iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Xtr-132773

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitin-specific peptidase 38

Genbank Nucleotide ID

AAMC01099346

Gene Name

usp38

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000017515.3	ENSXETT00000038065.3	ENSXETP00000038065.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.70e-78	262.6	444	931

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           tGl NlgNtCYmNSvLQ+L++ +++r+++l+    +ln +      ++l+k+lq+lf+ l +++++a++p+++++a +   + f+  +q
   Q: 444  TGLINLGNTCYMNSVLQALFMATDFRRQVLS---LNLNGT------NSLMKKLQHLFAFLAHTQREAYAPQTFFDASR--PPWFTPRSQ 521
           7******************************...666655......58***************************998..777****** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.........aeekkkkknkslisdlFqgqlksqikclecdnvssreepf 169
           qD++E+l+flld+l + ++   + ++++   e++s++ ++          ++   +k+ksli+++F+g+l+++i cl+c+++s+++e f
   Q: 522  QDCSEYLRFLLDRLGSLFQLPLDASVHDCIVEESSASVSDdisnhyctkGSKGCGNKEKSLIENMFGGKLQTNICCLNCRSTSQKREAF 610
           ****************9977555555554444433333334677788778888999999****************************** PP
   S: 170  ldlslpvpgkeetkke......................................................................... 185
           +dlsl++      k+                                                                          
   Q: 611  TDLSLAFCPTLVDKPVqstlgspkqkddddcietdiasstlapstedvnvgpeneiseceevktnvscvldnsvcanaiesdemptqnn 699
           ********88876665889999******************************************************************* PP
   S: 186  ......slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlsp.fcts 267
                 s++d+L+ f ++e l+g+n+yycekc ++q+a+k++++ + Pe+Lil L Rfs++ + ++r+ki ++v++pl L+l    +ts
   Q: 700  rrertlSVTDLLNYFLAPEILDGDNQYYCEKCASLQNAKKTMQIMEEPEYLILTLLRFSYDPKCHVRRKIMDNVSIPLVLELPVeRTTS 788
           *****************************************************************************999998524444 PP
   S: 268  .....peekqke.............................kkkYeLiavvvHsG.slssGHYvayvkn.................... 301
                +                                   ++ Y L++vvvHsG s++sGHY++y++n                    
   Q: 789  ptspgD-----WtletdipdvsenlakklkpsntedlccshPVPYVLSSVVVHSGtSSESGHYYSYARNvtsterclyaekscyshgql 872
           444440.....155566666666666667777777788888**********************************************99 PP
   S: 302  ...................ekgkWllfdDskVtevkeeevleetg....staYvlfYkr 337
                               +++W+lf+Ds+Vt ++ ++vl+ t+    +taYvl+Y++
   Q: 873  veretgssvmthkdtqcndISKEWFLFNDSRVTFTSFQSVLNITSrfpkDTAYVLIYRK 931
           99999999999988777666777*******************999************97 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

MDKILEGLVT SSHPLNLKKV IVKKVVESAE NSVSEEQCKA MFSLTTRLIL EGQDPFQKQV 60
GHQVLEAYAR YHRSEFENYF NRNFVLSLLQ EGYRSLERKD VAILDYIHNG LKLIMSCPSI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACAAGA TTCTGGAAGG ATTGGTGACC TCTTCGCATC CATTAAATCT GAAAAAAGTC 60
ATAGTAAAGA AAGTTGTGGA ATCAGCTGAA AATTCAGTCA GTGAAGAACA ATGCAAGGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016024--ARM-type_fold
IPR001394--Peptidase_C19_UCH
IPR033840--USP38
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002174	Ailuropoda melanoleuca	72.28	0.00e+00	1347.00
IUUC-Apl-003435	Anas platyrhynchos	67.84	0.00e+00	1111.00
IUUC-Aca-004556	Anolis carolinensis	64.31	0.00e+00	1194.00
IUUC-Ame-010616	Astyanax mexicanus	60.44	0.00e+00	1177.00
IUUC-Bta-013544	Bos taurus	72.50	0.00e+00	1367.00
IUUC-Cja-018745	Callithrix jacchus	71.85	0.00e+00	1384.00
IUUC-Cfa-020434	Canis familiaris	69.41	0.00e+00	1302.00
IUUC-Cpo-021666	Cavia porcellus	72.27	0.00e+00	1326.00
IUUC-Csa-023965	Chlorocebus sabaeus	73.12	0.00e+00	1436.00
IUUC-Cho-024809	Choloepus hoffmanni	62.09	0.00e+00	876.00
IUUC-Cin-025604	Ciona intestinalis	30.87	2.00e-42	166.00
IUUC-Dre-028338	Danio rerio	61.03	0.00e+00	1197.00
IUUC-Dno-029372	Dasypus novemcinctus	72.07	0.00e+00	1381.00
IUUC-Dor-030752	Dipodomys ordii	68.08	0.00e+00	872.00
IUUC-Dme-031871	Drosophila melanogaster	29.65	1.00e-45	178.00
IUUC-Ete-032588	Echinops telfairi	60.51	0.00e+00	811.00
IUUC-Eca-034416	Equus caballus	72.13	0.00e+00	1406.00
IUUC-Eeu-035132	Erinaceus europaeus	56.62	0.00e+00	1007.00
IUUC-Fca-036137	Felis catus	72.92	0.00e+00	1414.00
IUUC-Fal-037297	Ficedula albicollis	67.02	0.00e+00	1270.00
IUUC-Gmo-038727	Gadus morhua	62.77	0.00e+00	956.00
IUUC-Gga-041091	Gallus gallus	67.14	0.00e+00	1231.00
IUUC-Gac-042082	Gasterosteus aculeatus	60.81	0.00e+00	1077.00
IUUC-Ggo-045376	Gorilla gorilla	68.50	0.00e+00	1295.00
IUUC-Hsa-046444	Homo sapiens	72.43	0.00e+00	1422.00
IUUC-Itr-047976	Ictidomys tridecemlineatus	72.11	0.00e+00	1405.00
IUUC-Lch-050500	Latimeria chalumnae	69.48	0.00e+00	1357.00
IUUC-Loc-052625	Lepisosteus oculatus	63.58	0.00e+00	1244.00
IUUC-Laf-053689	Loxodonta africana	71.36	0.00e+00	1380.00
IUUC-Mcc-055286	Macaca mulatta	72.91	0.00e+00	1417.00
IUUC-Meu-056906	Macropus eugenii	47.96	2.00e-179	623.00
IUUC-Mga-059905	Meleagris gallopavo	67.21	0.00e+00	1085.00
IUUC-Mmr-061397	Microcebus murinus	72.67	0.00e+00	1374.00
IUUC-Mdo-062833	Monodelphis domestica	72.40	0.00e+00	1430.00
IUUC-Mmu-063157	Mus musculus	71.85	0.00e+00	1364.00
IUUC-Mpu-066434	Mustela putorius furo	72.81	0.00e+00	1399.00
IUUC-Mlu-068178	Myotis lucifugus	71.09	0.00e+00	1316.00
IUUC-Nle-070153	Nomascus leucogenys	72.07	0.00e+00	1348.00
IUUC-Opr-070454	Ochotona princeps	42.57	1.00e-63	238.00
IUUC-Ont-072330	Oreochromis niloticus	61.32	0.00e+00	1180.00
IUUC-Oan-072709	Ornithorhynchus anatinus	69.53	0.00e+00	1075.00
IUUC-Ocu-074832	Oryctolagus cuniculus	72.92	0.00e+00	1360.00
IUUC-Ola-087003	Oryzias latipes	53.71	1.00e-45	175.00
IUUC-Oga-088517	Otolemur garnettii	70.88	0.00e+00	1345.00
IUUC-Oar-089472	Ovis aries	69.41	0.00e+00	1288.00
IUUC-Ptr-090996	Pan troglodytes	72.24	0.00e+00	1420.00
IUUC-Pan-091837	Papio anubis	71.32	0.00e+00	1375.00
IUUC-Psi-093236	Pelodiscus sinensis	67.92	0.00e+00	1030.00
IUUC-Pma-094349	Petromyzon marinus	50.48	0.00e+00	914.00
IUUC-Pfo-097193	Poecilia formosa	60.95	0.00e+00	1114.00
IUUC-Pab-098710	Pongo abelii	73.09	0.00e+00	1436.00
IUUC-Pca-100794	Procavia capensis	62.85	0.00e+00	1180.00
IUUC-Pva-102722	Pteropus vampyrus	71.69	0.00e+00	1384.00
IUUC-Rno-105743	Rattus norvegicus	71.55	0.00e+00	1360.00
IUUC-Sha-106563	Sarcophilus harrisii	69.88	0.00e+00	1134.00
IUUC-Sar-113533	Sorex araneus	64.17	0.00e+00	1197.00
IUUC-Ssc-116259	Sus scrofa	86.43	0.00e+00	874.00
IUUC-Tgu-117475	Taeniopygia guttata	67.93	0.00e+00	1159.00
IUUC-Tru-118623	Takifugu rubripes	60.14	0.00e+00	1076.00
IUUC-Tsy-119250	Tarsius syrichta	69.14	0.00e+00	1036.00
IUUC-Tni-120441	Tetraodon nigroviridis	56.11	0.00e+00	1004.00
IUUC-Tbe-127936	Tupaia belangeri	62.29	0.00e+00	1079.00
IUUC-Ttr-128483	Tursiops truncatus	61.65	0.00e+00	980.00
IUUC-Vpa-130303	Vicugna pacos	86.52	0.00e+00	947.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence