iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-004998

Ensembl Protein ID

ENSACAP00000003243.2

UniProt Accession

G1KBS7; G1KBS7_ANOCA

Protein Name

Uncharacterized protein

Gene Name

TBK1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000003232.2	ENSACAT00000003326.2	ENSACAP00000003243.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
ULD/UDP/UBQ/UBQ_Other	81.76	0.00e+00	1283.00	IUUC-Mmu-064107

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MQSTSNYLWL LSDILGQGAT ANVFRGRHKK TGDLYAVKVF NNFSFLRPVD VQMREFEVLK 60
KLNHKNIVKL FAIEEETTSR HKVLVMEFCP CGSLYTVLEE PSNAYGLPET EFLIVLKDVV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCAGAGTA CGTCCAATTA TCTCTGGCTC CTGTCAGACA TCTTGGGCCA AGGAGCGACT 60
GCAAATGTTT TCCGTGGAAG ACACAAGGTT TGTACAGAGG CAGAAATGCT ATCTGTTCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM

Pfam

PF00069--Pkinase

SMART

SM00220--S_TKc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0003676--F:nucleic acid binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0002218--P:activation of innate immune response
GO:0050830--P:defense response to Gram-positive bacterium
GO:0044565--P:dendritic cell proliferation
GO:0045087--P:innate immune response
GO:0010629--P:negative regulation of gene expression
GO:0018105--P:peptidyl-serine phosphorylation
GO:0018107--P:peptidyl-threonine phosphorylation
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0032727--P:positive regulation of interferon-alpha production
GO:0045359--P:positive regulation of interferon-beta biosynthetic process
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:1904417--P:positive regulation of xenophagy

KEGG

acs:100553575

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001638	Ailuropoda melanoleuca	82.58	0.00e+00	1288.00
IUUC-Apl-004028	Anas platyrhynchos	86.28	0.00e+00	1336.00
IUUC-Ame-011617	Astyanax mexicanus	69.38	0.00e+00	1050.00
IUUC-Bta-012799	Bos taurus	82.44	0.00e+00	1287.00
IUUC-Cja-019357	Callithrix jacchus	82.47	0.00e+00	1285.00
IUUC-Cfa-020309	Canis familiaris	82.72	0.00e+00	1290.00
IUUC-Cpo-022062	Cavia porcellus	82.30	0.00e+00	1279.00
IUUC-Csa-023517	Chlorocebus sabaeus	82.72	0.00e+00	1290.00
IUUC-Cho-025037	Choloepus hoffmanni	76.36	0.00e+00	808.00
IUUC-Cin-025580	Ciona intestinalis	42.38	6.00e-153	534.00
IUUC-Csv-025818	Ciona savignyi	40.81	6.00e-146	511.00
IUUC-Dre-027527	Danio rerio	69.09	0.00e+00	1056.00
IUUC-Dno-029475	Dasypus novemcinctus	71.95	0.00e+00	974.00
IUUC-Dme-031698	Drosophila melanogaster	39.67	5.00e-137	481.00
IUUC-Ete-033090	Echinops telfairi	71.19	0.00e+00	1066.00
IUUC-Eca-033996	Equus caballus	82.85	0.00e+00	1289.00
IUUC-Eeu-035082	Erinaceus europaeus	76.57	0.00e+00	765.00
IUUC-Fca-035921	Felis catus	79.37	0.00e+00	1230.00
IUUC-Fal-037406	Ficedula albicollis	85.73	0.00e+00	1337.00
IUUC-Gmo-038721	Gadus morhua	71.19	0.00e+00	1053.00
IUUC-Gga-041234	Gallus gallus	85.19	0.00e+00	1328.00
IUUC-Gac-042315	Gasterosteus aculeatus	71.45	0.00e+00	1065.00
IUUC-Ggo-044885	Gorilla gorilla	76.95	0.00e+00	1178.00
IUUC-Hsa-046847	Homo sapiens	82.44	0.00e+00	1288.00
IUUC-Itr-047906	Ictidomys tridecemlineatus	81.77	0.00e+00	1274.00
IUUC-Lch-049731	Latimeria chalumnae	54.34	0.00e+00	780.00
IUUC-Loc-051879	Lepisosteus oculatus	73.42	0.00e+00	1107.00
IUUC-Laf-054232	Loxodonta africana	82.19	0.00e+00	1277.00
IUUC-Mcc-055447	Macaca mulatta	82.72	0.00e+00	1291.00
IUUC-Meu-056138	Macropus eugenii	93.03	0.00e+00	657.00
IUUC-Mga-059460	Meleagris gallopavo	84.40	0.00e+00	1303.00
IUUC-Mmr-061445	Microcebus murinus	82.72	0.00e+00	1291.00
IUUC-Mmu-064107	Mus musculus	81.76	0.00e+00	1261.00
IUUC-Mpu-066834	Mustela putorius furo	82.72	0.00e+00	1291.00
IUUC-Mlu-068006	Myotis lucifugus	81.51	0.00e+00	1250.00
IUUC-Nle-069280	Nomascus leucogenys	82.44	0.00e+00	1289.00
IUUC-Opr-070728	Ochotona princeps	73.97	0.00e+00	1011.00
IUUC-Ont-071621	Oreochromis niloticus	71.51	0.00e+00	1078.00
IUUC-Oan-073162	Ornithorhynchus anatinus	82.00	0.00e+00	1226.00
IUUC-Ocu-074787	Oryctolagus cuniculus	83.01	0.00e+00	1292.00
IUUC-Ola-086737	Oryzias latipes	33.04	2.00e-28	120.00
IUUC-Oga-088764	Otolemur garnettii	81.89	0.00e+00	1285.00
IUUC-Oar-090333	Ovis aries	82.33	0.00e+00	1283.00
IUUC-Ptr-090568	Pan troglodytes	82.17	0.00e+00	1285.00
IUUC-Pan-091979	Papio anubis	82.49	0.00e+00	1283.00
IUUC-Psi-093336	Pelodiscus sinensis	86.01	0.00e+00	1322.00
IUUC-Pma-094200	Petromyzon marinus	43.06	4.00e-171	594.00
IUUC-Pfo-096354	Poecilia formosa	71.17	0.00e+00	1073.00
IUUC-Pab-098499	Pongo abelii	82.58	0.00e+00	1288.00
IUUC-Pva-102454	Pteropus vampyrus	81.89	0.00e+00	1265.00
IUUC-Rno-105595	Rattus norvegicus	81.48	0.00e+00	1247.00
IUUC-Sha-106864	Sarcophilus harrisii	83.20	0.00e+00	1291.00
IUUC-Sar-113728	Sorex araneus	74.29	0.00e+00	1080.00
IUUC-Tgu-117200	Taeniopygia guttata	85.11	0.00e+00	1324.00
IUUC-Tsy-119017	Tarsius syrichta	81.99	0.00e+00	950.00
IUUC-Tni-120724	Tetraodon nigroviridis	71.49	0.00e+00	1075.00
IUUC-Tbe-127887	Tupaia belangeri	75.26	0.00e+00	915.00
IUUC-Ttr-129111	Tursiops truncatus	75.99	0.00e+00	1158.00
IUUC-Vpa-130724	Vicugna pacos	82.99	0.00e+00	1295.00
IUUC-Xtr-132091	Xenopus tropicalis	75.79	0.00e+00	1174.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence