iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Gga-041178

Ensembl Protein ID

ENSGALP00000014760.6

UniProt Accession

E1BRP5; E1BRP5_CHICK

Genbank Protein ID

ENSGALP00000014760

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AADN04000061

Gene Name

ZNF106

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000009081.6	ENSGALT00000014776.6	ENSGALP00000014760.6

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.30e-16	59.1	1547	1586
UBD/Beta-Prp	2.10e-50	172.0	1502	1708

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sdtl...lvsGsdDgtikvWDlrtgvl 35
           gHt++v+cl     ++     l +Gs D+ti +++++t  +
   Q: 1547 GHTSKVNCLLVtqtNG-KnaaLYTGSSDHTINCYNIKTKEC 1586
           8*******95587533.34579*************999877 PP

UBD/Beta-Prp

   S: 45   lrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp...sgdklvsGshdrtirvwdletgqc 128
             s++gh a+v+a+++  +  +l t+s D+t++ ++l ++kcv +++gh+++v +l + +   ++  l +Gs+d ti++++++t++c
   Q: 1502 EGSFEGHLAAVNAIQIFGN--LLYTCSADKTVCAYNLVSRKCVAVFEGHTSKVNCLLVTQtngKNAALYTGSSDHTINCYNIKTKEC 1586
           5789*************99..9*********************************99999744458899****************** PP
   S: 129  leetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsng..kelvsgsldgtvklwdlqtge 213
           +e  ++ +d   +++++h+  ++l +G +++ v  +++k++k ++t++    ++v +l+  ++g  k lv gs+d t+ + d ++g 
   Q: 1587 ME-QFKLED---RVLCLHSRWRILYAGLANGSVVTFNIKNNKQVDTFECHSPRAVSCLATAQEGarKLLVVGSYDCTISVRDARNGL 1669
           *9.555555...455566666**************************9989999*****99999999******************** PP
   S: 214  cvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsg 254
            +rtl+gh+++++++++   ++++ sgssD+s+  +++ +g
   Q: 1670 LLRTLEGHSKTILCMKVV--NDLVFSGSSDQSVHAHNIHTG 1708
           ******************..9****************9987 PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

MVRERKCILC HIVYSSKKEM EEHMRSMLHH RELENLKGRD SNHECQVCRV TLVGLSAYAK 60
HISSQLHKDN VDAHDKAEEK EEAEEEYLDK ELIQLIKQRK ERNRQVEQCC TNQETECDDR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTGCGAG AACGGAAATG CATACTGTGT CACATTGTAT ACAGCTCAAA AAAGGTAAAT 60
AATTCATACT TAGTTCACAT TTAACATCAG TAGGTACTAA TATTAAATGT GTATGAGAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0853--WD repeat
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003604--Matrin/U1-like-C_Znf_C2H2
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR013087--Znf_C2H2_type

PROSITE

PS50294--WD_REPEATS_REGION
PS00028--ZINC_FINGER_C2H2_1

Pfam

PF00400--WD40

SMART

SM00320--WD40
SM00355--ZnF_C2H2
SM00451--ZnF_U1

Gene Ontology

GO:0005829--C:cytosol
GO:0016020--C:membrane
GO:0003723--F:RNA binding
GO:0017124--F:SH3 domain binding
GO:0008270--F:zinc ion binding
GO:0008286--P:insulin receptor signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001928	Ailuropoda melanoleuca	56.18	0.00e+00	1751.00
IUUC-Apl-003674	Anas platyrhynchos	84.69	0.00e+00	2907.00
IUUC-Aca-005018	Anolis carolinensis	56.87	0.00e+00	1751.00
IUUC-Ame-011431	Astyanax mexicanus	69.23	0.00e+00	670.00
IUUC-Bta-013436	Bos taurus	58.02	0.00e+00	1843.00
IUUC-Cfa-020278	Canis familiaris	51.77	0.00e+00	1282.00
IUUC-Cpo-022278	Cavia porcellus	54.21	0.00e+00	1693.00
IUUC-Csa-023115	Chlorocebus sabaeus	80.88	0.00e+00	949.00
IUUC-Cho-024829	Choloepus hoffmanni	47.71	0.00e+00	972.00
IUUC-Dre-028112	Danio rerio	59.78	0.00e+00	662.00
IUUC-Dno-029127	Dasypus novemcinctus	58.99	0.00e+00	1811.00
IUUC-Dor-030367	Dipodomys ordii	64.15	0.00e+00	906.00
IUUC-Ete-032500	Echinops telfairi	62.00	0.00e+00	835.00
IUUC-Eca-034319	Equus caballus	57.35	0.00e+00	1815.00
IUUC-Eeu-034754	Erinaceus europaeus	51.98	0.00e+00	1368.00
IUUC-Fca-036181	Felis catus	57.40	0.00e+00	1707.00
IUUC-Fal-036865	Ficedula albicollis	76.80	0.00e+00	2489.00
IUUC-Gmo-039227	Gadus morhua	66.58	3.00e-171	595.00
IUUC-Gac-042209	Gasterosteus aculeatus	68.89	3.00e-163	568.00
IUUC-Ggo-044636	Gorilla gorilla	57.68	0.00e+00	1831.00
IUUC-Hsa-045949	Homo sapiens	57.08	0.00e+00	1755.00
IUUC-Itr-048628	Ictidomys tridecemlineatus	56.30	0.00e+00	1739.00
IUUC-Lch-049753	Latimeria chalumnae	49.60	0.00e+00	1406.00
IUUC-Loc-052333	Lepisosteus oculatus	69.65	0.00e+00	709.00
IUUC-Laf-053530	Loxodonta africana	57.03	0.00e+00	1807.00
IUUC-Mcc-054664	Macaca mulatta	56.69	0.00e+00	1736.00
IUUC-Meu-056609	Macropus eugenii	61.28	0.00e+00	894.00
IUUC-Mga-059632	Meleagris gallopavo	94.63	0.00e+00	3236.00
IUUC-Mmr-060742	Microcebus murinus	56.74	0.00e+00	1698.00
IUUC-Mdo-061831	Monodelphis domestica	66.91	0.00e+00	1134.00
IUUC-Mmu-064055	Mus musculus	54.94	0.00e+00	1643.00
IUUC-Mpu-066458	Mustela putorius furo	71.06	0.00e+00	1114.00
IUUC-Mlu-067767	Myotis lucifugus	57.84	0.00e+00	1802.00
IUUC-Nle-069728	Nomascus leucogenys	56.69	0.00e+00	1764.00
IUUC-Opr-070914	Ochotona princeps	54.78	0.00e+00	1668.00
IUUC-Ont-072353	Oreochromis niloticus	69.27	0.00e+00	633.00
IUUC-Ocu-073827	Oryctolagus cuniculus	57.22	0.00e+00	1706.00
IUUC-Ola-087573	Oryzias latipes	68.23	3.00e-161	561.00
IUUC-Oga-088664	Otolemur garnettii	65.41	0.00e+00	1244.00
IUUC-Oar-090256	Ovis aries	52.30	0.00e+00	1229.00
IUUC-Ptr-090884	Pan troglodytes	58.50	0.00e+00	1544.00
IUUC-Pan-091779	Papio anubis	80.88	0.00e+00	948.00
IUUC-Psi-093267	Pelodiscus sinensis	95.27	3.00e-166	576.00
IUUC-Pma-094414	Petromyzon marinus	40.07	1.00e-50	194.00
IUUC-Pfo-097009	Poecilia formosa	64.52	2.00e-158	553.00
IUUC-Pca-100820	Procavia capensis	49.24	0.00e+00	1029.00
IUUC-Pva-103044	Pteropus vampyrus	93.01	0.00e+00	765.00
IUUC-Rno-105960	Rattus norvegicus	52.00	0.00e+00	1540.00
IUUC-Sar-113018	Sorex araneus	72.32	0.00e+00	830.00
IUUC-Ssc-115278	Sus scrofa	58.14	0.00e+00	1837.00
IUUC-Tgu-117231	Taeniopygia guttata	76.84	0.00e+00	2617.00
IUUC-Tru-118472	Takifugu rubripes	56.85	1.00e-157	550.00
IUUC-Tsy-118877	Tarsius syrichta	92.86	0.00e+00	682.00
IUUC-Tni-119881	Tetraodon nigroviridis	56.59	5.00e-174	605.00
IUUC-Tbe-127499	Tupaia belangeri	45.36	0.00e+00	652.00
IUUC-Ttr-128962	Tursiops truncatus	57.29	0.00e+00	1711.00
IUUC-Vpa-130089	Vicugna pacos	57.91	0.00e+00	681.00
IUUC-Xtr-132940	Xenopus tropicalis	48.30	0.00e+00	1382.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence