iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000019654.4	ENSCAFT00000046826.2	ENSCAFP00000039898.1
ENSCAFG00000019654.4	ENSCAFT00000031245.3	ENSCAFP00000029076.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.80e-38	128.1	700	736
UBD/Beta-Prp	1.40e-81	274.2	1356	1660

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sdtllvsGsdDgtikvWDlrtgvll 36
           Ht++v +la   s + l++ s D+t++vWDl t  +l
   Q: 700  HTAPVLALATecSHGQLATVSQDHTVRVWDLATLQQL 736
           9999999998865599***************987766 PP

UBD/Beta-Prp

   S: 14   tcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvw......dls........tgkc 86
           t++++    +ll  gs  g + vwd++   ++   + +++e+  + +s +   lv+gs+ r +++w      +          +++ 
   Q: 1356 TSLCY-GAAPLLYCGSNAGQVCVWDTSASRCFLAWEADDGEIGVLLCSGT--RLVSGSNTRRLRLWavgavpE-LrckdsrarSSSV 1438
           55555.66788999999999999999999999999999999999999999..699999999999996665551.0455555555555 PP
   S: 87   vhtlk.ghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkll 172
           ++  +   +  v+s  f+ + d  v+G+   t+    + +g+  + + sgh++ vn vv++p+++  +++s+D+ vr+W+l++++ll
   Q: 1439 FMERElTLDGAVVSAVFHDTMDMGVVGTTAGTLWYVSWVEGSSTR-LISGHRSKVNEVVFSPSASHWATCSDDGSVRVWSLASMELL 1524
           655556788999999999999999999999999997778888888.99*************************************** PP
   S: 173  rtltgghtdsvyslsfdsng......kelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrs 253
            +++   ++s  +l++++ +      +++++g  dgt++++++++  +  +++ h++  + ++ s +++ ++sg +Dg + +   r+
   Q: 1525 IQFQV-LNQSCLCLAWSPAScarpeqQQVAAGYSDGTLRVFSISRIAMELKMHPHRAALTAIAYSADGQTILSGDKDGLVAVSRPRT 1610
           ***98.*********77777777777************************************************************* PP
   S: 254  gdllktlqlhnssvisvav.lsfgdnvl........vlgsedskvniwkl 294
           g + ++l+ h+  +is     s ++  +        +++s+d+++ +w+ 
   Q: 1611 GMTFRVLSDHRGALISTVQsRSKEHGDFgaqwgdlwLAASSDQRISVWAA 1660
           ***********5555544423334444455666665999999****9985 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

AAWQRPFVNV FRHCRVGEWR RCSREGDVAA VTDKSLRCAV YRIRDAPSAG GYIQLPGTSM 60
QSLGLTGHYL YVLFRPLPGK HFIIQLDVAT KDGQVVRMSF SNLFKEFKST ATWLQFPLIC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACTTTGTGCC CATTGACCTG GACGAGTGGT GGGCGCAGCA GTTCCTGGCC AGGATCACGA 60
ACTGCTCCTA GCTGCCTTGT GAGGAATGCT GCCGTGCAGG GCTCAGCCCT GCCCAGGGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR007714--CFA20/WDR90/C3orf67
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR030466--WDR90

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF05018--DUF667
PF00400--WD40

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001801	Ailuropoda melanoleuca	82.91	0.00e+00	2842.00
IUUC-Apl-003387	Anas platyrhynchos	54.44	0.00e+00	1687.00
IUUC-Aca-005235	Anolis carolinensis	51.48	0.00e+00	1573.00
IUUC-Ame-011595	Astyanax mexicanus	47.75	0.00e+00	1326.00
IUUC-Bta-012328	Bos taurus	71.22	0.00e+00	2339.00
IUUC-Cja-019058	Callithrix jacchus	65.01	0.00e+00	1122.00
IUUC-Cpo-022025	Cavia porcellus	64.51	0.00e+00	2161.00
IUUC-Cre-022928	Chlamydomonas reinhardtii	29.52	2.00e-57	219.00
IUUC-Csa-023022	Chlorocebus sabaeus	66.79	0.00e+00	2167.00
IUUC-Cin-025133	Ciona intestinalis	34.27	0.00e+00	1093.00
IUUC-Csv-025816	Ciona savignyi	34.01	0.00e+00	963.00
IUUC-Dre-028823	Danio rerio	45.36	0.00e+00	1545.00
IUUC-Dno-029211	Dasypus novemcinctus	71.35	0.00e+00	936.00
IUUC-Dor-030211	Dipodomys ordii	66.25	0.00e+00	1909.00
IUUC-Ete-032363	Echinops telfairi	61.31	1.00e-133	470.00
IUUC-Eca-034296	Equus caballus	73.58	0.00e+00	2446.00
IUUC-Eeu-035226	Erinaceus europaeus	61.57	1.00e-165	577.00
IUUC-Fca-035384	Felis catus	78.52	0.00e+00	2719.00
IUUC-Fal-037660	Ficedula albicollis	53.11	0.00e+00	1679.00
IUUC-Gga-040666	Gallus gallus	56.95	0.00e+00	1298.00
IUUC-Gac-041358	Gasterosteus aculeatus	45.99	0.00e+00	1486.00
IUUC-Ggo-045121	Gorilla gorilla	66.24	0.00e+00	2179.00
IUUC-Hsa-046289	Homo sapiens	65.31	0.00e+00	2060.00
IUUC-Itr-048485	Ictidomys tridecemlineatus	67.36	0.00e+00	2162.00
IUUC-Lch-050009	Latimeria chalumnae	47.43	0.00e+00	1607.00
IUUC-Loc-052629	Lepisosteus oculatus	41.53	0.00e+00	875.00
IUUC-Mcc-055834	Macaca mulatta	62.40	0.00e+00	1160.00
IUUC-Meu-056162	Macropus eugenii	56.97	0.00e+00	760.00
IUUC-Mga-060167	Meleagris gallopavo	52.48	0.00e+00	1558.00
IUUC-Mmr-060761	Microcebus murinus	73.68	1.00e-128	452.00
IUUC-Mdo-061886	Monodelphis domestica	55.28	0.00e+00	2024.00
IUUC-Mmu-063652	Mus musculus	66.49	0.00e+00	2325.00
IUUC-Mlu-068141	Myotis lucifugus	70.35	0.00e+00	2394.00
IUUC-Nle-069133	Nomascus leucogenys	61.41	0.00e+00	1321.00
IUUC-Ont-072496	Oreochromis niloticus	47.03	0.00e+00	1641.00
IUUC-Oan-072833	Ornithorhynchus anatinus	49.76	0.00e+00	856.00
IUUC-Ola-086564	Oryzias latipes	45.94	0.00e+00	1534.00
IUUC-Oga-088919	Otolemur garnettii	62.89	0.00e+00	2129.00
IUUC-Oar-089946	Ovis aries	69.35	0.00e+00	1213.00
IUUC-Ptr-090755	Pan troglodytes	66.95	0.00e+00	1833.00
IUUC-Pan-092054	Papio anubis	66.08	0.00e+00	2172.00
IUUC-Psi-093467	Pelodiscus sinensis	55.60	0.00e+00	1922.00
IUUC-Pma-094553	Petromyzon marinus	43.20	0.00e+00	1285.00
IUUC-Pfo-096849	Poecilia formosa	45.72	0.00e+00	1434.00
IUUC-Pab-098320	Pongo abelii	65.60	0.00e+00	1934.00
IUUC-Pca-100172	Procavia capensis	57.88	0.00e+00	1095.00
IUUC-Pva-102772	Pteropus vampyrus	70.10	0.00e+00	1336.00
IUUC-Rno-105046	Rattus norvegicus	66.90	0.00e+00	2352.00
IUUC-Sha-107094	Sarcophilus harrisii	55.63	0.00e+00	2065.00
IUUC-Ssc-116257	Sus scrofa	66.49	0.00e+00	2149.00
IUUC-Tgu-117323	Taeniopygia guttata	52.43	0.00e+00	1416.00
IUUC-Tru-118717	Takifugu rubripes	43.51	0.00e+00	1456.00
IUUC-Tni-120108	Tetraodon nigroviridis	42.78	0.00e+00	832.00
IUUC-Ttr-128378	Tursiops truncatus	81.68	0.00e+00	1016.00
IUUC-Xtr-131760	Xenopus tropicalis	47.88	0.00e+00	1590.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence