iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003529

Ensembl Protein ID

ENSAPLP00000001901.1

UniProt Accession

R0JEG9; R0JEG9_ANAPL

Genbank Protein ID

EOA95665.1

Protein Name

WD repeat, SAM and U-box domain-containing protein 1

Genbank Nucleotide ID

ADON01124710

Gene Name

WDSUB1; Anapl_12466

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000002463.1	ENSAPLT00000002479.1	ENSAPLP00000001901.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.50e-38	128.2	52	88
E3 activity/RING/U-box	5.30e-25	87.0	404	475
UBD/Beta-Prp	8.40e-55	185.7	3	217

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDlrtgvl 35
           gHt  v+c++f   ++ll+s+s Dgt +vWD+++g +
   Q: 52   GHTYAVHCCCFspLGHLLASCSTDGTTMVWDTHDGQV 88
           8**********853389***************99976 PP

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawceens 73
           +p+eflCpI+ elM++Pv++++G++y+++++e w++++++++P+t+ pl++ +l+Pn tl+  i++w+e+++
   Q: 404  IPDEFLCPITRELMKEPVIAADGYSYEKEAMENWISNKRRSSPMTNLPLHSLMLTPNRTLKMAISRWLETQQ 475
           8*******************************************************************9986 PP

UBD/Beta-Prp

   S: 43   kllrslsgheaevtavkfspdgkilvtgseDrtikvwdls..tgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcl 129
           +l+++l +h++ v+++ fsp+  +l+t+s D+t+++++ls  t    + lkgh++ v ++ fsp g+ l+s s d t +vwd++ gq+l
   Q: 3    TLIHTLADHSDDVNCCAFSPS--LLATCSLDKTVRIYSLSdfTELSYSPLKGHTYAVHCCCFSPLGHLLASCSTDGTTMVWDTHDGQVL 89
           5799*****************..9****************44444556799************************************** PP
   S: 130  eetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtl 218
             + ++  + v++ +++p++ +lvsG++D+ v lW++++ kl r  +  +++s    +f++ng+++v+gs  g++++wd  t +c++  
   Q: 90   AVLGQPSGSPVRVCRFSPESTYLVSGAADGSVVLWNVQSLKLYRSGSV-KDGSLVACAFSPNGNCFVTGSSWGDITIWDD-TMRCLYNE 176
           *777888899***********************************987.99999*************************9.888***** PP
   S: 219  nghtdnvksvrfs..........pnderlvsgssDgsiriW 249
           ++h+  v++ + s          ++   ++s+++D+ ++iW
   Q: 177  KAHDLGVTCCDISsqpisdgehgSRYFQMASCGQDNKVKIW 217
           ****9999999998888777544455568899999999999 PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

MATLIHTLAD HSDDVNCCAF SPSLLATCSL DKTVRIYSLS DFTELSYSPL KGHTYAVHCC 60
CFSPLGHLLA SCSTDGTTMV WDTHDGQVLA VLGQPSGSPV RVCRFSPEST YLVSGAADGS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCAACAT TAATTCACAC TTTAGCAGAT CACAGTGATG ATGTCAACTG CTGTGCCTTC 60
TCACCATCGC TCTTGGCTAC TTGTTCTTTG GACAAAACAG TTCGTATTTA TTCTTTAAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR011047--Quinoprotein_ADH-like_supfam
IPR001660--SAM
IPR013761--SAM/pointed
IPR003613--Ubox_domain
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50105--SAM_DOMAIN
PS51698--U_BOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07647--SAM_2
PF04564--U-box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00454--SAM
SM00504--Ubox
SM00320--WD40

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001614	Ailuropoda melanoleuca	76.26	0.00e+00	774.00
IUUC-Aca-004257	Anolis carolinensis	72.07	0.00e+00	719.00
IUUC-Ame-011357	Astyanax mexicanus	51.65	7.00e-116	410.00
IUUC-Bta-013032	Bos taurus	74.21	0.00e+00	748.00
IUUC-Cja-018743	Callithrix jacchus	75.63	0.00e+00	758.00
IUUC-Cfa-021197	Canis familiaris	75.42	0.00e+00	764.00
IUUC-Cpo-022279	Cavia porcellus	75.00	0.00e+00	755.00
IUUC-Csa-023954	Chlorocebus sabaeus	75.84	0.00e+00	760.00
IUUC-Cho-025083	Choloepus hoffmanni	61.64	1.00e-130	459.00
IUUC-Cin-025786	Ciona intestinalis	37.07	4.00e-85	308.00
IUUC-Dre-028087	Danio rerio	55.92	7.00e-144	503.00
IUUC-Dno-028919	Dasypus novemcinctus	75.63	0.00e+00	758.00
IUUC-Dor-031112	Dipodomys ordii	73.32	0.00e+00	729.00
IUUC-Ete-032405	Echinops telfairi	72.51	5.00e-150	523.00
IUUC-Eca-033254	Equus caballus	74.37	0.00e+00	750.00
IUUC-Eeu-034545	Erinaceus europaeus	72.69	0.00e+00	710.00
IUUC-Fca-035482	Felis catus	76.47	0.00e+00	771.00
IUUC-Fal-036976	Ficedula albicollis	70.37	0.00e+00	657.00
IUUC-Gmo-039213	Gadus morhua	55.30	1.00e-136	479.00
IUUC-Gga-040561	Gallus gallus	85.53	0.00e+00	857.00
IUUC-Gac-041471	Gasterosteus aculeatus	58.44	8.00e-138	483.00
IUUC-Ggo-045503	Gorilla gorilla	75.63	0.00e+00	759.00
IUUC-Hsa-045910	Homo sapiens	75.84	0.00e+00	761.00
IUUC-Itr-048214	Ictidomys tridecemlineatus	74.27	1.00e-168	585.00
IUUC-Loc-052307	Lepisosteus oculatus	57.68	2.00e-168	585.00
IUUC-Laf-053587	Loxodonta africana	75.00	0.00e+00	754.00
IUUC-Mcc-055679	Macaca mulatta	75.63	0.00e+00	758.00
IUUC-Meu-055962	Macropus eugenii	65.55	1.00e-174	605.00
IUUC-Mga-059652	Meleagris gallopavo	84.28	0.00e+00	845.00
IUUC-Mmr-060943	Microcebus murinus	72.59	0.00e+00	731.00
IUUC-Mdo-062592	Monodelphis domestica	74.53	0.00e+00	756.00
IUUC-Mmu-063577	Mus musculus	71.64	0.00e+00	713.00
IUUC-Mpu-066422	Mustela putorius furo	75.63	0.00e+00	768.00
IUUC-Mlu-067250	Myotis lucifugus	74.58	0.00e+00	751.00
IUUC-Nle-069517	Nomascus leucogenys	75.84	0.00e+00	759.00
IUUC-Opr-070776	Ochotona princeps	74.16	0.00e+00	735.00
IUUC-Ont-071821	Oreochromis niloticus	58.02	6.00e-148	516.00
IUUC-Oan-073706	Ornithorhynchus anatinus	76.21	0.00e+00	769.00
IUUC-Ocu-074766	Oryctolagus cuniculus	68.18	0.00e+00	660.00
IUUC-Ola-086531	Oryzias latipes	56.26	7.00e-142	496.00
IUUC-Oga-088388	Otolemur garnettii	74.16	0.00e+00	751.00
IUUC-Oar-089748	Ovis aries	74.42	0.00e+00	747.00
IUUC-Ptr-090616	Pan troglodytes	75.69	0.00e+00	755.00
IUUC-Pan-091769	Papio anubis	74.34	3.00e-153	534.00
IUUC-Psi-093334	Pelodiscus sinensis	81.09	0.00e+00	770.00
IUUC-Pma-094383	Petromyzon marinus	48.83	4.00e-132	464.00
IUUC-Pfo-096801	Poecilia formosa	55.49	3.00e-143	501.00
IUUC-Pab-098139	Pongo abelii	74.04	2.00e-174	604.00
IUUC-Pca-100523	Procavia capensis	65.34	0.00e+00	634.00
IUUC-Pva-102286	Pteropus vampyrus	75.00	0.00e+00	734.00
IUUC-Rno-104831	Rattus norvegicus	71.85	0.00e+00	722.00
IUUC-Sha-107499	Sarcophilus harrisii	76.26	0.00e+00	768.00
IUUC-Sar-113389	Sorex araneus	74.16	0.00e+00	724.00
IUUC-Tgu-116769	Taeniopygia guttata	82.56	0.00e+00	823.00
IUUC-Tru-118774	Takifugu rubripes	53.50	7.00e-137	480.00
IUUC-Tsy-119595	Tarsius syrichta	64.48	4.00e-146	510.00
IUUC-Tni-119850	Tetraodon nigroviridis	56.45	5.00e-144	503.00
IUUC-Tbe-127938	Tupaia belangeri	68.09	3.00e-120	424.00
IUUC-Ttr-128193	Tursiops truncatus	74.76	0.00e+00	637.00
IUUC-Vpa-130275	Vicugna pacos	76.26	0.00e+00	764.00
IUUC-Xtr-131982	Xenopus tropicalis	62.32	3.00e-172	597.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence