iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000020702.2	ENSCJAT00000040668.2	ENSCJAP00000038493.2
ENSCJAG00000020702.2	ENSCJAT00000061483.1	ENSCJAP00000048553.1
ENSCJAG00000020702.2	ENSCJAT00000040667.2	ENSCJAP00000038492.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.30e-08	35.4	14	57

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadCl.qkwpglknssskefrCPlCr 46
           C+iC+e++k+  +++ CgH+f++ Cl q++   k s+s+ + CPlCr
   Q: 14   CPICQESLKE-AMSTKCGHLFCRVCLkQHV--EKASASGVICCPLCR 57
           ********99.999************7777..8889**********8 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MIPLHKDTQE EGVCPICQES LKEAMSTKCG HLFCRVCLKQ HVEKASASGV ICCPLCRKPC 60
SEEVLGTGYI CLNHQKRVCR FCEESRLLLC LECLVSPEHT SHHELTIENA LSHYKVSPDP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGATCCCCT TGCATAAGGA CACCCAGGAG GAGGGTGTCT GCCCCATCTG CCAGGAGAGC 60
CTGAAGGAGG CCATGAGCAC CAAATGTGGA CATCTCTTCT GTCGAGTGTG CCTGAAACAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR000315--Znf_B-box
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00097--zf-C3HC4

SMART

SM00184--RING

Gene Ontology

GO:0008385--C:IkappaB kinase complex
GO:0008270--F:zinc ion binding
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:0042177--P:negative regulation of protein catabolic process
GO:1900181--P:negative regulation of protein localization to nucleus
GO:0045116--P:protein neddylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001427	Ailuropoda melanoleuca	49.80	3.00e-55	207.00
IUUC-Bta-012543	Bos taurus	55.84	2.00e-61	228.00
IUUC-Csa-023101	Chlorocebus sabaeus	73.31	3.00e-94	337.00
IUUC-Cho-024926	Choloepus hoffmanni	64.79	6.00e-24	104.00
IUUC-Dno-029338	Dasypus novemcinctus	45.04	3.00e-39	154.00
IUUC-Dor-030164	Dipodomys ordii	58.26	8.00e-61	226.00
IUUC-Dse-031337	Dothistroma septosporum	36.71	5.00e-09	55.10
IUUC-Ete-032446	Echinops telfairi	48.58	5.00e-48	184.00
IUUC-Eca-034042	Equus caballus	63.98	3.00e-76	277.00
IUUC-Eeu-034444	Erinaceus europaeus	48.46	6.00e-55	207.00
IUUC-Ggo-044410	Gorilla gorilla	78.43	2.00e-102	364.00
IUUC-Hsa-046211	Homo sapiens	78.43	1.00e-102	365.00
IUUC-Itr-048126	Ictidomys tridecemlineatus	57.98	2.00e-65	241.00
IUUC-Laf-054019	Loxodonta africana	50.98	1.00e-46	179.00
IUUC-Mcc-054616	Macaca mulatta	79.61	1.00e-108	385.00
IUUC-Meu-055981	Macropus eugenii	36.99	3.00e-35	141.00
IUUC-Mdo-062958	Monodelphis domestica	38.84	2.00e-37	148.00
IUUC-Mmu-063571	Mus musculus	54.69	8.00e-62	229.00
IUUC-Nle-069843	Nomascus leucogenys	83.49	2.00e-43	167.00
IUUC-Opr-071083	Ochotona princeps	54.12	3.00e-67	248.00
IUUC-Ocu-073939	Oryctolagus cuniculus	60.47	2.00e-67	248.00
IUUC-Oga-088040	Otolemur garnettii	66.41	7.00e-81	293.00
IUUC-Oar-089914	Ovis aries	59.13	3.00e-72	264.00
IUUC-Ptr-091240	Pan troglodytes	69.72	1.00e-88	318.00
IUUC-Pan-092095	Papio anubis	77.97	4.00e-93	333.00
IUUC-Pab-098406	Pongo abelii	78.04	7.00e-103	366.00
IUUC-Pca-101043	Procavia capensis	50.00	4.00e-52	197.00
IUUC-Pva-102651	Pteropus vampyrus	59.92	3.00e-75	275.00
IUUC-Rno-106090	Rattus norvegicus	55.46	5.00e-61	227.00
IUUC-Smo-109224	Selaginella moellendorffii	44.68	2.00e-05	43.50
IUUC-Ssc-115942	Sus scrofa	60.31	9.00e-76	276.00
IUUC-Tsy-119497	Tarsius syrichta	66.67	6.00e-87	313.00
IUUC-Tbe-127279	Tupaia belangeri	63.82	3.00e-74	271.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence