iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004836

UUCD1 version

UUC-AnC-00972

Ensembl Protein ID

ENSACAP00000012153.2

UniProt Accession

H9GIU6; H9GIU6_ANOCA

Protein Name

Uncharacterized protein

Gene Name

BAP1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000012334.3	ENSACAT00000012399.3	ENSACAP00000012153.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/UCH	8.30e-158	525.2	11	733

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/UCH

   S: 14   dPglftllvedfgvkrdiqveelysLdpenlglyqepvegllllFkinekressrksqvtsndlevvdediiktiffakqvigNsCaty 102
            +glftllvedfgvk++ qvee+y+L++++    q+pv+g+++lFk++e+r+s+rk+++++++++v+dedi++++ffa+q+i+NsCat+
   Q: 11   FAGLFTLLVEDFGVKGV-QVEEIYDLQSKC----QGPVYGFIFLFKWIEERRSRRKVSTLVDETSVIDEDIVNNMFFAHQLIPNSCATH 94
           579**************.************....******************************************************* PP
   S: 103  AllsvllncedklldlGttlsrlkestkaespenkalalgnqqvlecihnslariesrseperqdedneqytkeafhfvsyvningrly 191
           Allsvllnc+++  dlG+tlsr+ke+tk++spe+k++a+gn+++l+++hns+ar+e+r++pe+q++ ++++t+eafhfvsyv+i+grl+
   Q: 95   ALLSVLLNCNSV--DLGPTLSRMKEFTKGFSPESKGYAIGNAPELAKAHNSHARPEPRHLPEKQNGISAVRTMEAFHFVSYVPIKGRLF 181
           ************..*************************************************************************** PP
   S: 192  eldglkpfPldl..gkkketeelkdklkvvraflerikllesde....irfnllaivadrrviktlrlnvlkid............... 259
           eldglk++P+d+  g++ e+ee++dk+++v+  +eri+l++++e    irfnl+a+v+drrv+++ +l++lk++               
   Q: 182  ELDGLKVYPIDHvsGPWAEDEEWTDKARRVI--MERIGLATAGEpyhdIRFNLMAVVPDRRVKYESKLQILKMNrqtvlealqqlirvt 268
           ***********98899***************..******************************************************** PP
   S: 260  ......................................................................................... 259
                                                                                                    
   Q: 269  qpelvhtqkaqesqaseepkpvnsktsstaletgrvqliaensqagtteepgsqkppastlsppskaktdskmpvssingalsnlnpiv 357
           ***************************************************************************************** PP
   S: 260  ......................................................................................... 259
                                                                                                    
   Q: 358  qrlpafldnhnyakspmqeeedlaagvgrnrvpvrqhqqysddeddyddeeeeevcnaspamsdqrkgqgkhehlvgsgdgklsmlqpn 446
           ***************************************************************************************** PP
   S: 260  ......................................................................................... 259
                                                                                                    
   Q: 447  tisvlteklketqkdlsiplsiktssggsavamvvhsqpsptpsnestdtaseigsafnsplrspirsanptrpsspvtshiskvlfgd 535
           ***************************************************************************************** PP
   S: 260  ......................................................................................... 259
                                                                                                    
   Q: 536  edsllrvdcirynravkdlgpiistgllhltedgvfgsltvtdggkssspsskvneevqsivkleerdlnerndsndskektgiarstn 624
           ***************************************************************************************** PP
   S: 260  .........keLlkLlkdieseeekieaqlddekekrkkfkiddirRtenydeficifikdlaregilrklveetisevrefgvnegrl 339
                    keLl+Llk++e+e++++ea+l++e+ekrkkfkidd+rRt+nydefic+fi++la+eg+l+ lve++is++r++gv++grl
   Q: 625  apvgekyspKELLALLKCVEAEIANYEACLKEEVEKRKKFKIDDQRRTHNYDEFICTFISMLAQEGMLASLVEQNISVRRRQGVSIGRL 713
           ***************************************************************************************** PP
   S: 340  akqrkqgrekkirplkrkrk 359
           +kqrk++r+k++rp+k+kr+
   Q: 714  HKQRKPDRRKRSRPYKAKRQ 733
           ******************97 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

ITKINTLLYS FAGLFTLLVE DFGVKGVQVE EIYDLQSKCQ GPVYGFIFLF KWIEERRSRR 60
KVSTLVDETS VIDEDIVNNM FFAHQLIPNS CATHALLSVL LNCNSVDLGP TLSRMKEFTK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTACAAAAA TTAATACTCT GTTATATTCT TTTGCAGGGC TCTTCACACT CTTAGTTGAG 60
GATTTTGGTG AGTATGTTGA TACACTAAGG GATGAACTTG TCCTTCTAAT TCTCATATAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0732--Signal

Interpro

IPR001578--Peptidase_C12_UCH

Pfam

PF01088--Peptidase_C12

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0035517--C:PR-DUB complex
GO:0003682--F:chromatin binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0061519--P:macrophage homeostasis
GO:0035522--P:monoubiquitinated histone H2A deubiquitination
GO:1903955--P:positive regulation of protein targeting to mitochondrion
GO:0016579--P:protein deubiquitination
GO:0071108--P:protein K48-linked deubiquitination
GO:0051726--P:regulation of cell cycle
GO:0001558--P:regulation of cell growth
GO:1900015--P:regulation of cytokine production involved in inflammatory response
GO:0010035--P:response to inorganic substance
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001263	Ailuropoda melanoleuca	78.64	0.00e+00	1039.00
IUUC-Apl-003405	Anas platyrhynchos	69.39	0.00e+00	636.00
IUUC-Ame-011946	Astyanax mexicanus	61.16	0.00e+00	852.00
IUUC-Bta-013131	Bos taurus	75.62	0.00e+00	889.00
IUUC-Cja-019599	Callithrix jacchus	80.49	0.00e+00	1085.00
IUUC-Cfa-021003	Canis familiaris	79.67	0.00e+00	1032.00
IUUC-Cpo-022143	Cavia porcellus	80.49	0.00e+00	1080.00
IUUC-Csa-023477	Chlorocebus sabaeus	79.67	0.00e+00	1067.00
IUUC-Cho-024734	Choloepus hoffmanni	65.64	5.00e-173	600.00
IUUC-Csv-025842	Ciona savignyi	61.00	1.00e-88	319.00
IUUC-Dre-027793	Danio rerio	63.86	0.00e+00	893.00
IUUC-Dno-029253	Dasypus novemcinctus	80.22	0.00e+00	1085.00
IUUC-Dor-030891	Dipodomys ordii	74.31	0.00e+00	995.00
IUUC-Dme-031796	Drosophila melanogaster	59.77	8.00e-87	313.00
IUUC-Ete-032646	Echinops telfairi	74.60	9.00e-147	513.00
IUUC-Eca-033805	Equus caballus	80.08	0.00e+00	1060.00
IUUC-Eeu-035216	Erinaceus europaeus	78.45	6.00e-127	447.00
IUUC-Fca-035611	Felis catus	79.39	0.00e+00	1012.00
IUUC-Fal-037186	Ficedula albicollis	81.53	0.00e+00	1022.00
IUUC-Gmo-038824	Gadus morhua	68.00	3.00e-171	595.00
IUUC-Gga-040875	Gallus gallus	80.88	0.00e+00	1095.00
IUUC-Gac-042226	Gasterosteus aculeatus	67.99	0.00e+00	907.00
IUUC-Ggo-045122	Gorilla gorilla	79.67	0.00e+00	1083.00
IUUC-Hsa-045882	Homo sapiens	79.67	0.00e+00	1082.00
IUUC-Itr-048185	Ictidomys tridecemlineatus	80.08	0.00e+00	1074.00
IUUC-Lch-049960	Latimeria chalumnae	72.40	0.00e+00	965.00
IUUC-Loc-052408	Lepisosteus oculatus	72.94	1.00e-177	616.00
IUUC-Laf-054187	Loxodonta africana	79.81	0.00e+00	1079.00
IUUC-Mcc-055273	Macaca mulatta	79.80	0.00e+00	1058.00
IUUC-Meu-056267	Macropus eugenii	77.25	0.00e+00	1050.00
IUUC-Mga-059958	Meleagris gallopavo	87.74	5.00e-156	543.00
IUUC-Mmr-061280	Microcebus murinus	79.15	0.00e+00	1054.00
IUUC-Mdo-062625	Monodelphis domestica	81.18	0.00e+00	1141.00
IUUC-Mmu-063853	Mus musculus	79.26	0.00e+00	1086.00
IUUC-Mlu-067771	Myotis lucifugus	80.49	0.00e+00	1051.00
IUUC-Opr-070741	Ochotona princeps	79.26	0.00e+00	1079.00
IUUC-Ont-072172	Oreochromis niloticus	66.76	0.00e+00	925.00
IUUC-Oan-073167	Ornithorhynchus anatinus	76.17	0.00e+00	1067.00
IUUC-Ocu-074176	Oryctolagus cuniculus	79.06	0.00e+00	1044.00
IUUC-Ola-087203	Oryzias latipes	84.65	3.00e-127	447.00
IUUC-Oga-089153	Otolemur garnettii	79.64	0.00e+00	1078.00
IUUC-Oar-090008	Ovis aries	78.16	0.00e+00	1045.00
IUUC-Ptr-091234	Pan troglodytes	79.53	0.00e+00	1080.00
IUUC-Pan-092005	Papio anubis	79.53	0.00e+00	1078.00
IUUC-Psi-093995	Pelodiscus sinensis	83.77	0.00e+00	662.00
IUUC-Pma-094110	Petromyzon marinus	45.50	7.00e-119	421.00
IUUC-Pfo-097418	Poecilia formosa	64.54	0.00e+00	902.00
IUUC-Pab-098267	Pongo abelii	79.40	0.00e+00	1055.00
IUUC-Pca-101084	Procavia capensis	78.65	0.00e+00	1018.00
IUUC-Pva-102292	Pteropus vampyrus	80.82	0.00e+00	744.00
IUUC-Rno-105251	Rattus norvegicus	77.87	0.00e+00	1053.00
IUUC-Sha-107100	Sarcophilus harrisii	81.18	0.00e+00	1157.00
IUUC-Sar-113559	Sorex araneus	75.79	0.00e+00	947.00
IUUC-Ssc-115688	Sus scrofa	79.26	0.00e+00	1064.00
IUUC-Tgu-117424	Taeniopygia guttata	82.48	0.00e+00	1140.00
IUUC-Tru-118585	Takifugu rubripes	65.95	0.00e+00	906.00
IUUC-Tsy-119299	Tarsius syrichta	69.42	0.00e+00	783.00
IUUC-Tni-120808	Tetraodon nigroviridis	65.00	0.00e+00	904.00
IUUC-Tbe-127705	Tupaia belangeri	79.08	9.00e-149	519.00
IUUC-Ttr-128225	Tursiops truncatus	78.98	0.00e+00	1035.00
IUUC-Vpa-130193	Vicugna pacos	77.87	5.00e-107	381.00
IUUC-Xtr-132449	Xenopus tropicalis	76.06	6.00e-168	583.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence