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Tag Content
UUCD2 ID IUUC-Cre-022938
UUCD1 version UUC-ChR-00389
Ensembl Protein ID EDO96917
UniProt Accession A8JGS8; A8JGS8_CHLRE
Genbank Protein ID EDO96917.1
Protein Name Coatomer subunit beta'
Genbank Nucleotide ID DS496186
Gene Name COPB2; CHLREDRAFT_154280
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
CHLREDRAFT_154280 EDO96917 EDO96917
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 4.60e-34 114.5 183 221
UBD/Beta-Prp 4.80e-69 232.3 14 300
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf...sd.tllvsGsdDgtikvWDlrtgvl 35
    gH+ +v+c+++ d ++l+sG+dD+ +kvWD+ t +
   Q: 183 GHEKGVNCVDYfngGDrPFLISGADDKLVKVWDYQTKAC 221
    8********976997789***************988766 PP
   


   UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdkl 109
    ++++++ v+++p ++++++ ++g + +w++ +++l++s++ e +v+a kf +++++ +tgs+D++i+v++++t + v t+++h+d+++++++sp+ ++
   Q: 14 RTDRVKGVDVHPTEPWVLANLYNGNVYIWNYLDQTLVKSFEVTELPVRAAKFVSRKQWVITGSDDMFIRVYNYNTMDKVKTFEAHTDYIRCITISPTMPYI 114
    578999*********************************************************************************************** PP
   S: 110 vsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsng..kelvsgsldgtvklw 207
    ++ s+d i++wd+e+g+ ++++gh++ v+ v+++p++ n ++s+slDrt+++W+l + + tl+g h++ v+++++ g ++l+sg++d+ vk+w
   Q: 115 LTSSDDMLIKLWDWEKGWNCVQVFEGHSHYVMQVSFNPKDtNTFASASLDRTIKVWSLGQPTPNFTLEG-HEKGVNCVDYFNGGdrPFLISGADDKLVKVW 214
    ******************8888**********************************************9.*********5444445*************** PP
   S: 208 dlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgsedskvniwklk 295
    d+qt+ cv tl+gh+ n++s f+p+ ++v+gs+Dg++++W +++ l +tl ++ ++v+s + +++++++ + d ++k
   Q: 215 DYQTKACVTTLEGHQHNISSAIFHPELPIIVTGSEDGTVKVWHSTTYRLENTLDYRMERVWSLGY--AKGSNCIAIGYDEGCVMLKIG 300
    **************************************************************998..777777777776666666665 PP
   

Organism Chlamydomonas reinhardtii
Functional Description
(View)

Functional Description



     The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
Protein Sequence
(Fasta)
MPLRLDIKKQ LVQRTDRVKG VDVHPTEPWV LANLYNGNVY IWNYLDQTLV KSFEVTELPV 60
RAAKFVSRKQ WVITGSDDMF IRVYNYNTMD KVKTFEAHTD YIRCITISPT MPYILTSSDD 120
It may take some time, please wait.

Protein Fasta Sequence



>IUUC-Cre-022938|E3,WD_repeat;UBD,Beta-Prp|Chlamydomonas reinhardtii
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TAGGTGCAGG GACTTCTGCA CAAAGAATTT TGGCGACGAC TGTGAACAGC ATCACGCGAC 60
AAGGCCTGCG CTGAGCCTGG ACGCAAAGTA GCGATCCTTC CCTGCCCTTC GGGCGCTTTT 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Cre-022938|E3,WD_repeat;UBD,Beta-Prp|Chlamydomonas reinhardtii
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0968--Cytoplasmic vesicle
KW-0931--ER-Golgi transport
KW-0333--Golgi apparatus
KW-0472--Membrane
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR006692--Coatomer_WD-assoc_reg
IPR016453--COPB2
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04053--Coatomer_WDAD
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0030126--C:COPI vesicle coat
GO:0000139--C:Golgi membrane
GO:0005198--F:structural molecule activity
GO:0006888--P:ER to Golgi vesicle-mediated transport
GO:0006891--P:intra-Golgi vesicle-mediated transport
GO:0006886--P:intracellular protein transport
GO:0006890--P:retrograde vesicle-mediated transport, Golgi to ER

KEGG cre:CHLREDRAFT_154280
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000222 Aegilops tauschii 66.72 0.00e+00 842.00
IUUC-Aml-002154 Ailuropoda melanoleuca 58.62 0.00e+00 1022.00
IUUC-Atr-003090 Amborella trichopoda 64.23 0.00e+00 1129.00
IUUC-Apl-003976 Anas platyrhynchos 58.86 0.00e+00 1026.00
IUUC-Aca-004301 Anolis carolinensis 58.91 0.00e+00 1033.00
IUUC-Aly-006508 Arabidopsis lyrata 64.40 0.00e+00 1137.00
IUUC-Ath-007635 Arabidopsis thaliana 64.00 0.00e+00 1125.00
IUUC-Ago-007914 Ashbya gossypii 45.73 0.00e+00 692.00
IUUC-Acl-008237 Aspergillus clavatus 54.19 0.00e+00 894.00
IUUC-Afl-008535 Aspergillus flavus 53.30 0.00e+00 848.00
IUUC-Afu-008845 Aspergillus fumigatus 53.83 0.00e+00 874.00
IUUC-Ani-009135 Aspergillus nidulans 53.77 0.00e+00 863.00
IUUC-Ang-009654 Aspergillus niger 55.59 0.00e+00 818.00
IUUC-Aor-009939 Aspergillus oryzae 53.87 0.00e+00 904.00
IUUC-Ate-010355 Aspergillus terreus 53.51 0.00e+00 861.00
IUUC-Ame-010922 Astyanax mexicanus 54.55 0.00e+00 903.00
IUUC-Bgr-012249 Blumeria graminis 52.29 0.00e+00 849.00
IUUC-Bta-013579 Bos taurus 58.90 0.00e+00 915.00
IUUC-Bci-013866 Botrytis cinerea 53.31 0.00e+00 841.00
IUUC-Bdi-015046 Brachypodium distachyon 66.10 0.00e+00 1122.00
IUUC-Bol-016012 Brassica oleracea 65.25 0.00e+00 1141.00
IUUC-Bra-017758 Brassica rapa 64.85 0.00e+00 1132.00
IUUC-Cel-018387 Caenorhabditis elegans 53.82 0.00e+00 955.00
IUUC-Cja-019145 Callithrix jacchus 58.55 0.00e+00 1025.00
IUUC-Cfa-020564 Canis familiaris 58.67 0.00e+00 1026.00
IUUC-Cpo-022201 Cavia porcellus 58.62 0.00e+00 1025.00
IUUC-Csa-023383 Chlorocebus sabaeus 63.09 0.00e+00 806.00
IUUC-Cho-024454 Choloepus hoffmanni 55.84 0.00e+00 883.00
IUUC-Cin-025681 Ciona intestinalis 59.15 0.00e+00 972.00
IUUC-Csv-026012 Ciona savignyi 59.27 0.00e+00 966.00
IUUC-Cgl-026649 Colletotrichum gloeosporioides 48.71 0.00e+00 749.00
IUUC-Cne-026986 Cryptococcus neoformans 53.82 0.00e+00 880.00
IUUC-Cme-027219 Cyanidioschyzon merolae 50.85 0.00e+00 819.00
IUUC-Dre-027846 Danio rerio 59.20 0.00e+00 1030.00
IUUC-Dor-030462 Dipodomys ordii 55.89 0.00e+00 799.00
IUUC-Dse-031268 Dothistroma septosporum 52.57 0.00e+00 853.00
IUUC-Dme-031791 Drosophila melanogaster 55.10 0.00e+00 934.00
IUUC-Ete-033166 Echinops telfairi 56.17 0.00e+00 680.00
IUUC-Eca-034180 Equus caballus 56.85 0.00e+00 978.00
IUUC-Eeu-035086 Erinaceus europaeus 45.75 4.00e-103 367.00
IUUC-Fca-036265 Felis catus 58.67 0.00e+00 1025.00
IUUC-Fal-037202 Ficedula albicollis 58.29 0.00e+00 980.00
IUUC-Fox-037711 Fusarium oxysporum 53.32 0.00e+00 818.00
IUUC-Fso-038268 Fusarium solani 52.82 0.00e+00 813.00
IUUC-Gmo-039046 Gadus morhua 59.61 0.00e+00 1025.00
IUUC-Ggr-039863 Gaeumannomyces graminis 53.33 0.00e+00 838.00
IUUC-Gga-041112 Gallus gallus 58.79 0.00e+00 1029.00
IUUC-Gac-041733 Gasterosteus aculeatus 59.20 0.00e+00 1004.00
IUUC-Gma-042910 Glycine max 64.95 0.00e+00 1168.00
IUUC-Ggo-044984 Gorilla gorilla 57.96 0.00e+00 1025.00
IUUC-Hsa-046698 Homo sapiens 57.84 0.00e+00 1025.00
IUUC-Hvu-047669 Hordeum vulgare 76.55 7.00e-178 614.00
IUUC-Itr-048212 Ictidomys tridecemlineatus 58.62 0.00e+00 1021.00
IUUC-Kpa-049265 Komagataella pastoris 49.81 0.00e+00 811.00
IUUC-Lch-050473 Latimeria chalumnae 59.32 0.00e+00 1034.00
IUUC-Lpe-050975 Leersia perrieri 66.34 0.00e+00 1116.00
IUUC-Loc-052675 Lepisosteus oculatus 59.56 0.00e+00 1035.00
IUUC-Lma-053218 Leptosphaeria maculans 52.39 0.00e+00 849.00
IUUC-Laf-053757 Loxodonta africana 58.60 0.00e+00 1018.00
IUUC-Mcc-054859 Macaca mulatta 58.55 0.00e+00 1025.00
IUUC-Meu-056174 Macropus eugenii 47.61 4.00e-87 314.00
IUUC-Mor-057264 Magnaporthe oryzae 54.01 0.00e+00 826.00
IUUC-Mpo-057538 Magnaporthe poae 52.59 0.00e+00 843.00
IUUC-Mtr-058618 Medicago truncatula 65.23 0.00e+00 1127.00
IUUC-Mla-058937 Melampsora laricipopulina 52.37 0.00e+00 845.00
IUUC-Mga-059875 Meleagris gallopavo 58.65 0.00e+00 1024.00
IUUC-Mvi-060240 Microbotryum violaceum 52.10 0.00e+00 869.00
IUUC-Mmr-061261 Microcebus murinus 58.67 0.00e+00 1026.00
IUUC-Mdo-062076 Monodelphis domestica 58.67 0.00e+00 1031.00
IUUC-Mmu-063324 Mus musculus 58.55 0.00e+00 1025.00
IUUC-Mac-064636 Musa acuminata 64.75 0.00e+00 1135.00
IUUC-Mpu-065961 Mustela putorius furo 58.67 0.00e+00 1024.00
IUUC-Mlu-067059 Myotis lucifugus 57.82 0.00e+00 995.00
IUUC-Nfi-068277 Neosartorya fischeri 53.41 0.00e+00 862.00
IUUC-Ncr-068659 Neurospora crassa 52.33 0.00e+00 849.00
IUUC-Nle-069034 Nomascus leucogenys 58.55 0.00e+00 1025.00
IUUC-Opr-070334 Ochotona princeps 59.10 0.00e+00 952.00
IUUC-Ont-071563 Oreochromis niloticus 59.44 0.00e+00 1032.00
IUUC-Oan-073416 Ornithorhynchus anatinus 58.29 0.00e+00 969.00
IUUC-Ocu-074522 Oryctolagus cuniculus 58.55 0.00e+00 1023.00
IUUC-Oba-075760 Oryza barthii 64.99 0.00e+00 1128.00
IUUC-Obr-076201 Oryza brachyantha 67.31 0.00e+00 1131.00
IUUC-Ogl-077450 Oryza glaberrima 65.71 0.00e+00 1153.00
IUUC-Ogu-078994 Oryza glumaepatula 64.99 0.00e+00 1128.00
IUUC-Oin-079856 Oryza indica 65.38 0.00e+00 1112.00
IUUC-Olo-080731 Oryza longistaminata 64.29 0.00e+00 1111.00
IUUC-Ome-081762 Oryza meridionalis 60.61 0.00e+00 1040.00
IUUC-Oni-082324 Oryza nivara 64.99 0.00e+00 1128.00
IUUC-Opu-083400 Oryza punctata 63.98 0.00e+00 1092.00
IUUC-Oru-084829 Oryza rufipogon 64.99 0.00e+00 1128.00
IUUC-Osa-086026 Oryza sativa 65.95 0.00e+00 1157.00
IUUC-Ola-087245 Oryzias latipes 59.06 0.00e+00 1025.00
IUUC-Olu-087655 Ostreococcus lucimarinus 64.19 0.00e+00 1088.00
IUUC-Oga-088163 Otolemur garnettii 56.54 0.00e+00 972.00
IUUC-Oar-089842 Ovis aries 58.42 0.00e+00 1023.00
IUUC-Ptr-090501 Pan troglodytes 58.55 0.00e+00 1025.00
IUUC-Pan-092011 Papio anubis 58.55 0.00e+00 1025.00
IUUC-Psi-093308 Pelodiscus sinensis 58.91 0.00e+00 1029.00
IUUC-Pma-094695 Petromyzon marinus 57.16 0.00e+00 934.00
IUUC-Pno-094785 Phaeosphaeria nodorum 60.00 2.00e-108 384.00
IUUC-Ppa-095412 Physcomitrella patens 64.36 0.00e+00 1157.00
IUUC-Pfo-096587 Poecilia formosa 59.32 0.00e+00 1030.00
IUUC-Pab-097926 Pongo abelii 56.77 0.00e+00 959.00
IUUC-Pop-099634 Populus trichocarpa 66.10 0.00e+00 1160.00
IUUC-Pca-100965 Procavia capensis 57.77 0.00e+00 991.00
IUUC-Ppe-101470 Prunus persica 65.95 0.00e+00 1164.00
IUUC-Pva-102451 Pteropus vampyrus 55.59 0.00e+00 803.00
IUUC-Pgr-103453 Puccinia graminis 52.38 0.00e+00 880.00
IUUC-Ptt-103868 Puccinia triticina 52.82 0.00e+00 871.00
IUUC-Pte-104274 Pyrenophora teres 53.12 0.00e+00 886.00
IUUC-Pyt-104794 Pyrenophora triticirepentis 51.34 0.00e+00 835.00
IUUC-Rno-105979 Rattus norvegicus 50.92 0.00e+00 770.00
IUUC-Sce-106269 Saccharomyces cerevisiae 46.03 0.00e+00 724.00
IUUC-Sha-106905 Sarcophilus harrisii 58.67 0.00e+00 1031.00
IUUC-Sja-107838 Schizosaccharomyces japonicus 45.82 0.00e+00 752.00
IUUC-Spo-108299 Schizosaccharomyces pombe 46.33 0.00e+00 774.00
IUUC-Smo-108695 Selaginella moellendorffii 66.34 0.00e+00 1134.00
IUUC-Sit-110239 Setaria italica 66.07 0.00e+00 1161.00
IUUC-Sly-111775 Solanum lycopersicum 66.83 0.00e+00 1137.00
IUUC-Stu-112906 Solanum tuberosum 66.05 0.00e+00 1033.00
IUUC-Sar-113472 Sorex araneus 54.63 0.00e+00 726.00
IUUC-Sbi-113801 Sorghum bicolor 66.99 0.00e+00 1156.00
IUUC-Sre-115040 Sporisorium reilianum 51.91 0.00e+00 859.00
IUUC-Ssc-115593 Sus scrofa 58.55 0.00e+00 1024.00
IUUC-Tgu-117239 Taeniopygia guttata 58.86 0.00e+00 1028.00
IUUC-Tru-118025 Takifugu rubripes 59.13 0.00e+00 1030.00
IUUC-Tsy-118824 Tarsius syrichta 55.64 0.00e+00 750.00
IUUC-Tni-120142 Tetraodon nigroviridis 59.27 0.00e+00 1023.00
IUUC-Tca-121613 Theobroma cacao 66.19 0.00e+00 1170.00
IUUC-Tre-122072 Trichoderma reesei 52.54 0.00e+00 849.00
IUUC-Tvi-122546 Trichoderma virens 52.54 0.00e+00 846.00
IUUC-Tae-125395 Triticum aestivum 65.71 0.00e+00 1154.00
IUUC-Tur-126103 Triticum urartu 63.98 0.00e+00 789.00
IUUC-Tme-127041 Tuber melanosporum 54.11 0.00e+00 884.00
IUUC-Tbe-127770 Tupaia belangeri 58.25 0.00e+00 841.00
IUUC-Ttr-129294 Tursiops truncatus 58.42 0.00e+00 1022.00
IUUC-Uma-129351 Ustilago maydis 51.02 0.00e+00 856.00
IUUC-Vda-129716 Verticillium dahliae 52.64 0.00e+00 869.00
IUUC-Vpa-130037 Vicugna pacos 46.97 8.00e-113 399.00
IUUC-Vvi-131689 Vitis vinifera 66.83 0.00e+00 1160.00
IUUC-Xtr-132633 Xenopus tropicalis 59.27 0.00e+00 1034.00
IUUC-Xma-133347 Xiphophorus maculatus 59.32 0.00e+00 1028.00
IUUC-Yli-134455 Yarrowia lipolytica 49.94 0.00e+00 774.00
IUUC-Zma-135706 Zea mays 66.87 0.00e+00 1161.00
Created Date 25-Jun-2017

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