iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000000013.1	ENSLACT00000000016.1	ENSLACP00000000015.1
ENSLACG00000000013.1	ENSLACT00000000017.1	ENSLACP00000000016.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	6.10e-54	181.8	8	137
UBD/UBC-like/UBD_UBC	5.20e-79	263.3	8	138

Active Site

Position(s)	Description	Evidence
86	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 3    kkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeek 91
           k+el++l++dpp+++sa+pv + d+++w+++i+Gp+d+pY+ggvF l+i+fp+dYPfkPPkv f+t+i+hPn+++nG++Cl+il+  ++
   Q: 8    KEELNDLARDPPAQCSAGPVGD-DMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILR--SQ 93
           579*******************.9************************************************************9..** PP
   S: 92   Wspalsvesvllsiqsllaepnpesplneeaaellkknreeykk 135
           Wspal++++vllsi+sll++pnp++pl  e+a+++k++re++++
   Q: 94   WSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDRENFSR 137
           ****************************************9975 PP

UBD/UBC-like/UBD_UBC

   S: 3    kkelkdllrdeeaqisadlvdddlfelratiagppdspyeggvffltiklptdypfkppkvafitkiyhpninsngsicldilrsqwsa 91
           k el+dl+rd++aq+sa++v+dd+f+++ati+gp+dspy+ggvfflti++ptdypfkppkvaf+t+iyhpninsngsicldilrsqws+
   Q: 8    KEELNDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSP 96
           679************************************************************************************** PP
   S: 92   altlskvllslcslladaepddplvaeiariyktdkekykri 133
           alt+skvlls+csll+d++pddplv+eiariyktd+e++ r+
   Q: 97   ALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDRENFSRV 138
           ***************************************997 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

LHVVYFRKEE LNDLARDPPA QCSAGPVGDD MFHWQATIMG PNDSPYQGGV FFLTIHFPTD 60
YPFKPPKVAF TTRIYHPNIN SNGSICLDIL RSQWSPALTI SKVLLSICSL LCDPNPDDPL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGCTCA AGAGAATTCA CAAGGTAAGC TGGCACCTAA CGGCCGCGGC GCCCAGCTGC 60
TTTGCCTGCC TGCCTGCCTC CTCCTCCTCC CCGGCCCGCA CACACGCTCT GTCTCTCTCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005524--F:ATP binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003199	Anas platyrhynchos	92.03	3.00e-73	266.00
IUUC-Dno-028952	Dasypus novemcinctus	88.89	3.00e-74	270.00
IUUC-Ete-032295	Echinops telfairi	92.03	3.00e-73	266.00
IUUC-Eca-033293	Equus caballus	90.78	2.00e-74	270.00
IUUC-Ggo-045375	Gorilla gorilla	90.14	2.00e-74	270.00
IUUC-Itr-048882	Ictidomys tridecemlineatus	90.14	3.00e-74	270.00
IUUC-Loc-052788	Lepisosteus oculatus	91.37	5.00e-73	266.00
IUUC-Laf-053580	Loxodonta africana	91.37	2.00e-73	267.00
IUUC-Mcc-054673	Macaca mulatta	92.03	2.00e-73	267.00
IUUC-Meu-056462	Macropus eugenii	89.86	2.00e-71	260.00
IUUC-Mmr-061474	Microcebus murinus	92.03	3.00e-73	266.00
IUUC-Oan-072881	Ornithorhynchus anatinus	98.41	3.00e-71	259.00
IUUC-Pma-094405	Petromyzon marinus	93.08	7.00e-71	258.00
IUUC-Pva-102817	Pteropus vampyrus	100.00	4.00e-71	260.00
IUUC-Sar-113302	Sorex araneus	92.03	3.00e-73	266.00
IUUC-Tsy-119491	Tarsius syrichta	89.13	1.00e-68	252.00
IUUC-Tbe-128122	Tupaia belangeri	91.13	1.00e-57	214.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence