iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062241

UUCD1 version

UUC-MoD-00497

Ensembl Protein ID

ENSMODP00000004665.2

UniProt Accession

F6ZJ64; F6ZJ64_MONDO

Protein Name

DCN1-like protein; Defective in cullin neddylation protein 1-like protein

Gene Name

DCUN1D2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000003808.2	ENSMODT00000004765.2	ENSMODP00000004665.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/DCUN1	2.90e-90	301.6	45	232

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/DCUN1

   S: 1    vskkkleelferYkdpqed.ligieglekfcedlgvdpediavLvlawkleaatlcefsreefldgltalgcdsieklqeklktlesel 88
           v+kkkle+l++rYkdpq++ +igi+g+++fc+dlg+dp++i+vLv+awk++aat+cefs++ef+dg+t+lgcd++ekl++ l+++e+el
   Q: 45   VDKKKLEQLYNRYKDPQDEnKIGIDGIQQFCDDLGLDPAHISVLVIAWKFRAATQCEFSKKEFMDGMTELGCDTTEKLKALLPRIEQEL 133
           589**************999********************************************************************* PP
   S: 89   kdeqkfkdiYrfafnfakdkgqksldldtaialwkLllaerefklldawlkfLeeekkksiskDtWnllLefskviakdlsnYdeegaW 177
           kd  kfkd+Y+f+fnfak++gqk+ldl++a+a+w+L+l++r fk+ld+w+kfL e++k+si+kDtWnllL+f ++ia+d+snYdeegaW
   Q: 134  KDAIKFKDFYQFTFNFAKNPGQKGLDLEMAVAYWNLVLSGR-FKFLDLWNKFLLEHHKRSIPKDTWNLLLDFGNMIADDMSNYDEEGAW 221
           ****************************************9.*********************************************** PP
   S: 178  PvliDefveyl 188
           PvliD+fvey+
   Q: 222  PVLIDDFVEYA 232
           *********97 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MTFTQAGEKT AIYCLMQNEW KLEVATDNYF QNPDLYYKES MKNSVDKKKL EQLYNRYKDP 60
QDENKIGIDG IQQFCDDLGL DPAHISVLVI AWKFRAATQC EFSKKEFMDG MTELGCDTTE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CATAAGTTTA AATCATCTCA GAAGGACAAG ATCCGTCAGT TTATGACATT TACCCAGGCT 60
GGTGAAAAGA CTGCTATATA CTGTTTAATG CAGAATGAGT GGAAACTAGA AGTGGCAACT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014764--DCN-prot
IPR011992--EF-hand-dom_pair
IPR005176--PONY_dom

PROSITE

PS51229--DCUN1

Pfam

PF03556--Cullin_binding

Gene Ontology

GO:0000151--C:ubiquitin ligase complex
GO:0097602--F:cullin family protein binding
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0032182--F:ubiquitin-like protein binding
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0045116--P:protein neddylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003933	Anas platyrhynchos	94.65	5.00e-139	486.00
IUUC-Aca-005059	Anolis carolinensis	93.69	1.00e-125	442.00
IUUC-Ame-011553	Astyanax mexicanus	89.21	1.00e-132	465.00
IUUC-Cja-018854	Callithrix jacchus	87.70	4.00e-130	456.00
IUUC-Cpo-021832	Cavia porcellus	86.99	4.00e-128	450.00
IUUC-Csa-023108	Chlorocebus sabaeus	87.30	1.00e-129	455.00
IUUC-Cgl-026386	Colletotrichum gloeosporioides	31.28	6.00e-23	100.00
IUUC-Dno-029524	Dasypus novemcinctus	91.80	5.00e-136	476.00
IUUC-Dor-030143	Dipodomys ordii	86.89	3.00e-128	450.00
IUUC-Fal-036715	Ficedula albicollis	94.24	7.00e-138	482.00
IUUC-Gga-040224	Gallus gallus	94.24	5.00e-139	486.00
IUUC-Ggo-044972	Gorilla gorilla	86.89	7.00e-129	452.00
IUUC-Hsa-046994	Homo sapiens	86.07	1.00e-128	452.00
IUUC-Hvu-047636	Hordeum vulgare	37.98	5.00e-23	100.00
IUUC-Itr-047902	Ictidomys tridecemlineatus	82.23	2.00e-123	434.00
IUUC-Lch-049751	Latimeria chalumnae	90.95	5.00e-135	473.00
IUUC-Laf-053972	Loxodonta africana	92.21	7.00e-137	479.00
IUUC-Mcc-054700	Macaca mulatta	87.30	8.00e-130	456.00
IUUC-Meu-056791	Macropus eugenii	84.84	1.00e-115	408.00
IUUC-Mga-060072	Meleagris gallopavo	93.83	5.00e-138	483.00
IUUC-Nle-069475	Nomascus leucogenys	86.48	1.00e-128	451.00
IUUC-Oan-072921	Ornithorhynchus anatinus	89.75	1.00e-132	465.00
IUUC-Ocu-074349	Oryctolagus cuniculus	85.06	3.00e-124	437.00
IUUC-Oga-088621	Otolemur garnettii	87.70	7.00e-130	456.00
IUUC-Ptr-091595	Pan troglodytes	86.48	3.00e-128	451.00
IUUC-Pan-092825	Papio anubis	87.30	7.00e-130	456.00
IUUC-Psi-093029	Pelodiscus sinensis	93.42	3.00e-136	476.00
IUUC-Pab-098197	Pongo abelii	86.89	6.00e-129	452.00
IUUC-Pca-100195	Procavia capensis	91.80	2.00e-134	471.00
IUUC-Pva-102691	Pteropus vampyrus	89.75	4.00e-133	467.00
IUUC-Sha-106542	Sarcophilus harrisii	100.00	6.00e-146	509.00
IUUC-Tgu-117196	Taeniopygia guttata	93.83	1.00e-137	482.00
IUUC-Tni-120542	Tetraodon nigroviridis	88.80	6.00e-132	462.00
IUUC-Tre-121986	Trichoderma reesei	28.14	3.00e-20	92.40
IUUC-Vda-129929	Verticillium dahliae	31.34	6.00e-22	98.20

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence