083609 Oryza punctata 33.15 3.00e-25 109.00
IUUC-Oru-085057 Oryza rufipogon 33.33 6.00e-25 108.00
IUUC-Osa-085917 Oryza sativa 33.33 7.00e-25 108.00
IUUC-Ola-087032 Oryzias latipes 78.70 2.00e-132 464.00
IUUC-Olu-087877 Ostreococcus lucimarinus 27.59 8.00e-04 36.20
IUUC-Oar-089751 Ovis aries 97.11 1.00e-156 545.00
IUUC-Ptr-091064 Pan troglodytes 97.11 1.00e-156 545.00
IUUC-Pan-092505 Papio anubis 98.19 2.00e-159 554.00
IUUC-Psi-093086 Pelodiscus sinensis 90.97 3.00e-154 536.00
IUUC-Pno-094825 Phaeosphaeria nodorum 28.27 6.00e-26 110.00
IUUC-Ppa-095419 Physcomitrella patens 32.53 3.00e-25 109.00
IUUC-Pfo-096224 Poecilia formosa 77.98 3.00e-132 464.00
IUUC-Pab-098501 Pongo abelii 97.11 9.00e-156 542.00
IUUC-Pop-099243 Populus trichocarpa 27.88 2.00e-24 106.00
IUUC-Ppe-101255 Prunus persica 26.48 1.00e-27 117.00
IUUC-Pva-102828 Pteropus vampyrus 96.03 6.00e-155 539.00
IUUC-Pgr-103672 Puccinia graminis 29.28 7.00e-26 111.00
IUUC-Ptt-104013 Puccinia triticina 27.58 5.00e-22 98.60
IUUC-Pyt-104615 Pyrenophora triticirepentis 27.83 2.00e-26 112.00
IUUC-Rno-106089 Rattus norvegicus 93.52 4.00e-133 466.00
IUUC-Sce-106216 Saccharomyces cerevisiae 24.16 2.00e-11 62.40
IUUC-Sha-106484 Sarcophilus harrisii 93.50 3.00e-157 546.00
IUUC-Sja-107699 Schizosaccharomyces japonicus 28.36 8.00e-27 113.00
IUUC-Spo-108177 Schizosaccharomyces pombe 28.29 3.00e-22 98.60
IUUC-Ssl-108475 Sclerotinia sclerotiorum 28.18 4.00e-15 74.70
IUUC-Smo-109473 Selaginella moellendorffii 26.61 1.00e-23 103.00
IUUC-Sit-110736 Setaria italica 33.51 6.00e-29 121.00
IUUC-Sly-111657 Solanum lycopersicum 37.20 3.00e-27 115.00
IUUC-Sar-113050 Sorex araneus 80.50 3.00e-105 374.00
IUUC-Sbi-114258 Sorghum bicolor 33.92 6.00e-26 111.00
IUUC-Sre-114902 Sporisorium reilianum 31.19 8.00e-23 101.00
IUUC-Ssc-116166 Sus scrofa 90.61 2.00e-146 511.00
IUUC-Tgu-116814 Taeniopygia guttata 88.81 3.00e-150 523.00
IUUC-Tru-118172 Takifugu rubripes 78.70 1.00e-132 464.00
IUUC-Tsy-119010 Tarsius syrichta 83.03 2.00e-132 464.00
IUUC-Tni-120397 Tetraodon nigroviridis 80.48 1.00e-101 362.00
IUUC-Tca-121283 Theobroma cacao 27.64 2.00e-28 119.00
IUUC-Tvi-122545 Trichoderma virens 24.57 3.00e-13 68.60
IUUC-Tae-122685 Triticum aestivum 32.16 2.00e-24 106.00
IUUC-Tur-126407 Triticum urartu 34.67 1.00e-24 107.00
IUUC-Tme-126913 Tuber melanosporum 31.71 5.00e-40 157.00
IUUC-Tbe-127738 Tupaia belangeri 90.40 3.00e-104 370.00
IUUC-Ttr-128528 Tursiops truncatus 97.11 3.00e-156 543.00
IUUC-Uma-129625 Ustilago maydis 27.65 4.00e-20 92.40
IUUC-Vda-129906 Verticillium dahliae 24.90 4.00e-11 61.60
IUUC-Vpa-130223 Vicugna pacos 96.03 8.00e-151 525.00
IUUC-Vvi-131617 Vitis vinifera 35.37 7.00e-25 107.00
IUUC-Xtr-132288 Xenopus tropicalis 86.28 6.00e-143 499.00
IUUC-Xma-134214 Xiphophorus maculatus 82.38 6.00e-97 346.00
IUUC-Yli-134377 Yarrowia lipolytica 24.63 8.00e-12 63.90
IUUC-Zma-135108 Zea mays 34.72 1.00e-23 103.00
Created Date 25-Jun-2017

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