iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093895

Ensembl Protein ID

ENSPSIP00000003352.1

UniProt Accession

K7F5P2; K7F5P2_PELSI

Genbank Protein ID

ENSPSIP00000003352

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

AGCU01038059

Gene Name

BLK

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000003210.1	ENSPSIT00000003368.1	ENSPSIP00000003352.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.20e-15	56.4	17	74

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           ++ v++ly++++++d +L+l kG++++++   + d++W+ +++ ++g++G +P+nFv++++
   Q: 17   ENIVIALYEFTSTSDRDLELVKGEKLQIL---NRDGDWWLAESLTTGRKGYIPSNFVARVD 74
           789**************************...9**************************97 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

VGGHLTPGVS FSLTADENIV IALYEFTSTS DRDLELVKGE KLQILNRDGD WWLAESLTTG 60
RKGYIPSNFV ARVDTLEMEK WYFNALSRKE AERLLMAPGN KIGSFLVRES ETTKGAFSLS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGGGGGGCC ACCTAACCCC AGGCGTGTCC TTTTCCCTTA CAGCAGATGA GAACATTGTG 60
ATTGCACTGT ACGAGTTCAC CTCCACCAGT GACCGCGACT TGGAGCTGGT CAAGGGAGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0050853--P:B cell receptor signaling pathway
GO:0032024--P:positive regulation of insulin secretion

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002133	Ailuropoda melanoleuca	74.46	0.00e+00	741.00
IUUC-Apl-003307	Anas platyrhynchos	85.59	0.00e+00	814.00
IUUC-Aca-004357	Anolis carolinensis	75.34	0.00e+00	721.00
IUUC-Ame-010642	Astyanax mexicanus	71.62	0.00e+00	705.00
IUUC-Bta-012400	Bos taurus	74.55	0.00e+00	733.00
IUUC-Cfa-021056	Canis familiaris	74.46	0.00e+00	740.00
IUUC-Cpo-021779	Cavia porcellus	75.67	0.00e+00	742.00
IUUC-Csa-023557	Chlorocebus sabaeus	74.62	0.00e+00	744.00
IUUC-Dre-027517	Danio rerio	73.38	0.00e+00	721.00
IUUC-Eca-034218	Equus caballus	73.28	0.00e+00	739.00
IUUC-Eeu-035095	Erinaceus europaeus	56.49	7.00e-151	526.00
IUUC-Fca-036015	Felis catus	73.10	0.00e+00	722.00
IUUC-Fal-036946	Ficedula albicollis	84.91	0.00e+00	810.00
IUUC-Gmo-038861	Gadus morhua	67.87	0.00e+00	646.00
IUUC-Gga-040822	Gallus gallus	83.22	0.00e+00	805.00
IUUC-Gac-041860	Gasterosteus aculeatus	65.73	0.00e+00	650.00
IUUC-Ggo-044608	Gorilla gorilla	74.71	0.00e+00	697.00
IUUC-Hsa-046719	Homo sapiens	73.71	0.00e+00	735.00
IUUC-Itr-048323	Ictidomys tridecemlineatus	74.61	0.00e+00	724.00
IUUC-Lch-050114	Latimeria chalumnae	75.39	0.00e+00	732.00
IUUC-Loc-052326	Lepisosteus oculatus	74.72	0.00e+00	721.00
IUUC-Laf-053387	Loxodonta africana	72.63	0.00e+00	729.00
IUUC-Mcc-055026	Macaca mulatta	74.62	0.00e+00	744.00
IUUC-Mga-059427	Meleagris gallopavo	83.30	0.00e+00	798.00
IUUC-Mmr-061660	Microcebus murinus	75.73	0.00e+00	736.00
IUUC-Mdo-062318	Monodelphis domestica	71.71	0.00e+00	723.00
IUUC-Mmu-063325	Mus musculus	73.44	0.00e+00	723.00
IUUC-Mpu-066582	Mustela putorius furo	74.03	0.00e+00	738.00
IUUC-Nle-069624	Nomascus leucogenys	75.78	0.00e+00	739.00
IUUC-Opr-070656	Ochotona princeps	70.76	0.00e+00	676.00
IUUC-Ont-072266	Oreochromis niloticus	71.59	0.00e+00	699.00
IUUC-Ocu-073907	Oryctolagus cuniculus	74.66	0.00e+00	730.00
IUUC-Ola-086668	Oryzias latipes	68.83	0.00e+00	667.00
IUUC-Oga-088057	Otolemur garnettii	75.11	0.00e+00	731.00
IUUC-Oar-089332	Ovis aries	69.03	0.00e+00	685.00
IUUC-Ptr-091551	Pan troglodytes	73.36	0.00e+00	702.00
IUUC-Pan-092173	Papio anubis	75.96	0.00e+00	739.00
IUUC-Pfo-096608	Poecilia formosa	70.82	0.00e+00	697.00
IUUC-Pab-097598	Pongo abelii	76.13	0.00e+00	738.00
IUUC-Pva-102135	Pteropus vampyrus	72.94	0.00e+00	727.00
IUUC-Rno-104891	Rattus norvegicus	73.66	0.00e+00	725.00
IUUC-Sha-107192	Sarcophilus harrisii	72.45	0.00e+00	726.00
IUUC-Ssc-115696	Sus scrofa	73.55	0.00e+00	740.00
IUUC-Tgu-117056	Taeniopygia guttata	84.88	0.00e+00	808.00
IUUC-Tru-117621	Takifugu rubripes	67.86	0.00e+00	665.00
IUUC-Ttr-128457	Tursiops truncatus	75.00	0.00e+00	731.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence